LOCUS       NM_001109419             470 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus apolipoprotein C4 (Apoc4), mRNA.
ACCESSION   NM_001109419 XM_001057696
VERSION     NM_001109419.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Wang,X., Gong,Y., Deng,T., Zhang,L., Liao,X., Han,C., Yang,C.,
            Huang,J., Wang,Q., Song,X., Zhang,T., Yu,T., Zhu,G., Ye,X. and
            Peng,T.
  TITLE     Diagnostic and prognostic significance of mRNA expressions of
            apolipoprotein A and C family genes in hepatitis B virus-related
            hepatocellular carcinoma
  JOURNAL   J Cell Biochem 120 (10), 18246-18265 (2019)
   PUBMED   31211449
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Kim,E., Li,K., Lieu,C., Tong,S., Kawai,S., Fukutomi,T., Zhou,Y.,
            Wands,J. and Li,J.
  TITLE     Expression of apolipoprotein C-IV is regulated by Ku
            antigen/peroxisome proliferator-activated receptor gamma complex
            and correlates with liver steatosis
  JOURNAL   J Hepatol 49 (5), 787-798 (2008)
   PUBMED   18809223
REFERENCE   3  (bases 1 to 470)
  AUTHORS   Mancone,C., Amicone,L., Fimia,G.M., Bravo,E., Piacentini,M.,
            Tripodi,M. and Alonzi,T.
  TITLE     Proteomic analysis of human very low-density lipoprotein by
            two-dimensional gel electrophoresis and MALDI-TOF/TOF
  JOURNAL   Proteomics 7 (1), 143-154 (2007)
   PUBMED   17154273
REFERENCE   4  (bases 1 to 470)
  AUTHORS   Kotite,L., Zhang,L.H., Yu,Z., Burlingame,A.L. and Havel,R.J.
  TITLE     Human apoC-IV: isolation, characterization, and immunochemical
            quantification in plasma and plasma lipoproteins
  JOURNAL   J Lipid Res 44 (7), 1387-1394 (2003)
   PUBMED   12700345
REFERENCE   5  (bases 1 to 470)
  AUTHORS   Allan,C.M. and Taylor,J.M.
  TITLE     Expression of a novel human apolipoprotein (apoC-IV) causes
            hypertriglyceridemia in transgenic mice
  JOURNAL   J Lipid Res 37 (7), 1510-1518 (1996)
   PUBMED   8827523
REFERENCE   6  (bases 1 to 470)
  AUTHORS   Shen,P. and Howlett,G.J.
  TITLE     Two coding regions closely linked to the rat apolipoprotein E gene:
            nucleotide sequences of rat apolipoprotein C-I and ECL cDNA
  JOURNAL   Arch Biochem Biophys 297 (2), 345-353 (1992)
   PUBMED   1379790
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            On Oct 4, 2007 this sequence version replaced XM_001057696.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ218092.1, FQ218144.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..470
                     /gene="Apoc4"
                     /gene_synonym="Acl"
                     /note="apolipoprotein C4"
                     /db_xref="GeneID:680551"
                     /db_xref="RGD:70959"
     exon            1..116
                     /gene="Apoc4"
                     /gene_synonym="Acl"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..415
                     /gene="Apoc4"
                     /gene_synonym="Acl"
                     /note="ECL; apo-CIV; apoC-IV; apolipoprotein E-linked;
                     apolipoprotein C-IV; apolipoprotein C2 linked;
                     apolipoprotein CIV"
                     /codon_start=1
                     /product="apolipoprotein C-IV precursor"
                     /protein_id="NP_001102889.1"
                     /db_xref="GeneID:680551"
                     /db_xref="RGD:70959"
                     /translation="MSLLRCRQQTLPSLCLSVLFLACFVASMPTESLTPTPGPENSRW
                     SLVRARVMEMVEPLVTRTRDRWRWFWGPRAIQGFVQTYYEDHLKDLGPRTQAWLQSSR
                     DHLLNKTHSLCPRLLCRDWTQG"
     exon            117..249
                     /gene="Apoc4"
                     /gene_synonym="Acl"
                     /inference="alignment:Splign:2.1.0"
     exon            250..470
                     /gene="Apoc4"
                     /gene_synonym="Acl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtacagaggg acagagacac agaggcccaa gtccccagaa atgtccctgc tgagatgcag
       61 gcagcagacc ctgccatcac tctgcctctc tgtgctgttc ctggcctgct ttgtagcatc
      121 catgcctaca gaaagcttga cccccactcc tggccctgag aacagccgct ggagcctggt
      181 aagagccagg gtgatggaga tggtggaacc actggtgacc agaaccaggg acagatggcg
      241 gtggttctgg ggccccagag ctatccaggg cttcgtgcag acctactatg aagatcacct
      301 gaaagacctg ggtccccgaa ctcaggcctg gctgcagagc tccagagacc acctcctaaa
      361 caagacccac agcctgtgtc ccagactgct ctgcagggac tggactcagg gttaaagtgc
      421 caccacgtac ctccctcccc tggaacccac aataaaggtg tttgttcttg
//
