LOCUS       NM_001414037            2042 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus ARF GTPase 1 (Arf1), transcript variant 2, mRNA.
ACCESSION   NM_001414037 XM_039086790
VERSION     NM_001414037.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2042)
  AUTHORS   Hansen,M.D., Johnsen,I.B., Stiberg,K.A., Sherstova,T., Wakita,T.,
            Richard,G.M., Kandasamy,R.K., Meurs,E.F. and Anthonsen,M.W.
  TITLE     Hepatitis C virus triggers Golgi fragmentation and autophagy
            through the immunity-related GTPase M
  JOURNAL   Proc Natl Acad Sci U S A 114 (17), E3462-E3471 (2017)
   PUBMED   28389568
REFERENCE   2  (bases 1 to 2042)
  AUTHORS   Rodrigues,F.F., Shao,W. and Harris,T.J.
  TITLE     The Arf GAP Asap promotes Arf1 function at the Golgi for cleavage
            furrow biosynthesis in Drosophila
  JOURNAL   Mol Biol Cell 27 (20), 3143-3155 (2016)
   PUBMED   27535433
REFERENCE   3  (bases 1 to 2042)
  AUTHORS   Rocca,D.L., Amici,M., Antoniou,A., Blanco Suarez,E., Halemani,N.,
            Murk,K., McGarvey,J., Jaafari,N., Mellor,J.R., Collingridge,G.L.
            and Hanley,J.G.
  TITLE     The small GTPase Arf1 modulates Arp2/3-mediated actin
            polymerization via PICK1 to regulate synaptic plasticity
  JOURNAL   Neuron 79 (2), 293-307 (2013)
   PUBMED   23889934
  REMARK    GeneRIF: Arf1 is a critical regulator of actin dynamics and
            synaptic function via modulation of PICK1.
REFERENCE   4  (bases 1 to 2042)
  AUTHORS   Mazaki,Y., Nishimura,Y. and Sabe,H.
  TITLE     GBF1 bears a novel phosphatidylinositol-phosphate binding module,
            BP3K, to link PI3Kgamma activity with Arf1 activation involved in
            GPCR-mediated neutrophil chemotaxis and superoxide production
  JOURNAL   Mol Biol Cell 23 (13), 2457-2467 (2012)
   PUBMED   22573891
REFERENCE   5  (bases 1 to 2042)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   6  (bases 1 to 2042)
  AUTHORS   Greasley,S.E., Jhoti,H., Teahan,C., Solari,R., Fensome,A.,
            Thomas,G.M., Cockcroft,S. and Bax,B.
  TITLE     The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to
            GDP determined from two different crystal forms
  JOURNAL   Nat Struct Biol 2 (9), 797-806 (1995)
   PUBMED   7552752
REFERENCE   7  (bases 1 to 2042)
  AUTHORS   Makler,V., Cukierman,E., Rotman,M., Admon,A. and Cassel,D.
  TITLE     ADP-ribosylation factor-directed GTPase-activating protein.
            Purification and partial characterization
  JOURNAL   J Biol Chem 270 (10), 5232-5237 (1995)
   PUBMED   7890632
REFERENCE   8  (bases 1 to 2042)
  AUTHORS   Massenburg,D., Han,J.S., Liyanage,M., Patton,W.A., Rhee,S.G.,
            Moss,J. and Vaughan,M.
  TITLE     Activation of rat brain phospholipase D by ADP-ribosylation factors
            1,5, and 6: separation of ADP-ribosylation factor-dependent and
            oleate-dependent enzymes
  JOURNAL   Proc Natl Acad Sci U S A 91 (24), 11718-11722 (1994)
   PUBMED   7972129
REFERENCE   9  (bases 1 to 2042)
  AUTHORS   Zhang,C.J., Rosenwald,A.G., Willingham,M.C., Skuntz,S., Clark,J.
            and Kahn,R.A.
  TITLE     Expression of a dominant allele of human ARF1 inhibits membrane
            traffic in vivo
  JOURNAL   J Cell Biol 124 (3), 289-300 (1994)
   PUBMED   8294513
REFERENCE   10 (bases 1 to 2042)
  AUTHORS   Tsai,S.C., Adamik,R., Haun,R.S., Moss,J. and Vaughan,M.
  TITLE     Effects of brefeldin A and accessory proteins on association of
            ADP-ribosylation factors 1, 3, and 5 with Golgi
  JOURNAL   J Biol Chem 268 (15), 10820-10825 (1993)
   PUBMED   8496147
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 15, 2022 this sequence version replaced XM_039086790.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.60786.1,
                                           SRR26643285.42657.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840106, SAMN12840107
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-336               JAXUCZ010000010.1  44513659-44513994   c
            337-520             JAXUCZ010000010.1  44499456-44499639   c
            521-631             JAXUCZ010000010.1  44499265-44499375   c
            632-756             JAXUCZ010000010.1  44498954-44499078   c
            757-2042            JAXUCZ010000010.1  44497543-44498828   c
FEATURES             Location/Qualifiers
     source          1..2042
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..2042
                     /gene="Arf1"
                     /note="ARF GTPase 1"
                     /db_xref="GeneID:64310"
                     /db_xref="RGD:621270"
     exon            1..336
                     /gene="Arf1"
                     /inference="alignment:Splign:2.1.0"
     exon            337..520
                     /gene="Arf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             373..918
                     /gene="Arf1"
                     /EC_number="3.6.5.2"
                     /codon_start=1
                     /product="ADP-ribosylation factor 1"
                     /protein_id="NP_001400966.1"
                     /db_xref="GeneID:64310"
                     /db_xref="RGD:621270"
                     /translation="MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVT
                     TIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNE
                     AREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCA
                     TSGDGLYEGLDWLSNQLRNQK"
     exon            521..631
                     /gene="Arf1"
                     /inference="alignment:Splign:2.1.0"
     exon            632..756
                     /gene="Arf1"
                     /inference="alignment:Splign:2.1.0"
     exon            757..2042
                     /gene="Arf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgggagcga aaccaacgcc tggctgggag cagccgccgc ggaggtgaga agcggggctc
       61 tctgaggccg aagctgggga ggccacgggc tggtcatcgt gggaatcgcg gggctctcgg
      121 ctgcggctgc taaggaccga gtctggtcgg gcggcctgag gtctgtgctc agtgggctcg
      181 gcggcaggcc ggacagaaga tcagggcgcc cccaagtccc gcgtcgccca cggccgcttg
      241 gccctccccc actccgcggc ccttacgcca ggccgcccgc cgcgggccgc agcccggaag
      301 tccggccagg acgccggctc ttctccagga agccaggtct ctggccagta tcgcttccac
      361 ctgtccacaa acatggggaa tatctttgca aacctcttca agggcctttt tggcaaaaaa
      421 gaaatgcgca ttctcatggt gggcctggat gctgcaggga agacaacaat tctatacaaa
      481 ctgaagctgg gcgaaattgt gaccaccatt cccaccattg gtttcaacgt ggagactgtt
      541 gaatacaaga atatcagctt caccgtgtgg gatgtgggtg gccaggacaa gattcggccg
      601 ctgtggcgcc actacttcca gaacacccaa ggcttgatct tcgtagtgga cagcaatgac
      661 agagagcgtg tgaacgaggc ccgtgaagag cttatgagga tgctagctga agatgagctc
      721 cgagatgccg ttctcttggt gtttgccaac aagcaggacc tccccaatgc catgaatgcg
      781 gccgaaatca cagacaagct ggggctgcac tctctacgcc acaggaactg gtacattcag
      841 gctacctgtg ccaccagcgg agacgggctc tatgaaggac tagattggct gtctaatcag
      901 ctccggaacc agaagtgaac cagacccctc cttccccctc acttcctctt ctccgccctc
      961 agctttcctc tcatgtggca aacgtgcgac tctgtggtcc tgagtgccag aagctgtctc
     1021 catgggttgg tcacagtgtg catcgcaccg tgctgtacat gtgcagacgc agcctgcagc
     1081 caggttttta tttaatgtaa atagtttctg tttccactga ggcagtttct ggtactccta
     1141 tgcaatatta cttagctttt ttattgtaaa aagagaatca actcactgtc agtactgaga
     1201 agggatttgg gtgtaggggc acctggcctc cgggagccat tgggctgtag actggtgtcg
     1261 gtatccattt ggtggttggt ttttaaccca aactcagtgc attttttaaa aatagtttaa
     1321 aacacaggac aagaacactt gaacacacag aacggagact atgcctagtg taggttttgc
     1381 agttaatggc ctgaatgcta gttatcagat cacctgtttc cctgtgggga caggagagaa
     1441 ggtgacgaac aaaccaccat ccgctgcatg gtcacagtag agcccccgtg actcgcctgt
     1501 ctttgggtca cctgcattcc atagcattgt gcttgtactt gtgctcacat ggtcacctag
     1561 gggtaggctg ggagccattg tggggtgcag ggcctggctt gtacttggtg tgtggccagg
     1621 cccaatggca gcctacatac ccagcttact cttgggccca cttggacgca ctggcaggag
     1681 gcctgggtct caccagcagg agtgcgtgca aggtgggagg gtcggtccat tacagaccca
     1741 catcctggag cacccccatc tccatgtgtg aagtagcttc ctccctcagc ctgcaagggt
     1801 ccgatttgcc atcgaaagac gacctctact tttttctttt gtattttgat aaacactgaa
     1861 gaagctggag ctgttaaatt tatcttgggg aaatctcaga actggtttat ttggtgtcgt
     1921 ggaacctctt actgctttca atacacaatt agtaatcaac tgttttgtat acttgttttc
     1981 agttttcatt tcgacaagca ctgtaattat agctattaga ataaagtctc ttaactattt
     2041 ga
//
