LOCUS       NM_001109501            2618 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus Rho GTPase activating protein 10 (Arhgap10),
            mRNA.
ACCESSION   NM_001109501 XM_001065757 XM_001065808 XM_001065859 XM_001065920
VERSION     NM_001109501.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2618)
  AUTHORS   Koeppel MA, McCarthy CC, Moertl E and Jakobi R.
  TITLE     Identification and characterization of PS-GAP as a novel regulator
            of caspase-activated PAK-2
  JOURNAL   J Biol Chem 279 (51), 53653-53664 (2004)
   PUBMED   15471851
REFERENCE   2  (bases 1 to 2618)
  AUTHORS   Ren XR, Du QS, Huang YZ, Ao SZ, Mei L and Xiong WC.
  TITLE     Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2
            interacting with PSGAP, a novel pleckstrin homology and Src
            homology 3 domain containing rhoGAP protein
  JOURNAL   J Cell Biol 152 (5), 971-984 (2001)
   PUBMED   11238453
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473972.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001065920.1, XM_001065859.1, XM_001065808.1, XM_001065757.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132275,
                              SAMD00132291 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2618
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q11"
     gene            1..2618
                     /gene="Arhgap10"
                     /note="Rho GTPase activating protein 10"
                     /db_xref="GeneID:688429"
                     /db_xref="RGD:1588859"
     exon            1..344
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     CDS             191..2551
                     /gene="Arhgap10"
                     /codon_start=1
                     /product="rho GTPase-activating protein 10"
                     /protein_id="NP_001102971.1"
                     /db_xref="GeneID:688429"
                     /db_xref="RGD:1588859"
                     /translation="MGLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGK
                     NLIAATKSLSAAQRKFAHSLRDFKFEFIGDAETDDERCIDASLREFSNFLKNLEEQRE
                     IMALSVTETLIKPLEKFRKEQLGAVKEEKKKFDKETERNYSLIDKHLTLSARKKDTHL
                     QEADLQVEQNRQHFYELSLEYVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHELS
                     KDFNHYKTELQINIQNTRNRFEGTRSEVEELMNKIRQNPKDQKRASQFTAEGYLYVQE
                     KRPAPFGSSWVKHYCMYRKTAKKFNMIPFEHRSGGKLGDGEAFFLKECTKRHIDSTDR
                     RFCFDIEAADRPGVPLTVQAFSEEERKQWLEALGGKEALFHTFNRAIVPRPEGGAQLD
                     KMGFTILRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNELDLENSTDW
                     EVKTVTSALKQYLRSLPEPLMTYELHRDFIVPAKSGSPESRVSAIHFLVHKLPEKNKE
                     MLDILVKHLTNVSSHSKQNLMTVANLGVVFGPTLMRPQEETVAAIMDLKFQNIVVEIL
                     IENHEKIFRTSPDTTFAEPTCLSASPPNAPPRQSKRQGQRTKRPVAVYNLCLELEEGD
                     SPSPLKEDPPSSSQDSLSTPSPTTSAAHGPPGPDGNHLAADRGNCGDATATTPSQTRP
                     SMVQWLNMQSPTTPSSNPAGTPPSPRMSPFPLSPAASIVDKLPECLINRKARAVYPCE
                     AEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL"
     exon            345..440
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            441..502
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            503..574
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            575..676
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            677..787
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            788..892
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1022
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1129
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1224
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..1306
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            1307..1352
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            1353..1418
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            1419..1493
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1581
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..1640
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            1641..1746
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            1747..1906
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            1907..2057
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            2058..2217
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            2218..2370
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            2371..2462
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
     exon            2463..2618
                     /gene="Arhgap10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagtcgcgc cgcgtactcg cctaggtcgc tgggctcggc gggacatgac cgcgctgtgc
       61 tcgccttgcg ctcagccctg ctagcagctc gtcgctgctc gccgccgccg ccgccgccac
      121 ctcctctctc cgtacctggc caccgccccc gagcccagct cggcctgcgc ccgcgcgcac
      181 cgctgtagtc atggggctgc agcccctgga gttcagcgat tgctacctcg acagcccgtg
      241 gttccgggag aggatccgcg ctcacgaagc ggagctcgag aggaccaaca agttcatcaa
      301 agagctcatc aaagacggca agaaccttat cgctgccacc aaaagtctgt cagctgccca
      361 gcggaagttt gctcactctc tcagagactt caagtttgag tttatcgggg atgctgagac
      421 tgatgatgaa cggtgcatag atgcctcctt acgggaattt tctaactttc tgaagaatct
      481 ggaagaacag agagaaatca tggcattaag tgtgactgaa accctgatta agcccttgga
      541 gaaattcaga aaagagcaac ttggagctgt aaaggaagaa aaaaagaagt ttgacaaaga
      601 gacggaaagg aattacagtc taatcgataa gcacttgacc ctgtctgcca ggaagaagga
      661 cacgcacttg caggaggctg acctccaagt ggaacagaac cggcagcatt tctacgagct
      721 ctctcttgaa tacgtgtgta agctccagga aatccaggaa aggaagaagt tcgagttcgt
      781 ggagccgatg ctgtcctttt ttcagggaat gttcactttc tatcatcaag gtcacgagct
      841 ttccaaagac ttcaaccact acaagacaga actacagatc aacattcaga atacacggaa
      901 tcgatttgag ggaaccaggt cggaagtgga ggaacttatg aataaaatta gacaaaaccc
      961 caaggaccag aagcgagcca gccagttcac agcagaaggg tacctgtacg tccaggaaaa
     1021 aagacctgct ccatttgggt ccagttgggt caaacactac tgcatgtacc ggaaaacagc
     1081 caagaaattc aacatgattc cctttgagca cagatctggg gggaaactgg gggatggaga
     1141 ggcgttcttt ttgaaagaat gcaccaaaag gcatattgac tccactgaca gaaggttttg
     1201 ctttgacatc gaagccgccg acaggcctgg cgtccccttg accgtgcagg cgttttcaga
     1261 agaggaaagg aagcagtggt tggaagctct gggtggaaaa gaagctttgt tccacacttt
     1321 taatagagcc atcgtcccaa gaccagaagg aggtgcacag ttggataaga tgggattcac
     1381 aattctcaga aagtgcatca gtgctgttga gacacgaggt ataaatgacc aaggactgta
     1441 cagagttgtg ggggtgagtt caaaggtcca gagacttctg agtatgttga tggatgtaaa
     1501 aacgtgcaat gagctggacc tggagaattc cacagattgg gaggtgaaga cagtaacaag
     1561 tgccttgaag cagtatctga ggagtcttcc agagcctctc atgacctatg agttacatag
     1621 agacttcatt gttccggcca aaagtggcag cccagaatcc cgtgtcagtg ccatccactt
     1681 cttggtacac aaactgccag agaagaataa ggagatgctg gatatcttgg tgaagcacct
     1741 aaccaatgtg tcaagtcact cgaagcagaa tctaatgaca gtggcgaatt taggagtggt
     1801 atttggaccc actctgatga gaccacagga agagactgtt gcggccatta tggacttgaa
     1861 gtttcaaaat atcgtcgtag aaatcttaat cgaaaaccac gaaaagattt ttcggacctc
     1921 gcctgatacc acatttgctg agcccacatg cctgtcagcg tcacccccaa acgctccacc
     1981 acgacagtcc aagagacaag ggcagaggac gaagagacca gtggctgtgt acaacctttg
     2041 tcttgaactg gaggagggtg atagtcccag ccctctcaag gaggatcccc ccagcagcag
     2101 tcaggattca ctgtccactc cgtctcctac aacttcagct gcccatgggc ctccgggacc
     2161 agacggaaac caccttgcag cagacagagg gaactgtgga gacgccactg ccactacgcc
     2221 aagccagacc cggccatcca tggtgcagtg gctgaatatg cagtctccca ccacaccaag
     2281 ctccaaccca gctgggacac ctccttcacc caggatgtca ccattccccc tctctcctgc
     2341 tgcctccatt gtagacaagc tgcctgaatg ccttatcaac cgcaaggccc gtgcagtgta
     2401 cccgtgtgag gcagagcata gctcggaatt gtcatttgaa ataggagcca tttttgagga
     2461 tgttcagacc tcaagggaac ccggatggct ggaagggacc ctgaacggca agcgagggct
     2521 gattccacag aattacgtca agctactgta gtccctggcc atgggggctc ctgctgatcc
     2581 tagcacccca agcaccagcc tggaaatggc acccaaat
//
