LOCUS       NM_001037220            3691 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus adaptor related protein complex 5 subunit zeta 1
            (Ap5z1), mRNA.
ACCESSION   NM_001037220 XM_003751130 XM_003752556
VERSION     NM_001037220.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3691)
  AUTHORS   Hirst,J., Barlow,L.D., Francisco,G.C., Sahlender,D.A., Seaman,M.N.,
            Dacks,J.B. and Robinson,M.S.
  TITLE     The fifth adaptor protein complex
  JOURNAL   PLoS Biol 9 (10), e1001170 (2011)
   PUBMED   22022230
  REMARK    Erratum:[PLoS Biol. 2012 Mar;10(3). doi:
            10.1371/annotation/89dff893-c156-44bb-a731-bfcc91843583]
REFERENCE   2  (bases 1 to 3691)
  AUTHORS   Slabicki,M., Theis,M., Krastev,D.B., Samsonov,S., Mundwiller,E.,
            Junqueira,M., Paszkowski-Rogacz,M., Teyra,J., Heninger,A.K.,
            Poser,I., Prieur,F., Truchetto,J., Confavreux,C., Marelli,C.,
            Durr,A., Camdessanche,J.P., Brice,A., Shevchenko,A.,
            Pisabarro,M.T., Stevanin,G. and Buchholz,F.
  TITLE     A genome-scale DNA repair RNAi screen identifies SPG48 as a novel
            gene associated with hereditary spastic paraplegia
  JOURNAL   PLoS Biol 8 (6), e1000408 (2010)
   PUBMED   20613862
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3691)
  AUTHORS   Farkas,R.H., Qian,J., Goldberg,J.L., Quigley,H.A. and Zack,D.J.
  TITLE     Gene expression profiling of purified rat retinal ganglion cells
  JOURNAL   Invest Ophthalmol Vis Sci 45 (8), 2503-2513 (2004)
   PUBMED   15277470
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Mar 3, 2021 this sequence version replaced NM_001037220.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript from the same
            strain was available for the full length of the gene. The extent of
            this transcript is supported by transcript alignments and
            orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643290.40547.1,
                                           SRR26643429.42527.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-93                JAXUCZ010000012.1  17221899-17221991   c
            94-228              JAXUCZ010000012.1  17219542-17219676   c
            229-415             JAXUCZ010000012.1  17219264-17219450   c
            416-560             JAXUCZ010000012.1  17218676-17218820   c
            561-670             JAXUCZ010000012.1  17218354-17218463   c
            671-839             JAXUCZ010000012.1  17217486-17217654   c
            840-980             JAXUCZ010000012.1  17216170-17216310   c
            981-1018            JAXUCZ010000012.1  17215997-17216034   c
            1019-1181           JAXUCZ010000012.1  17215765-17215927   c
            1182-1363           JAXUCZ010000012.1  17214105-17214286   c
            1364-1506           JAXUCZ010000012.1  17212454-17212596   c
            1507-1647           JAXUCZ010000012.1  17212001-17212141   c
            1648-1759           JAXUCZ010000012.1  17211482-17211593   c
            1760-1857           JAXUCZ010000012.1  17210713-17210810   c
            1858-1990           JAXUCZ010000012.1  17209201-17209333   c
            1991-2205           JAXUCZ010000012.1  17208914-17209128   c
            2206-3691           JAXUCZ010000012.1  17207315-17208800   c
FEATURES             Location/Qualifiers
     source          1..3691
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q11"
     gene            1..3691
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /note="adaptor related protein complex 5 subunit zeta 1"
                     /db_xref="GeneID:641386"
                     /db_xref="RGD:1593125"
     exon            1..93
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..2476
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /note="adaptor-related protein complex 5, zeta 1 subunit"
                     /codon_start=1
                     /product="AP-5 complex subunit zeta-1"
                     /protein_id="NP_001032297.5"
                     /db_xref="GeneID:641386"
                     /db_xref="RGD:1593125"
                     /translation="MFSAGAESLLHQAREIQDEELQRFCSRVTKLLQEAPGPATVDAL
                     QRLFLIVSSTKYPRRLEKACVDLLQTTLCLPTSPEQLQVLCAAILREMSPFNDLTLSC
                     DHTQNTRQLSLVASVLLAQGDRNGEIRQVSQRIFKILENRQPEGPSVRPLLPVLSKVI
                     GLAPGILVEDQTNLLSKRLVDWLRYASIQQGLPYSGGFFSTPRTRQPGPITEVDGAVA
                     SDFFTVLSTGQHFTEDQWVNMQAFSMLRKWLLHSGPEDPGSPDADDKSELEGSMLSVL
                     SAASTASRLLPPRERLREVAFEYCQRLLEQSNRRALRKGDSDLQKACLVEAVLVLDVL
                     CRQDPSFLYRTLSCLKPLHRRLGEDPGSERALVPLAQFFLNHGEAAAMDAEAIYAQLL
                     GSLPSERFHSPTLAFEVIHFCTHNLALFDPHFLSLLRLSFPNLFKFLAWNSPPLTAEF
                     VVLLPALVDAGTAVEMLHALLDLPCLTAALDLQLRSTQTPSERPLWDVSLRVPSCLEA
                     FQDPQFQGLFRHLLRTKASGSTERLTPLHQVLKPMASCARVAQCVEAIPVLLQAFFSA
                     VTQTADGPLINQLALLLLERSDSLYPVPQYEARVHRVLSSQLLVLCKLKPSLVVELSR
                     ELLEFVGSVSSIRSRASMFTCVVWAIGEYLSVTCDKRCTAEQINKFFEALEALLFEVT
                     QSRPSADLPCCPPELVTALMTTLTKLASRSQDLIPRVSLFLSKMRTLAQNPATSSMHS
                     EEDTESIRIRATELLTLLKMPSVAQFVFTPTVGVCQPRYHQDTNVALPLALRTVSRLV
                     EKEAGLLPG"
     exon            94..228
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            229..415
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            416..560
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            561..670
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            671..839
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            840..980
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1018
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1181
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..1363
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..1506
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            1507..1647
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            1648..1759
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            1760..1857
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            1858..1990
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            1991..2205
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
     exon            2206..3691
                     /gene="Ap5z1"
                     /gene_synonym="Kiaa0415"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggaagcccg cgacaacatt tcggtcgccg gtgggcttgg ggctgtggcg gcatgttctc
       61 ggcgggcgcg gagagtctgc tgcaccaggc cagggagatc caggatgagg agttgcagcg
      121 cttctgctcc agggtcacta agctgctgca ggaagcccca gggccggcca ctgtggatgc
      181 cttacagaga ctcttcctca tagtctcatc caccaagtat ccccggaggc tggagaaagc
      241 gtgtgtggac ctgttgcaga ccactctctg cttgcccaca agccctgagc agctgcaggt
      301 cctttgtgct gctatcttga gagagatgtc gccttttaat gacctgaccc tgtcctgtga
      361 tcacacccaa aacacccggc agcttagcct tgtggcctct gtgctcttgg cccagggaga
      421 caggaacgga gaaatcagac aagtgagcca acgcatcttc aagatcctgg agaaccggca
      481 gcctgagggg cccagtgtca ggcccctcct ccccgtcctg tccaaggtca ttggccttgc
      541 cccaggcatc ctcgtggaag accagaccaa cctgctcagc aaaaggctgg tagactggct
      601 ccgctacgcc agcatccagc aagggcttcc gtattcaggg ggcttctttt ctacgcccag
      661 gacccggcag ccaggtccca tcaccgaggt ggatggagca gtggcttctg acttcttcac
      721 ggtactctcc acgggccagc acttcacaga ggaccagtgg gtgaacatgc aggccttctc
      781 catgctgagg aaatggttgc tgcacagcgg ccccgaggac cctggcagcc cagatgcaga
      841 tgacaagtca gagctggagg gctctatgct gtctgtgctc tccgcggcct ccactgcgag
      901 ccgactgctg ccccctcggg agcggctgag ggaggtggcc tttgaatact gccagcgcct
      961 gttggagcag agtaaccgga gagcgctgag gaagggggac tcggacctac agaaagcctg
     1021 cctggtggaa gctgtgttgg tgctagatgt gctgtgccgg caggacccct ccttccttta
     1081 tcgtaccctc tcctgcctga agccactgca caggaggctg ggcgaagacc ctggcagcga
     1141 gcgggctctg gtgcctcttg cccagttctt cttgaaccac ggggaggcgg ccgccatgga
     1201 tgcagaagcc atctacgcgc agctgctagg cagtctccct tctgagcgct tccacagccc
     1261 gactctggcc ttcgaggtca tacacttctg cacgcacaac ctggctctgt tcgaccccca
     1321 ctttctcagc cttctccggc tgagcttccc aaatctattc aagttcctgg cttggaacag
     1381 ccctccgctc acagccgagt ttgtggtact cctccctgct ctcgtggatg ctggaactgc
     1441 tgtggagatg ttgcatgccc tgcttgacct gccctgtctg actgctgccc tggacctaca
     1501 gctcaggtcc acacagaccc cgtcggaaag gccgctttgg gatgtctccc tcagggtccc
     1561 tagctgcctg gaggccttcc aggacccaca gttccaagga ctcttccggc acctgcttcg
     1621 caccaaggcc agcggctcca ccgagagact gacgccactt catcaggtgc tgaagcccat
     1681 ggccagctgt gcccgggtag cccagtgtgt ggaggcaatt cctgtcttgc tccaggcttt
     1741 cttctcagct gtgacccaga ctgccgacgg gcccctcatc aaccagctgg cactgctgct
     1801 cctggagaga agtgactccc tctacccagt ccctcagtat gaggcccgtg tgcacagggt
     1861 gctgagctcc cagctcctgg tgctgtgtaa gctgaaacca tcactggtgg tggaactgtc
     1921 ccgagagctt ctggagttcg tggggagcgt gagcagcatc cgcagccgag ccagcatgtt
     1981 cacctgtgtg gtgtgggcca ttggtgagta tctgtcggtg acctgcgaca agaggtgcac
     2041 agcagagcag atcaacaagt tctttgaagc cctggaagcc ctgctgtttg aagtcaccca
     2101 gtcccgcccc tcagccgact tgccctgctg tcccccagag ctggtcactg cactcatgac
     2161 cacattgacc aagctagcct cccggagcca agacctgatc ccaagggtgt cactgttcct
     2221 gtcaaaaatg cggaccctgg cccagaaccc agccaccagc tctatgcaca gtgaggagga
     2281 tacagaatcc atccggatcc gggctacaga gctgctaacc ctactgaaga tgcccagtgt
     2341 ggcccagttt gtgttcacac ccaccgtggg cgtgtgccag ccccgctacc accaagacac
     2401 caacgtggcc ctgcctctgg ctctgcgtac ggtcagccga ctggtggaga aggaggctgg
     2461 cctcttgcca ggttgaaggg acagtcacca cctaaacagt ggcttcagct gaagagcctg
     2521 ggcagtcgat gataatagag ctcagctgca ggctcaggta gctcgtgagg agcaggaggg
     2581 aggcggacat ggctgtgagg ttggggtcac cagcccctgg gtatgagtca tccctccttg
     2641 tctctgtggc tggctgtagt cagccttgac agctgataag tgactgagtg ttaacttcct
     2701 aggccgagca caaatggcct ggtctgcttc tgctgttact catttctgaa cttgggggca
     2761 gggagcagtg taggaaaaat aaactgtaaa aaatgatgta tgctgggcaa tgggggcaca
     2821 tgcctttcat cccagtactc aggagaaaca gagacaggca gatctgagtt tgaggccagc
     2881 ctggtttaca gagtgagctc catgacagcc agggttacac agagaatccc tgtctcaaaa
     2941 aattaaaaag aaaaaagaaa aaaaaaagaa agaattactt aatatttatg tgtaggtgtt
     3001 tgcacacacc acagcgcaca cggggaaatc aggagacaac ttcggtgatc agttctctcc
     3061 ttcagccatg tgggtcctgg ctgattgcct gactcagtga caagtgcctt tacttacaga
     3121 gccattttac ctgcccccaa gtaaactttc caatgctgtg tacagcccag acctctgcct
     3181 tcctcaggct gggagatcac cagggagcct gaccatggtc tgctgccctt cccacactgc
     3241 cctctgtgga ggggggtccc tgggtctcct gtttgcttcc tgtgttcttg atgtgacaga
     3301 aataacatgc tctggagctg aagctttgcc actaagccct acatttaatc cccagtgtaa
     3361 catggtgatg catactgtaa tcccagaagg tagaggcagg aaggtcagaa gttcaaggtc
     3421 agcctaggct acagaagaaa ttgggctggg aagacttctc agcacataaa agcccttgcc
     3481 ctgatgacac agggttgtcc cctagatcac atgtgtgaag ccacagacca tggtgtgtgt
     3541 gtgcacctgt ggagacagca tcaaagctca aaggcttgct agagcagtgg aaggacgaaa
     3601 tggaaggcaa gaactaactc tcaacgcatg ctgtgccttg gtcacacgag acattttaat
     3661 ctaaataaag ctcaaggtgt attcatgagg g
//
