LOCUS       NM_001100969            6384 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus amyloid beta precursor protein binding protein 2
            (Appbp2), mRNA.
ACCESSION   NM_001100969 XM_001081113 XM_220805
VERSION     NM_001100969.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6384)
  AUTHORS   Zheng,P., Eastman,J., Vande Pol,S. and Pimplikar,S.W.
  TITLE     PAT1, a microtubule-interacting protein, recognizes the basolateral
            sorting signal of amyloid precursor protein
  JOURNAL   Proc Natl Acad Sci U S A 95 (25), 14745-14750 (1998)
   PUBMED   9843960
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On or before Jun 1, 2008 this sequence version replaced
            XM_220805.4, XM_001081113.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC169030.1, SRR26643299.44517.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-411               JAXUCZ010000010.1  70596857-70597267   c
            412-500             JAXUCZ010000010.1  70582018-70582106   c
            501-652             JAXUCZ010000010.1  70580608-70580759   c
            653-776             JAXUCZ010000010.1  70579416-70579539   c
            777-945             JAXUCZ010000010.1  70574798-70574966   c
            946-1035            JAXUCZ010000010.1  70569983-70570072   c
            1036-1103           JAXUCZ010000010.1  70567663-70567730   c
            1104-1209           JAXUCZ010000010.1  70567479-70567584   c
            1210-1334           JAXUCZ010000010.1  70566663-70566787   c
            1335-1420           JAXUCZ010000010.1  70564128-70564213   c
            1421-1611           JAXUCZ010000010.1  70562351-70562541   c
            1612-1777           JAXUCZ010000010.1  70560904-70561069   c
            1778-6384           JAXUCZ010000010.1  70555212-70559818   c
FEATURES             Location/Qualifiers
     source          1..6384
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..6384
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /note="amyloid beta precursor protein binding protein 2"
                     /db_xref="GeneID:303396"
                     /db_xref="RGD:1306488"
     exon            1..411
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
     CDS             274..2031
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /note="protein interacting with APP tail 1; APP-BP2;
                     amyloid beta precursor protein (cytoplasmic tail) binding
                     protein 2"
                     /codon_start=1
                     /product="amyloid protein-binding protein 2"
                     /protein_id="NP_001094439.1"
                     /db_xref="GeneID:303396"
                     /db_xref="RGD:1306488"
                     /translation="MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVY
                     YKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFS
                     RRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWF
                     RAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANRAALYGELCALLFA
                     KSHYDEAYKWCVEAMKEITSGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLA
                     RDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHE
                     DLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAID
                     CHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEE
                     MHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGE
                     GYSGLEYDYRGLIKLYNSTGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVNSSPQS
                     TEEVVQSFLMSQNVEGPSC"
     exon            412..500
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            501..652
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            653..776
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            777..945
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1035
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1103
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1104..1209
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1334
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1420
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1611
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1777
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1778..6384
                     /gene="Appbp2"
                     /gene_synonym="PAT1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgggctcgtt cttctgttgg gaatgtgagg ctctcggttc ggtcgtgctc tgcgttcgtc
       61 cggatcttcc ctgtccgccg ctgccgcgcc actgccaccg ctagcaccgt ctgcccttag
      121 tccgcgcgca cacgcggagg ccgggcagcc gggtccgaga ggcgcgcgcc ttcgtggtcg
      181 ccgcccctcg gaagcctccg gagcctcaca cacgggttcg ctacggaggg aggcggaggc
      241 ctgcgggagg aggcggagga ggagcgaggg aagatggcgg ccgtggagct cgagtggatc
      301 ccggagacgc tctacaacac cgccatctcc gctgtcgtgg acaactacat ccgctcgcgc
      361 cgcgacatcc gctccttgcc ggagaatatc cagttcgacg tttactacaa gctttaccaa
      421 cagggacgct tatgtcaact gggcagtgaa ttctgtgaat tggaagtttt tgctaaagtt
      481 ttgagagctt tggataaaag acatttgctc caccactgtt ttcaggccct gatggaccat
      541 ggtgttaagg ttgcttctgt cttggcctac tccttcagta gacggtgctc ttacatagca
      601 gagtcagacg ctgctgtcaa ggagaaggcc atccaggttg gctttgtctt aggtggcttt
      661 ctttctgacg caggctggta cagcgatgct gagaaggttt tcctgtcctg ccttcagttg
      721 tgtaccctac atgatgagat gctccactgg tttcgagcag tagagtgttg tgtgaggttg
      781 cttcatgtgc gaaatggaaa ttgtaaatat cacctaggtg aagagacatt taaattagct
      841 cagacgtaca tggacaagct gtctaaacat ggccagcaag caaatagagc tgctctctat
      901 ggagaactat gtgcgctcct gtttgcaaaa agccactatg atgaggcata caagtggtgc
      961 gttgaggcaa tgaaggagat tacatcaggc ttaccagtca aagttgtggt ggatgtttta
     1021 agacaagctt ctaaggcttg tgtagtcaaa cgtgaattta agaaggcaga gcagttaatt
     1081 aaacatgcag tgtatttggc acgagatcat tttggatcca aacacccaaa atactccgac
     1141 acactgttag attatgggtt ctacttgctc aatgtagaca atatctgcca gtcggttgca
     1201 atttaccagg cagccctcga cattcgacag tcagtgtttg gtggcaaaaa tattcatgta
     1261 gcgacagctc atgaagacct ggcttactct tcgtatgtgc accagtacag ctctggaaaa
     1321 ttcgacaacg ccctatttca tgcagaaaga gccattggta tcattaccca catcctacct
     1381 gaagatcatc ttcttttggc ttcttcaaag agggtgaaag cacttatatt agaggagatt
     1441 gcaatcgact gtcataacaa ggagacggag cagaggctgc ttcaggaagc acatgacttg
     1501 cacttgtcct cactgcagct agctaagaaa gcattcggag aatttaatgt acagactgca
     1561 aagcactatg ggaaccttgg aagactttat cagtcaatga gaaaatttaa ggaagctgaa
     1621 gaaatgcaca taaaagcaat tcagattaag gagcagctcc ttggtcaaga agattatgaa
     1681 gtggcccttt cggtgggaca cctggcatct ctgtacaatt atgacatgaa tcagtatgaa
     1741 aatgctgaga aactgtacct tcggtcgata gcgattggga agaagctgtt tggcgaaggc
     1801 tacagcgggc tggagtatga ctaccgtggc ctcattaagc tctacaactc cactgggaac
     1861 tatgagaagg tgtttgagta ccacaacgtc ctgtctaact ggaaccggtt gcgagaccga
     1921 cagtattcag tgaccgatgc ccttgaagac gtcaacagca gcccccagtc cactgaggaa
     1981 gtggtgcagt ccttcctgat gtctcagaat gttgagggac caagctgctg agggacagcc
     2041 tcagctaaca attacctttt cccagattcc agggaattca tactgtgaaa tcagaaccat
     2101 gttgttttta gggctggcat ttgcattgaa acactggtcc agtccacaga agaccctgtt
     2161 tcgggtagtc ctgcattgca gttctgtaca gtaagcgtct tgttgtcagc atgtgccgcg
     2221 tgtaagtagt cccacactct caccctagta gaacaacagg aaacgttttt tttttttctt
     2281 tttaaaaaat aattcatttt tcagaaagtc tgaaagaaaa aaaaaagaac ccctaaataa
     2341 aactatttaa gagtttaaaa gagttgcatt cttattatgt aaggatgatt tcaaaaactt
     2401 tttaacatat aattcttcca tgtggaggca ttcaatactg tattgtaagg aaattttatg
     2461 gaaaactctt tatatgcagt atggaaaagt aacacaggta ctaataaggg gggaggggca
     2521 ccctgacata gatttggcca tctttcccag atcagggcat gcagccattc cagaactgtt
     2581 tcagtgacgg actgtcagat tcatctgact ggaccagtgt tgatctgtca gtctcaggac
     2641 accagcagtt ctaactgttt ttggtaccat ggtgagatgc tctcaagtgt ttgctgacag
     2701 gaccagaagg atctacgagg accaggcaac cgtggaaggt gttcattgga ccagtggctt
     2761 tagattgtta ctttagtgac tgcacttgcc ttttccgata gaatgatttc atttaggtag
     2821 aactagaacg cacagtacta atgcaggagt tttatttgca tcgtagatac caaactgtgg
     2881 gatatggcag tgtcggtggc aagtctttag tcttggtaca tagatggcag tgtcataagc
     2941 acgtctgtga ccatctctgc agccaccccc gtttcgtctt tgccctgata gtccatgtcg
     3001 ttatcaagca tcctggctaa gagtcaggaa gtgagtcatg ttcagatgag actttaggct
     3061 tactgtttgg tttgtgggga ttaaaagatg aatgcacaca aaagaaagtc ttagaaaatt
     3121 cattactgtt gaaaataata gtacaactag tcattttaac tgacatccag gacttcaatg
     3181 gaaaaatcct ccagttacaa tgtctgtttt actgattggg gcttttggtt tttctaagtt
     3241 tttaaagcta gccagattat ttaatgtgga gctaacactc agttcctaag ttgtgacatg
     3301 taataaaaag aaacaaaaag atcttttgct gttacctcaa ttcttagcac agtggcccac
     3361 ctggtctggt acctctgtgg ttaagaatct gggtttcccc ctattttcag gggcttctga
     3421 cttggctgtt agatgcactg ctcctggtat tgcttggagt ggtggatgag tgggtgtgtg
     3481 tcagtcaggc tttgttcttt tagcatgctt gttgggtgag gggaaagaaa gttatcatgg
     3541 agagacagaa acattaaaga cttaagaact tatcttaaac atttttttta cttcccaatt
     3601 ttacctttgt ttgaaattct cttttcagtc ttagtgatag gccagtgggt taggccttag
     3661 aagggacctt agtggggatg tcccccagca ggtgaggcaa gctctcaccc tgacacagca
     3721 acttggggtt cagacttgaa tttattcctc gaaccgtgtt tcctttaaat tcttcaaaga
     3781 attaaatttg gcaggcttgc agtttatgca gctggctccc ttccccctta atcacacaca
     3841 gtcttgtcag agtcaccttt attaccacgt agtctgtgtg acccaggagt tgcatttcta
     3901 agtgactcag ctagagcctc acaagcctat atatttaata cctccaaaga cagtttcacg
     3961 ataggctttt tgtatacttt tatttggata tttagagtcc tgtggtatgt ttgtggtata
     4021 ggaatgtcat ggtaaattgt ttcttaataa atattttaaa acaagtttcc acatgaatta
     4081 tttttattta atctgcatct ttggtggtgt gcacttacag cattttgtat aatttaccct
     4141 catcttccat agctcagtca accttaactc atcctcagtg ataaagtaaa atgaccctgt
     4201 gcttacaggg tgacagtgtc aggtgacagc cagcctcacc cccaccccca acctcattgt
     4261 cagctgctcc atctgacctt tccttaagta cagttttctg taagttaagt cagtctaatg
     4321 cctacactct agcactctgt ctgcttagcg atatgacttg atatgttctg attccagtga
     4381 aagtaatgcc ctaatcattt caaggtggga ttcatccctc agcaaggatg atgtggtaag
     4441 aaggatgcca ccgtaatttt ttttttttct ttttttcgga gctggggact gaacccaggg
     4501 ccttgcgctt gctaggcaag tgctctaccg ctgagctaaa tccccaaccc caccaccgta
     4561 attttatttt gaaaaattat taaagcagag tgtggtacat acctattatg tcagtattca
     4621 ggaggctgag tgacgtaaga tgttgagttt caggcagcct gggctacaaa gggagattgt
     4681 gtctccaaaa tctcaaaagg aaaaactgaa taaaatttac ctcagaataa tcagtagctt
     4741 gcgtgtaatt ttaagtaagg gcctatgatc tcaccctccc ctgaattctc ctatttctaa
     4801 agtctggtgc tattccattt gggggcatga gggagcttgt gcatgtgacc caggtgagcc
     4861 aacagagttt ttagtgtaca gtatttatgg gtcctcaaac tagactgccc tgaggcttta
     4921 gatctttctc catcacttta cattctttat aaacaactca ccagcaccct gcccaggtat
     4981 tgctgcccgt gagaatcgat ttgaataaag ccctttgtcc aaccgtgaga atgactccta
     5041 atgtgagcat tcagttcagg aagctgcatg tgctggcaca agggaatccc aactccacag
     5101 gaggccgaga caggagtcac ttgagattcc cccaggacag cctagtaaga ccctgtctga
     5161 agaatgcagg gagtcctgaa ggccatggac cttgtcctag tagcaccaac agcagaggct
     5221 aaacttgatg ctagctttgg ccaaaactcc gcaaattcat agtttgctaa gtaacaggtg
     5281 ttgttattac cacctttttt taatatatgt tttcccctag agtttttagc cttgctgctt
     5341 ccaatcttct ttttctagat gacaaagtta ctactggaaa aaagttattt ataagtactg
     5401 aatttttttt tttctttttt tcggagctgg ggaccgaacc cagggccttg cgctcgctag
     5461 gcaagcgctc ttccactgag ctaaatcccc aacctgaatt ttaagagttt tattttgttt
     5521 taaaaattaa catttttcac ctcttggctt tagaggactt cagattagct ggaaggcaga
     5581 tttattttgt gtaggacatt tgggttagtg tacagatctt aacacaagga gttcttttgt
     5641 ccccaaatct caggaatgtt tgagacagaa aactggcttt tcccatgata gcgatttgag
     5701 ggagagtgct ttaggattta ttaaataaca ctattgttaa ttgcagtcta ggtatctata
     5761 gcatgagtgg ccttaatgag tttgttgaag tgcacatgtt tttcaaaagt aaaatttaag
     5821 attaaatata tatgctatat atagagatat ctaggaaact tggttgtggt gcacaaagtg
     5881 tggaatcact gaatcgcagg taccatttgt ataacattgc tcgtttctgt atattccttt
     5941 tatgggaaaa tatgttgcca tggtgactaa aacttttcaa tttagtttta cttttatgtg
     6001 aatgaatgct acattttatt aaataatacc aggtcagtac tatttttata ccttattaag
     6061 taacaggggt tttagtttaa taggctcaaa ataaaaagaa aaacccttaa tggaataatt
     6121 acaaacgaat cactgtcatt ctttacagga atccccacta tcgtgccaca gtaatttcta
     6181 tagtagaatc tctggtcatt aataaatcct gaagacagtt cactgggtca gaacagcctt
     6241 tcctaccatc cccacttgta gtgcccgcca ttatttgtaa tattaaacca cactaagtat
     6301 gtttgtaacc agcattgtga tatattctgt acttgtattg ctaaatgaac tattgaccta
     6361 ataaatagtg ttcctgcatt cata
//
