LOCUS       NM_001191742            3448 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus adaptor related protein complex 4 subunit epsilon
            1 (Ap4e1), mRNA.
ACCESSION   NM_001191742 XM_230571
VERSION     NM_001191742.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3448)
  AUTHORS   Dell'Angelica,E.C., Mullins,C. and Bonifacino,J.S.
  TITLE     AP-4, a novel protein complex related to clathrin adaptors
  JOURNAL   J Biol Chem 274 (11), 7278-7285 (1999)
   PUBMED   10066790
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Jul 17, 2010 this sequence version replaced XM_230571.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.13331.1,
                                           SRR26643298.18349.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-147               JAXUCZ010000003.1  134726338-134726484
            148-219             JAXUCZ010000003.1  134729202-134729273
            220-343             JAXUCZ010000003.1  134733301-134733424
            344-417             JAXUCZ010000003.1  134739266-134739339
            418-539             JAXUCZ010000003.1  134748425-134748546
            540-699             JAXUCZ010000003.1  134754376-134754535
            700-866             JAXUCZ010000003.1  134755695-134755861
            867-940             JAXUCZ010000003.1  134760678-134760751
            941-1063            JAXUCZ010000003.1  134763692-134763814
            1064-1173           JAXUCZ010000003.1  134763918-134764027
            1174-1313           JAXUCZ010000003.1  134766446-134766585
            1314-1426           JAXUCZ010000003.1  134767148-134767260
            1427-1545           JAXUCZ010000003.1  134767345-134767463
            1546-1848           JAXUCZ010000003.1  134769999-134770301
            1849-1963           JAXUCZ010000003.1  134773153-134773267
            1964-2087           JAXUCZ010000003.1  134775977-134776100
            2088-2346           JAXUCZ010000003.1  134783592-134783850
            2347-2883           JAXUCZ010000003.1  134784682-134785218
            2884-3074           JAXUCZ010000003.1  134786723-134786913
            3075-3232           JAXUCZ010000003.1  134788116-134788273
            3233-3448           JAXUCZ010000003.1  134789873-134790088
FEATURES             Location/Qualifiers
     source          1..3448
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36"
     gene            1..3448
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /note="adaptor related protein complex 4 subunit epsilon
                     1"
                     /db_xref="GeneID:311404"
                     /db_xref="RGD:1562199"
     CDS             1..3393
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /note="adaptor-related protein complex AP-4, epsilon 1;
                     adaptor-related protein complex 4, epsilon 1 subunit"
                     /codon_start=1
                     /product="AP-4 complex subunit epsilon-1"
                     /protein_id="NP_001178671.1"
                     /db_xref="GeneID:311404"
                     /db_xref="RGD:1562199"
                     /translation="MSDMVERTLTALPGLFLQNQLGGPAASRAPFFSRLGGLIRGVTA
                     LSSKHEEEKLIQQELSSLKATVSAPTTTLKMMKECMVRLIYCEMLGYDASFGYIHAIK
                     LAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMALTVVSQIF
                     PREMIPAVLPLIEEKLQHSKEIIRRKAVLALYKFYLIAPNQVQHIHTKFRKALCDRDV
                     GVMAASLHIYLRMIKENSSGYKDLTESFVTILKQVVGGKLPVEFSYHSVPAPWLQIQL
                     LRILGLLGKDDERTSELMYDVLDESLRRAELNHNVTYAILFECVHTIYSIYPKSELLE
                     KAAKCIGKFVLSPKINLKYLGLKALTYVIQQDPSLALQHQITIIECLDHPDPIIKRET
                     LELLYRITNAQNVVVIVQKMLEYLHQSKEEYIIINLVGKIAELAEKYAPDNVWFIQTM
                     NAVFSVGGDVMHPDILSNFLRLLAEGFDDETEDQQLRLYAVQSYLTLLDMENTFYPQR
                     FLQVMSWVLGEYSYLLDRESPEAVMTRLYKLLRSDSISSETKAWLFAAVTKLTPQAHS
                     SPIVENLIQEFTVSLNTCLRQHAFELKHLHENEELMKSLLQSAQNCDDIMADASLSFL
                     DGFVAEGLSQGAAPYKPRHQRQEEQLSQEKVLNFEPYGLSFSSSGFTGRQSPAGVSLG
                     SDISGNSAETGLKEAGSLKMDGIKKLWGKEGYLPKKESGAADKLEAAHAPAESAMMEN
                     VDQAMTRKDQAQGHTPSTEEKEKQLLASSLFVGLGPENTINLLGKADVVSYKFRRKSK
                     PKVAQSDKMPSAHAAPSSTLSPVSDVAGGDEDSLSAADRGDGELGSELLGSESVLELP
                     SVENLSSVSLPVSSLFAGNDMEVFHPPSSSATSAVKEVSLAALLEETPECRRSALVEI
                     CSNETVAVSSYKVWKDECLLLVCSVTSKTDSEFTDAQLEIFPLENFKIIEQPGCPSPV
                     MEAESTKSFQYGVQMESPCVEGTLSGFIKYQMMDTHPVQLEFSMNLSLLDFIRPLKIS
                     TEDFGKLWLSFANDVKQNIKISEPRVALASVLTELQQKLRLCVVDVIGSEGLLACKLL
                     PSTPCILHCRVHADVVALWFRSSSSVLSDCLSCHCQKVMQTS"
     exon            1..147
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            148..219
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            220..343
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            344..417
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            418..539
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            540..699
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            700..866
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            867..940
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1063
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1173
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            1174..1313
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            1314..1426
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1545
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1848
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            1849..1963
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            1964..2087
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            2088..2346
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            2347..2883
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            2884..3074
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            3075..3232
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
     exon            3233..3448
                     /gene="Ap4e1"
                     /gene_synonym="RGD1562199"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgagcgaca tggtggagag gacgctgacc gcactgccgg ggctcttctt gcagaaccag
       61 ctgggagggc ctgcggcctc cagagcaccc ttcttctcca ggctgggcgg cctcatccgt
      121 ggcgtcactg cgctctcatc caagcacgaa gaagagaagt taatccagca ggaactgagt
      181 agtctgaagg cgactgtttc tgctcctact acaacactga aaatgatgaa ggaatgtatg
      241 gtgagactta tatactgtga gatgcttgga tacgatgctt cttttggtta tatacatgca
      301 atcaagttgg cccaacaagg aaacctctta gaaaaaagag tgggttattt ggctgtttct
      361 ctgtttctac atgaaagtca tgaacttttg cttctccttg tgaatacagt ggtaaaggac
      421 ctgcagagca ctaatctggt agaagtgtgt atggcactca ctgtcgtcag ccagattttc
      481 cctcgagaaa tgattccagc tgtccttcca ctaatagaag agaaactcca acattctaag
      541 gagattatac gaagaaaagc agttctggca ttatacaaat tttatctcat tgcccctaat
      601 caagtacagc atatccatac taagtttcgg aaagcactct gtgacagaga tgttggggtc
      661 atggctgcct ctttgcatat ataccttagg atgattaagg aaaattcttc tggatataaa
      721 gacttgactg agagttttgt aacaatttta aagcaggtgg tggggggaaa gctccctgta
      781 gagttcagtt accacagtgt gccagcgcca tggttacaga ttcagctctt gagaatactg
      841 ggactgctgg gaaaagacga tgaaaggaca agtgaactaa tgtatgatgt tcttgatgaa
      901 tccttacgaa gagccgagtt aaatcacaat gtcacttacg ctattctgtt tgagtgtgta
      961 cacacaatct attctattta tcctaaatca gaattacttg agaaggctgc caagtgcatt
     1021 ggaaaatttg ttctgtcacc taaaataaac ctcaaatatt taggactgaa ggctcttacc
     1081 tatgttatcc agcaggatcc ttctctggct cttcaacacc agataaccat aattgaatgc
     1141 ctagaccacc ctgatcccat tattaaaaga gagactctgg aacttcttta cagaattaca
     1201 aatgcacaga atgtagtagt tattgtacag aaaatgcttg aatatttaca tcagagcaaa
     1261 gaagagtaca tcatcatcaa cttagtcggc aaaatagctg aattggctga gaaatatgct
     1321 cctgacaacg tgtggttcat tcagacgatg aatgctgtgt tttcagtggg aggagatgta
     1381 atgcacccag acattctcag taactttctg agactgctag cagaaggttt tgatgatgaa
     1441 acagaagatc aacagttaag actctatgca gttcagtctt acctcacctt actagacatg
     1501 gaaaacactt tctatccaca gagatttctt caagttatga gttgggtatt aggagagtat
     1561 tcctacctct tagatagaga aagccccgag gcagttatga ccaggctcta caagttactg
     1621 aggagtgact ccatttcttc agaaacgaaa gcatggttgt ttgctgcagt aaccaagtta
     1681 acacctcaag ctcattcttc tcccatagtt gagaacttaa tccaagaatt cactgtatcc
     1741 ttgaatactt gtctgagaca acatgcattt gaattgaaac atctacatga aaatgaagag
     1801 cttatgaaga gcttgcttca gagtgctcag aattgtgacg acatcatggc agatgcttct
     1861 ttatcttttc tggatggttt tgtggctgaa ggactcagtc agggagcagc accttataag
     1921 ccccgtcacc agcgccaaga ggagcagctc tctcaggaaa aagttctcaa ttttgaacca
     1981 tatggactat cattttcttc atctggcttc actggacgac agtctcctgc tggcgtttct
     2041 ctgggctcag atatatctgg aaacagtgct gaaacagggc tgaaagaggc aggtagcctg
     2101 aagatggacg gcataaagaa attatggggt aaagaaggtt atctccccaa gaaggagagt
     2161 ggagctgctg ataaactgga agccgcacat gctcctgcag agagtgcaat gatggagaat
     2221 gtagaccaag ccatgactag gaaggaccaa gctcaaggcc acaccccttc tacagaggag
     2281 aaagaaaagc agctgttggc atcatcgctg tttgttgggc taggaccaga aaatacgatc
     2341 aatttgttgg gaaaagcaga tgttgtgtct tacaagttca ggaggaagtc aaaacccaag
     2401 gtagcccaaa gtgacaagat gcccagcgct catgccgctc cctcctccac ccttagccct
     2461 gtgtccgatg tggctggggg ggatgaggac agtctgagcg ctgcggatag aggagacggg
     2521 gagcttggtt cagagctgtt gggttctgag tctgtcttgg agctgccctc agttgaaaac
     2581 ctctcgagtg tcagcttgcc cgtgtcttct ttgtttgcgg gtaacgacat ggaagtattt
     2641 catccccctt catcctctgc aacttcagcc gtcaaggaag tcagtttggc tgctctgttg
     2701 gaagaaactc ctgaatgcag gcgttcagct ctcgtggaaa tctgtagtaa tgaaactgtg
     2761 gctgtgtctt cttacaaagt ctggaaggat gagtgtttat tgctggtgtg ctcagtcact
     2821 agtaagactg attcagagtt cacagatgct caattagaaa tttttccttt ggaaaatttc
     2881 aagatcattg agcagcctgg atgtccttca cctgtgatgg aagcagaaag caccaaatcc
     2941 ttccaatatg gcgtgcagat ggaaagccct tgtgtagagg ggactctctc tggttttata
     3001 aagtatcaaa tgatggatac acatcctgtt caactggaat tttccatgaa cttatcacta
     3061 ctagatttta ttaggccatt aaagatctca actgaagact ttggcaaact ctggttgtct
     3121 tttgcaaatg atgtgaagca aaatataaaa atatcagagc ctcgagttgc actggcttct
     3181 gtcctgacag agctgcagca gaaactcaga ctttgcgtgg ttgacgtcat aggcagtgaa
     3241 ggtctgctgg cctgtaagct gcttccgtcc accccctgta tcctgcactg ccgagtacac
     3301 gctgacgtgg tagccctgtg gttccgatcc tctagctctg ttctttcaga ctgtttatct
     3361 tgtcactgtc agaaagtgat gcagacatcc tagcaaagtt ctgttaagtt ttactttttt
     3421 cacataaatg gtttacattt acaacctt
//
