LOCUS       XM_006247437            5486 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus Rho GTPase activating protein 23
            (Arhgap23), transcript variant X1, mRNA.
ACCESSION   XM_006247437
VERSION     XM_006247437.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051345.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006247437.3.
            
            On Jan 21, 2021 this sequence version replaced XM_006247437.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5486
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5486
                     /gene="Arhgap23"
                     /note="Rho GTPase activating protein 23; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 46 ESTs, 1 long SRA read, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     140 samples with support for all annotated introns"
                     /db_xref="GeneID:303501"
                     /db_xref="RGD:1309742"
     CDS             86..4237
                     /gene="Arhgap23"
                     /codon_start=1
                     /product="rho GTPase-activating protein 23 isoform X1"
                     /protein_id="XP_006247499.1"
                     /db_xref="GeneID:303501"
                     /db_xref="RGD:1309742"
                     /translation="MDTIFVKNVKEGGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIG
                     LIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEARSIPEPPPLCYPRKTYA
                     PPTRAPAWATMVPEPISALPTDPRSPAAWSDPGSRVTSATRAHLDNSSLGMSQPRPSP
                     GAFPHLPSESRTPRAFLESGSRVLPSRLECQQALSHWLSNQIPRRAGERRCPAMPPRA
                     RSASQDRLEDVTTHHPWPCSTSQDALSQLGQEGWHRARSDDYLSRATRSAEALGPGAL
                     VSPRLERCGWASQRSSARTSACPSRDLPGPQAPPASGLQGLDDIGYIGYRSYSPSFQR
                     RTGLLHALSFRDSPFGGLPTFSLAQSPASFPPEASEPPRVARPDPSTRALEPPAEDHR
                     DEVVLRQKPPTGRKVQLTPARQVNLGFGDESLEPEARGERPGRKVAPLATTEDSLASI
                     PFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFALSRHYSQDCSSI
                     KAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRVPSLRMLRSFFTDGSLDS
                     WGTSEDAEAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGGGLRQWKRVYA
                     VLRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRL
                     TTADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSS
                     GPKADSSPKGSRGLGGLKSEFLKQTAVRGLRTQDQPAGSKEDSVTTPKTPWGINIIKK
                     NKKAAPRAFGIRLEDCQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSS
                     LQEQLNRGPSDINLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDS
                     RERMKTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTS
                     EDNMTDMVTHMPDRYKIVETLIQHSDWFFSDDEDKGERTPVDDKEPQSVPNIEYLLPN
                     IGRTVPPSDPGSADSTTCSSAKSKGSWVPKKEPYAREMLAISFISAVNRKRKKRREAR
                     GLGSSTDDDSEQEAHKAAVGTQEPPEGQLPGPSAEEAPGRLSPSTAPDERPAADTRSI
                     VSGYSTLSTMDRSVCSGTGGRRAGAGDEADDERSELSHVETDTEGGAGPGGRLARRPS
                     FSSHHLMPCDTLARRRLSRSRADAEGPRGPEPLGSASSSSQESLRPPAAAPVLGSRPS
                     RVEALRLRLRGTADDMLAVRLRRPLSPETRRRRSSWRRHTVVVQSPLTDLNFNEWKEL
                     DGGGPPESAGVRPHSDNKDSGLSSLESTKARASSAASLPSGDLGALQGLPARRSAAAR
                     LHQCL"
ORIGIN      
        1 aggaggaaga ggaggaagag gaggaagagg agcaggagga agaggaggag gaggaggacc
       61 ctctccccgg caccgtctgg agcccatgga taccatcttt gtgaagaatg tgaaggaggg
      121 gggccccgcc cacagggcag ggcttcgcac aggagaccgg ctggtgaagg tgaatggaga
      181 gagcgtcatt gggaagacat actcccaggt cataggtctg atccagaaca gcgatgacac
      241 cctggagctc tccatcatgc ccaaggatga ggacatccta cagctggcct actcccagga
      301 tgcctacctg aagggcaacg agccgtattc tggagaggcc cgcagcatcc cagaaccacc
      361 tccactctgc tacccacgga agacctatgc cccgccaacc cgggcccctg cctgggccac
      421 tatggtgcct gagcccatct cagcactacc tacggatccc cggagtcctg ctgcctggag
      481 tgacccaggg tcccgtgtta catctgccac ccgtgcccac ctggacaact cttccctggg
      541 gatgagccag ccccgcccaa gccctggtgc ctttccccac ctcccttcag agtcccggac
      601 gccccgtgcc ttcctagagt ctggcagccg ggtgcttccc agcagactgg agtgccagca
      661 ggctctgtca cactggctgt caaatcagat accccgcagg gcgggggaga gacggtgccc
      721 agccatgcca cctcgggccc gcagtgcctc ccaggaccgc ttggaggatg tgactaccca
      781 ccacccatgg ccctgctcca cctcccagga tgccttgagc cagctgggcc aggagggttg
      841 gcaccgagct cgctcagacg attacctgag ccgggctacc cgctctgctg aagcactggg
      901 gccaggggca ctggtgtcac ctcgccttga acgctgcggt tgggcttccc agcggtcatc
      961 tgcccgcacc tctgcttgcc cttctcggga cttgccaggg ccccaggccc ctcccgcatc
     1021 tggcctgcag ggcctggatg acatcgggta cattgggtat cggagctata gcccatcatt
     1081 ccagcgccgg actggtctcc tgcatgccct ctccttccgg gactcaccct tcgggggact
     1141 tcccaccttc agcttggccc agtctcctgc atcattccca ccagaggcct ccgaaccacc
     1201 tagggtcgcc cggccagatc ctagcacccg agccctggag cctcccgcag aggatcatcg
     1261 tgatgaggtg gtcctgagac agaaacctcc aactggtcgc aaggtccagc tgaccccagc
     1321 aaggcaggtg aaccttggat ttggtgacga gtccctagaa ccagaggcca gaggggaacg
     1381 tccaggcagg aaggtggccc ctttggccac tacagaagac tccctggctt caattccctt
     1441 cattgatgag cccaccagcc ccagcattga ccttcaagcc aagcatgtcc ctgcctccgc
     1501 cgtggtctcc agtgccatga actcagcccc tgtcctggga actagcccat cctcacccac
     1561 cttcactttt gccctcagcc gccattactc ccaggactgc agcagcatca aggccggtcg
     1621 ccgctcctcc tacctgttgg ccatcaccac agagcgctcc aagtcctgtg atgatggact
     1681 gaataccttc cgggatgagg gccgagtgct ccggcgcctt cccaaccgtg tgccgagcct
     1741 acggatgctg cgaagcttct tcaccgacgg gtctctagat agctggggca cctctgaaga
     1801 tgctgaagcc ccctctaaac gacactcaac ctctgacctc tcagatgcaa ccttcagtga
     1861 tatcaggaga gaaggctggt tgtattataa gcagatcctc accaagaagg ggaagaaagc
     1921 gggcggcggc ctgcgccagt ggaagcgcgt ctatgccgtc ctgcgggcgc gctcgctctc
     1981 gttgagcaag gagcggcggg agcccgggcc ggcggctgcg ggggctgcgg cggccggcgc
     2041 aggtgaggac gaggcggcgc ccgtctgcat cggctcctgc ctggtggaca tctcctacag
     2101 cgagaccaag aggaggcacg tgttccggct gaccaccgct gacttctgtg aatatctctt
     2161 tcaggctgag gatcgggatg acatgctggg ctggatcaga gcgatccggg agaacagcag
     2221 ggccgagggc gaggaccccg gctgtgccaa ccaagctctg atcagcaaga agcttaatga
     2281 ttatcgcaaa gtgagccata gctctgggcc caaagccgat tcctccccta aaggctctcg
     2341 gggcctggga ggcctcaagt ctgaattcct caagcagact gcagtccgcg gcctcagaac
     2401 tcaggaccag cccgcaggaa gcaaggaaga cagtgttaca actcccaaaa ccccctgggg
     2461 tatcaacatt atcaagaaga acaagaaggc cgccccaagg gcatttggga tccgattgga
     2521 ggattgccag cctgccactg agaaccagcg tgtccccttg atcgtggctg cctgctgccg
     2581 tattgtggag gcacggggac tggaatcaac tggcatttac cgggtacctg gcaacaatgc
     2641 agtggtgtct agcctgcagg agcagctcaa ccgtgggccc agtgacatca acctgcagga
     2701 tgagcgctgg caggacctca acgtgatcag cagcctgctt aaggctttct tccgcaagct
     2761 gccagagcct ctcttcactg acgacaaata caatgacttc atcgaggcca atcggataga
     2821 agattccaga gagaggatga agaccctgag gaagctgatc cgggatctcc caggacacta
     2881 ctatgaaaca cttaaattcc tcgtgggcca tctcaagacc attgctgacc actcagagaa
     2941 aaacaagatg gagccccgga acctggctct ggtctttggg ccgacgttgg taaggacatc
     3001 tgaagacaac atgacagaca tggtaacgca catgccggac cgctacaaga tcgtggagac
     3061 actaatccag cattctgact ggttcttcag tgatgatgag gacaaaggag agagaacccc
     3121 tgttgatgac aaggagccac aatcggtgcc caacatcgag tacctcctgc ccaacattgg
     3181 caggacagtg ccccccagtg atccaggctc agcagattcc accacctgca gttcagccaa
     3241 gtccaagggt tcgtgggtcc ccaagaaaga gccttatgcc cgggagatgc tggcgatctc
     3301 cttcatctct gcggtaaacc gcaaacggaa gaagcggcgg gaggcgcggg gcctgggtag
     3361 cagcaccgac gatgactccg agcaggaggc gcacaaggct gcggtgggga ctcaggagcc
     3421 acccgagggg cagctgccag ggccctcagc cgaggaggct cccggtcgcc tcagcccctc
     3481 gacagcaccc gacgagcgac ctgcggcgga cacgcgctcc atcgtctcgg gctattccac
     3541 cctgtccacc atggaccgta gcgtgtgctc gggcaccggc gggcggcgcg caggcgcggg
     3601 cgacgaggcg gacgacgaac gcagtgagct gagccacgtg gagacggaca cggagggtgg
     3661 cgctggcccc ggggggcgcc tggcgcgccg gccgtccttc agctcacacc atcttatgcc
     3721 atgcgacact ctggcgcgcc gtcgcctgtc tcgcagtcgc gcggatgccg agggtccccg
     3781 cggtccagag ccgctgggct cggcgtcatc cagcagccag gagtcgctga ggcctccggc
     3841 ggccgctccg gtactcggct cgcgaccttc gcgcgtggaa gccctgcggc tgcggctgcg
     3901 tggcaccgcc gacgacatgc tggccgttcg gctgcggcgc ccactgtcgc ccgagacgcg
     3961 gcggcgtcgg agcagctggc gccgccacac ggtggtggta cagagcccac taaccgacct
     4021 caacttcaac gagtggaagg agctggacgg agggggacct ccagagtccg ctggcgtgcg
     4081 accgcacagc gacaataagg actctggcct cagcagcctg gagtccacca aggcacgggc
     4141 ctcatccgcc gcatcactgc catcggggga cctaggggcc ctgcagggtc tgcccgcacg
     4201 ccgctcagct gccgcccgcc tccaccagtg tctgtgacac cctctccggt cccggggcag
     4261 caggagtctc cgtctcgtct gtgccccatt cagctgcctc cagtgctgcg gaaggttggg
     4321 ggcggggtgt gaagggcggt gctggtgccg caggcgggca taggagaagt ccgagctgga
     4381 ccgaagtggg agtccttagg agaggggagg ggttacgggg agttatgtcc cttggataaa
     4441 gaaccgagtg gcccttttct gtgagtccac ctagggactc ttggtgactc atgcagtgtg
     4501 ggtgaactac ccaagtttca tacagaagga gagatacagg ctgggttttg ggtctgccct
     4561 ctgccccacc aaccccatta gttcctggca aaggagaggg ggaggatgaa tgtctgggga
     4621 gcagttgggt gtccatggag agggggcttg tgtgtgtgtg agtgtgtgtg tttgtagtca
     4681 cagtgcaaag atgtttgttt ccagtagcaa tttctacccc aatcccttca tttccgacag
     4741 accccaagcc aggactctgc ctttggtgca cacagaaacc ttagccccaa gcttgtcagg
     4801 gcagaggctg ggttaaggcc acttccacag aggcaggact gaaccccact attacccgag
     4861 tcgttcctca catcctctaa gtcaccccct aagctctttg acctgtggac ctgcctgctt
     4921 ccattttttt ggagtgtcta ggaccccctg cagctggcat ctccttgttc accctgcttc
     4981 ctgccagttt agcatgccgg ctctcacttt caatcgggaa gaagtctgtc cggcactgat
     5041 ggatagggtc ttagccaggc tgttccagca gggtgggtgg gacccagctc ctctttcccc
     5101 acagtgtaaa taaacctaaa gcactagtcg cccctctgcc ctcactcatt ccaggggagc
     5161 cccagtgggg tgacctgccc tactgcccag gtctgtccat ctttctggtt tatgcaaaga
     5221 tttgctgtaa agtctctccc ctccctttca ctgtaaatat tgtctctaat gtgtaacata
     5281 taaagaattt ataaggattt ttaaagatgt tttgctcatt ttaaaaagtg ttgtaacagt
     5341 gttggataaa gcccccacgt ctgcatggct cctccactgt gttcttgaca cctctctagg
     5401 ctataactaa gatccctgct tctgaaagcc ctgtcgtaaa agtacagtct atgtcttgga
     5461 aataaatggc cgtcctcagg catgaa
//
