LOCUS       NM_019287              14091 bp    mRNA    linear   ROD 09-JAN-2024
DEFINITION  Rattus norvegicus apolipoprotein B (Apob), mRNA.
ACCESSION   NM_019287 XM_343035
VERSION     NM_019287.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 14091)
  AUTHORS   Bian X, Gao W, Wang Y, Yao Z, Xu Q, Guo C and Li B.
  TITLE     Riboflavin deficiency affects lipid metabolism partly by reducing
            apolipoprotein B100 synthesis in rats
  JOURNAL   J Nutr Biochem 70, 75-81 (2019)
   PUBMED   31176989
  REMARK    GeneRIF: Riboflavin deficiency affects lipid metabolism partly by
            reducing apolipoprotein B100 synthesis in rats.
REFERENCE   2  (bases 1 to 14091)
  AUTHORS   Liu M, Chung S, Shelness GS and Parks JS.
  TITLE     Hepatic ABCA1 deficiency is associated with delayed apolipoprotein
            B secretory trafficking and augmented VLDL triglyceride secretion
  JOURNAL   Biochim Biophys Acta Mol Cell Biol Lipids 1862 (10 Pt A), 1035-1043
            (2017)
   PUBMED   28694219
  REMARK    GeneRIF: enhanced VLDL TG secretion in the absence of hepatocyte
            ABCA1 is due to altered intracellular trafficking of apolipoprotein
            B (apoB), resulting in augmented TG addition to nascent VLDL.
REFERENCE   3  (bases 1 to 14091)
  AUTHORS   Shahid SU, Shabana, Cooper JA, Beaney KE, Li K, Rehman A and
            Humphries SE.
  TITLE     Genetic risk analysis of coronary artery disease in Pakistani
            subjects using a genetic risk score of 21 variants
  JOURNAL   Atherosclerosis 258, 1-7 (2017)
   PUBMED   28167353
REFERENCE   4  (bases 1 to 14091)
  AUTHORS   Corsetti JP, Gansevoort RT, Bakker SJL and Dullaart RPF.
  TITLE     Apolipoprotein E levels and apolipoprotein E genotypes in incident
            cardiovascular disease risk in subjects of the Prevention of Renal
            and Vascular End-stage disease study
  JOURNAL   J Clin Lipidol 10 (4), 842-850 (2016)
   PUBMED   27578115
REFERENCE   5  (bases 1 to 14091)
  AUTHORS   Patterson AP, Chen Z, Rubin DC, Moucadel V, Iovanna JL, Brewer HB
            Jr and Eggerman TL.
  TITLE     Developmental regulation of apolipoprotein B mRNA editing is an
            autonomous function of small intestine involving homeobox gene Cdx1
  JOURNAL   J Biol Chem 278 (9), 7600-7606 (2003)
   PUBMED   12493769
  REMARK    GeneRIF: the developmental regulation of apoB mRNA editing is an
            autonomous cytodifferentiation function of small intestine and
            involves Cdx1
REFERENCE   6  (bases 1 to 14091)
  AUTHORS   al Muhtaseb N, al Yousuf A and Bajaj JS.
  TITLE     Apolipoprotein A-I, A-II, B, C-II, and C-III in children with
            insulin-dependent diabetes mellitus
  JOURNAL   Pediatrics 89 (5 Pt 1), 936-941 (1992)
   PUBMED   1579407
REFERENCE   7  (bases 1 to 14091)
  AUTHORS   Helio T, Palotie A, Totterman KJ, Ott J, Kauppinen-Makelin R and
            Tikkanen MJ.
  TITLE     Lack of association between the apolipoprotein B gene 3'
            hypervariable region alleles and coronary artery disease in Finnish
            patients with angiographically documented coronary artery disease
  JOURNAL   J Intern Med 231 (1), 49-57 (1992)
   PUBMED   1732399
REFERENCE   8  (bases 1 to 14091)
  AUTHORS   Sehayek E and Eisenberg S.
  TITLE     Mechanisms of inhibition by apolipoprotein C of apolipoprotein
            E-dependent cellular metabolism of human triglyceride-rich
            lipoproteins through the low density lipoprotein receptor pathway
  JOURNAL   J Biol Chem 266 (27), 18259-18267 (1991)
   PUBMED   1917954
REFERENCE   9  (bases 1 to 14091)
  AUTHORS   Konemori G, Kawanishi M, Nakamoto A, Hiraoka M and Kajiyama G.
  TITLE     [Application of the box plot to evaluate serum lipid levels and
            apolipoprotein levels in patients with cerebral infarction and
            diabetes mellitus]
  JOURNAL   Nihon Ronen Igakkai Zasshi 27 (1), 22-27 (1990)
   PUBMED   2352345
REFERENCE   10 (bases 1 to 14091)
  AUTHORS   Tennyson GE, Sabatos CA, Higuchi K, Meglin N and Brewer HB Jr.
  TITLE     Expression of apolipoprotein B mRNAs encoding higher- and
            lower-molecular weight isoproteins in rat liver and intestine
  JOURNAL   Proc Natl Acad Sci U S A 86 (2), 500-504 (1989)
   PUBMED   2911593
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1989 Apr;86(8):2657]
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CB694353.1, CB801343.1,
            AY318958.1, CB771776.1, BC098761.1, AA997806.1 and CV796295.1.
            
            On Dec 5, 2007 this sequence version replaced NM_019287.1.
            
            Summary: This gene product is the main apolipoprotein of
            chylomicrons and low density lipoproteins. It occurs in plasma as
            two main isoforms, apoB-L and apoB-H. Unlike the apoB-48 and
            apoB-100 structural equivalents in human, which are synthesized
            exclusively in the gut and liver, respectively, the rat apoBL
            isoform is also found in rat liver. The intestinal and the hepatic
            forms of apoB are encoded by a single gene from a single, very long
            mRNA. The two isoforms share a common N-terminal sequence. The
            shorter apoB-L protein is produced after RNA editing of the apoB-H
            transcript at residue 2180 (CAA->UAA), resulting in the creation of
            a stop codon, and early translation termination. [provided by
            RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5756307,
                              SAMEA5760393 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            undergoes RNA editing  :: PMID: 12493769, 2911593
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-230               CB694353.1         18-247
            231-422             CB801343.1         223-414
            423-3819            AY318958.1         304-3700
            3820-3965           CB771776.1         62-207
            3966-13590          AY318958.1         3787-13411
            13591-13941         BC098761.1         1264-1614
            13942-14062         AA997806.1         29-149              c
            14063-14091         CV796295.1         1-29                c
FEATURES             Location/Qualifiers
     source          1..14091
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q14"
     gene            1..14091
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /note="apolipoprotein B"
                     /db_xref="GeneID:54225"
                     /db_xref="RGD:2129"
     exon            1..202
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     CDS             121..13641
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /note="apolipoprotein B-100; apolipoprotein B-48;
                     apolipoprotein B PI; apolipoprotein B (including Ag(x)
                     antigen)"
                     /codon_start=1
                     /product="apolipoprotein B-100 precursor"
                     /protein_id="NP_062160.2"
                     /db_xref="GeneID:54225"
                     /db_xref="RGD:2129"
                     /translation="MGPQRPALRAPLLLLFLLLFLDTSVWAQDEVLENFILNCPKDAT
                     RFKHLRKYVYSYEAESSSGVRGTADSRSATKINCKVELEVPQVCTLIMRTSQCTLKEV
                     YGFNPEGKALMKKTKNSEEFASAMSRYELKLAFPEGKRVALYPDLGEPNYILNIKRGI
                     ISALLVPPETEEDKQVLFQDTVYGNCSTQVTVNSRKGTVATEMSTERNLQHCDGFQPI
                     STSVSPLALIKGLVRPLSTLISSSQSCQYTLEPKRKHVSEAICNEQHLFLPFSYKNKY
                     GIMTHVTQKLSLEDTPKINSRFFRGGINQVGLAFESTKSTSPPKQADAVLKTLQELKK
                     LSISEQNAQRANLFHKLVTELRGLSGEAITSLLPQLIEVSSPITLQALIQCGQPECYT
                     HILQWLKTEKAHPLLIDIVTYLMALIPNPSVQRLQEIFNTAKELQSRATLYALSHAVN
                     SYYAIMDHSRSPVLEDIAGYLMKQIDNECMGDEDRTFLILRVIGNMGRTMERVMPALK
                     SSVLNCVRSTKPSLQIQKAALQALRKMEMGDEVRTILFDTFVNDVAPVEKRLAAYLLL
                     MRSPSSSDINKIAKLLQWEQSEQVKNFVASHIANILNSEELYVQDLKNLIKNALVNSR
                     LPTIMDFRKFSRNYQISKSVSIPLFDPVSAKIEGNLVFDPSSYLPKESMLKTTLTVFG
                     IASLDLFEIGLEGKGFEPTLEALFGKQGFFPDSVNKALYWVNGQVPDRVSKVLVDHFG
                     YTKDDKHEQDMVNGIMPIVDKLIKELKSKEIPEARAYLRILGKELGFVRLQDLQVLGK
                     LLLNGAQTFRGVPQMIVQAIREGSKDDLFLHYIFMENAFELPTGVGLQLQVSSSGVFT
                     PGIKAGVRLELANIQAELVAKPSVSLEFVTNMGIIIPDFAKSGVQMNTNFFHESGLEA
                     RVALKAGQLKVIIPSPKRPVKLFSGSNTLHLVSTTKTEVIPPLIENRKSWSTCKPFFT
                     GMNYCTTGAYSNASSTESASYYPLTGDTRYELELKPTGEVEQYSASATYELLKEDKSL
                     VDTLKFLVQAEGVQQSEATAMFKYNRRSRTLSSEVLIPGFDVNFGTILRVNDESSKDK
                     NTYKLILDIQNKKITEVSVVGHVSYDKKGDGKVKGVVSIPRLQAEARSEVHTHWSPTK
                     LLFQMDSSATAYGSTISKRVAWRYDNEKIEFDWNTGTNVDTKKVASNFPVDLSRYPRM
                     VHEYANGLLDHRVPQTDMTFRHMGSKLIVATNTWLQMATRGLPYPQSLQDHLNGLSEL
                     NLPKVGLPDFHIPDNLFLKTDGRVKYTLNKNRIEIDIPLPLGGKSSKDLKVPESVRTP
                     ALNFKSVGFHLPSQEVQIPTFTIPKTHQLQVPLLGILDLSTNVYSNLYNWSVSYTGGN
                     TSRDHFSLQAQYRMKADSVVDLFSYSVQGSGETTYDSKSTFTLSCDGSLHHKFLDSKF
                     KVSHVEKFGNNPVSKGLLTFETSSALGPQMSATVQLDSKKKQHLYVKDIKVDGQFRVF
                     SLYAQGEYGLSYERDSMTGQMSGESNMKFNSTYFQGTNQIVGMYQDGMLSVTSTSDLQ
                     DGIFKNTASLKYENYELTLKSDSSGQYENFAASNKLDMTFSKQSALLRSEHQANYKSL
                     RLVTLLSGSLTSQGVELNADILGTDKINTGAHKSTLKIAQDGVSTSATTNLKYSPLLL
                     ENELNAELGLSGASMKLSTSGRFKEHHAKFSLDGRAALTEVSLGSIYQAMILGADSKN
                     VFNFKLSREGLKLSNDMMGSYAEMKLDHTHSLRISGLSLDFFSKMDNIYSGDKFYKQN
                     FNLQLQPYSFGITLSNDLKYDALVLTNNGRLRLEPLKLNVGGNFKGTYQNNELKHIYT
                     ISYTDLVVASYRADTVATVQGVEFSHRLNADIEGLASSVDVTTSYSSDPLHFNNVFRF
                     VLAPFTLGVDTHTSGDGKMSLWGEHTGQMYSKFLLKAEPLALTFSHDYKGSTSHNLLY
                     KNSVSTALEHTLSALLTPAEQTSSWKFKTSLNDKVYSQEFEAYNTKDKIGIELSGRAD
                     LSGLYSPIKVPFFYSEPVNVLNSLEINDAFDEPREFTIDAVVKYDKNQDVHTISLPFF
                     QSLPDYLERNRRGIISLLEAMKGELQRLSVDQFVRKYRVALSRLPQQIHDYLNASDWE
                     RQVAGAKEKLTSFMENYRITDNDVLIALDSAKINLNEKLSQLETYAIQFDQYIRDNYD
                     AQDLKRTIAQIIDRIIEKLKMLDEQYHIRVNLAKSIHNLYLFVENVDLNQISSSGASW
                     IQNVDTKYQIRIQIQEKLQHLRTQIHNIDIQQLAAELKQQIEALDVPMHLDQLRTAIL
                     FQRISVIIERVKYFVMNLIEDFKVTEKINTFRVIVRELIEKYEVDRQIQVLMDKSIEL
                     AHRYSLSEPLQKLSNVLQQIEIKDYYDKLVGFIDDTVEWIKAVSFKNIIEELNRLIDM
                     SVKKLKAFDYHQFVDKTNSKIREMTQRINAEIQALELPQKTEALKLWVEDFKTTVSNS
                     LEKLKDTKVTVVVDWLQDGLAQIKAQFQDALEDVRDRIYQMDIQGELERCLSLVSQVY
                     STVVTYISDWWTLTAKNITDFAEQYSTQKWAESVKALVEQGFIVPEIQTFLGTMPAFE
                     VSLHALQEANFQTPDFIVPLTDLRIPSIWINFKMLKNVKIPLRFSTPEFTLLNTFRVR
                     SFTIDLLEIKAKIIRTIDQMLSSELQWPLPEVYLRDLEMVNISLARLSLPDFHVPEIT
                     IPEFTIPNVNLKDLQVPDLHIPEFQLPHLSCTTEIPAFGKLHSVLKIQSPLFILDASA
                     NIQNITTSENKAEIVASVTARGESKFEALNFDFQAQAQFLELNANPLVLKESVNFSSK
                     HVRMEHEGKILVSGKALEGKSDTVARLHTEKNTVEFNNGIVVKINNQFTLDSQTKYFH
                     KLSVPRLDFSSKASLNNEIKTLLEAGHMAWTSSGTGSWNWACPNFSDEGIHSSKISFI
                     VDGPIASFGLSNNINGKHLRVVQKLTSESGFLNYSRFEVESKVESQHVGSSILTAEGR
                     ALLGDAKAEMTGEHNANLNGKVIGTLKNSLFFSAQPFEITASTNNEGNLKVSFPLKLT
                     GKIDFLNNYALFLSPHAQQASWQLSTRFNQYKYNQNFSAINNEHNMEASIVMNGDANL
                     DFLNIPLTIPEINLPYTRFTTPLLKDFSIWEETGLKEFLKTTKQSFDLSIKAQYKKNR
                     DKHSVVIPLKMFYEFMLNNVNSWDRKFEKVRDNALHFLTASYNETKIKFDKYKTENSL
                     NQPSRTFQNRGHTIPVLNIEVSPFAVETLASSHVIPKAIRTPSVTIPGPNIIVPSYRL
                     VLPSLQLPVFHIPRTLFKFSLPDFKKLSTIDNIYIPAMGNFTYDFSFKSSVITLNTNA
                     GLYNQSDLVARFLSSSSFVTDALQYKLEGTSRLMRKKVLKLATAVSLTNKFLKGSHDS
                     TISLTKKNMEASVKTTANLHAPIFTMNFKQELNGNTKSKPTVSSSIELNYDFNSSKLH
                     SAAKGGVDHKFSLESLTSYLSIESFTKGNIKGSFLSQEYSGSVANEANVYLNSKGTRS
                     SVRLQGASNFAGIWNFEVGENFAGEATLRRIYGTWEHNMINHLQVFSYFDTKGKQTCR
                     ATLELSPWTMSTLLQVHVSQPSPLFDLHHFDQEVILKASTKNQKVSWKSEVQVESQVL
                     QHNAHFSNDQEEVRLDIAGSLEGQLWDLENFFLPAFGKSLRELLQIDGKRQYLQASTS
                     LHYTKNPNGYLLSLPVQELTDRFIIPGLKLNDFSGIKIYKKLSTSPFALNLTMLPKVK
                     FPGVDLLTQYSKPEGSSVPTFETTIPEIQLTVSQFTLPKSFPVGNTVFDLNKLTNLIA
                     DVDLPSITLPEQTIEIPSLEFSVPAGIFIPFFGELTAHVGMASPLYNVTWSTGWKNKA
                     DHVETFLDSTCSSTLQFLEYALKVVGTHRIENDKFIYKIKGTLQHCDFNVKYNEDGIF
                     EGLWDLEGEAHLDITSPALTDFHLHYKEDKTSVSASAASPAIGTVSLDASTDDQSVRL
                     NVYFRPQSPPDNKLSIFKMEWRDKESDGETYIKINWEEEAAFRLLDSLKSNVPKASEA
                     VYDYVKKYHLGHASSELRKSLQNDAEHAIRMVDEMNVNAQRVTRDTYQSLYKKMLAQE
                     SQSIPEKLKKMVLGSLVRITQKYHMAVTWLMDSVIHFLKFNRVQFPGNAGTYTVDELY
                     TIAMRETKKLLSQLFNGLGHLFSYVQDQVEKSRVINDITFKCPFSPTPCKLKDVLLIF
                     REDLNILSNLGQQDINFTTILSDFQSFLERLLDIIEEKIECLKNNESTCVPDHINMFF
                     KTHIPFAFKSLRENIYSVFSEFNDFVQSILQEGSYKLQQVHQYMKAFREEYFDPSVVG
                     WTVKYYEIEEKMVDLIKTLLAPLRDFYSEYSVTAADFASKMSTQVEQFVSRDIREYLS
                     MLADINGKGREKVAELSIVVKERIKSWSTAVAEITSDYLRQLHSKLQDFSDQLSGYYE
                     KFVAESTRLIDLSIQNYHMFLRYIAELLKKLQVATANNVSPYLRFAQGELIITF"
     exon            203..241
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            242..357
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            358..503
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            504..657
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            658..813
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            814..938
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1024
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1244
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1472
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..1593
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            1594..1740
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            1741..1952
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            1953..2190
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            2191..2367
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            2368..2559
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            2560..2727
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            2728..2939
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            2940..3122
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            3123..3244
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            3245..3455
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            3456..3631
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            3632..3819
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            3820..3965
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            3966..4339
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            4340..11806
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            11807..11921
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            11922..12105
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     exon            12106..14076
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
                     /inference="alignment:Splign:2.1.0"
     regulatory      13906..13911
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
     polyA_site      13941
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
     regulatory      14054..14059
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
     polyA_site      14076
                     /gene="Apob"
                     /gene_synonym="Aa1064; Ac1-060; Apo B-100; ApoB-100;
                     ApoB-48"
ORIGIN      
        1 gctgtagatc aagtccctcc ctgagtgcag cctcggacga tccggcagag ccagcagcgg
       61 ggctaggccc gtgccgtggc caggccacag ccaagaagcc accctaccca tccatcggcc
      121 atgggcccac agaggcctgc cctgcgggca ccgctactgc tgctgttcct gcttctgttc
      181 ttggacacca gcgtctgggc tcaagatgaa gtcctagaaa acttcatctt gaactgtcca
      241 aaagatgcaa ctcgattcaa gcacctccgg aagtacgtgt acagctatga ggctgaaagt
      301 tccagcggtg tccggggcac tgctgactcc agaagcgcca ccaagattaa ctgcaaggtg
      361 gagctggagg tcccccaagt ctgcactctc atcatgagga ccagccagtg tacccttaaa
      421 gaggtgtatg gcttcaaccc tgagggcaaa gccttgatga agaaaaccaa gaactctgaa
      481 gagtttgcat ctgccatgtc caggtacgag ctcaagctgg cctttcctga agggaaacga
      541 gttgctcttt accctgacct gggtgaacct aactatatcc tgaacatcaa gaggggcatc
      601 atctctgctc ttctggttcc cccagagaca gaagaggaca aacaagtttt gttccaggat
      661 acagtctatg gaaactgctc aactcaggtt acagtgaatt caagaaaggg gaccgtggcg
      721 acagaaatgt ccacagagag aaacctgcag cattgtgatg gcttccagcc catcagcaca
      781 agtgtcagcc ctctggctct catcaaaggc ctggtccgcc ccttgtcaac tctaatcagc
      841 agcagccaat cttgccagta cactctggag cccaagagga agcatgtgtc tgaagccatc
      901 tgtaatgaac agcatctttt cctgcctttc tcctacaaga ataagtatgg aatcatgacc
      961 catgttacac agaaactgag tcttgaagat acacctaaga tcaacagtcg cttcttcaga
     1021 ggaggtatca accaagtggg tctggctttc gagagcacca agtccacatc acccccaaag
     1081 caggctgatg ctgttttgaa gacccttcaa gaactgaaaa aattgtccat ctcagagcag
     1141 aatgctcaga gagcaaatct cttccataaa ctggttactg agctgagagg tctcagtggt
     1201 gaagcgatca catccctctt gccacagctg atcgaagtgt ccagccccat cactttacaa
     1261 gccttgattc agtgtggaca gccggagtgc tatactcaca tcctccagtg gctgaaaact
     1321 gagaaggctc accccctcct gattgacatt gttacctacc tgatggctct gatcccaaat
     1381 ccctcagtgc agaggctgca ggagatcttt aatactgcca aggaactgca gagccgagcc
     1441 accctgtatg cactgagcca tgcggttaac agctattatg ctattatgga ccattcaagg
     1501 agcccagttc tggaagatat tgctggttac ctgatgaagc agattgataa tgaatgcatg
     1561 ggggatgaag accgcacctt cttgattctg agggtcattg gtaatatggg cagaaccatg
     1621 gaacgagtga tgccagcact caagtcctca gtcctcaact gtgtgagaag cacaaaacca
     1681 tctctgcaga ttcagaaagc tgctctccag gccctgagga agatggagat gggagatgag
     1741 gtccgaacga tcctttttga tacgtttgtg aatgatgttg ccccagtgga gaagagactg
     1801 gctgcctatc tcttgttgat gaggagccct tcctcatcag atattaacaa aattgccaag
     1861 cttctccaat gggaacagag tgaacaggtg aagaacttcg tggcttctca cattgccaac
     1921 atcttgaact cagaagaact ttatgtccaa gatctgaaaa atctgatcaa aaatgctctg
     1981 gtgaattctc gacttccaac gatcatggac ttcagaaaat tttcccgaaa ctatcaaatt
     2041 tccaaatctg tttctattcc actgtttgac ccagtctcag ccaaaatcga agggaatctt
     2101 gtatttgatc caagcagtta tcttcccaaa gaaagcatgc tgaaaacaac cctcacggtc
     2161 tttggaattg cttcacttga tctctttgag attggtttag aaggaaaggg ctttgagcca
     2221 acactggaag ctctttttgg taagcaagga ttcttcccag acagtgtcaa caaggctttg
     2281 tattgggtca atggtcaagt tccagatcgt gtctccaagg tcttggtaga ccactttggc
     2341 tacactaagg atgacaaaca tgaacaggac atggtgaatg gaatcatgcc cattgtggac
     2401 aagttgatca aagaactgaa atctaaagaa attcctgaag ccagggccta tctccgcatc
     2461 ctaggaaaag agcttggctt tgtcaggctc caagacctcc aagtcctggg aaagttactg
     2521 ctgaatggtg cgcaaacttt tcggggagtg ccccagatga ttgtacaggc catcagagaa
     2581 ggatcaaagg atgacttgtt tctccactac atcttcatgg agaatgcctt tgagctcccc
     2641 actggagtag ggctacagct gcaagtgtcc tcatctggag tcttcacccc tgggatcaag
     2701 gctggtgtga gactggagtt agccaatatt caggcagagc tagtggcaaa gccctctgtg
     2761 tctttggagt ttgtgacaaa tatgggcatc atcatcccag acttcgctaa gagcggtgtt
     2821 cagatgaata caaacttctt ccacgagtca ggcctggagg ctcgagtggc cctgaaggct
     2881 gggcagctga aggtcatcat tccttctccg aagaggccgg tcaagctgtt cagtggcagc
     2941 aacacgctgc acctggtctc taccaccaaa acggaagtga tcccaccttt gattgagaac
     3001 aggaagtcct ggtcaacttg caagcctttc ttcaccggca tgaactactg taccacaggg
     3061 gcttactcca atgccagctc cacagagtct gcctcttact acccactgac aggagacaca
     3121 aggtatgagc tggagttgaa gcccacagga gaggtggagc agtattccgc cagtgcaacc
     3181 tatgagctcc taaaagagga caagtctttg gttgacacac tgaagttcct agtgcaagca
     3241 gaaggagtcc agcagtctga agctactgca atgttcaaat ataatcggcg aagcaggacc
     3301 ttatctagtg aagtcctaat accagggttt gatgtcaact ttggaacaat cctcagagtt
     3361 aatgatgaat cttctaagga caaaaacact tacaaactca tcctggacat tcagaacaag
     3421 aaaatcactg aggtttctgt cgtgggccac gtgagttatg acaaaaaggg agatggcaag
     3481 gtcaaaggtg ttgtttccat accacgtttg caagcagaag ccaggagtga ggttcatacc
     3541 cactggtccc ccaccaaact gctcttccaa atggactcat ctgctacagc ttacggctca
     3601 acaatttcca agagagttgc atggcgttat gataatgaga aaatcgaatt tgattggaac
     3661 acgggcacca atgtggatac caaaaaggtg gcctccaatt tccctgtgga tctttcccgt
     3721 tatcctagaa tggtgcatga gtatgccaat ggtctcctgg atcacagagt ccctcagaca
     3781 gatatgactt tccgacacat gggttccaaa ctaattgttg caacaaacac atggcttcag
     3841 atggcaacca ggggtcttcc ttacccccaa tctctacagg atcacctcaa tggcctctca
     3901 gagttgaacc tcccaaaagt gggattgcca gacttccata tcccagacaa cctcttccta
     3961 aaaactgatg gccgagtcaa atacacacta aacaagaaca gaatagagat tgacattcct
     4021 ttgcctttgg gtggcaagtc ttcaaaagac ctcaaggtgc cagaaagtgt gaggacacca
     4081 gccctcaact tcaagtctgt ggggttccat ctgccgtctc aagaggtcca gattcccact
     4141 tttacaatcc ccaagacaca tcagctgcaa gtgcctctct tgggcattct ggacctttcc
     4201 acaaatgtct acagcaactt gtacaactgg tcagtctcct acactggtgg caacaccagc
     4261 agggatcact tcagccttca ggctcagtac cgcatgaagg ctgactctgt ggttgacctg
     4321 ttttcctaca gtgtgcaagg atctggagaa acaacatacg acagcaagag cacattcact
     4381 ttatcgtgtg atgggtctct acatcataaa tttctagatt ccaaattcaa agtcagccac
     4441 gtagaaaaat ttggaaacaa cccagtctcg aaaggtttat taacatttga aacatctagt
     4501 gccttgggac cacagatgtc tgctacagtt cagctggact caaaaaagaa acaacatctg
     4561 tatgtcaaag acatcaaggt tgacggacag ttcagagtat tttcattgta cgctcaaggt
     4621 gaatatggcc tgtcttatga gagagattct atgactggcc agatgagcgg agaatccaac
     4681 atgaaattta actccaccta cttccagggc accaaccaga tagtgggaat gtaccaggat
     4741 ggaatgctgt ctgtcacttc cacctctgac ctgcaagatg gcatattcaa gaacacagct
     4801 tccctaaaat atgaaaacta tgagttgact ctgaaatccg acagcagtgg gcagtatgag
     4861 aactttgctg cttccaacaa gctggacatg accttctcta agcaaagcgc actgctgcgt
     4921 tctgaacacc aggccaacta caagtccctg agacttgtca cccttctttc tggatccctc
     4981 acttcccagg gtgtagaatt aaatgctgac atcttgggca ccgacaaaat taatactggt
     5041 gctcacaagt caacgctaaa gattgcacaa gatggagtat ctaccagtgc aaccaccaac
     5101 ttaaagtaca gcccgctgct gctggagaat gagttgaacg cagagcttgg gctctctggg
     5161 gcatccatga aattgtcaac aagtggccgc ttcaaagaac accatgcaaa attcagtctt
     5221 gatgggagag ctgccctcac agaggtatca ctgggaagca tttaccaggc catgattctg
     5281 ggtgcagaca gcaaaaatgt cttcaacttc aaactcagcc gagaaggact gaagctatcc
     5341 aatgacatga tgggctccta cgctgaaatg aaactcgacc acacacacag tctgagaatt
     5401 tcaggtctct ccctggactt cttctcaaaa atggacaata tttacagtgg agacaagttt
     5461 tataagcaga attttaactt acagctacag ccctattctt ttggaattac tttaagcaat
     5521 gatctgaaat atgatgctct agttttgacc aacaatggaa ggttacggct ggaaccactg
     5581 aagctgaatg tgggtggcaa ctttaaggga acctaccaaa ataatgagct gaaacacatc
     5641 tataccatct cttatactga cctggtagta gcaagttaca gagcagacac tgtagctacg
     5701 gttcagggtg tggagttcag ccataggcta aatgcagaca tcgaagggct ggcttcctcc
     5761 gttgatgtca ctaccagcta cagttcagat ccactgcatt ttaacaatgt tttccgcttt
     5821 gttctggcac cgtttacctt gggcgtcgac acacatacaa gtggtgatgg gaaaatgtcc
     5881 ctctggggag aacacactgg gcagatgtac agtaaatttc tgttgaaagc agaacctctg
     5941 gcacttacct tctctcatga ctacaaagga tccacgagcc acaatctcct gtacaagaac
     6001 agcgtcagta cagctcttga gcacacactc agtgccttgc tgactccagc tgaacagaca
     6061 agcagctgga aattcaagac cagcctgaat gacaaagtat acagccagga atttgaagcc
     6121 tacaacacta aagacaaaat tggtatcgag cttagtggac gggctgacct ctctgggctg
     6181 tactctccaa ttaaagtgcc gtttttctac agtgagcctg tcaatgttct taatagcttg
     6241 gagataaatg atgcctttga cgagccccga gaattcacaa ttgatgctgt ggtgaaatac
     6301 gataagaacc aagatgtcca cactatcagc ctcccattct tccaaagcct gccagattat
     6361 ttggagagaa atcgaagagg aattataagt ctactggaag ccatgaaggg ggaattacaa
     6421 cgcctcagtg ttgatcagtt tgtgaggaaa tatagagtgg ccctgagcag gcttcctcag
     6481 cagattcatg attatctgaa tgcatctgac tgggagagac aagtagctgg tgccaaggaa
     6541 aaattaactt ctttcatgga aaactataga attacagata atgatgtact aattgcctta
     6601 gatagtgcca aaatcaactt gaatgaaaaa ctctctcaac ttgagacata cgcgatacaa
     6661 tttgatcagt atattagaga taattatgat gcacaggact taaaaagaac tattgctcag
     6721 attattgata gaatcattga aaagctaaaa atgcttgacg aacagtatca tatccgtgta
     6781 aatctagcaa aatcaatcca taatctctat ttatttgttg aaaatgttga tcttaaccaa
     6841 atcagtagta gtggtgcgtc ttggatccaa aatgtggata ccaaatatca aatcagaatc
     6901 cagatacaag aaaaactcca gcatctcaga acacagattc ataatataga cattcaacag
     6961 cttgctgcag agttaaaaca acagattgaa gctcttgatg tcccaatgca tttagatcaa
     7021 ctgagaactg caattctatt ccaaagaata agtgtcatta ttgagcgtgt caaatacttt
     7081 gttatgaatc ttattgaaga ttttaaagta actgagaaaa tcaatacttt tagagttata
     7141 gtccgtgagt taattgagaa atatgaagta gaccgacaaa tccaggtttt aatggataaa
     7201 tcaatagagt tggcccacag atacagcctg agtgagcctc ttcagaaact aagtaatgtg
     7261 ctacagcaaa ttgagataaa agactactat gataaattgg ttggttttat tgatgacact
     7321 gtcgagtgga ttaaagcagt gtctttcaaa aatatcattg aagaactgaa tagattgatt
     7381 gacatgtcgg tgaaaaagtt gaaagccttt gattatcacc agtttgtaga caaaaccaac
     7441 agcaaaatcc gtgagatgac tcagagaatc aatgctgaaa tccaagctct cgaactccca
     7501 cagaaaactg aagcattaaa actgtgggta gaagacttca aaaccacggt ctccaactcc
     7561 ctggaaaaac tcaaggacac caaagtaact gtggtcgttg attggctgca ggatggtttg
     7621 gctcaaataa aagcccaatt ccaagatgct ttagaagatg tacgagaccg aatttatcaa
     7681 atggacattc agggggaact ggagcgctgc ttgtctctgg taagccaagt ttacagcaca
     7741 gtggtcacct acatttctga ctggtggact ctgactgcta aaaacataac agactttgca
     7801 gagcaatatt ccacccaaaa gtgggctgag agtgtgaaag cactggtgga acaaggattc
     7861 attgttcctg aaatccaaac atttctgggg accatgcctg catttgaggt cagtctccac
     7921 gctctccaag aagctaactt tcagactcct gactttatag tccccttgac agatttgagg
     7981 attccatcaa tttggataaa cttcaaaatg ttaaagaatg taaaaatccc attgagattt
     8041 tccactccag aattcactct cctcaacacc ttccgtgtcc gttcctttac aattgacttg
     8101 ctggaaataa aagcaaagat cattcgaact atcgaccaaa tgctgagcag tgagctacag
     8161 tggcctcttc cagaagtgta tttgagagac ctggagatgg tgaacatttc tcttgcaaga
     8221 ctctctctgc cagacttcca tgtaccagaa atcacaattc cagaattcac aatcccaaat
     8281 gtcaatctca aagatttaca ggttcctgat cttcacatac cagaattcca gcttcctcac
     8341 ctctcatgca caactgaaat acctgctttc ggcaaactac atagcgtcct gaaaatccaa
     8401 tctcccctct ttatattaga tgctagtgcc aacatacaga acataactac ttcagagaac
     8461 aaagcagaga ttgtggcttc tgtcactgcc agaggagagt ccaaatttga agctctcaat
     8521 tttgattttc aagcacaagc tcagttcctg gagttaaatg ctaatcctct ggtactgaag
     8581 gaatccgtga acttctccag taaacatgtg agaatggagc atgagggtaa gatattagtt
     8641 tctggaaaag cccttgaggg aaaatcagac acggttgcaa gattacacac agagaaaaat
     8701 acagtggagt ttaataatgg tattgttgtc aagataaaca atcaattcac ccttgacagt
     8761 caaacaaagt acttccacaa gttgagtgtc cccaggctgg acttctccag taaggcttct
     8821 ctcaacaatg aaatcaagac actattagaa gctggacata tggcatggac ttcttcaggg
     8881 acagggtcat ggaactgggc ctgtcccaac ttctcagatg aaggcataca ttcatccaaa
     8941 attagcttca ttgtggatgg ccccattgct tcttttggat tgtccaataa cataaatggc
     9001 aaacacctaa gggttgtcca aaaactgact tctgaatctg gcttcctcaa ctattctagg
     9061 tttgaagttg agtcaaaagt tgaatctcag cacgtgggct ccagcattct aactgccgag
     9121 ggtcgggcac tgcttgggga tgcaaaggca gaaatgactg gtgagcacaa tgccaactta
     9181 aatggaaaag ttattggaac gttgaaaaat tctcttttct tttcggcaca accatttgag
     9241 attactgcat ccacaaataa tgaagggaat ttgaaagtta gttttccact aaagttgact
     9301 gggaaaatag acttcctaaa taactatgca ctgtttctga gcccccatgc ccaacaagca
     9361 agctggcaat tgagtactag attcaatcag tacaaataca atcaaaattt ttcggctata
     9421 aacaatgagc acaacatgga agccagtata gtaatgaatg gagatgccaa ccttgatttc
     9481 ttaaacatac ctttaacaat tcctgaaatt aatctacctt acacaaggtt cacaactccc
     9541 ttactgaagg atttctccat atgggaagaa acgggcttga aagaattttt gaagacaaca
     9601 aagcagtcat ttgacttgag tataaaggct caatataaaa agaacagaga caagcattct
     9661 gttgttatcc ctctgaaaat gttttatgag tttatgctca acaatgtcaa ttcttgggac
     9721 agaaaatttg agaaagtcag agacaatgca ttacattttc ttaccgcatc ctataatgaa
     9781 acaaaaatta agtttgataa gtacaaaact gaaaattccc tcaatcagcc ttccaggacc
     9841 tttcaaaatc gtggacacac tatcccagtt ctcaacattg aagtgtctcc atttgctgta
     9901 gagacactgg cttccagcca tgtgatcccg aaagcaatcc gcaccccaag cgtcacaatt
     9961 ccaggtccta acatcattgt gccttcatac aggttagtgc tgccgtctct acagttgcca
    10021 gttttccata tccctaggac tctattcaag ttttccctcc cagatttcaa gaaattaagc
    10081 actattgaca atatttatat tccagccatg ggcaatttca cctatgactt ttcttttaaa
    10141 tcaagtgtca tcacactgaa taccaatgct ggactttata accaatcaga tctcgttgct
    10201 cgttttcttt cttcctcttc atttgtcacg gatgccctgc agtacaaact agagggtaca
    10261 tcacgtctga tgcggaaaaa agtattgaag ttagccaccg ctgtctctct aactaacaaa
    10321 tttttaaagg gaagtcatga cagcaccatt agcttaacca agaaaaacat ggaagcttca
    10381 gtgaaaacaa ctgccaacct ccacgctccc attttcacaa tgaacttcaa gcaggaactt
    10441 aacggaaaca ccaagtcaaa gcccactgtc tcatcctcca ttgaactaaa ctatgacttc
    10501 aattcctcaa agctgcactc tgcagcaaaa ggaggtgttg atcacaagtt cagcttagaa
    10561 agtctcactt cctacctttc cattgagtca ttcaccaaag gaaatatcaa gggttcgttc
    10621 ctttcacagg aatattcagg aagtgtcgcc aatgaggcga atgtgtacct gaattctaag
    10681 ggtactcggt cttcagtaag gttacaagga gcctctaatt ttgctgggat ctggaacttt
    10741 gaagtaggag aaaattttgc tggagaagct actctccgac gcatctatgg cacatgggaa
    10801 cacaatatga taaaccattt acaggtattc agctactttg acacaaaagg aaaacaaaca
    10861 tgcagagcca ccctagagct ctccccatgg accatgtcaa cccttctaca ggttcatgtg
    10921 agtcaaccca gtcccctctt tgatctccat cactttgacc aggaagtgat cctgaaagct
    10981 agcactaaga accagaaggt cagctggaaa agtgaggtcc aggttgaatc acaggttctt
    11041 cagcacaatg cacacttctc caatgaccaa gaagaagtac gccttgacat tgctggatcc
    11101 ttagaaggac agctgtggga ccttgaaaat ttctttctac cggcatttgg caagagcttg
    11161 agggaactcc tacagataga cggaaagcgt cagtatcttc aagcttcgac ttctcttcac
    11221 tataccaaaa acccgaatgg ctatctcctc tcactccctg tgcaagaact gactgataga
    11281 ttcattatac cagggctgaa actaaatgac ttcagtggaa tcaaaatcta taagaaatta
    11341 agtacttcac catttgccct caacctaaca atgctcccca aagtaaaatt ccctggggtt
    11401 gatctgttaa cacaatactc taaaccagag ggctcctctg tccctacctt tgagacaact
    11461 atacctgaaa ttcaattaac tgtgtcccag tttacacttc caaagagctt tcccgttggc
    11521 aacactgtct ttgatctgaa taagctaacc aacctaattg cagatgttga tctgcctagt
    11581 atcaccctgc cagagcagac cattgagatc ccatcccttg agttctctgt acctgctggg
    11641 atttttattc cgttctttgg agaactgact gcacacgttg ggatggcctc tcccctgtat
    11701 aatgtcacgt ggagcactgg ttggaaaaac aaagcagacc atgttgaaac attcctggat
    11761 tccacatgca gttcaacctt gcagtttctg gagtatgctc taaaagttgt gggaacacac
    11821 aggattgaaa atgataagtt catctataaa atcaaaggaa cacttcaaca ctgtgacttc
    11881 aatgtgaagt ataacgaaga tggtatattt gaaggacttt gggacttgga gggagaggct
    11941 catctggaca tcaccagccc agcactgact gacttccatc tgcactacaa agaagacaag
    12001 acaagtgtgt ctgcctcagc agcctcccca gccataggca ctgtgagtct ggatgcaagc
    12061 acagatgacc agagtgtgag gctgaatgtc tacttccgcc ctcagtcccc tccagataat
    12121 aaactcagca tattcaaaat ggagtggagg gacaaggagt ctgatggtga aacatacatc
    12181 aaaattaact gggaagaaga agcagctttc agattgctag actccctaaa aagcaatgtg
    12241 cccaaggctt ctgaggctgt ttatgattat gtcaagaagt accacctggg acatgcttct
    12301 tcagagctaa gaaaaagtct tcagaatgat gctgaacacg ccataaggat ggttgatgag
    12361 atgaacgtga atgcccagag ggtaacccgt gatacctacc agagtctata taagaagatg
    12421 ttggctcagg agagccagag tatccctgag aaactcaaga aaatggtgtt aggcagtcta
    12481 gtacgtatta ctcagaagta ccacatggca gtcacatggc tgatggactc agtcattcat
    12541 ttcctgaagt tcaatagagt ccagttccca gggaatgctg gaacatatac tgtggacgaa
    12601 ctttacacta tagccatgag ggaaaccaag aagttactct ctcagctgtt taatgggtta
    12661 ggacacctgt tttcctatgt tcaagaccaa gtagagaaat caagagtaat caatgacata
    12721 acatttaaat gtcccttttc cccaacacct tgtaaactaa aagatgtcct attgattttc
    12781 agggaggact taaacatttt atccaactta ggccaacagg atatcaattt tacaacaata
    12841 ctaagtgact ttcagagctt tttggagaga cttttagaca tcatagaaga aaaaattgaa
    12901 tgcctaaaga acaatgaatc tacttgtgtc cctgatcata tcaacatgtt cttcaaaaca
    12961 catatcccat ttgcatttaa atccctgaga gaaaacatat actctgtctt cagtgagttc
    13021 aatgactttg ttcaatccat acttcaagag gggtcctata agctacagca ggtccatcag
    13081 tatatgaagg cctttcgtga agagtatttt gatccgagtg tggttggctg gacagtaaaa
    13141 tattatgaaa tagaagaaaa gatggttgac cttatcaaga cccttttggc tcctctgagg
    13201 gatttctact ctgaatacag tgtgacagct gctgattttg cttccaaaat gtcaactcag
    13261 gttgagcaat ttgtgtccag ggatatcaga gagtatctta gcatgcttgc tgacataaat
    13321 ggaaagggga gggaaaaggt tgcagagctt tctattgtgg taaaggaaag aataaaaagc
    13381 tggtccactg cggtggcaga aataacgtct gattacctcc ggcagctcca ttccaaactg
    13441 caggattttt cagaccagct ctctggctac tatgaaaaat tcgttgctga gtccacaaga
    13501 ctgattgacc tgtccattca aaactaccac atgtttctca gatacatcgc tgagttactg
    13561 aaaaagctgc aggtggccac agccaataat gtgagcccct acctaaggtt tgctcaagga
    13621 gaactgatta tcaccttctg attcgttcat tgatgcattc aaattaaacc tccacatagt
    13681 aggagacttt ttcaactatt ataaaaacca tcctgagcca gacctgcagt caacagcaag
    13741 agcaggaagc gcataggaac tacacctgca accaagctgg cacaaagacc aagaattctg
    13801 aagcagccca aactcaagat gacatatttt tacaagttag agaaaaatca agatctgagt
    13861 tatcttgaca aactcgggat ggaaagtagg agggagggga aagcaaataa atacttcctt
    13921 attgtgtagc atacccctca acttggctca tttgtattgt aacatattag atcgcgagca
    13981 atctggcttt cctaaccctg gttcagaaaa aaaaataggg ataataccta tataggattg
    14041 ttcatgaaaa ttaattaaag taataggtat gggaaaaaaa aaaaaaaaaa a
//
