LOCUS       NM_001398912            1577 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus adaptor related protein complex 5 subunit sigma 1
            (Ap5s1), mRNA.
ACCESSION   NM_001398912 XM_006235038
VERSION     NM_001398912.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1577)
  AUTHORS   Hirst,J., Barlow,L.D., Francisco,G.C., Sahlender,D.A., Seaman,M.N.,
            Dacks,J.B. and Robinson,M.S.
  TITLE     The fifth adaptor protein complex
  JOURNAL   PLoS Biol 9 (10), e1001170 (2011)
   PUBMED   22022230
  REMARK    Erratum:[PLoS Biol. 2012 Mar;10(3). doi:
            10.1371/annotation/89dff893-c156-44bb-a731-bfcc91843583]
REFERENCE   2  (bases 1 to 1577)
  AUTHORS   Slabicki,M., Theis,M., Krastev,D.B., Samsonov,S., Mundwiller,E.,
            Junqueira,M., Paszkowski-Rogacz,M., Teyra,J., Heninger,A.K.,
            Poser,I., Prieur,F., Truchetto,J., Confavreux,C., Marelli,C.,
            Durr,A., Camdessanche,J.P., Brice,A., Shevchenko,A.,
            Pisabarro,M.T., Stevanin,G. and Buchholz,F.
  TITLE     A genome-scale DNA repair RNAi screen identifies SPG48 as a novel
            gene associated with hereditary spastic paraplegia
  JOURNAL   PLoS Biol 8 (6), e1000408 (2010)
   PUBMED   20613862
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Dec 28, 2021 this sequence version replaced XM_006235038.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.2304982.1, DV213958.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-307               JAXUCZ010000003.1  138882634-138882940
            308-518             JAXUCZ010000003.1  138883490-138883700
            519-1577            JAXUCZ010000003.1  138884882-138885940
FEATURES             Location/Qualifiers
     source          1..1577
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36"
     gene            1..1577
                     /gene="Ap5s1"
                     /gene_synonym="RGD1561852"
                     /note="adaptor related protein complex 5 subunit sigma 1"
                     /db_xref="GeneID:499893"
                     /db_xref="RGD:1561852"
     exon            1..307
                     /gene="Ap5s1"
                     /gene_synonym="RGD1561852"
                     /inference="alignment:Splign:2.1.0"
     exon            308..518
                     /gene="Ap5s1"
                     /gene_synonym="RGD1561852"
                     /inference="alignment:Splign:2.1.0"
     CDS             343..945
                     /gene="Ap5s1"
                     /gene_synonym="RGD1561852"
                     /note="adaptor-related protein complex 5, sigma 1 subunit"
                     /codon_start=1
                     /product="AP-5 complex subunit sigma-1"
                     /protein_id="NP_001385841.1"
                     /db_xref="GeneID:499893"
                     /db_xref="RGD:1561852"
                     /translation="MVHAFLIHTLRAPNLEDTGLCRVLYSCVFGAEKSPDDPRPHGAE
                     RDRLFRKEQILAVARQVESLCRLQQQASGCSSTDPQPQFSAESVSLHEAPHGAFHLAA
                     GDPFQEPQTVLWLGVLSLGFTLVLDTHENLLLAERTLRLLARLLLDHLRLLTPGTNFL
                     LRADRIEGILTRFLPHGQLLFLNDQFVQDLEKEFSAAWPR"
     exon            519..1577
                     /gene="Ap5s1"
                     /gene_synonym="RGD1561852"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aatgggaccg acagtgggcg ggactcatgg tggcctgggg taatgacgtg ttctgctagc
       61 agaaaggtga ccagaggtca aggtctgcaa atctaggttc tcttcctgaa gcgcgtttgc
      121 caaatttcct gttgggtaac tttaaattct tggtcttagc cgtgtttaaa cactgtatct
      181 cctcagcctt gagaccccgg ggccgccact ctcacgctgc ccagagcggc caggccctct
      241 ctgtgtacct gtggctaact cgaattcctg tgctcttgcc tccgcctccc gagggttggg
      301 atttcaggtc tccggcttct ctggagaacc caccctggag ctatggtcca cgctttcctc
      361 atccacacgt taagggcccc gaatttggaa gatacaggcc tttgccgagt gctctactcc
      421 tgtgtctttg gtgctgagaa atcacctgat gatccccgac cacatggtgc agaaagggac
      481 aggctcttcc gaaaggaaca gattttggcg gtggccagac aggtggagtc actgtgtagg
      541 ctgcagcagc aagcatctgg atgttcctcc acagacccgc agcctcagtt ctcagctgag
      601 tctgtgtccc tgcatgaggc ccctcacgga gccttccacc tggcagctgg ggaccctttc
      661 caggagccac agacagtgct atggctgggc gtgctctcct taggtttcac cctggtgttg
      721 gatacccatg agaatctgct gctagctgag cgcacactcc ggctcttggc ccgcctcctc
      781 cttgaccacc tccggctgct gacaccaggt accaacttct tgttgcgggc tgaccgtatt
      841 gaggggatcc tcacccgctt cctgccacac gggcagctgc ttttcctcaa tgaccagttc
      901 gtccaggatc tggagaagga attcagtgct gcttggcccc gctgacccct caccagaatg
      961 aggcttctgg aaaggacaaa gaggcagggt aagattgcat actgctaagg gaagcttggc
     1021 gtctgcctct tgcccagtct gctccctact ctgacatgtg gccacactca ggacatatgg
     1081 attgggcaag cccacaggaa gggacctgga tagaaggatg tctgtgcctg ttctcaggcc
     1141 actggaattg ttgaacatcc tgaacctgga gctgccctgt ggcctcttag actctgcagt
     1201 gtccaccatg tccttgactc tagctccctt cagccctcca gctgtgagta ctggagcagt
     1261 gtactgcctg ccagactcac cttagtcgat agctacagca cagaaggagt ctctcagacc
     1321 ctcttcaagg ttgggaagct gccctggttc ctgcctttgc acatgagcaa ggattttgtc
     1381 agcaaggcct gttctgcatc catctccacc acagtgtgga gcagggggat tcttcttatt
     1441 cttgtttctt ctgtaccaag cctgtgtctg ccaggacagc tgagagcaca acagcttttc
     1501 ttgtctgctg gccagcagat gccaggcatc tgggccaggt gatgtcttat tttgaagtaa
     1561 aaacaatggc ggtctga
//
