LOCUS       XM_017589037            2450 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus Rho GTPase activating protein 18
            (Arhgap18), transcript variant X1, mRNA.
ACCESSION   XM_017589037
VERSION     XM_017589037.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017589037.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017589037.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2450
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2450
                     /gene="Arhgap18"
                     /note="Rho GTPase activating protein 18; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 31 ESTs, 1 long SRA read, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     16 samples with support for all annotated introns"
                     /db_xref="GeneID:293947"
                     /db_xref="RGD:1305053"
     CDS             266..2230
                     /gene="Arhgap18"
                     /codon_start=1
                     /product="rho GTPase-activating protein 18 isoform X1"
                     /protein_id="XP_017444526.1"
                     /db_xref="GeneID:293947"
                     /db_xref="RGD:1305053"
                     /translation="MFSRSPALELRKIFTGVTRLGHCFLCSRRYGQYTMNPESSTKLS
                     ERPPFDRSSSQDSLDEVSMEAYWTELENIKRSTENCQEGQEAIVVKEPDEGELEEEWL
                     KEAGLSNLFGESADDSQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKSKQYHIPDVR
                     DIFAQQREAQEKSPDDSDLRSVRTNENEDQGKDDQPSSGAVDNKEPIPRVPEDIPASE
                     TDINLEVSFAEQAVNQKELSKERMQKTRGNDASLPSFRLPKDKTGTTRIGDLAPQDMK
                     KVCYLSLIELTALYDVLGVELKQQKAVKIKTRDSGLFGIPLTILLEQDQRKVPGTRIP
                     LIFQKLISCIEEGSLETEGLLRIPGAAMRVKNLCQELEAKFYEGTFNWESVKQHDAAS
                     LLKLFLRELPQPLLSTEYLKAFQAVQNLPTKKEQLQALNLLVILLPDANRDTLKALLE
                     FLQRVIDNKEKNKMTAVNVAMVMAPNLFMCHALGLKSSEHREFEMAAGTANTMHLLIR
                     YQKLLWTIPKFIVNQVRKHNTAHQKKERRAMKKLLKKMAYDREKHEKQDRAANGADVP
                     QGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQESGVAQTLKKGEVFLYEIGGNI
                     GERCLDDDTYMKDLYHLNPNAEWVIKSKPV"
ORIGIN      
        1 gctctggatc tgggcagcgg cagcagcagc agctgagcag ccaggggtcg cgggcatgca
       61 ccagctgaaa cttgtgcagg ctgagtgcta acaagtcgtc ctcttctggt gcccacacgt
      121 ccgcacagcc ctttacacag ctgccctgat gatggagcat aaattacaag ctccggatcc
      181 tggctcaccg gagggagccg gtgggaggca cagagaaggg gtatagcatt tggaggaaag
      241 cgactctcac ggagctctct tgagcatgtt ttctcggtct cctgctctgg aactgaggaa
      301 gatatttaca ggagtgacta ggcttggcca ctgctttctc tgcagtcgca gatatggcca
      361 gtacaccatg aacccagaaa gctccaccaa actttcagag agacctccat tcgatcgatc
      421 aagttctcag gattctttgg atgaagtgtc aatggaagcc tattggacag aactagaaaa
      481 catcaagagg tctactgaaa actgccaaga aggtcaagaa gccatagttg tcaaagaacc
      541 tgatgaggga gaactggaag aagaatggct caaggaggca ggtctgtcca atcttttcgg
      601 ggagtccgcc gatgactctc aggagagcat cgtgtttttg tctacgctga cccggactca
      661 ggcagcagct gtccagaaac gggtagaaac ggtctcccaa accctgagga agaaaagcaa
      721 acagtaccac attcctgacg tcagagacat atttgctcaa cagagagagg cacaagaaaa
      781 atctccagat gactcagact tgcggtcagt cagaacaaat gaaaacgaag accaaggaaa
      841 agatgaccag ccatctagtg gggctgtgga taacaaggag ccgatcccac gggtgcctga
      901 ggatatacct gcctctgaaa cagacatcaa tctggaggtg tcctttgcgg aacaagctgt
      961 caatcagaaa gagctcagta aggagaggat gcagaagacg agaggaaacg atgcctcttt
     1021 acccagtttc agactgccta aagataaaac aggtacaaca aggattggag acttggcacc
     1081 tcaagacatg aagaaagttt gctatctatc cctgatcgaa ctcactgccc tatatgatgt
     1141 attgggtgtg gagctcaaac aacagaaagc tgtgaaaatc aaaaccagag actctggtct
     1201 ttttggtatt cctttaacta tattgttaga acaagatcaa agaaaagtgc ctggaacgcg
     1261 aatacccttg atctttcaaa aactgatttc ttgcattgaa gaaggcagtc tggaaactga
     1321 gggcctcctg cggataccag gagcagccat gagagtcaag aatctttgcc aagaattaga
     1381 agcaaagttt tatgaaggaa ctttcaactg ggaaagtgtc aagcagcacg atgcggccag
     1441 cctgctgaag ctctttctga gagaactgcc ccagcctctg ctgagcacgg agtacctcaa
     1501 agccttccag gctgttcaga atcttccaac caaaaaggaa caattgcagg ctttgaacct
     1561 ccttgtcatt cttctacctg acgcaaacag agacacactg aaggccttgc tagaatttct
     1621 ccaaagagtc atcgataaca aagagaaaaa caagatgaca gccgtgaatg tagcaatggt
     1681 catggccccg aatctcttca tgtgccatgc actgggcttg aagtccagtg aacaccgaga
     1741 atttgaaatg gcagcaggga cagcaaatac catgcactta ttgattcggt accagaaact
     1801 tctgtggaca atccctaaat ttattgtgaa ccaagtgagg aagcacaata ctgcgcatca
     1861 gaagaaggaa aggagagcca tgaagaaatt gctgaagaaa atggcgtatg accgggaaaa
     1921 acacgaaaag caagacagag ctgcaaatgg tgctgacgtt cctcagggag tgattcgagt
     1981 gcaagctccc catctttcaa aagtttccat ggcaatacag ctaactgaag aactaaaagc
     2041 cagcgacgta cttgccaggt ttctgagcca agaaagtggg gttgcccaga cactcaagaa
     2101 aggagaagtt ttcctgtatg agattggagg aaatattggg gaacgttgcc ttgatgacga
     2161 tacatacatg aaggacttgt accatctgaa cccaaatgct gaatgggtca taaaatcaaa
     2221 gccagtgtag atgactaccc cgaggccatg tcatcattct tgctggatca agagtgtaaa
     2281 taaaagcaac aggtttctta actattcagc cgtacccaat tattacaaag tgacaccctc
     2341 aagccttaaa attatagatt ttttttgtgg cttccacagt tgttaattat tattattatt
     2401 ttagaaaatg agtatttttg gagcataatt aaatgacttt ttctaaacaa
//
