LOCUS       NM_001106883            1198 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus apolipoprotein B mRNA editing enzyme catalytic
            subunit 2 (Apobec2), mRNA.
ACCESSION   NM_001106883 XM_001063358 XM_217334
VERSION     NM_001106883.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1198)
  AUTHORS   Guo JU, Su Y, Zhong C, Ming GL and Song H.
  TITLE     Hydroxylation of 5-methylcytosine by TET1 promotes active DNA
            demethylation in the adult brain
  JOURNAL   Cell 145 (3), 423-434 (2011)
   PUBMED   21496894
REFERENCE   2  (bases 1 to 1198)
  AUTHORS   Prochnow C, Bransteitter R, Klein MG, Goodman MF and Chen XS.
  TITLE     The APOBEC-2 crystal structure and functional implications for the
            deaminase AID
  JOURNAL   Nature 445 (7126), 447-451 (2007)
   PUBMED   17187054
REFERENCE   3  (bases 1 to 1198)
  AUTHORS   Liao W, Hong SH, Chan BH, Rudolph FB, Clark SC and Chan L.
  TITLE     APOBEC-2, a cardiac- and skeletal muscle-specific member of the
            cytidine deaminase supergene family
  JOURNAL   Biochem Biophys Res Commun 260 (2), 398-404 (1999)
   PUBMED   10403781
REFERENCE   4  (bases 1 to 1198)
  AUTHORS   Hirano K, Young SG, Farese RV Jr, Ng J, Sande E, Warburton C,
            Powell-Braxton LM and Davidson NO.
  TITLE     Targeted disruption of the mouse apobec-1 gene abolishes
            apolipoprotein B mRNA editing and eliminates apolipoprotein B48
  JOURNAL   J Biol Chem 271 (17), 9887-9890 (1996)
   PUBMED   8626621
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473987.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001063358.1, XM_217334.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ214885.1, FQ215260.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1198
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q12"
     gene            1..1198
                     /gene="Apobec2"
                     /note="apolipoprotein B mRNA editing enzyme catalytic
                     subunit 2"
                     /db_xref="GeneID:301226"
                     /db_xref="RGD:1308727"
     exon            1..254
                     /gene="Apobec2"
                     /inference="alignment:Splign:2.1.0"
     CDS             124..798
                     /gene="Apobec2"
                     /EC_number="3.5.4.36"
                     /note="probable C->U-editing enzyme APOBEC-2;
                     apolipoprotein B editing complex 2; apolipoprotein B mRNA
                     editing enzyme, catalytic polypeptide-like 2"
                     /codon_start=1
                     /product="C->U-editing enzyme APOBEC-2"
                     /protein_id="NP_001100353.1"
                     /db_xref="GeneID:301226"
                     /db_xref="RGD:1308727"
                     /translation="MAQKEEAAEAAAPASQNGDDLENLEDPEKLKELIDLPPFEIVTG
                     VRLPVNFFKFQFRNVEYSSGRNKTFLCYVVEAQSKGGQVQATQGYLEDEHAGAHAEEA
                     FFNTILPAFDPALKYNVTWYVSSSPCAACADRILKTLSKTKNLRLLILVSRLFMWEEP
                     EVQAALKKLKEAGCKLRIMKPQDFEYLWQNFVEQEEGESKAFEPWEDIQENFLYYEEK
                     LADILK"
     exon            255..818
                     /gene="Apobec2"
                     /inference="alignment:Splign:2.1.0"
     exon            819..1198
                     /gene="Apobec2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caaacctggt cctctttctg tcatccccag ccaggcttag ctgctgacag ctgcttggga
       61 ctctgcctcc aggcccttgg ctggcttggc aacctctcca cctctcccag tcacagctcc
      121 tccatggctc agaaggaaga agccgctgag gccgcggcac cagcctctca gaacggagac
      181 gatttggaga acctagaaga ccctgagaag ctgaaggagc tgatcgatct gccgcccttc
      241 gagatcgtca ctggggtgcg actgcctgtc aacttcttta agtttcagtt ccggaacgtg
      301 gaatacagtt ccgggcggaa caagaccttt ctctgctatg tggtcgaagc acagagcaag
      361 ggaggccaag tgcaggcgac gcagggctac ctggaggatg aacacgctgg tgcccacgct
      421 gaggaggctt tctttaacac catcctgcca gctttcgacc cggccctgaa gtataatgtc
      481 acctggtatg tgtcctccag cccctgtgca gcctgcgccg accgaattct caagaccctc
      541 agcaagacca agaacctgcg gctgctcatc ctggtgagcc ggctcttcat gtgggaggag
      601 ccagaggtcc aggccgccct gaagaagctg aaggaggcgg gctgcaaact tcgcatcatg
      661 aaaccccagg acttcgagta cctctggcag aattttgtgg agcaagaaga gggtgaatcc
      721 aaggcctttg agccctggga ggacattcag gagaacttcc tatactatga ggagaagttg
      781 gcagacatcc tgaagtaggc aacagagctc agccttccgt ctgcctgctg ccactcagag
      841 caatgaccag gatggcatcc gggacatgcc tggcttcctg attctacttg gagttggaca
      901 tctgatacct accattacct cccctcagag aactcaaaac acatctcagg ccatcattca
      961 ttcagccatg ccttccaaca tggctcttgg aagaaaggaa aatgaagaca agaaaaacgt
     1021 gtgatgtggg cagcaggtac ctgggggtgg agggtcttgt tgcctctcca ggggtgctgc
     1081 ctgagacaga gattcatagt caaggtttga cctcaaaata catctagaaa agtgttttga
     1141 attgagctgg ctttttaaaa gacaaaatag caacatcaat aaaggaaata gcgttttt
//
