LOCUS       NM_001100719            4793 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus adaptor related protein complex 3 subunit delta 1
            (Ap3d1), mRNA.
ACCESSION   NM_001100719 XM_001076208 XM_234908
VERSION     NM_001100719.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4793)
  AUTHORS   Asensio,C.S., Sirkis,D.W., Maas,J.W. Jr., Egami,K., To,T.L.,
            Brodsky,F.M., Shu,X., Cheng,Y. and Edwards,R.H.
  TITLE     Self-assembly of VPS41 promotes sorting required for biogenesis of
            the regulated secretory pathway
  JOURNAL   Dev Cell 27 (4), 425-437 (2013)
   PUBMED   24210660
REFERENCE   2  (bases 1 to 4793)
  AUTHORS   Matsuda,S., Kakegawa,W., Budisantoso,T., Nomura,T., Kohda,K. and
            Yuzaki,M.
  TITLE     Stargazin regulates AMPA receptor trafficking through adaptor
            protein complexes during long-term depression
  JOURNAL   Nat Commun 4, 2759 (2013)
   PUBMED   24217640
REFERENCE   3  (bases 1 to 4793)
  AUTHORS   Bultema,J.J., Ambrosio,A.L., Burek,C.L. and Di Pietro,S.M.
  TITLE     BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and
            Rab32 proteins to mediate protein trafficking to lysosome-related
            organelles
  JOURNAL   J Biol Chem 287 (23), 19550-19563 (2012)
   PUBMED   22511774
REFERENCE   4  (bases 1 to 4793)
  AUTHORS   Cheung,G. and Cousin,M.A.
  TITLE     Adaptor protein complexes 1 and 3 are essential for generation of
            synaptic vesicles from activity-dependent bulk endosomes
  JOURNAL   J Neurosci 32 (17), 6014-6023 (2012)
   PUBMED   22539861
REFERENCE   5  (bases 1 to 4793)
  AUTHORS   Larimore,J., Tornieri,K., Ryder,P.V., Gokhale,A., Zlatic,S.A.,
            Craige,B., Lee,J.D., Talbot,K., Pare,J.F., Smith,Y. and Faundez,V.
  TITLE     The schizophrenia susceptibility factor dysbindin and its
            associated complex sort cargoes from cell bodies to the synapse
  JOURNAL   Mol Biol Cell 22 (24), 4854-4867 (2011)
   PUBMED   21998198
REFERENCE   6  (bases 1 to 4793)
  AUTHORS   Falcon-Perez,J.M. and Dell'Angelica,E.C.
  TITLE     Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect
            of adaptor protein 3-depleted fibroblasts by promoting zinc
            accumulation in lysosomes
  JOURNAL   Exp Cell Res 313 (7), 1473-1483 (2007)
   PUBMED   17349999
REFERENCE   7  (bases 1 to 4793)
  AUTHORS   Theos,A.C., Tenza,D., Martina,J.A., Hurbain,I., Peden,A.A.,
            Sviderskaya,E.V., Stewart,A., Robinson,M.S., Bennett,D.C.,
            Cutler,D.F., Bonifacino,J.S., Marks,M.S. and Raposo,G.
  TITLE     Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting
            from endosomes to melanosomes
  JOURNAL   Mol Biol Cell 16 (11), 5356-5372 (2005)
   PUBMED   16162817
REFERENCE   8  (bases 1 to 4793)
  AUTHORS   Salazar,G., Craige,B., Love,R., Kalman,D. and Faundez,V.
  TITLE     Vglut1 and ZnT3 co-targeting mechanisms regulate vesicular zinc
            stores in PC12 cells
  JOURNAL   J Cell Sci 118 (Pt 9), 1911-1921 (2005)
   PUBMED   15860731
REFERENCE   9  (bases 1 to 4793)
  AUTHORS   Elewaut,D., Lawton,A.P., Nagarajan,N.A., Maverakis,E., Khurana,A.,
            Honing,S., Benedict,C.A., Sercarz,E., Bakke,O., Kronenberg,M. and
            Prigozy,T.I.
  TITLE     The adaptor protein AP-3 is required for CD1d-mediated antigen
            presentation of glycosphingolipids and development of Valpha14i NKT
            cells
  JOURNAL   J Exp Med 198 (8), 1133-1146 (2003)
   PUBMED   14557411
REFERENCE   10 (bases 1 to 4793)
  AUTHORS   Blumstein,J., Faundez,V., Nakatsu,F., Saito,T., Ohno,H. and
            Kelly,R.B.
  TITLE     The neuronal form of adaptor protein-3 is required for synaptic
            vesicle formation from endosomes
  JOURNAL   J Neurosci 21 (20), 8034-8042 (2001)
   PUBMED   11588176
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC169097.1.
            
            On or before Sep 7, 2008 this sequence version replaced
            XM_234908.4, XM_001076208.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC169097.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4793
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..4793
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /note="adaptor related protein complex 3 subunit delta 1"
                     /db_xref="GeneID:314633"
                     /db_xref="RGD:1308659"
     exon            1..332
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     CDS             237..3851
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /note="adaptor-related protein complex 3, delta subunit;
                     adaptor-related protein complex 3, delta 1 subunit"
                     /codon_start=1
                     /product="AP-3 complex subunit delta-1"
                     /protein_id="NP_001094189.1"
                     /db_xref="GeneID:314633"
                     /db_xref="RGD:1308659"
                     /translation="MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIK
                     QELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRVGYLAASQCF
                     HEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKP
                     YIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNY
                     LSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLL
                     YECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTH
                     PKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTY
                     RDELLTKIIDICSQSNYQHITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKA
                     IRKFAVSQMSSLLDSAHLVASSTQRNGICEVLYAAAWICGEFSEHLQGPQQTLEAMLR
                     PKVTTLPGHIQAVYVQNVVKLYASILQQKEQAADTEGAQEVTQLLVERLPQFVQSADL
                     EVQERASCILQLVKHVQKLQAKGVPVAEEVSALFAGELNPVAPKAQKKVPVPEGLDLD
                     AWINEPPSDSESEDEKPKAIFHEEEPRHTRRRQPEEDEEELARRREARKQEQANNPFY
                     IKSSPSPQKRYQDAPGVEHIPVVQIDLSVPLKVPGMPMSDQYVKLEEQRRHRQRLEKD
                     KKRKKKEKGKRRHSSLPTESDEDIAPAQRVDIITEEMPENALPSDEDDKDPNDPYRAL
                     DIDLDKPLADSEKLPVQKHRNAETVKSPEKEGVPGVEKKSKKPKKKEKKPKEREREKK
                     DKKGEDLDFWLSTTPPPAAAPVPAPSTEGLAASIVTPPKGECEVLKGEEPQDEEDHMD
                     HDQERKSSRHKKKKHRKEKEERPRDKKKAKRKQVVQLENGAPAEEEEEEEEPIPPMSS
                     YCLLAENPYIKVTYDVQASLQKDSQVTVSIILENQSSSFLKNMELNVLDSLNTKMARP
                     EGSSVHDGVPVPFQLPPGVSNEAQFVFTIQSIVMAQKLKGTLSFIAKDDEGATHEKLD
                     FRLHFSCSSYLITTPCYSDAFAKLLESGDLSMNSIKVDGISISFQNLLAKICFYHHFS
                     VVERVDSCASMYSRSIQGHHVCLLVKKGESSVSVDGKCSDATLLSSLLEEMKTTLSQC
                     "
     exon            333..428
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            429..509
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            510..590
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            591..698
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            699..828
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            829..968
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1042
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1092
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1142
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1191
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            1192..1337
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..1717
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            1718..1949
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            1950..2095
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            2096..2237
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            2238..2309
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            2310..2385
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            2386..2573
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            2574..2647
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            2648..2813
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            2814..2885
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            2886..2993
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            2994..3140
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            3141..3188
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            3189..3378
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            3379..3467
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            3468..3553
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            3554..3675
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            3676..3755
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
     exon            3756..4766
                     /gene="Ap3d1"
                     /gene_synonym="Ap3d"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atttgcgggt ggccctgagc agggaagggt ctgcggaagc gggggctaac tcgctgcccc
       61 ttctcctcag actggtctcc ggccacagcc gtcgctctgg cctccacgtc gtcctctccg
      121 cggcggccgg aaacgcagcg gggcggtcgc ctgaggtgcg gtcgccgggt ccccgcacct
      181 cccagggccg cggcggcggc gttcccctcg gaggccacag cccacgggcc gccgcgatgg
      241 ccctcaagat ggtcaagggc agtatcgacc gcatgttcga caagaacctg caggatctgg
      301 tccgcggcat ccgcaaccac aaggaggacg aggccaagta catctcccag tgcattgacg
      361 agatcaagca ggaactcaag caggacaaca ttgctgtgaa ggccaacgct gtctgcaagc
      421 tcacctactt acagatgctc gggtacgaca tcagctgggc tgccttcaac atcattgaag
      481 tcatgagtgc ctccaagttc acattcaagc gtgtcggcta ccttgcagcc tctcagtgct
      541 tccatgaagg tactgacgtc atcatgctga ccactaacca gatccgaaag gacctgagca
      601 gccctagcca gtacgacact ggagtggcac tgactggtct gtcctgtttt gtcaccccag
      661 atcttgccag agacctggca aatgacatca tgaccctgat gtctcacacg aagccataca
      721 tcaggaagaa ggcagtgctg atcatgtaca aagtgttcct caagtaccct gagtcactgc
      781 gtcctgcctt tccccggctt aaggagaagc tggaggaccc agacccaggg gtgcagtctg
      841 cagctgtcaa tgtcatctgt gagctagcgc gccgaaaccc taaaaactac ctgtctctgg
      901 ctccactgtt tttcaagctc atgacatcct ctaccaacaa ctgggtcctc atcaagatca
      961 tcaaactgtt cggtgccctg actcccctgg agcccaggct gggcaagaag ctgatcgagc
     1021 ctctcaccaa cctcattcac agcacctctg ccatgtccct gctgtacgag tgtgtgaaca
     1081 ccgtgattgc tgtgctcatc tcactgtctt ccgggatgcc caaccacagc gccagcatcc
     1141 agctatgcgt tcagaagttg aggatactga tagaggactc cgaccagaac ttaaagtacc
     1201 tggggctgct ggccatgtct aaaatcctga agacacatcc caagtctgtg caatcccaca
     1261 aggacctgat cctgcagtgc ctggatgaca aagacgagtc catccgcctg cgtgcccttg
     1321 acctgctcta tggaatggtg tccaaaaaga acctgatgga aattgtgaag aagcttatga
     1381 cccacgtgga caaggccgag ggcaccacct atcgtgacga gctgctcacc aagatcattg
     1441 acatctgtag ccagtccaac taccagcaca tcaccaactt cgagtggtac ataagcatcc
     1501 ttgtggagct gacaagactg gagggcaccc ggcatggtca cctcattgct gcacagatgc
     1561 tggacgtggc cattcgggtc aaggccattc gaaaatttgc tgtgtcccag atgtcttcgc
     1621 tgcttgatag tgcccacctg gtagccagca gcacccaacg caacggcatc tgtgaggtgc
     1681 tctatgctgc tgcctggatc tgcggggagt tctcggagca cctacagggg ccccagcaaa
     1741 ccctggaggc catgctgcgg cccaaggtca ccacactgcc cggccacatc caggctgtgt
     1801 atgtgcagaa cgtggtaaag ctgtacgcgt ccatcctgca gcagaaggag caggctgccg
     1861 acactgaggg ggcacaggag gtcacccagc tactagtgga gcggctgcca cagtttgtgc
     1921 agagcgccga cctggaggtg caggagcggg cgtcttgcat cctgcagctg gtcaagcatg
     1981 tacagaagct gcaagcaaaa ggcgtgccgg tggccgagga agtgagcgcc ttgtttgctg
     2041 gggaactgaa ccctgtggcc cccaaggccc agaagaaggt cccagttcct gaaggcctag
     2101 acctggatgc ctggatcaat gagccacctt cagacagtga gtctgaggat gagaaaccca
     2161 aggccatctt tcatgaagag gagccaaggc acacccggcg ccggcagcct gaggaggatg
     2221 aggaggagct ggcccggcgg cgagaggccc ggaagcagga gcaagccaac aatcccttct
     2281 acatcaagag ctccccatcc ccgcagaagc gataccaaga cgcaccaggc gtggagcaca
     2341 ttcctgtggt acagatcgac ctctccgtgc ctctgaaagt tccaggtatg cccatgtcag
     2401 accagtatgt gaagctggag gaacagcggc gacaccggca gcggctggag aaggacaaga
     2461 aaaggaagaa gaaggagaag ggcaagcgtc gccacagttc cctgcccacg gagagtgatg
     2521 aggacatcgc ccccgcccag cgtgtggaca tcatcactga ggagatgcct gagaatgctc
     2581 tgcctagtga tgaggatgac aaagacccca atgaccccta cagggcactg gacattgacc
     2641 tagataagcc cttggccgac agtgagaagc tgcctgtcca gaaacataga aacgcggaga
     2701 cagtgaagtc cccagagaag gagggtgtgc ctggggtgga gaagaagagc aagaagccca
     2761 agaagaagga gaagaagccc aaagagagag aaagggagaa gaaggacaag aagggtgagg
     2821 acttagactt ctggctgtcc accaccccgc cacctgctgc tgcccccgtc cctgccccat
     2881 ctacggaagg acttgctgcg agcattgtca ccccccctaa gggtgagtgt gaggttctca
     2941 aaggggaaga gccccaggac gaggaggacc acatggatca tgaccaagaa aggaaatcat
     3001 cccggcacaa gaagaagaaa cacaggaagg agaaggagga gaggccacga gacaaaaaga
     3061 aagccaagag gaagcaggtg gtgcagctag agaatggtgc gccagcagag gaggaagagg
     3121 aggaggagga acctatcccg cccatgtcca gttactgcct tctggctgag aatccgtaca
     3181 ttaaagtgac atatgacgtc caagccagct tacagaagga cagccaagtg actgtgtcta
     3241 tcatcctgga gaatcagagc agcagcttcc tgaagaacat ggaactcaac gtgctagact
     3301 cactcaacac caagatggcc aggccagagg gctcatcagt gcatgatggt gtgcctgtgc
     3361 ctttccagct gccccccggc gtctccaatg aggcccagtt tgtgttcacc attcagagca
     3421 tcgtcatggc ccagaagctc aaaggcacgc tgtccttcat tgccaaggat gatgaaggag
     3481 ccacccatga gaagttggac ttccggctgc atttcagctg tagctcgtac ctgatcacca
     3541 ccccctgcta cagcgatgcc tttgccaagt tgctggagtc aggagacctg agcatgaact
     3601 ccatcaaagt tgatggcatt agtatatctt tccagaatct tctggcaaag atctgcttct
     3661 accaccattt ttccgttgtg gagcgagtag actcctgcgc ctccatgtac agccgctcta
     3721 tccagggcca tcacgtctgc ctgctggtga agaagggtga gagctccgtg tcagtggacg
     3781 ggaagtgcag cgatgccacg ctgctcagca gcctgctgga ggaaatgaag accacgctgt
     3841 ctcagtgctg aattgcagag tccaggatgt acaagagaaa gatgtgatgg gtcttacctc
     3901 tcctttgtcg tgtactgtct ccacacccag cattaattta acacctccgg cctccgctgt
     3961 gtgacgcaga ggtcctgtgt tgcatcagct tcttttacta tcctttttca ctcctttggc
     4021 aaggaaggcc atcctgaccc ccagcaggaa cgggctgctc cacttcccgt tctcaaaggc
     4081 ggctgtggga tgtggcccca ctggtctgat cccgtgctgc ctctggagga acccttagag
     4141 ctgctgctgt cctcagatat cccaactggt ggcctctgaa gaggggctca gaccagctgt
     4201 taatgcttct cctcacagcc tacgaggccg gccggccgaa gtgtccttgt gggtatttcc
     4261 acagctcggc tgctgacagc agggatgatg tccctttgat tttcttctgt tccacagaat
     4321 tgtggtctgt cttgaggttc tgttgtgggg gtcagtggag gagtccaatg tatgcccctc
     4381 agtttgtcac tacacatcat gggcttgtcc ctgcagctgt ggagggctgg gtgccttgcg
     4441 gtggagggtg gcatcctggg aacattcagc gctcccccag ctgttcctgg acaaggtgaa
     4501 gagaccccat cctggacact tcctataact gggtagctgc gcacagctga gccctcctca
     4561 gaggtgacgg tggtctacac acattctggc gttcctttga ggataactgt cactttagca
     4621 tgtagagtac tcttaccgac cccacgtgac cttccggctc tatgatgttc catgattgat
     4681 ttgctgtcga cattcccatg tgaagagaga tatatcacgc tgctgacgat cagtgtcaca
     4741 atgacccatt aaagagtcaa aaaacaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
