LOCUS       NM_001127531            1838 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus adaptor related protein complex 1 subunit sigma 2
            (Ap1s2), mRNA.
ACCESSION   NM_001127531 XM_001068004 XM_217618
VERSION     NM_001127531.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1838)
  AUTHORS   Baltes,J., Larsen,J.V., Radhakrishnan,K., Geumann,C., Kratzke,M.,
            Petersen,C.M. and Schu,P.
  TITLE     sigma1B adaptin regulates adipogenesis by mediating the sorting of
            sortilin in adipose tissue
  JOURNAL   J Cell Sci 127 (Pt 16), 3477-3487 (2014)
   PUBMED   24928897
REFERENCE   2  (bases 1 to 1838)
  AUTHORS   Glyvuk,N., Tsytsyura,Y., Geumann,C., D'Hooge,R., Huve,J.,
            Kratzke,M., Baltes,J., Boening,D., Klingauf,J. and Schu,P.
  TITLE     AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling,
            learning and memory
  JOURNAL   EMBO J 29 (8), 1318-1330 (2010)
   PUBMED   20203623
  REMARK    Erratum:[EMBO J. 2010 Jun 2;29(11):1941. Boning, Daniel [corrected
            to Boening, Daniel]]
REFERENCE   3  (bases 1 to 1838)
  AUTHORS   Page,L.J., Sowerby,P.J., Lui,W.W. and Robinson,M.S.
  TITLE     Gamma-synergin: an EH domain-containing protein that interacts with
            gamma-adaptin
  JOURNAL   J Cell Biol 146 (5), 993-1004 (1999)
   PUBMED   10477754
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166480.1.
            
            On Jun 1, 2008 this sequence version replaced NM_001127531.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166480.1, FN803434.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1838
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq14"
     gene            1..1838
                     /gene="Ap1s2"
                     /gene_synonym="RGD1561862"
                     /note="adaptor related protein complex 1 subunit sigma 2"
                     /db_xref="GeneID:302671"
                     /db_xref="RGD:1561862"
     exon            1..122
                     /gene="Ap1s2"
                     /gene_synonym="RGD1561862"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..596
                     /gene="Ap1s2"
                     /gene_synonym="RGD1561862"
                     /note="adaptor-related protein complex 1, sigma 2 subunit"
                     /codon_start=1
                     /product="AP-1 complex subunit sigma-2"
                     /protein_id="NP_001121003.1"
                     /db_xref="GeneID:302671"
                     /db_xref="RGD:1561862"
                     /translation="MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPK
                     MCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDI
                     IFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT"
     exon            123..301
                     /gene="Ap1s2"
                     /gene_synonym="RGD1561862"
                     /inference="alignment:Splign:2.1.0"
     exon            302..410
                     /gene="Ap1s2"
                     /gene_synonym="RGD1561862"
                     /inference="alignment:Splign:2.1.0"
     exon            411..548
                     /gene="Ap1s2"
                     /gene_synonym="RGD1561862"
                     /inference="alignment:Splign:2.1.0"
     exon            549..1811
                     /gene="Ap1s2"
                     /gene_synonym="RGD1561862"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctccccgcgg caccacggct tcccttcaac agcctggcga cgggggcttc ccctcagcag
       61 ctgccggcgc ctcagtctcc gcagccagcc aagctccgcc gcgtccgcgg cccgcagccg
      121 ccatgcagtt tatgttgctt tttagtcgtc agggaaagct tcgactgcag aaatggtatg
      181 tcccactgtc agacaaagag aagaagaaaa tcaccagaga acttgtgcaa accgttttag
      241 cacggaaacc caagatgtgc agcttccttg agtggagaga tctgaagatt gtttataaaa
      301 gatatgccag tctatatttt tgctgtgcta ttgaggatca ggacaatgaa ctgattaccc
      361 tggaaataat ccatcgttat gtggaattac ttgacaagta ttttggcagt gtgtgtgaac
      421 ttgatatcat ctttaatttt gagaaggcct attttatttt ggatgaattt cttttgggag
      481 gagaagttca ggaaacatca aagaaaaatg tccttaaagc aattgagcag gctgatctcc
      541 tgcaggagga agctgaaacc ccacgtagtg ttcttgaaga aattggactg acataactgt
      601 cctcccttgc tgatgacttc ttgtggcatt tcacactgta gatggtcact gcctcccatg
      661 tccatgttag ctaacggtgt aagatgatgt cttgtcagta ttactgtttt gctaagctgc
      721 ttcattcagg cctacccaat tttttttaaa gggaactttg gttaatcaaa tgataaatga
      781 agggacataa atatgaatta ggaagatgta gaaaaagtaa cataccactt ctggacatct
      841 taaagtttaa aggtcagtct cataattatg tgcttatata aaaatatgtc tattacatgt
      901 atatccaaca atttggcaaa atatatttac aattgtactt caacaaggaa acttaaatta
      961 tgtgaaacct ggtttaatga aaccaaagac tagagtagca tttcagtata tataagaatg
     1021 aagggaattg acatatgaat gaaagtttat tgaaaattta agcaaccaaa tttctaccaa
     1081 agacccatat tagatacaac atacattaaa acaaaaggaa tatagatgct tttagaggac
     1141 tatcttagaa tgatgctgtt ttatactaaa attcattaag tattctgaat gaatgggaca
     1201 aggaacaaag actttcctaa tcttgagcac ataattttta aggccaagta acatttgatt
     1261 ccctgaggtg aagttttcgt ggtcataatc atgtagttgt ttttgatgcc ccaaataaaa
     1321 taggatggtt aattaccagg tattcttcat aatagtatgt tgctttcctc acagagtatt
     1381 acataaagtc attatctaaa gcatgatgtt ccttctaggg tgcttgttaa agccaaattt
     1441 attttgcttc cctattgctt ccttccagtt agaagtgctg cagacttgac agcagctccc
     1501 tatcctttca tgtcactgcc tagtcgtcgg aagtcttatg acagcttaaa agataccttt
     1561 cgtatagcaa agtgagagtt gactgaagca aagtggcatt ggttggccct atattttttg
     1621 aagctgtata aattcctggc atcactttta tacatcctga cacatacctg aacacatctc
     1681 cctgatttct atgttccctt gtaatatgct aggctggagt aagctttgct gtgattgtga
     1741 acaactttca agccacctga acactgtctt atcacatcac caattaatgg taataaatgt
     1801 tctgcaaaca caaaaaaaaa aaaaaaaaaa aaaaaaaa
//
