LOCUS       NM_133593               3184 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus adaptor related protein complex 3 subunit mu 1
            (Ap3m1), mRNA.
ACCESSION   NM_133593
VERSION     NM_133593.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3184)
  AUTHORS   Mardones,G.A., Burgos,P.V., Lin,Y., Kloer,D.P., Magadan,J.G.,
            Hurley,J.H. and Bonifacino,J.S.
  TITLE     Structural basis for the recognition of tyrosine-based sorting
            signals by the mu3A subunit of the AP-3 adaptor complex
  JOURNAL   J Biol Chem 288 (13), 9563-9571 (2013)
   PUBMED   23404500
  REMARK    GeneRIF: Structural basis for the recognition of tyrosine-based
            sorting signals by the mu3A subunit of the AP-3 adaptor complex
REFERENCE   2  (bases 1 to 3184)
  AUTHORS   Bultema,J.J., Ambrosio,A.L., Burek,C.L. and Di Pietro,S.M.
  TITLE     BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and
            Rab32 proteins to mediate protein trafficking to lysosome-related
            organelles
  JOURNAL   J Biol Chem 287 (23), 19550-19563 (2012)
   PUBMED   22511774
REFERENCE   3  (bases 1 to 3184)
  AUTHORS   Larimore,J., Tornieri,K., Ryder,P.V., Gokhale,A., Zlatic,S.A.,
            Craige,B., Lee,J.D., Talbot,K., Pare,J.F., Smith,Y. and Faundez,V.
  TITLE     The schizophrenia susceptibility factor dysbindin and its
            associated complex sort cargoes from cell bodies to the synapse
  JOURNAL   Mol Biol Cell 22 (24), 4854-4867 (2011)
   PUBMED   21998198
REFERENCE   4  (bases 1 to 3184)
  AUTHORS   Taneichi-Kuroda,S., Taya,S., Hikita,T., Fujino,Y. and Kaibuchi,K.
  TITLE     Direct interaction of Dysbindin with the AP-3 complex via its mu
            subunit
  JOURNAL   Neurochem Int 54 (7), 431-438 (2009)
   PUBMED   19428785
REFERENCE   5  (bases 1 to 3184)
  AUTHORS   Schroder,B., Wrocklage,C., Pan,C., Jager,R., Kosters,B.,
            Schafer,H., Elsasser,H.P., Mann,M. and Hasilik,A.
  TITLE     Integral and associated lysosomal membrane proteins
  JOURNAL   Traffic 8 (12), 1676-1686 (2007)
   PUBMED   17897319
REFERENCE   6  (bases 1 to 3184)
  AUTHORS   Pevsner,J., Volknandt,W., Wong,B.R. and Scheller,R.H.
  TITLE     Two rat homologs of clathrin-associated adaptor proteins
  JOURNAL   Gene 146 (2), 279-283 (1994)
   PUBMED   8076832
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC070925.1.
            
            On Jun 20, 2004 this sequence version replaced NM_133593.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC070925.1, L07073.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3184
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p16"
     gene            1..3184
                     /gene="Ap3m1"
                     /gene_synonym="P47a"
                     /note="adaptor related protein complex 3 subunit mu 1"
                     /db_xref="GeneID:171126"
                     /db_xref="RGD:620417"
     exon            1..27
                     /gene="Ap3m1"
                     /gene_synonym="P47a"
                     /inference="alignment:Splign:2.1.0"
     exon            28..303
                     /gene="Ap3m1"
                     /gene_synonym="P47a"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..1287
                     /gene="Ap3m1"
                     /gene_synonym="P47a"
                     /note="mu3A-adaptin; HA1 47 kDa subunit homolog 1; AP-3
                     adapter complex mu3A subunit; golgi adaptor AP-1 47 kDa
                     protein homolog 1; adaptor-related protein complex 3, mu 1
                     subunit; clathrin coat assembly protein AP47 homolog 1;
                     adapter-related protein complex 3 mu-1 subunit; clathrin
                     coat-associated protein AP47 homolog 1; clathrin assembly
                     protein assembly protein complex 1 medium chain homolog 1;
                     adaptor-related protein complex AP-3, mu 1 subunit;
                     clathrin-associated adaptor protein homolog (p47A);
                     Mu-adaptin 3A; adapter-related protein complex 3 subunit
                     mu-1; AP-3 adaptor complex mu3A subunit; clathrin assembly
                     protein assembly protein complex 3 mu-1 medium chain"
                     /codon_start=1
                     /product="AP-3 complex subunit mu-1"
                     /protein_id="NP_598277.2"
                     /db_xref="GeneID:171126"
                     /db_xref="RGD:620417"
                     /translation="MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVEN
                     VPPVISTPHHYLISIYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAI
                     KDNVVIVYELLEEMLDNGFPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTG
                     QLSNIPWRRAGVKYTNNEAYFDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDL
                     SLSFMNPRLLDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYV
                     KHNISFKENSSCGRFDITIGPKQNMGKTIEGITVTVHMPKVVLNMNLTPTQGSYTFDP
                     VTKVLAWDVGKITPQKLPSLKGLVNLQSGAPKPEENPNLNIQFKIQQLAISGLKVNRL
                     DMYGEKYKPFKGVKYITKAGKFQVRT"
     exon            304..475
                     /gene="Ap3m1"
                     /gene_synonym="P47a"
                     /inference="alignment:Splign:2.1.0"
     exon            476..613
                     /gene="Ap3m1"
                     /gene_synonym="P47a"
                     /inference="alignment:Splign:2.1.0"
     exon            614..699
                     /gene="Ap3m1"
                     /gene_synonym="P47a"
                     /inference="alignment:Splign:2.1.0"
     exon            700..833
                     /gene="Ap3m1"
                     /gene_synonym="P47a"
                     /inference="alignment:Splign:2.1.0"
     exon            834..1041
                     /gene="Ap3m1"
                     /gene_synonym="P47a"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1186
                     /gene="Ap3m1"
                     /gene_synonym="P47a"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..3160
                     /gene="Ap3m1"
                     /gene_synonym="P47a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaatcactga ctcgcccagg tgtcgggaaa atgatccaca gtctatttct catcaactgt
       61 tctggcgaca tatttctaga aaaacactgg aagagcgttg taagccaatc tgtgtgtgac
      121 tatttctttg aagctcagga gaaagctgct gatgttgaaa atgtaccacc tgtcatttca
      181 acacctcacc actacctcat tagtatctac cgggataagc tcttctttgt gtctgtgata
      241 cagactgaag tgccacctct ctttgtaatt gagtttctgc atcgagttgc tgacactttt
      301 caggactact ttggtgagtg ttcagaggct gcaattaagg ataatgtggt catagtgtat
      361 gagctcttgg aagaaatgtt agacaatgga ttcccactgg ctaccgaatc taacattctg
      421 aaagaactga ttaaaccacc aacaattcta cgttctgtcg tcaattctat tacaggcagt
      481 agtaatgttg gggacacgct ccccactggg cagctgtcca acatcccgtg gcgtcgagca
      541 ggtgtaaagt acaccaacaa tgaagcctac tttgatgtag tcgaagagat agatgcgatt
      601 atagataaat caggatctac agtctttgca gaaattcaag gtgtcattga tgcttgcatt
      661 aagctgtctg gaatgcctga tctctctctc tctttcatga acccaaggct tctagatgat
      721 gtcagcttcc acccatgcat ccggttcaaa cgctgggaat ctgagagagt tttgtcattc
      781 attcctcccg atggaaattt ccgactcata tcataccgcg tcagctcaca aaatctagtg
      841 gcaatcccag tgtatgtgaa acataatatc agctttaagg aaaacagctc ttgtggtaga
      901 tttgatataa caattggacc aaaacagaat atgggaaaaa cgattgaagg aatcacagtg
      961 actgttcaca tgccaaaagt tgtgctgaat atgaacctga caccaacaca aggcagctat
     1021 acattcgatc cagtcaccaa ggtactagca tgggatgtgg ggaaaattac tccacaaaag
     1081 ctcccaagtc ttaaaggact ggtaaattta cagtcaggag cacccaagcc agaagagaac
     1141 ccaaacctca acatacagtt caagatccag cagcttgcta tttcaggctt aaaagtgaac
     1201 cgcttggaca tgtatggtga gaagtataag ccatttaaag gagtcaagta tatcacaaag
     1261 gccggaaagt tccaagtgag gacatgagaa gaggccagac ttgctcaaga tcagtttgtt
     1321 ttgcaagtgt cattgcggtt tcttactatt aggtaccaag tgggtgggaa taatatagag
     1381 catctgggtc aagctaccct gctaacaaag ttgcttagta atgatgtagg ctcctcagga
     1441 gctttaagct aaggaaagtt ttctaaagac ttagcttatt ttgtatcttt tcacttagga
     1501 aaaggtttag gtgatttttt tccatggggg ccaccagctg aatgctgccc atggtaacag
     1561 tcaaggcaga aggctacagt gataacctct ctcctaaagc aagtgaactg gtctcatctt
     1621 ccagcaggaa ctgtctcagt ctatgaggtg tcagctgtag ccaagggtca caccttctga
     1681 tcttagccat ctcaatcagt gtctgtccca agagaggaga ttgccccacc ccaagaagtt
     1741 tacagaaaac tgcctcttca agtgtttgcc ttactcagct tttcacttgt gccattaagc
     1801 aagcactgta gcaaaagcca cttccacatg gcccaggcag ggagccctgc agctccatgc
     1861 tccattctca ctgtacttgg tattatattt tttataaata agatttttat gtaaagctca
     1921 gattttgatt tacaaggacc ttgctgcagt aaatattcca tcaatcttgt gccaccagtt
     1981 cagctgttag atagcacagt caaatcattt gcatcaaaag ggcaaatact ttattaagat
     2041 aatgaaaggg aacactactt ctgctgttag gcacaagtgt ctgtgctttt aaacaaattc
     2101 aagtagtaaa agagaaaatc aagcaaaacc tttgccattc tcgtgtttta ttaaagcttt
     2161 atttggtgcc actaacctag ttagcttgaa accccagttt aacaaaggga aggaaacatg
     2221 catttcactg ttactcttct ccatctttta tgctgttgtt cttaagtagt tgagtttgcc
     2281 tgtgtgcctg cagagcgcct tttcgtacac catacattgc aaggccaagg ggataacacc
     2341 ttctccaaac tgtcaaatgt ggaggaagca cttagtgtgt ctgctgaact gtgtacatgg
     2401 aaacagtaac aatttatact aattgatctt tacacttgga agccggtcct tctgcgtctt
     2461 cgtttggaaa tccttgtgca gtgattttgc ctcatcacac aaaagaaaat ggaggaagac
     2521 aaaaatggtc gcccttccta gccccttgtc ctttgtcctt ccttcccttg ctaggtcacg
     2581 tcctaggccc gctccatgtt ggagtgccaa cgatgcggta gctctgctgc tgtggcccca
     2641 tctaacaagg ccaactgttg caaaacttca aggagacact tcttgagtaa ccaactgatt
     2701 gacaatttta agtcaaaata caaaatatct attccctttg actaagattg gttatccact
     2761 tctagtttta cgatcttgtt ccacctccaa agcaatcaca ccagttctag ttcttcacag
     2821 ttctttacct cacaaccata cctagaacgc acagcttcct tgctgtgcag tcctcttgtc
     2881 tgtcagagta gagtatatac caagtgtctt gtgtccagga atttctgcta aagtagctaa
     2941 tcagactgca ttcctttact gttaagttgt tgtatttatt aatttgacag aactcaataa
     3001 gccctttctc tagttctgac cataatgtca ataaatatat gagagcaacc cactgatttt
     3061 taggtttgat tgttagtgga atagtctcat attcaggctg tattaaccgg ctacactgga
     3121 tgagtttctt ctgtatcata aagtgttaca gttgcctgaa aaaaaaaaaa aaaaaaaaaa
     3181 aaaa
//
