LOCUS       XM_039097402            7129 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ArfGAP with RhoGAP domain, ankyrin
            repeat and PH domain 3 (Arap3), transcript variant X1, mRNA.
ACCESSION   XM_039097402
VERSION     XM_039097402.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051353.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039097402.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7129
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..7129
                     /gene="Arap3"
                     /note="ArfGAP with RhoGAP domain, ankyrin repeat and PH
                     domain 3; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 25 ESTs, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 55 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:361314"
                     /db_xref="RGD:1304938"
     CDS             654..5270
                     /gene="Arap3"
                     /codon_start=1
                     /product="arf-GAP with Rho-GAP domain, ANK repeat and PH
                     domain-containing protein 3 isoform X1"
                     /protein_id="XP_038953330.1"
                     /db_xref="GeneID:361314"
                     /db_xref="RGD:1304938"
                     /translation="MAAPQDLDIAVWLAAVHLEQYADTFRRHGLATAGAAQRLGHEEL
                     RHLGISATGHRKRILRLLQSGSAEGFLDSQLDSTMEPTPSPAPDAQPSKPVPKPRTVF
                     GLSNPANAQKPGLNPIFWNPEVSRNSECTQRSPPVLPSSSEQPSALNTMEMMPNAIYF
                     GLDLRGRAQAAQDLTPDSSQATVPTPAFRPTTGTVHIMDPGCLYYGVQPVGVPGVPDR
                     RDGRGVCQERAEHSRQDQETREDAGYASLELPGDSILSLPTQDAETSDDLISPYASFS
                     STADRPVPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIE
                     MTRSSKDNKFQVITGQRVFVFRTESEAQRDIWCSTLQSCLKEQRLLGHPRPPHPPRPL
                     RTGMLELRGHKAKVFAALIPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDL
                     LTPHRCFSFTAESGGARQSWAVALQEAVTETLSDYEVAEKVWSNPANRHCADCRASRP
                     DWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWTNEIVQLFIVLGNDRANCF
                     WAGALPPGEGLHPDAAPGPRGEFISRKYKLGLYRKPHPRHPDHSQLLQALCAAMVGPN
                     LLKNMTQLLCVEASEGEEPLSPSALNGSLLSLLPSDSSPGVYNEVVVPATYRGFLYCG
                     PISNKAGAPPLRRGRDAPPRLWCVLGAALEMFASESSSEPLSLLQPQDVVCLGISPPP
                     ADSGDLDRFPFSFELILTGGRIQHFATDGADSLEAWISAVGKWFSPLSCHQLLGPGLL
                     RMGRLWLRSPSHAGLAPGLWLSGFGLLRGDHLFLCPAPGPGPPAPEDMVHLRRLQEIS
                     VVSAADTPDKKEHLVLVETGRTLYLQGEGRLDFAAWNTAIGGAAGGGGTGLQEQQMSR
                     GDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPREHFVE
                     DVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKEVISCLPRVNRRTLA
                     TLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGRGEHEVRVLQELIDGYISVFDI
                     DSDQAAQIDLEVSLITTWKDVQLSQAGDLIMEVYIEQQLPDNCVTLKVSPTLTAEELT
                     NQVLEMRGAASGTDLWVTFEILDHGELERPLHPKEKVLEQALQWCQLPEPCSASLLLR
                     KVSMAHAGCLFTGVRRESPRVGLLRCREEPPRLLGSRFQERFFLVRGRCLLLLKEKKS
                     SKPEREWSLEGAKVYLGIRKKLKPPTLWGFTLILEKMHLCLSCTDEEEMWDWTTSILK
                     AQHDDQQSVVLRRHSSSDLARQKFGTMPLLPIRGDDSGATLLSANQTLRRLHNRRTLS
                     MFFPMKSSQGSVEEQDELEEPVYEEPVYEEVGAFPELTKDMTSTWEWSTKSDTPLTSQ
                     RSFDQTPLTKASMLVQEERIPEPPPGPPSKSSPQARGSLEEQLLQELNNLILRKGEPA
                     TCPESPSQPTSPQSPSPTSLPTQTPSLPTQIPCASNPPSSQPLT"
ORIGIN      
        1 ctggaactct tgcaaatgcc acagggaggg gagagaagca ccgtcccacg gcccaccctg
       61 ctccagcacg tgtaaggtgg gaaagtcgaa aacaaaggtt tttcccaagc atgaaagggt
      121 ccaagcatgt ttggtcaccg tgagaaaggc agactcaatt tggaaaactc aagaaaagaa
      181 tcctaggctg ggaacttggg gcaacagaag ctggtgagcc ttctccagcg ggcttcagca
      241 cagaggcttc agcacagagg ggaggggcct cagcacagag gagtcttcag ctttacccat
      301 tctgttctca tctcccattt aactggatac ttgagtccag cggtcgcggg agaggagctc
      361 agaaggcttc aggccctaca ccttcttccc cttggcagaa cccggtgcaa agaaagctga
      421 gtctaggctc cggataagca aaggcggttg ggtaaggggc ccaaaccacc tgaaggcggg
      481 cacttgcaca aggagcagcg agccatccag ccgtcggggc ggagccgggc tgtggggggt
      541 gggggagggc tgcggggagg cggtgctgac acggccggac cccctagcct cggattgcac
      601 agccggcacc ctgaagctga aggaggccac agcgagcaat ggcctgaaag cccatggctg
      661 cccctcagga cctggacatc gctgtgtggt tggctgcggt gcatctggag cagtatgcag
      721 acactttccg acggcatggc ctagctacag ctggtgcagc ccaacgtctg ggccatgagg
      781 agctgaggca tttgggcatc agtgctactg gacaccggaa acgcatcttg cgcctgttgc
      841 agtcaggctc tgctgaaggt ttcctggatt ctcaactgga tagtaccatg gagccaactc
      901 ccagcccagc ccctgatgcc caaccctcca agcctgtgcc taagcccaga acggtgtttg
      961 ggctcagcaa ccctgccaat gcccagaagc ctggactgaa cccaatcttc tggaatccag
     1021 aagtatccag gaactcagag tgtacacaga ggtcccctcc tgtccttccg tcttcctctg
     1081 aacagccttc agccctgaat accatggaga tgatgcccaa tgccatctac tttggcctgg
     1141 acttaagagg tcgggcccag gcagctcagg acctgactcc agacagttcc caggcaactg
     1201 tcccaacccc tgccttcagg cctacgacag gcacagtgca cattatggat cctggttgcc
     1261 tgtactatgg tgtccagcct gtgggggtcc caggagtccc tgacagaaga gatggcagag
     1321 gtgtctgtca ggaaagggct gaacacagca gacaggatca ggagacacgg gaggatgctg
     1381 gttatgccag cctcgagcta cctggggact ccattctttc gctacccacc caggatgcag
     1441 agaccagtga tgacctcatt tcgccctacg ccagtttctc ctccacagca gatcgtccag
     1501 tgcctctgct cagcggctgg ctggacaagc tctcgcctca gggaaactat gtgttccaga
     1561 gacgtttcgt gcagttcaac ggaaggagtc tgatgtactt tggcagtgac aaggacccct
     1621 tccccaaagg tgtgatccct ctgactgcca tcgagatgac ccgaagcagc aaggacaaca
     1681 aattccaggt cattaccggc cagagagtat ttgtgttccg cacagagagt gaggctcagc
     1741 gtgacatatg gtgctctaca ctgcaatcct gcctgaagga gcagcgcctc ctgggccacc
     1801 cccgaccccc tcacccacca cgacccctcc gcacgggcat gttagagttg cgtggacaca
     1861 aggccaaggt gtttgctgcc ttgatccctg gagagctggc actgtacaag agtgagcagg
     1921 ccttctcact gggcattggg atctgcttca ttgaactgca aggctgcagt gtccgggaga
     1981 ccaagagtcg aagctttgat ctgctcacac cccatcgctg cttcagcttc acagccgagt
     2041 ctgggggggc tcgacagagc tgggcagtcg ctctacaaga agcagtaacc gagaccctgt
     2101 ctgactacga ggtggctgag aaggtctggt caaacccggc aaaccggcat tgcgcagact
     2161 gcagggcctc ccggccagat tgggctgctg tcaacctggg ggtagtcatc tgcaagcagt
     2221 gtgcaggtca gcaccgggcc ctgggctctg ggatctccaa ggtgcagagc ctgaagctgg
     2281 acactagcgt ctggactaat gagatagtgc agttgttcat tgtcctggga aatgatcgtg
     2341 ccaattgctt ctgggcaggg gcactccccc caggtgaagg gctacatcca gatgcagccc
     2401 ctggccctcg aggagagttc atctcccgaa agtataagtt gggtctctac cggaagcccc
     2461 accctcggca tccagatcac agccagcttc tacaggcact gtgtgcagct atggtgggac
     2521 ccaacctgct aaagaacatg acccagctcc tctgtgttga agcctctgag ggagaggaac
     2581 ccttgtctcc ttcagccctc aatggcagct tgcttagcct tctcccttca gactcttccc
     2641 ctggagtata caatgaggtg gtggtgcctg ccacttacag aggtttcctg tactgtggtc
     2701 ccatcagcaa caaggctgga gccccacccc ttcgcagggg ccgggacgct cctccccgcc
     2761 tgtggtgtgt gctgggagct gctctggaaa tgtttgcctc agagagcagc tctgaacccc
     2821 tcagccttct ccagccccag gatgttgtat gtttgggcat aagtccccca cctgctgatt
     2881 caggtgacct tgacaggttc cccttttcct ttgaactcat cctcactggg ggaagaattc
     2941 agcattttgc cactgatgga gcagacagtc tagaggcctg gatcagcgca gtaggcaagt
     3001 ggttttcccc gctcagctgt caccagctat tgggccccgg gctgctgcgg atgggtcgcc
     3061 tgtggctacg gtccccctcc cacgcaggcc tggcccctgg tctctggctg tcagggttcg
     3121 gcctccttcg tggtgatcat ctcttcctgt gcccagcgcc cggccctgga ccccctgctc
     3181 ccgaggacat ggtgcattta cggcgtctac aggagatcag cgtggtctct gcagccgaca
     3241 ctccagacaa aaaggagcat ttggtccttg tagagacagg aaggaccctg tatttgcagg
     3301 gggaaggcag gctagatttt gcagcgtgga acacggccat tggaggtgct gctggagggg
     3361 gtggaacggg cctgcaggag cagcagatga gccggggaga tatccctatt atagtggatg
     3421 cttgcattag ttttgtcacg cagcacgggc ttcggctgga gggtgtatat cggaaaggag
     3481 gtgctcgggc ccgcagcctg cgactcttgg ctgagtttag gcgggatgcc cggtcagtga
     3541 agcttagacc acgggaacac tttgtagaag atgttactga cacactcaaa cgcttctttc
     3601 gagagcttga tgaccccgtg acctctgcta ggttgctgcc tcgatggaga gaagctgcag
     3661 agcttcccca gaagaatcag cgcctggaga agtacaaaga agtgattagc tgcctgcctc
     3721 gagtcaaccg ccggacactg gccaccctca ttgggcatct gtatcgggtg cagaagtgtg
     3781 cggctctaaa ccagatgtgc acgcgaaacc tggccctact gtttgcacct agtgtgttcc
     3841 agacagatgg gaggggagaa catgaggtcc gggtactgca ggagctcatc gatggctaca
     3901 tctctgtctt cgatattgac tccgaccagg cagctcagat tgacttggag gtcagtctca
     3961 tcaccacctg gaaggacgtg cagttgtccc aggcgggaga cctcatcatg gaggtttata
     4021 tagaacagca gcttccagac aattgtgtca ccctaaaggt gtccccaaca ctgactgctg
     4081 aggagctgac taaccaggtg ctggagatgc gaggggcagc atcagggaca gacttgtggg
     4141 tgacatttga aattcttgat catggagagc ttgagaggcc actacacccc aaagaaaagg
     4201 ttctagagca ggccttgcaa tggtgccagc tcccagagcc ctgctcagcc tctctgcttc
     4261 tgagaaaagt ctctatggca cacgctggct gcctcttcac aggagtccgt cgggagagcc
     4321 cacgggtggg gctgctacgg tgccgtgagg aaccacctcg cttgctggga agccgtttcc
     4381 aggagaggtt ctttttggtg cgtggccgat gcctgctgct actcaaggag aagaagagct
     4441 cgaagccaga acgagagtgg tctctggaag gtgccaaggt ctacctggga atccgtaaga
     4501 agttaaagcc tccaacacta tggggtttca cgttgatatt ggaaaagatg cacctctgtc
     4561 tgtcctgtac tgatgaggag gagatgtggg actggaccac aagcatcctt aaagcccagc
     4621 atgatgacca gcagtcagtg gttttacgtc gtcattcctc ctctgacctt gcccgtcaga
     4681 agtttggcac tatgcccttg ctgcccatcc gaggagatga cagtggagcc accctactct
     4741 ctgccaatca gaccctgcgg cgactgcaca accggagaac cttatccatg ttctttccaa
     4801 tgaaatcgtc tcaggggtct gtggaggagc aagatgagct ggaggagcct gtgtatgaag
     4861 agccagtata tgaggaggtt ggggccttcc ctgagcttac caaggacatg acctccacat
     4921 gggagtggtc gaccaagtca gacacacccc ttaccagcca gaggtccttt gatcaaaccc
     4981 ccctcaccaa agcaagcatg ttggtccagg aggagaggat acctgagcct cctccaggac
     5041 ccccttcaaa aagcagtcct caggcacgag ggtccctaga ggaacagctg ctccaggagc
     5101 tcaacaacct catcttgagg aaaggagaac ctgccacgtg tccagaaagt ccttcccagc
     5161 ccaccagtcc tcaatccccc agccccacca gccttccaac acagacaccc agcttaccca
     5221 cccaaatccc ctgcgcttcc aatccaccct ccagccagcc cctcacatga ccccagggcc
     5281 agcagttgag gaggaaggta accagaggag aagccaggct ctcaccgtgg cagacaattg
     5341 ctgggagcat cttctgccct ggatggatga ctctgggatc cagtatggta ccatggaagg
     5401 agcactggac tgagaaccct ggagattgtg tgtctcaggg aagatcatgg cccctctctg
     5461 ggcccagcct atttgtctat actatgaagt cactaaaata aggagagggg tgaacaccga
     5521 actgtttctg agctaggagc cctgatattt ccctcagtag gagcagctcc tggtgtatat
     5581 atttgatata ggggttcagt gagaggtttg cggcataaga atggttttac tgcactagag
     5641 gaaagtgaaa gttgggaagc atgataccca aatctatgtt attctactcc ctatgtgcta
     5701 aaactgcctt gaggccctgg aatggggtgg ctgattggtg ttgggagctg gggcccagag
     5761 ggagttgaaa agcaataggt cactattaat aaactttgga accgaaaggc tcattttttt
     5821 caacaacatt cattcattca acaagtttgt actgagcacc taattggtgc cgccaagtca
     5881 caaacaaatc aaacagggtc cttgctctta cggagcctac agaaaggaaa ctaaatacac
     5941 acatcaatca gaggccagtt caaagtgctt caaagaaact aaactcagcg acagcttgag
     6001 ctaatgtgga tgtgcccttt acactaggtg gatggggtag aagcctttga ggagcagaag
     6061 caatggcaag gagctgataa ggggagtact tggagcagga gagggcaggg gcaggacagg
     6121 gcaggcagca ggcactaaag ctgtgcagtg gcaaaagtct tggccctgtg ggaggataga
     6181 agtagctggg acaaggagtg ggaagtagga gaggcaaggc agaaagatag gcaaaggctg
     6241 agaatggtga tccacacatt taatccccgc actcaagagc agaggcaagg ggatcttcga
     6301 gttcaaagtc agcctgatct acagagttaa gttccaggcc agccaaggct acatagtgaa
     6361 atcctgttcc ccccaaaata ttaaaaacaa aacaaaaaac aatagggaaa actctgagga
     6421 cataggaggc agagagaagc ctctcattac atcttctggc tcaagccttt gctagcctca
     6481 cagttaactg cttccggcct ttccttctca gccataaatc ttcagttttt tggaacttaa
     6541 ctagaaatcc catgacaagg atagaatatg caataaatac cttgtgtaat tctactggct
     6601 tttgaatctc ctgagttacc aatcacattt cttttatcga aagagacaga aggaaaatgt
     6661 tttccgtaat gcaatggctg taagatgtaa actgaagcct gttggttgta gcacttacct
     6721 ttaattccag cactggggag gcagaggcag gccatctctg tgggtttgag gccagcctgg
     6781 tctacagact aagttccagg acagccaaag ctacacaaag aaaacgtgtt taaaacaaac
     6841 aaacaaacaa acaaaaaagc aaacaaacaa acaaaaaaac cctcagcaat ctgagaacca
     6901 ccaaagaaca gacattgcta gtgctaagac acttaattgc tttctttcct ttgaggagcc
     6961 ccatacacac ctgggtacaa acatattttc ccctatgctc cctccggaag cacattctat
     7021 aactccctta cttggctgtg tcttactttc ttctgattga attttcttta tgctcttgtg
     7081 ctctaaccta tattaaatta tctttaataa aatttctaac tccgcctca
//
