LOCUS       NM_021763               1713 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus ARF interacting protein 1 (Arfip1), mRNA.
ACCESSION   NM_021763
VERSION     NM_021763.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1713)
  AUTHORS   Huang,L.H., Lee,W.C., You,S.T., Cheng,C.C. and Yu,C.J.
  TITLE     Arfaptin-1 negatively regulates Arl1-mediated retrograde transport
  JOURNAL   PLoS One 10 (3), e0118743 (2015)
   PUBMED   25789876
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1713)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1713)
  AUTHORS   Cruz-Garcia,D., Ortega-Bellido,M., Scarpa,M., Villeneuve,J.,
            Jovic,M., Porzner,M., Balla,T., Seufferlein,T. and Malhotra,V.
  TITLE     Recruitment of arfaptins to the trans-Golgi network by PI(4)P and
            their involvement in cargo export
  JOURNAL   EMBO J 32 (12), 1717-1729 (2013)
   PUBMED   23695357
REFERENCE   4  (bases 1 to 1713)
  AUTHORS   Gehart,H., Goginashvili,A., Beck,R., Morvan,J., Erbs,E.,
            Formentini,I., De Matteis,M.A., Schwab,Y., Wieland,F.T. and
            Ricci,R.
  TITLE     The BAR domain protein Arfaptin-1 controls secretory granule
            biogenesis at the trans-Golgi network
  JOURNAL   Dev Cell 23 (4), 756-768 (2012)
   PUBMED   22981988
  REMARK    GeneRIF: The protein kinase D (PKD) phosphorylates Arfaptin-1 at
            serine 132, which disrupts the ability of Arfaptin-1 to inhibit the
            activity of ADP ribosylation factor, an important component of the
            vesicle scission machinery.
REFERENCE   5  (bases 1 to 1713)
  AUTHORS   Ho,W.T., Exton,J.H. and Williger,B.T.
  TITLE     Arfaptin 1 inhibits ADP-ribosylation factor-dependent matrix
            metalloproteinase-9 secretion induced by phorbol ester in HT 1080
            fibrosarcoma cells
  JOURNAL   FEBS Lett 537 (1-3), 91-95 (2003)
   PUBMED   12606037
REFERENCE   6  (bases 1 to 1713)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
REFERENCE   7  (bases 1 to 1713)
  AUTHORS   Kanoh,H., Williger,B.T. and Exton,J.H.
  TITLE     Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation
            factor, is recruited to Golgi membranes
  JOURNAL   J Biol Chem 272 (9), 5421-5429 (1997)
   PUBMED   9038142
REFERENCE   8  (bases 1 to 1713)
  AUTHORS   Mesa,K., Gebelein,B., Cook,T. and Urrutia,R.
  TITLE     Identification and characterization of zinc finger encoding genes
            from the tumoral exocrine pancreatic cell line AR42J
  JOURNAL   Cancer Lett 103 (2), 143-149 (1996)
   PUBMED   8635150
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 26, 2020 this sequence version replaced NM_021763.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY004875.1, SRR26643295.9435.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-75                JAXUCZ010000002.1  172221091-172221165 c
            76-177              JAXUCZ010000002.1  172193826-172193927 c
            178-286             JAXUCZ010000002.1  172180719-172180827 c
            287-361             JAXUCZ010000002.1  172174399-172174473 c
            362-474             JAXUCZ010000002.1  172172933-172173045 c
            475-696             JAXUCZ010000002.1  172167894-172168115 c
            697-854             JAXUCZ010000002.1  172164157-172164314 c
            855-1029            JAXUCZ010000002.1  172158852-172159026 c
            1030-1713           JAXUCZ010000002.1  172142942-172143625 c
FEATURES             Location/Qualifiers
     source          1..1713
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1713
                     /gene="Arfip1"
                     /note="ARF interacting protein 1"
                     /db_xref="GeneID:60382"
                     /db_xref="RGD:708401"
     exon            1..75
                     /gene="Arfip1"
                     /inference="alignment:Splign:2.1.0"
     exon            76..177
                     /gene="Arfip1"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..1185
                     /gene="Arfip1"
                     /note="ADP-ribosylation factor interacting protein 1"
                     /codon_start=1
                     /product="arfaptin-1"
                     /protein_id="NP_068531.1"
                     /db_xref="GeneID:60382"
                     /db_xref="RGD:708401"
                     /translation="MAEESPKNSAAEIPVTSNGEVGDAHEHGYNRDLKHSLPSGLGLS
                     ETQITSHGFDSTKEGVTEAGASQGSSAPPLPCVLSPSRVAASQLTQHAGGQRTHTKGG
                     PVILADEIKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRD
                     NKKKYENILKLAQTLSTQLFQMVHTQKQLGDAFADLSLKSLELHEEFGYNADTQKLLA
                     KNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYENARIEYDAYRTDLEELNLGPRD
                     ANTLPKIEQSQHLFQIHKEKYDKMRSDVSVKLKFLEENKVKVLRNQLALFHSAVAAYF
                     AGNQKQLEQTLKQFHVKLKTPGVDAPSWLEEQ"
     exon            178..286
                     /gene="Arfip1"
                     /inference="alignment:Splign:2.1.0"
     exon            287..361
                     /gene="Arfip1"
                     /inference="alignment:Splign:2.1.0"
     exon            362..474
                     /gene="Arfip1"
                     /inference="alignment:Splign:2.1.0"
     exon            475..696
                     /gene="Arfip1"
                     /inference="alignment:Splign:2.1.0"
     exon            697..854
                     /gene="Arfip1"
                     /inference="alignment:Splign:2.1.0"
     exon            855..1029
                     /gene="Arfip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1713
                     /gene="Arfip1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacgcgattc ccgagagctg ctgcaaccgg gagaacccgc gacggagcgc tgccggcttc
       61 cctgctgaca gacaggtgtc tgccatggct gaagaatctc ccaaaaattc tgcagcggaa
      121 attccagtaa ctagtaatgg ggaagttggt gatgcccacg aacatggcta taatagggat
      181 ttgaagcatt cattaccatc tggacttgga ctctcagaaa ctcaaattac atctcatggc
      241 tttgacagta ccaaagaggg ggttactgaa gcaggagcat cccaaggttc ctcagcacca
      301 cctttgccat gtgttctgtc tcccagcagg gtggcagcta gtcagctgac ccagcacgca
      361 ggtggccaaa gaacacacac aaaaggtgga ccagttattt tagcagatga aattaaaaat
      421 cctgcaatgg agaagttaga acttgttaga aaatggagtc tcaacacata taagtgtact
      481 cggcaaatta tatctgagaa actaggccgt ggctcaagaa ccgtggacct tgaacttgaa
      541 gctcagattg acatattaag agataataag aaaaaatatg aaaacattct gaaactggct
      601 cagaccttgt cgacgcagct tttccagatg gtacataccc aaaagcaact tggagatgca
      661 tttgctgacc tgagtttgaa gtctctagaa ctccacgaag aatttggcta taatgcagat
      721 acacagaagc tgctggctaa aaatggagag actcttcttg gggccattaa ttttttcatt
      781 gctagcgtga acaccttggt gaataaaaca attgaagaca cactaatgac agtaaaacag
      841 tacgagaacg ccagaattga atatgatgca tatcgcactg atttggaaga actgaacctt
      901 ggacctcgtg atgcaaacac tctgccaaaa attgagcagt cacagcatct gttccaaata
      961 cacaaggaaa aatatgacaa aatgcgcagt gatgtttctg tcaaattgaa atttcttgag
     1021 gaaaataagg ttaaggtgtt acgcaatcaa ctggcccttt tccacagtgc tgttgctgcc
     1081 tactttgctg ggaatcagaa gcagcttgaa cagactctca agcagttcca tgtcaaattg
     1141 aaaaccccag gagtggatgc cccgtcttgg cttgaagaac agtaaactca ccaggaaaga
     1201 aggacagtgt attgttaaac aactaataaa ctagtaagag tgaagtaatg tgggaggtgt
     1261 gaggtgacca ccatcgtagt ggctcctgca cagatagctt ttaatttccc ttttcatacc
     1321 gtaacaattg agctgttaaa tttgatggga aggtaggtga tttttatgta aacataattt
     1381 ctataattct aaacataata atcttccttt ttgagaaatc ctttttgtac tgtgagggtt
     1441 gatggctatt tctgtagttt gaaatattta atatagattt gcactgacaa gataaaagtt
     1501 caaggctttt tgggtcccag aaatgagggc cagctatagt tttccaaggg aggtttacat
     1561 gatttgtatc agtgtcagat attttatata tgaatatatt caacatcttt aagaagttca
     1621 tgtttgtgta ttatctttta aaaaaagaag ctattttgca gagtaagttt tatggtgtcc
     1681 tgcagtctca ccccagggac agcttgaata aat
//
