LOCUS       NM_001003403            2925 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus apolipoprotein L domain containing 1 (Apold1),
            mRNA.
ACCESSION   NM_001003403 XM_579097
VERSION     NM_001003403.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2925)
  AUTHORS   Regard,J.B., Scheek,S., Borbiev,T., Lanahan,A.A., Schneider,A.,
            Demetriades,A.M., Hiemisch,H., Barnes,C.A., Verin,A.D. and
            Worley,P.F.
  TITLE     Verge: a novel vascular early response gene
  JOURNAL   J Neurosci 24 (16), 4092-4103 (2004)
   PUBMED   15102925
  REMARK    GeneRIF: We describe a novel immediate early gene that is expressed
            selectively in vascular endothelial cells. These studies suggest
            that Verge functions as a dynamic regulator of endothelial cell
            signaling and vascular function. [Verge]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Dec 2, 2020 this sequence version replaced NM_001003403.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.2031839.1,
                                           SRR26643294.19953.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-39                JAXUCZ010000004.1  169552599-169552637
            40-2925             JAXUCZ010000004.1  169554190-169557075
FEATURES             Location/Qualifiers
     source          1..2925
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q43"
     gene            1..2925
                     /gene="Apold1"
                     /gene_synonym="Verge"
                     /note="apolipoprotein L domain containing 1"
                     /db_xref="GeneID:444983"
                     /db_xref="RGD:1303123"
     exon            1..39
                     /gene="Apold1"
                     /gene_synonym="Verge"
                     /inference="alignment:Splign:2.1.0"
     exon            40..2925
                     /gene="Apold1"
                     /gene_synonym="Verge"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..783
                     /gene="Apold1"
                     /gene_synonym="Verge"
                     /note="vascular early response gene protein"
                     /codon_start=1
                     /product="apolipoprotein L domain-containing protein 1"
                     /protein_id="NP_001003403.1"
                     /db_xref="GeneID:444983"
                     /db_xref="RGD:1303123"
                     /translation="MEKWTAWEPQGADALRRFQGLLLDRRGRLHCQVLRLREVARRLE
                     RLRRRSLAANVAGSSLSAAGALAAIVGLSLSPVTLGASLVASAVGLGVATAGGAVTIT
                     SDLSLIFCNSREVRRVQEIAATCQDQMRELLSCLEFFCQWQGRGDRQLLQSGRDASMA
                     LYNSVYFIVFFGSRGFLIPRRAEGATKVSQAVLKAKIQKLSESLESCTGALDELSEQL
                     ESRVQLCTKAGRGHNLRNSPDLDAALFF"
ORIGIN      
        1 acagtctccc actttgcttc ctggaggcca gagtgaaggg gcatggagaa gtggacggcc
       61 tgggagccgc agggcgccga tgcgctgcgg cgctttcaag ggttgctgct ggaccgccgc
      121 ggccggctgc actgccaagt gttgcgcctg cgcgaagtgg cccggaggct cgagcgtcta
      181 cggaggcgct ccttggcagc caacgtagct ggcagctctc tgagcgctgc tggcgcccta
      241 gcagccatcg tggggttatc actcagcccg gtcaccctgg gagcctcgct cgtggcgtcc
      301 gccgtgggct taggggtggc caccgccgga ggggcagtca ccatcacgtc cgacctctct
      361 ctgatcttct gcaattcccg ggaggtacgg agggtgcaag agatcgccgc cacctgccag
      421 gaccagatgc gcgaactcct gagctgcctt gagttcttct gtcagtggca ggggcgcggg
      481 gaccgccagc tgctgcagag cgggagggac gcctccatgg ctctttacaa ctctgtctac
      541 ttcatcgtct tcttcggctc gcgtggcttc ctcatcccca ggcgtgcgga gggggccacc
      601 aaagtcagcc aggccgtgct gaaggccaag attcagaaac tgtctgagag cctggagtcc
      661 tgcactggtg ccctggatga acttagtgag cagctggaat cccgggtcca gctctgtacc
      721 aaggccggcc gtggtcacaa cctcaggaac tcccctgatc tggatgcagc gttgtttttc
      781 taagagcatc ctctagctgt gtggaatgtt ctagattcgc agcatccaca aggaagtgct
      841 acatgggcgg agtgcaaagg atttcagaag ctcttcttgc agggcatcag tccgtagctc
      901 cttgtgtgtg cgaaagactt ttcacttgtg taatcccaac tgagtatgtg accctaaaca
      961 gtcactttgg ggactcccca aatccttttt agctgcacac agcttgtcag actgtccttc
     1021 aattagagtt attggggtgg gggggcttga tggcttgagt aatagaggtc tggcgaggtg
     1081 tctccctctt ggacctctta tgtgttgtta ctagaatcct gagattctca aatgttggtg
     1141 agaggagact tttacttttc aactttgctt cggcagtttc cgatacacag gactccagaa
     1201 tccagaacaa gaaagaagaa ccttgtgttt gtagggtgtg cagacccaga cggggccgag
     1261 gagctgactt gctcagctct cacacgcagc cagtttatcc actcacagac caaacctggc
     1321 tactgcatag actgttccag tgtggcttca aatccacacc tctaggtacc ctgagaagga
     1381 aagccacctg aagagtcact ctaatcccaa cacgctcacc cccttcacgt ccataaagga
     1441 gctgggcaag gggtgagatg aagaccctga caattttaaa tgactgtagc atagagagcc
     1501 atggcctttg agtttaagag tcttgatccc aggttctgtc ccccactgtc ctgtgactta
     1561 gccaccttgt cttgctacag atggtggtag gaggccaccc tgttgcgaag tcctgagata
     1621 atgacaaaca cagaggctag ctcacaaaaa tgtacttcct ggcctggctt ctgaagggtt
     1681 aactgttggg ctccatccca gatttctgag atcaggaact ccaaatatga ggcccgcctc
     1741 tggctgattc tgatgcccca taaatgtttg aaaatgacac agcaaaggtt catctccagc
     1801 caggtgtggt gggacacacc tgtaaggcca gcgcttggag atggagacag ggggaccagt
     1861 agttcagggt cattcttggc tacatagcaa actcaaggcc accctggtct caaaaaccaa
     1921 aacaaaaagc catcttctga ctcccttcaa ttgttcaaag cctttccagg gccttcagaa
     1981 tcacgctcag agtgttctgg gaagattagc ccagaagcca gagaaagagt acgctgtgtg
     2041 cttgtaaagc cagttactct gtcccctgtg aactaggaga cagagcactt ccgaccctat
     2101 agagggcagt agtggccatt ccttgtaggg gactggtata gaagtaatgt gaactattta
     2161 aaaatagtta tttaattgct gccttcacat ttgattttat ttaaccttca cattatttag
     2221 aaaataataa gagtagtaag tgtctgaata ggaagggagt ctcttaaggc tctttccaag
     2281 agctcaggtt tggatttcta gagtcccccc gaccccagag aggactcttt agtgtttgac
     2341 acggtctttg taagtaagat ggggagtcct ggagagagag accaagctga tttttaaact
     2401 aggaaatgga gtcttgaact gtggaagatt tgaaaagtta agcctatgtg tcttgaaggt
     2461 acttggccag aaaagcactt ggcttgaaaa agaaaacctg tttaattcag gggtggagga
     2521 atagagacag atgaagaaag catttagacc tcggaaacct gatgtcctat gaaattctgt
     2581 ttttataaaa ttgtgttatg gtggagatct gttgcatttc gactttgtgg ctgtaagaaa
     2641 cctgttatct atgtttaaga aagtacttct aatttattca atgtcttcct aaattatcct
     2701 ttaaaaaaaa aagttggaaa gtctatgaga ccgtacctaa gaaaccttga ctgtgtattt
     2761 aagttattta atgccatgca tttgtgaagc cccttcccag tgatggctgt ggtgtgtctg
     2821 aggaaatgta agtttggcat gagggggagg ggctgctgtt tctatatttg tttttgtttt
     2881 ctataaacag taatcaggat gtatcctggt ttcatttgac attga
//
