LOCUS       NM_001199178             906 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus apolipoprotein O (Apoo), mRNA.
ACCESSION   NM_001199178 XM_002727568 XM_343793
VERSION     NM_001199178.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Koob S, Barrera M, Anand R and Reichert AS.
  TITLE     The non-glycosylated isoform of MIC26 is a constituent of the
            mammalian MICOS complex and promotes formation of crista junctions
  JOURNAL   Biochim Biophys Acta 1853 (7), 1551-1563 (2015)
   PUBMED   25764979
REFERENCE   2  (bases 1 to 906)
  AUTHORS   Guarani V, McNeill EM, Paulo JA, Huttlin EL, Frohlich F, Gygi SP,
            Van Vactor D and Harper JW.
  TITLE     QIL1 is a novel mitochondrial protein required for MICOS complex
            stability and cristae morphology
  JOURNAL   Elife 4, e06265 (2015)
   PUBMED   25997101
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 906)
  AUTHORS   Ott C, Dorsch E, Fraunholz M, Straub S and Kozjak-Pavlovic V.
  TITLE     Detailed analysis of the human mitochondrial contact site complex
            indicate a hierarchy of subunits
  JOURNAL   PLoS One 10 (3), e0120213 (2015)
   PUBMED   25781180
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 906)
  AUTHORS   Turkieh,A., Caubere,C., Barutaut,M., Desmoulin,F., Harmancey,R.,
            Galinier,M., Berry,M., Dambrin,C., Polidori,C., Casteilla,L.,
            Koukoui,F., Rouet,P. and Smih,F.
  TITLE     Apolipoprotein O is mitochondrial and promotes lipotoxicity in
            heart
  JOURNAL   J Clin Invest 124 (5), 2277-2286 (2014)
   PUBMED   24743151
REFERENCE   5  (bases 1 to 906)
  AUTHORS   Zerbes RM, van der Klei IJ, Veenhuis M, Pfanner N, van der Laan M
            and Bohnert M.
  TITLE     Mitofilin complexes: conserved organizers of mitochondrial membrane
            architecture
  JOURNAL   Biol Chem 393 (11), 1247-1261 (2012)
   PUBMED   23109542
  REMARK    Review article
REFERENCE   6  (bases 1 to 906)
  AUTHORS   Zhao X, Leon IR, Bak S, Mogensen M, Wrzesinski K, Hojlund K and
            Jensen ON.
  TITLE     Phosphoproteome analysis of functional mitochondria isolated from
            resting human muscle reveals extensive phosphorylation of inner
            membrane protein complexes and enzymes
  JOURNAL   Mol Cell Proteomics 10 (1), M110.000299 (2011)
   PUBMED   20833797
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM122174.1, DV726817.1 and CB616794.1.
            
            On or before Nov 25, 2010 this sequence version replaced
            XM_002727568.1, XM_343793.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ210589.1, FQ221097.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-607               FM122174.1         1-607
            608-887             DV726817.1         280-559
            888-906             CB616794.1         26-44               c
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq22"
     gene            1..906
                     /gene="Apoo"
                     /gene_synonym="RGD1565289"
                     /note="apolipoprotein O"
                     /db_xref="GeneID:363474"
                     /db_xref="RGD:1565289"
     exon            1..23
                     /gene="Apoo"
                     /gene_synonym="RGD1565289"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..611
                     /gene="Apoo"
                     /gene_synonym="RGD1565289"
                     /codon_start=1
                     /product="MICOS complex subunit MIC26"
                     /protein_id="NP_001186107.1"
                     /db_xref="GeneID:363474"
                     /db_xref="RGD:1565289"
                     /translation="MFKVIQRSVGPASLSLLTFRVYAAPKKDSPHKSYMKIDELSLYS
                     VPEGQSKYVEEPRTQLEENISELRHRCEPYTNLCQEIYSHTKPKVEHFVQWGVDNYNY
                     LQNAPPGFYPRLGVIGFAGFVGLLFARGSKIKKLVYPPFFMGLGASVYYPQQAITIAQ
                     ITGEKLYDWGLRGYIVVEDLWKQHFQKPGNVKSSPGNK"
     exon            24..131
                     /gene="Apoo"
                     /gene_synonym="RGD1565289"
                     /inference="alignment:Splign:2.1.0"
     exon            132..251
                     /gene="Apoo"
                     /gene_synonym="RGD1565289"
                     /inference="alignment:Splign:2.1.0"
     exon            252..306
                     /gene="Apoo"
                     /gene_synonym="RGD1565289"
                     /inference="alignment:Splign:2.1.0"
     exon            307..402
                     /gene="Apoo"
                     /gene_synonym="RGD1565289"
                     /inference="alignment:Splign:2.1.0"
     exon            403..494
                     /gene="Apoo"
                     /gene_synonym="RGD1565289"
                     /inference="alignment:Splign:2.1.0"
     exon            495..575
                     /gene="Apoo"
                     /gene_synonym="RGD1565289"
                     /inference="alignment:Splign:2.1.0"
     exon            576..641
                     /gene="Apoo"
                     /gene_synonym="RGD1565289"
                     /inference="alignment:Splign:2.1.0"
     exon            642..890
                     /gene="Apoo"
                     /gene_synonym="RGD1565289"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggctgccag cgacatgttc aaggtaattc agagatctgt ggggccagcc agcctgagcc
       61 tgctcacctt cagagtttat gcagcaccca aaaaggactc gcctcacaaa agttacatga
      121 agatcgatga gctctcactc tactcagttc ctgagggtca atctaaatat gtggaggagc
      181 caaggactca acttgaagaa aacatctcag aactccgaca tcgttgtgag ccatatacaa
      241 atttgtgtca ggaaatatac tcccatacta aacccaaggt ggaacacttt gtccagtggg
      301 gagtagacaa ctataactat cttcaaaatg cacctcctgg attttaccca agactcggag
      361 ttattggttt tgctggtttt gttggactcc tttttgctag aggttcaaaa ataaagaagc
      421 tggtgtatcc tcctttcttc atggggttag gtgcctctgt ctattaccca caacaagcca
      481 tcactattgc ccagatcact ggggagaagt tatatgactg gggattacga gggtacatag
      541 ttgtagaaga tttgtggaag caacattttc agaagccagg aaatgtgaag agttcacctg
      601 gaaataaata gaaaactcta cgctctaccc attataatca gttataggta aacattggaa
      661 actccagaca gtaactcagt atttctacag acaaatggca gaatcagtat tggatatagt
      721 aaactggctt tcatcaggaa aaacattaag cctttttgct ggtttgggtg atgccatatt
      781 acaggccaac taatctgcaa tctttcacgt ggaaataatg tacaagcctt agaactcctc
      841 attcttatat cactatttat gtatataatt aaagtccaga ttccaacaaa aaaaaaaaaa
      901 aaaaaa
//
