LOCUS       NM_001409174            5003 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus aph-1 homolog B, gamma secretase subunit like 2
            (Aph1bl2), mRNA.
ACCESSION   NM_001409174 XM_003750532
VERSION     NM_001409174.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5003)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Jul 12, 2022 this sequence version replaced XM_003750532.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.2165473.1,
                                           SRR26360176.1299857.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760389,
                                           SAMEA5760475 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-177               JAXUCZ010000008.1  76258724-76258900   c
            178-348             JAXUCZ010000008.1  76257329-76257499   c
            349-419             JAXUCZ010000008.1  76251178-76251248   c
            420-542             JAXUCZ010000008.1  76250277-76250399   c
            543-670             JAXUCZ010000008.1  76243959-76244086   c
            671-5003            JAXUCZ010000008.1  76236827-76241159   c
FEATURES             Location/Qualifiers
     source          1..5003
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..5003
                     /gene="Aph1bl2"
                     /gene_synonym="RGD1559979"
                     /note="aph-1 homolog B, gamma secretase subunit like 2"
                     /db_xref="GeneID:691658"
                     /db_xref="RGD:1597236"
     exon            1..177
                     /gene="Aph1bl2"
                     /gene_synonym="RGD1559979"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..838
                     /gene="Aph1bl2"
                     /gene_synonym="RGD1559979"
                     /note="gamma-secretase subunit APH-1B"
                     /codon_start=1
                     /product="similar to anterior pharynx defective 1b
                     homolog"
                     /protein_id="NP_001396103.1"
                     /db_xref="GeneID:691658"
                     /db_xref="RGD:1597236"
                     /translation="MTAAVFFGCAFIAFGPALSLYVFTIATDPLRVIFLIAGAFFWLV
                     SLLLSSVFWFLVRVITDNRDGPVQNYLLIFGVLLSVCIQELFRLAYYRLLKKANEGLK
                     SINPEETAPSMRLLAYVSGLGFGIMSGVFSFVNTLSNALGPGTVGIHGDSPQFFLNSA
                     FMTLVIIMLHVFWGIVFFDGCEKNKWYILLTVLLTHLLVSTQTLLSPHYEVNLVTAYI
                     IMVLMGIWAFCVAGGSRRSLKLCLLCQDKDFLLYNQRSR"
     exon            178..348
                     /gene="Aph1bl2"
                     /gene_synonym="RGD1559979"
                     /inference="alignment:Splign:2.1.0"
     exon            349..419
                     /gene="Aph1bl2"
                     /gene_synonym="RGD1559979"
                     /inference="alignment:Splign:2.1.0"
     exon            420..542
                     /gene="Aph1bl2"
                     /gene_synonym="RGD1559979"
                     /inference="alignment:Splign:2.1.0"
     exon            543..670
                     /gene="Aph1bl2"
                     /gene_synonym="RGD1559979"
                     /inference="alignment:Splign:2.1.0"
     exon            671..5003
                     /gene="Aph1bl2"
                     /gene_synonym="RGD1559979"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tacccgggca cccgctgccc actgggcact gcagggccct cggggactgg cttccgcggg
       61 cgtcatgacg gctgcggtgt tctttggttg cgccttcatc gccttcgggc ccgcgctctc
      121 cctttacgtc ttcaccatcg ccactgatcc tttgcgagtc atcttcctca tcgccggtgc
      181 cttcttctgg ttggtgtctc tgctgctttc gtctgttttc tggttcctag tgagagtcat
      241 cactgacaac agagatggac cagtacagaa ttacctgctc atctttggag tgttgctctc
      301 tgtctgtatc caagagctgt tcaggcttgc atattatagg ctgttaaaaa aagccaatga
      361 gggtttgaaa agcataaacc ctgaggagac agcaccctcg atgcgactgt tggcctatgt
      421 ttctggcttg ggctttggaa tcatgagtgg agtgttttcc tttgtgaaca ccctgtctaa
      481 tgccttgggg ccaggcacag tgggcattca tggtgattct cctcagttct tccttaattc
      541 agctttcatg acgctggtta tcataatgct gcacgtgttc tggggcatcg tgttttttga
      601 cggctgtgag aagaataagt ggtacatcct cctcacagtt ctcctgaccc acctgctggt
      661 gtccacccag actttactaa gtcctcacta tgaagtgaat ctggtgacag catatataat
      721 catggtgctc atgggcatct gggcattctg tgttgctgga ggcagccgcc gaagcctgaa
      781 actctgtctg ctctgccaag acaaggactt tcttctttac aaccagcgct ccagataacc
      841 tctgacggtc agcacctcca aacagcagcc tgtgtgccag aggaagggca gctggcctct
      901 gttctaaaat gacccttttc ttctggagct ttggagcagc agagcttcta gcctgcaact
      961 gtcctgtgct ttcatgcagc agcctctgga agagctgcag tgtggcctgc agcctggctg
     1021 cacatttgag gcatctgggg aaacaaagcc tgatgcttct gggcctcccc tccagactcg
     1081 agtatcccag atgtgcaata cagctgagtc actggggtcc aatgggaagt ttcagagaac
     1141 ccaaaggcag ttctgtattt gtctcctaag ccaacctctg ctgagcaagt aaatttctga
     1201 aaacctgggt agcccttgtc ttcttatgca ctgacgtcac agactaaagg gctgttctgt
     1261 ctgtggatgg gtttgctgtc cttcaccagc atcataggct gtgcctttaa atgcagtaac
     1321 ctacaccgac attataactt agccacggta aggtccatag ataacctgta gttttcttgc
     1381 tactttttcc attttaaatt tttcttcctc aggtactaaa ttatttattt gagtgtaaat
     1441 ccaggctctg aggattggtt atatgctgat ttccttggaa gaaattggca gtgcaatttc
     1501 tatgcattct aaaagtttat tcattatata atactaatag caacatagcc tcctcagttt
     1561 aagctgctgt gtgtgctgtc tgaagctggc ctcgtcaagg taaagctcac cattttttat
     1621 ctctgagaag ctgggtaggg agatgaacca tatacctctg gaagatcttc tctggacttt
     1681 gtgagaatgt agctcaacca caaagtagtg tgacaatgac acttctcatt tcctcctgtg
     1741 acaccaaaca gtgccattgc cctaatggta cgtggtaaaa ttggcgatcg tcattaagct
     1801 gtcagatttc aagctggcgt gtaacttttc atcttcaggg tttgtctggg ttctcctttc
     1861 agcgacacaa acagcattct ctttatagga ctgtcagagg gctttgttag tcttccagag
     1921 cagtcctctg gcttcctctg taagaggaaa tgctactgaa ttgtgagcct actgtggaaa
     1981 ctgttcccag tccaagtgtt ctaggaactt agagtgtgaa gtagaaattt acctctacat
     2041 ggaagtgatg ccttggtgaa cccagcacac atatgcactt ccgtaagaac caggggcagc
     2101 agagagaggg cttgacagtg acactgaaga tgagcgtgac agcaccatgg tgacaagaag
     2161 atggatgtgt ttgaaatgag gatgcagcca atgttttgag ctgactagaa tttttttttt
     2221 ttttcggagc tggggaccaa acccagggcc ttgcgcttcc taggcaagcg ctctaccgct
     2281 gagctaaatc cccaaccccc gagctgacta gaatcttaac caggaactaa accttaatta
     2341 tgaactccca ccatgcttaa aatatgtgag tgtctcagtg tagagttgca agagtaagaa
     2401 gcttctagca agactacaga cttcccgaga agccaccgtg gttacctcct taaaggctac
     2461 ttcagctcta agtcatggca gtgcctttgc tggagttcgt agatttgtag ttttatataa
     2521 gagtttcctt ggagtagaaa gacaaagaca tagaaagaaa aacagcaaac ttcactttac
     2581 agagccaaaa acaagtagat gcccacagag ctgggatgtg tttcttcctg aacatggtat
     2641 tttctcttgt taaactaagg aagaaacaca tatcattggt tattactgct gtcttataca
     2701 ccttgtatgt agatattttg ataaaatgtt tgcttgtctg aggtatggag aacctgagaa
     2761 tttgactgtt gttaaacttg agctctaagc aaataatcta agcaaaccat gatattacaa
     2821 atgagacaat tataaaatct caattaataa aagctcagat gaatggctgg gaagatggtt
     2881 cactggttta gcacacatac tgttctttca gagaactcaa gttcagatcc cagaacctcc
     2941 tttgagcagc tcaccaccac ttctaagtac agctccagga gctccaaggc atctggctct
     3001 caactgcaac tgtattcacg tgcctacaca gaccagagca tgcatactca acaacaatag
     3061 aaccatcaca cattggaagg gaatttgcct agagaaactt agttgaggaa attattgagt
     3121 agtccttggt tgcctatagt agttctgata ctgtgagtgt cgttgtagct caggcagaac
     3181 tctctcaata gcctgctttg caccttacct aggaagcctg agggaggagg agtcctacac
     3241 atacacactg aaatgctgct cttattaata attgaaaagg agtagcctgg atgttgtatg
     3301 ctgtgcttcg cacaggtttt ctgtgaagag agaaaagtgc acataaaatt gacctggaat
     3361 cttgaacatt gttttagcgc ttgtgtaaca gatattcgtt ggccatgtga atatcaggga
     3421 cagattcagt tgcgctctta tataagccac gtttatcttt agtttgtttg aaccagtgct
     3481 cattactgga gctgcgtaaa gccacccgtc tgttcttttg cttgcctaac tagcagtgta
     3541 gtaacagtga cctcttcaga tgaaatgtgc tcaaaggagg tgaggacagt gtcttcagac
     3601 tgcacagaag atgccttttg ttcccagtaa atgtaagtac tgtgagagag gctttctata
     3661 cctagttctt gttacattag cttcagccct gtatcaacac aggtgtaaac aatagatgtg
     3721 agcactaaac ccttgctggc gattgtaggc atgtgccacc atgcctagct aaaggatatc
     3781 attacgatta caatgtttat tttcttagtt taacagtagg ctttacttta gtctttttta
     3841 atgtttagag gaaatgagca cgatctctgt gtatcatcta taacgttttt atatgttaaa
     3901 cctttatgac cttcactctg tagcagcaga ccttccagac ctgtgttttt tccaatgggc
     3961 agtaaaaaca ttatttaaca tttcattctt aatatctcac tcatttggag tagaccatcc
     4021 ttcagtatct gttactatag ttactgcctt gcttgaaact tggctgtaca ttctgttgtt
     4081 tattactgat tagttatgag acttccaaag tgaagttcat tagctaattt acaatccatg
     4141 aggcatgtct catatctctg tattcagaat caatttggca caaagatgtt cttgaggctt
     4201 cttaaagcca agtaaagggg aaaaaaccct taaggatttt ggagttttac tttgaaaact
     4261 ctctaaaaaa ttgtgaaaga gtgaacttac aaatccttac agagtagtag ctgaagacag
     4321 aggcaggcaa aaacagcatg atttagcttc tacttggcag cttcaaatag cttagtcttg
     4381 tcactttcct cccctagtga ggagatgagg cagctaaggg gtcatgtatg ccctttgccc
     4441 tcagacagga gggtcagaaa actgggagga cctgtcattg gaatccatat ggtgagagtt
     4501 ggcccttctg aagtggggcc gttccaggtt tctactgatc atcttcctgg atgacccagc
     4561 ctctggacca atagctctga gctacagtac agtatacttt caatacagct gaggaggtgc
     4621 acactcctca tgtgtcagcc cagcgtcggc taccgcttca ctggcccttt ctcaataaag
     4681 tcgtgagtct tgctaggtgt cacttacttg gggtttagtt agaatggagg tttcctgatg
     4741 aacagcctca gatgtgagaa tcttctacta gaaaaatata aatattttgt cttcatctta
     4801 tcaaaaatta gaatagaaga actgttcagc tgacttattg atctagattt gagtagaaca
     4861 cttgtattcc attcaacaca cattttaaca tgtccaatac tttaaggctc agtgacttgt
     4921 atatgatatt tgttatttaa gtataaatca tgtaaaacta tactttaaaa aagtatttgt
     4981 gtaaaataaa aggtggaatg tca
//
