LOCUS       NM_001109009            1093 bp    mRNA    linear   ROD 13-MAY-2024
DEFINITION  Rattus norvegicus aquaporin 12A (Aqp12a), mRNA.
ACCESSION   NM_001109009 XM_001069924 XM_346076
VERSION     NM_001109009.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1093)
  AUTHORS   Ichikawa,R., Takeda,T., Kakigi,A., Ito,H., Kobayashi,T. and
            Hyodo,M.
  TITLE     Expression of AQP-10, -11 and -12 in the rat stria vascularis
  JOURNAL   Acta Otolaryngol 144 (2), 96-99 (2024)
   PUBMED   38511591
  REMARK    GeneRIF: Expression of AQP-10, -11 and -12 in the rat stria
            vascularis.
REFERENCE   2  (bases 1 to 1093)
  AUTHORS   da Silva,I.V., Cardoso,C., Mendez-Gimenez,L., Camoes,S.P.,
            Fruhbeck,G., Rodriguez,A., Miranda,J.P. and Soveral,G.
  TITLE     Aquaporin-7 and aquaporin-12 modulate the inflammatory phenotype of
            endocrine pancreatic beta-cells
  JOURNAL   Arch Biochem Biophys 691, 108481 (2020)
   PUBMED   32735865
  REMARK    GeneRIF: Aquaporin-7 and aquaporin-12 modulate the inflammatory
            phenotype of endocrine pancreatic beta-cells.
REFERENCE   3  (bases 1 to 1093)
  AUTHORS   Itoh,T., Rai,T., Kuwahara,M., Ko,S.B., Uchida,S., Sasaki,S. and
            Ishibashi,K.
  TITLE     Identification of a novel aquaporin, AQP12, expressed in pancreatic
            acinar cells
  JOURNAL   Biochem Biophys Res Commun 330 (3), 832-838 (2005)
   PUBMED   15809071
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473997.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_346076.3, XM_001069924.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5756307,
                              SAMEA5760383 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1093
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q36"
     gene            1..1093
                     /gene="Aqp12a"
                     /gene_synonym="Aqp12; Aqp12b; RGD1562727"
                     /note="aquaporin 12A"
                     /db_xref="GeneID:367316"
                     /db_xref="RGD:1562727"
     exon            1..674
                     /gene="Aqp12a"
                     /gene_synonym="Aqp12; Aqp12b; RGD1562727"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..940
                     /gene="Aqp12a"
                     /gene_synonym="Aqp12; Aqp12b; RGD1562727"
                     /note="aquaporin 12B"
                     /codon_start=1
                     /product="aquaporin-12"
                     /protein_id="NP_001102479.1"
                     /db_xref="GeneID:367316"
                     /db_xref="RGD:1562727"
                     /translation="MASLNVSLSFFFATCAICEVARRASKALLPAGTYASFAREAVGA
                     AQLAACCLEMRVLVELGPWAGGFGPDLLLTLVFLLFLVHGVTFDGASANPTVALQEFL
                     MVEASLPSTLLKLLAQVLGAQAACALTQRCWTWELSELHLLQSLMAVHCSSTLRTSVL
                     QGTLVEGACTFLFHLSLLHLQRSLLVYRAPALALLVTAMAYTAGPYTSAFFNPALAAS
                     VTFHCSGNTLLEYAHVYCLGPVAGMILAVLLHQGHLPRFFERNLFYRQKSKYRTPRVK
                     LSPGSVDTKMLKGE"
     exon            675..791
                     /gene="Aqp12a"
                     /gene_synonym="Aqp12; Aqp12b; RGD1562727"
                     /inference="alignment:Splign:2.1.0"
     exon            792..1093
                     /gene="Aqp12a"
                     /gene_synonym="Aqp12; Aqp12b; RGD1562727"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccttgggctg tggggccagc cagtctccca cacgtctgtc accttgctcc ttgtagaacc
       61 cagactgatg gccagtctga atgtgtccct ctctttcttt tttgctacct gcgccatctg
      121 tgaggtggct aggagggcat ctaaagccct gctcccagca ggtacctatg ccagttttgc
      181 acgggaggca gtgggcgcag cccagctggc agcctgttgc ctagagatgc gagtgctggt
      241 ggagctcggc ccctgggctg ggggtttcgg gcccgacctg ttgctgaccc tggtgttcct
      301 gcttttccta gtgcatgggg tcacctttga cggggcctct gccaacccca ctgtggcctt
      361 gcaggagttc ctcatggtgg aggcgtcgct gcccagtact ctgctgaaac tgttggccca
      421 ggtgctgggc gcgcaggccg cctgtgccct gacccagcgc tgctggacct gggagctcag
      481 cgaactacac ttgctgcaga gcctcatggc tgtacactgc agctccaccc tgcggacatc
      541 cgtgctgcag ggcacgctgg tggagggcgc ctgcaccttc ctcttccacc tgagcctcct
      601 ccacctgcag cgcagccttc ttgtctacag ggcacctgcc ctggccctgc tggtcacggc
      661 catggcctac acagctgggc cctacacgtc tgccttcttc aatcctgccc tggctgcctc
      721 tgtcaccttc cactgttctg ggaacacctt gctggagtat gcccacgtgt actgcctggg
      781 tcctgtggca gggatgatcc tggctgtcct actccatcag ggccacctcc cacgcttttt
      841 cgagagaaat ctgttctacc ggcagaaaag caaataccga acccctaggg tgaagctgtc
      901 cccaggttct gtggatacca agatgctcaa aggggagtag tggcaaaggg ctgtggccta
      961 tgggtaccag ggcagcagcc actggggatc tggatgagct gccttgctca ctgaagcttc
     1021 agtcacctcc cgagtcttct ggtctaccct ccacaaaatc atttgccaat aaaccattgt
     1081 taaggcccac ccg
//
