LOCUS       NM_001107297            2086 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus Rho GTPase activating protein 22 (Arhgap22),
            mRNA.
ACCESSION   NM_001107297 XM_001056636 XM_224637
VERSION     NM_001107297.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2086)
  AUTHORS   Valnegri,P., Montrasio,C., Brambilla,D., Ko,J., Passafaro,M. and
            Sala,C.
  TITLE     The X-linked intellectual disability protein IL1RAPL1 regulates
            excitatory synapse formation by binding PTPdelta and RhoGAP2
  JOURNAL   Hum Mol Genet 20 (24), 4797-4809 (2011)
   PUBMED   21926414
REFERENCE   2  (bases 1 to 2086)
  AUTHORS   Kuo,J.C., Han,X., Hsiao,C.T., Yates,J.R. 3rd and Waterman,C.M.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474046.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_224637.4, XM_001056636.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2086
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p16"
     gene            1..2086
                     /gene="Arhgap22"
                     /note="Rho GTPase activating protein 22"
                     /db_xref="GeneID:306279"
                     /db_xref="RGD:1307237"
     exon            1..165
                     /gene="Arhgap22"
                     /inference="alignment:Splign:2.1.0"
     CDS             114..1739
                     /gene="Arhgap22"
                     /codon_start=1
                     /product="rho GTPase-activating protein 22"
                     /protein_id="NP_001100767.1"
                     /db_xref="GeneID:306279"
                     /db_xref="RGD:1307237"
                     /translation="MGLCCCKDWRGHLRAPKGGAAEREKVPANPEALLLMASSQRDME
                     DWVQAIRRVIWAPLGGGIFGQRLEDTVHHERKFGPRLAPLLVEQCVDFIRERGLSEEG
                     LFRMPGQANLVRDLQDSFDCGEKPLFDRFLDEVQAHSDVNKMSVQNLATVFGPNILRP
                     QVEDPVTIMEGTSLVQHLMTVLIRKHGQLFATPSFEEPASPRGTVQGTVEWGSEEVTR
                     DHQGEPGSSGLPTHRTSSLDGPAAAVLSRTSPPRLGSQAGPAATSPGKRMHTLPGWKS
                     SFRQQGSRSESPKGVSSSLEVPIISSGGNWLINGLSSLRSHRRASSGDRLKDTGSAQR
                     LSTYDNVPPSSHLSSTASVASTAWSVASSSREASIGSCTACRASNSSACSSLHTEWAL
                     EPSPLPSSSEGHPSPDLGHSLDEACVGSGSSEPNDPGSPSQAHVRRCRALQGQVAELR
                     AELCHQRIEYQRSLKSIEEGNSDLRKQMCRLEEELDQEKKKYAMLEIKLRNSERARED
                     AERRNQLLQREMEEFFATLGSLTAGTKGARAPE"
     exon            166..294
                     /gene="Arhgap22"
                     /inference="alignment:Splign:2.1.0"
     exon            295..502
                     /gene="Arhgap22"
                     /inference="alignment:Splign:2.1.0"
     exon            503..624
                     /gene="Arhgap22"
                     /inference="alignment:Splign:2.1.0"
     exon            625..1510
                     /gene="Arhgap22"
                     /inference="alignment:Splign:2.1.0"
     exon            1511..2086
                     /gene="Arhgap22"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagtcccgg ttcgccccac gagcccaggg ggctagtgcg ggccagccag gccgctccgg
       61 gggtgtcgac gggggcgggg agcggaggcg agcggccggg gagaggcggt gccatggggc
      121 tgtgctgctg caaggactgg agaggacacc tgcgagcgcc caaaggcggt gccgcagagc
      181 gggagaaggt gccagccaat cctgaggcgc tcctgctcat ggccagctcc cagcgtgata
      241 tggaggactg ggtgcaggcc atccgccgag tcatctgggc cccgctgggc ggagggatct
      301 ttgggcagcg actggaggac acagtgcacc atgagcggaa gtttggtccc cggctggcac
      361 ctctgctggt ggagcagtgt gtggacttca tccgggagcg aggactcagt gaagaggggc
      421 tcttccgtat gcccggccag gccaacctgg tgagggacct gcaggattcc ttcgactgtg
      481 gggagaagcc gctgtttgac aggtttctgg atgaagtgca ggcccactca gacgtcaaca
      541 agatgagcgt ccagaacttg gcaactgtct ttggccctaa catcctccgg ccacaggtgg
      601 aggatccagt caccatcatg gaaggcacat ctttggttca gcatctgatg actgtcctca
      661 tccgaaaaca cggacagctc tttgccacgc cctcctttga agaacctgct tcaccacgtg
      721 gtactgtcca gggcacagta gagtggggct ctgaagaggt caccagagac caccagggcg
      781 agcctgggag ctctggcttg cccacacaca ggacttcctc tctggatggg ccagctgcag
      841 cagtgctctc tagaacttct ccgccacgcc ttggcagcca agccggccct gcggccacca
      901 gccctgggaa gaggatgcat actttgcctg gctggaagtc ttcttttcgg cagcaggggt
      961 cccggtcaga gagcccaaag ggggtcagct catccttaga ggtacccatc atctcctctg
     1021 gtgggaactg gctcataaac gggctatcgt ctcttcgcag ccaccgtcgg gcctcatcag
     1081 gggaccggct taaggataca ggctcagcac agagactctc cacctatgat aacgtgccac
     1141 catccagcca cctttctagc actgccagcg tggccagcac ggcatggtct gtagcctcat
     1201 cctcccgaga ggcctccatc ggcagctgca ctgcctgccg ggccagcaac tcttctgcct
     1261 gcagctcctt acacactgag tgggcactcg agccctctcc tctccccagc agcagtgagg
     1321 gccacccgtc cccggacctg ggccacagct tggatgaggc atgtgtgggc agtggcagca
     1381 gtgagcccaa tgacccgggc agtccctcac aggcccatgt tcgccgctgc cgggctctcc
     1441 agggccaggt ggccgagctc agggcggagc tgtgtcacca gaggattgag taccagagga
     1501 gcctgaaaag catcgaggag ggcaattctg acctgcggaa gcagatgtgt cggttggaag
     1561 aggagctgga ccaggagaag aagaagtatg ccatgctgga gatcaagctt cggaactccg
     1621 agcgagcacg tgaggacgca gagcgcagga accagttgct gcagagggag atggaggagt
     1681 tcttcgccac cctgggaagc ttgactgctg ggaccaaagg ggccagagcc ccagagtgaa
     1741 aggagcggaa gcgcatgtcc acctatgtcc actcactttc cctgcagggc tggccacagg
     1801 ctgcagagga agccgggagc ttcaagtttg ggccaggcca ccagcagggt catctgcctc
     1861 caagtgccag atagagaggg gcctgacgcc agaatgggta ctgtcaggat cccacatagt
     1921 ccaggcagga tctggatact tctccacaca tacgggtccc aggaggtgtc aggggcgatg
     1981 gtgccaagat catgagcatc agcctctcct ccaggaagag tcagtcccca gtggccacct
     2041 ggagagccag gccaccgcca agaactatta aatgtgctct gaaagc
//
