LOCUS       XM_006229899            5263 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ArfGAP with RhoGAP domain, ankyrin
            repeat and PH domain 1 (Arap1), transcript variant X2, mRNA.
ACCESSION   XM_006229899
VERSION     XM_006229899.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_006229899.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5263
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5263
                     /gene="Arap1"
                     /note="ArfGAP with RhoGAP domain, ankyrin repeat and PH
                     domain 1; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 60 ESTs, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 80 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:361617"
                     /db_xref="RGD:1310385"
     CDS             328..4692
                     /gene="Arap1"
                     /codon_start=1
                     /product="arf-GAP with Rho-GAP domain, ANK repeat and PH
                     domain-containing protein 1 isoform X1"
                     /protein_id="XP_006229961.1"
                     /db_xref="GeneID:361617"
                     /db_xref="RGD:1310385"
                     /translation="MAEGHDAALSVAEWLRALHLEQYTALFEQHGLVWATECQGLSDA
                     SLVDMGMNLPGHRRRILAGLHRAHAPPPVPVPRPAPRPVPMKRHIFRSPPVPVTPPEP
                     PPTAGEDQGLPAAPPIPPRRSCLPPACFTPPSTAPPDPVLPPLPAKRHSVEPSLPPVP
                     PRTGPPYPQTSLLSKEELLLPSVSPWSQPEPTETPSTLLPAFPQGPLQPPSPPPCPPV
                     IPPKPLRLLPEFDDSDYDDVPEEGPGAPASVMTKEEPLPSRVPRAVRVASLLSEGEEL
                     SGDDAEDEDDHAYEGIPNGGWPTIGLNPPLSSLIPDLPLHPMDELPGGSTPTTPVIKA
                     GWLDKNPPQGSYIYQKRWVRLDADHLRYFDSNKDAYSKRFVPVACICRVAAIGDQKFE
                     VITNSRTFAFRAESDVERNEWMQALQQAVVEHRAHIRLSSASVLGVRGGTEQPDHAGS
                     LELRGFKNKLYVAVAGDKVQLYKNLEEFHLGIGITFIDMNVGNVKEVDRRSFDLTTPY
                     RIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAAQPDWAS
                     INLCIVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIQLFLQLGNGPGNHFWAAN
                     VPPSEALEPSSSPGARRYHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAET
                     QALLGCGAGVNCFSGDPAAPTPLALAEQAGQTLQMEFLRNNQSTEVPRLDSVKPSEKH
                     YSITLPTVSHSGFLYKTASAGKPLQDRRAREEFSRRWCVLSDGVLSYYENERAVTPNG
                     EIRASEIVCLAVSPLDTHGFEHTFEVYTEGERLYLFGLENAELAHEWVKCIAKAFVPP
                     LAEDLLARDFERLGRLPCKAGLSLQQAQEGWFALTGSELRAVFPEGPWEEPLQLRRLQ
                     ELSIQGDSENQVLVLVERRRTLYIQGERRLDFMAWLGAIQKAAASLGDTLSEQQLGDS
                     DIPVIVYRCIDYITQCGLTSEGIYRKCGQTSKTQRLLDSLRQDARSVHLKEGEQHVDD
                     VSSALKRFLRDLPDGLFTRAQRLAWLEASEIEDEEEKISRYRELLVHLPPVNRATVKA
                     LISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTDGQDYKAGKVVEDLISHYVVVFSVD
                     EEELRKQREEVTAIVKMRVAGTASGTQHAGDFICTVYLEEKKVETEQHVKIPASMTAE
                     ELTLEILDRRNVSIREKDYWTCFEVNEKEEAERPLHFAEKVLPIVHGLGMDSHLVVKK
                     YPSMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKE
                     VRSQRPWSGAPETSHRPEKEWPVKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQW
                     YLCCDTQMELREWFATFLSVQHDGLVWPSEPSRVSRAVPEVRMGSVSLIPLRGSENEM
                     RRSVAAFTADPLSLLRHV"
ORIGIN      
        1 tgcaagctgc tgctccaacc tctggggcgg ccggtcttgc ttccccgctg gtctcctctc
       61 cagcgtactt ggtgtgtgct gtgtgctgtg tggtcccgag ccttgtacat tcagttcccg
      121 ttgcatggaa cagtgttctt cctgtctcca cccgtcaagg cccagggagg cagcccattc
      181 tccaaagcgt ctgggctaca gcaggggact tgcttccacc tcagagcacc atgaggagcc
      241 cttgggacta ggaacgacgt ccttggagga ccaggtgtcc ttggtggcag atctgagcct
      301 agccctggac ctctgcagcc agaagccatg gcggagggcc atgatgccgc actgtcagta
      361 gcggagtggc tgcgggcact gcacctggag cagtacacag cactctttga gcagcatgga
      421 ctggtgtggg ccactgagtg ccaaggcctc agcgatgcca gcctggtgga catgggcatg
      481 aacctccctg gccaccgccg ccgtatcctg gctggtctgc accgtgccca tgcacccccg
      541 ccggtccctg tgcctcgccc tgccccacga cctgtgccga tgaagcgaca catcttccgg
      601 tcaccacctg tgcctgtcac tccacctgag ccgccaccca cagctggaga ggaccagggt
      661 ctgcctgctg ctccacccat tccaccccgc aggagctgcc tcccacctgc ctgcttcact
      721 ccaccatcca cagcaccccc agatcctgtt ctgcccccac tgcctgccaa gaggcactca
      781 gtagaaccga gccttcctcc tgtacctcct cgaaccgggc ccccctatcc gcagaccagc
      841 cttctctcta aggaggagtt actgctgcca tccgtatcac cctggtccca accagagcct
      901 acagagactc cgtccaccct cctgcctgcc tttccacagg ggcccctgca gcctccgtct
      961 cctcctccct gccctcctgt gattcccccc aagcctcttc gcctgctccc tgagtttgac
     1021 gactctgact atgatgatgt tccagaggag gggccagggg ccccagccag cgtgatgacc
     1081 aaggaggagc ccctgccaag cagagtccca cgggccgtgc gtgtggctag tctgctgagc
     1141 gagggggagg agctgtctgg ggatgatgct gaggatgagg atgatcacgc ctatgagggt
     1201 atccccaatg gcgggtggcc aaccattggc ctgaatccac ccttaagcag cctgatccct
     1261 gatctcccac tgcaccccat ggatgagttg cctgggggtt ccacccccac cacacctgtc
     1321 atcaaggctg gttggctgga caagaaccca ccacaggggt cttatatcta tcagaagcga
     1381 tgggtgagac tggatgctga tcacctgcga tactttgaca gtaacaagga tgcctactct
     1441 aagcgctttg ttcctgtagc ctgcatctgc cgagtagctg ctattggaga tcagaagttt
     1501 gaagtgatca caaacagtcg gaccttcgcc ttccgggcag agagcgatgt ggagcggaat
     1561 gagtggatgc aggccctgca gcaggcggtg gttgagcatc gagcccatat tcggctctct
     1621 agtgcttctg tgttgggagt tcgaggaggc accgagcagc ctgaccatgc tggcagcctg
     1681 gagctacgag gcttcaagaa taagctttac gtggccgtgg ctggggacaa agtacagctc
     1741 tataagaatc tggaggagtt ccacctgggc attggtatca ccttcatcga tatgaacgtg
     1801 ggcaacgtca aggaagtgga ccggcgcagc ttcgacctca ctacccccta ccgcatcttc
     1861 agcttctcgg ctgattcaga gttagagaag gaacagtggc tggaggccat gcagggagcc
     1921 attgcagagg cattatctac ctcagaggtg gccgagcgca tctgggctgc agcccccaac
     1981 aggttctgtg ccgactgtgg ggctgcccag cctgactggg cctccatcaa cctctgcatc
     2041 gtcatctgca agcgctgtgc aggggagcac cgtggcctgg gtgcaggagt gtccaaggtg
     2101 cggagcctga agatggacag gaaggtgtgg acagagacac tcatccagct cttcttacag
     2161 ctgggcaatg gccctgggaa ccacttctgg gctgccaacg tgccccctag cgaggccctg
     2221 gagcccagca gcagccctgg cgcccggcgc tatcacctgg aggccaagta cagggagggc
     2281 aagtaccgcc gctaccaccc actcttcggc aaccaggagg agctggacaa ggccctgtgt
     2341 gctgcagtta ctaccactga cctggctgag acccaggcac tcctgggctg tggggctggg
     2401 gtcaactgct tctcagggga cccagccgct cccacacccc tggctcttgc tgagcaagcc
     2461 ggacagactc tgcagatgga gtttctacgg aataaccaga gcacagaggt tccccggttg
     2521 gactcagtga agccctcgga aaagcactac tccattaccc tgccaactgt gagccacagt
     2581 ggcttcctgt acaaaactgc ttctgccggc aagcctctgc aggaccgccg tgcccgggaa
     2641 gagttcagcc ggcgctggtg tgtcctgagt gatggggtcc tgagctacta tgagaacgaa
     2701 cgggcagtga cacccaatgg ggagatccgg gccagcgaga tagtatgcct agcagtttct
     2761 cctctggaca cccatggctt tgagcacacc tttgaggtgt acacagaggg agaacggctg
     2821 tacctgtttg ggctggagaa tgctgagctg gctcatgagt gggtcaagtg cattgccaag
     2881 gcgtttgtgc ctcccctggc tgaggacctg ctagcccggg actttgagcg tcttgggcgc
     2941 ctaccctgta aagctggcct gagccttcag caggcccagg aaggctggtt tgccttgact
     3001 ggctctgagc tccgggctgt cttcccagag gggccctggg aagagccgct gcagctccgg
     3061 agactgcaag agctttctat ccaaggagac agcgagaacc aagtgctggt gctggtagag
     3121 cggaggagga cactgtacat ccagggtgag cggcggctgg acttcatggc ttggctaggg
     3181 gccatccaga aagcagcagc cagcttagga gacacactat cagagcaaca gctcggggac
     3241 tcggacattc cagtgatcgt gtaccgctgt atagactaca tcacgcagtg tggcttgacc
     3301 tcagagggta tctatcgaaa gtgtggtcag acctctaaga ctcagagact gctagacagc
     3361 ctgcggcagg atgcacgttc tgtgcacctg aaagagggag aacagcacgt ggatgacgtc
     3421 tcctctgcac tcaaacgctt cctcagggat ctgcccgatg ggctcttcac tcgtgcgcag
     3481 cgcctggcct ggctggaggc ctctgagatc gaggatgagg aggaaaagat ctccaggtac
     3541 cgagagctct tggtacatct gccccctgtc aacagggcca ctgtgaaggc ccttatcagc
     3601 catctgtact gtgtacagtg cttctcagac acaaaccaaa tgaacacaca caacctggct
     3661 attgtgttcg ggcctacgct gttccagacg gatggtcagg actacaaggc gggcaaggtg
     3721 gtagaagacc tcatcagcca ttatgtggtg gtgttcagtg tggacgagga ggagctgagg
     3781 aagcagaggg aggaagtcac agccattgtg aagatgcgag tggctggcac cgccagcggg
     3841 acccagcatg ccggtgattt catctgcacc gtgtacctgg aggagaagaa ggtggagact
     3901 gagcagcatg ttaagatccc agcatccatg acagcagagg agcttactct ggagatcctt
     3961 gaccgccgca acgtgagcat cagggaaaag gactactgga cttgctttga ggtcaacgag
     4021 aaggaggagg cagagcgccc gctgcacttt gcggagaagg tgctgcccat tgtgcacgga
     4081 ctgggcatgg acagccatct ggtggtgaag aagtacccgt ccatggaggc catgctgttg
     4141 tacttggcca gccgtgtggg tgacaccaag catggtatga tgaagttccg tgaagaccgc
     4201 agcctcctgg gtctggggct gccttcaggt ggcttccacg atcgatactt cattctcaac
     4261 agtagctgcc taagactcta caaggaggtc cggagccaga ggccgtggag cggggcccct
     4321 gagaccagtc accggcccga gaaggagtgg cctgtcaaga gcctcaaagt ctacctgggt
     4381 gtaaagaaga aactgcggcc acctacttgc tggggcttca cggtggtaca tgagacagaa
     4441 aagcatgaga agcagcagtg gtacctctgc tgtgacacac aaatggaact tcgagagtgg
     4501 tttgccacct tcctctctgt acagcacgat ggcctggtgt ggccctcaga gccctctcga
     4561 gtgtcccggg cagtgcctga ggtccggatg ggcagtgtat cactgatccc tctacgcggc
     4621 agtgagaatg agatgcgccg gagcgtggca gccttcactg ccgaccccct ttccctcctc
     4681 cgtcacgtct gagcatagga gtcattctga cttgggacgc catctctgcc ctcaggagct
     4741 ttcctgttca gactcccccg tgctctgcgt gtttggtgtg agccaacaga aaacacgggg
     4801 aagccatacc cacatcccac atcctgactg cagcgcaggc tccttggctg ggcaggaatg
     4861 ggctggcagt ggggatttcc caggaggggc ccttattctc caggcatgca atgttcttga
     4921 cctggcttgc ttacccaggg tcactctcct ctcagtaggg ttggaaagat ggacagaaat
     4981 caggagctgt gcaggagagg ctcaagggtt tggggcccca ctaggaggga gcccacccga
     5041 ttcccacagg cccctgaaca ggaaaaggtg atactctgaa agaactccta gggggtctac
     5101 aagggagctc atggggagct tctacaggat gaaatctgga cttgaggatg tcagccctct
     5161 tctggtgtgt gctggcaggg atgccaggct gtggctgtct gccatccctt ccccactttg
     5221 gatacttttt gataatataa atatatctgt atattttacc cta
//
