LOCUS       NM_001191850            2374 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus adaptor-related protein complex 1 associated
            regulatory protein (Ap1ar), mRNA.
ACCESSION   NM_001191850 XM_342338
VERSION     NM_001191850.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2374)
  AUTHORS   Maritzen,T., Zech,T., Schmidt,M.R., Krause,E., Machesky,L.M. and
            Haucke,V.
  TITLE     Gadkin negatively regulates cell spreading and motility via
            sequestration of the actin-nucleating ARP2/3 complex
  JOURNAL   Proc Natl Acad Sci U S A 109 (26), 10382-10387 (2012)
   PUBMED   22689987
REFERENCE   2  (bases 1 to 2374)
  AUTHORS   Schmidt,M.R., Maritzen,T., Kukhtina,V., Higman,V.A., Doglio,L.,
            Barak,N.N., Strauss,H., Oschkinat,H., Dotti,C.G. and Haucke,V.
  TITLE     Regulation of endosomal membrane traffic by a Gadkin/AP-1/kinesin
            KIF5 complex
  JOURNAL   Proc Natl Acad Sci U S A 106 (36), 15344-15349 (2009)
   PUBMED   19706427
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Jul 17, 2010 this sequence version replaced XM_342338.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760393, SAMEA5760400
                              [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-77                JAXUCZ010000002.1  218983138-218983214 c
            78-83               JAXUCZ010000002.1  218970622-218970627 c
            84-132              JAXUCZ010000002.1  218967050-218967098 c
            133-159             JAXUCZ010000002.1  218966232-218966258 c
            160-185             JAXUCZ010000002.1  218964489-218964514 c
            186-282             JAXUCZ010000002.1  218960487-218960583 c
            283-381             JAXUCZ010000002.1  218959028-218959126 c
            382-437             JAXUCZ010000002.1  218957003-218957058 c
            438-511             JAXUCZ010000002.1  218956302-218956375 c
            512-640             JAXUCZ010000002.1  218955986-218956114 c
            641-2374            JAXUCZ010000002.1  218951104-218952837 c
FEATURES             Location/Qualifiers
     source          1..2374
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q42"
     gene            1..2374
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /note="adaptor-related protein complex 1 associated
                     regulatory protein"
                     /db_xref="GeneID:362037"
                     /db_xref="RGD:1311435"
     CDS             1..903
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /codon_start=1
                     /product="AP-1 complex-associated regulatory protein"
                     /protein_id="NP_001178779.1"
                     /db_xref="GeneID:362037"
                     /db_xref="RGD:1311435"
                     /translation="MGNCCWTQCFGLLRREAGRLQRAGGGGGSKYFRTCPRGEHLTIE
                     FENLVESDEGESPGSSHRPLTEEEIVDLQERHYDSIAEKQKDVDRKIQRELALQEEKL
                     RLEEEALYAAQREAARAARQRKLLEQEKQRIAQRYHPSSGDCQSVGPEDDFEASLRNI
                     KSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRM
                     LPMRERSKTEEDILRAALKCSSKKGSNPTSASDDSNGLEWENDFVSAEMDDNGNSEYA
                     GFVNPVLELSESAIKQSDTDQQIR"
     exon            1..77
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /inference="alignment:Splign:2.1.0"
     exon            78..83
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /inference="alignment:Splign:2.1.0"
     exon            84..132
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /inference="alignment:Splign:2.1.0"
     exon            133..159
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /inference="alignment:Splign:2.1.0"
     exon            160..185
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /inference="alignment:Splign:2.1.0"
     exon            186..282
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /inference="alignment:Splign:2.1.0"
     exon            283..381
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /inference="alignment:Splign:2.1.0"
     exon            382..437
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /inference="alignment:Splign:2.1.0"
     exon            438..511
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /inference="alignment:Splign:2.1.0"
     exon            512..640
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /inference="alignment:Splign:2.1.0"
     exon            641..2374
                     /gene="Ap1ar"
                     /gene_synonym="RGD1311435"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggggaact gctgctggac gcaatgcttc gggctgctcc gccgggaagc gggtcggctg
       61 cagcgagcgg gcggaggtgg aggatccaag tattttagaa catgcccaag aggagagcac
      121 ttgaccatag agtttgagaa tcttgtggag agcgatgagg gggagagccc aggaagcagc
      181 cataggccac ttactgagga agaaatcgtt gacttacaag agaggcatta tgactctatt
      241 gctgagaagc agaaagacgt ggataggaaa atccagaggg agttagcctt acaagaggag
      301 aagttaagac tagaagaaga agctttatac gctgcccagc gtgaagcagc cagggcagca
      361 aggcagcgaa agctcctgga gcaagaaaag cagagaattg cccagcgcta tcatcccagc
      421 agtggagact gtcaaagtgt aggaccagaa gacgactttg aagcttcctt aagaaatata
      481 aagtcacagt atgaagtttt tcgaagtagt agactctcat ctgatgccac agtgttgaca
      541 ccaaatacgg aaagcagctg tgacctaatg accaaaacca aatcaaccag tgggaatgac
      601 gacagcacct ccttagacct ggagtgggaa gatgaagaag gaatgaatag gatgctgccc
      661 atgagagagc gctccaagac agaggaagac atcctgcggg cagcgctgaa gtgcagcagc
      721 aagaagggca gcaaccccac gtccgcctcc gatgactcca acgggctgga gtgggagaac
      781 gactttgtca gtgccgagat ggacgacaat ggcaattctg agtacgcggg gtttgtgaat
      841 cctgtgttgg aactgtcgga gtccgccatc aagcagtctg atacagatca gcagatccgg
      901 tagggtgaag ctgtgacctt actcaccaaa tgttaacaat cagctagaat gtacaggtgg
      961 cacgccaggg ctctttgtga gggcagcaaa ataccacgtg acagatgctt gttttcctgg
     1021 agggacagct gagtgctcca gttggtgtga gcgcagcatc tgccttctgc gtcccaggac
     1081 tgactcagtg attctgacat atcaaacact catgcctttc tgttcacccc gtcaagttct
     1141 gcatcttaag tctgcattcg ttttcctctg accgctttac tcagcctatc ttcctataac
     1201 aatctaaaag tgtttttgtt agttcagcat atgtacaggc agcatgagga ggtgggggga
     1261 tcccaggaag gcagaccctt ccagcagagg ctcctttggt tgcttttact cttcttgtct
     1321 tgtagacagc aggaattgga gatgacccaa gcatactgat gtgcgggcac acacgcgcac
     1381 acacacacac acgcacacac acacacacac acacacacac acacacacat cctaagccct
     1441 gcttcactca atctggtgac aggattaaag atgcttccag agtttggaca ctttgagttg
     1501 gtaataatga aaactaatac ataaaaatat atatttaaaa tttttacttc ctttcacatg
     1561 ccattatatt ggctttaaat tgagatttta agttttcact ttcatttttt aaaaattcta
     1621 tatttccagt gagtgatctt tgaaagattt ttacacagaa catattctgt gagtgattta
     1681 agaagacatt aaaatacggg tatttcaaag tatataacct cctttctgat atgaaaggtc
     1741 ccattgtatt accctttcct tcgccttgta gtgcaaggcg ctgtgtggga tggaactaaa
     1801 atggcggcgt attaaagacc catgtctgaa tctgtagaga aggccagggc tgggaagtgt
     1861 ttcctaactg cgttccttgc tttggctgag gactgagtgt cactttggga agcacacggc
     1921 attctgtctc ccttgctgtt ttcctctcct cagcagcgat ggtgcatgct ttcagcagta
     1981 cagggcggtc aggtagaaat agtcaagttc ttgctgtgcg tgaaaactta tgtggccctt
     2041 tcaatatttg aactgctata cgatgacatc tataattttg tcatttttaa atctcataca
     2101 aataaatata ctttgatatg taaatatgca ttaggttatg ctattattta tatctatctt
     2161 aagatttaaa ttgtaggtgt gtcatggaaa taatttaaag gcactctgtt cacattgcct
     2221 gtgttcatgc tttctaaggt ttatattaca tcagatgtat atttttggtt tggcataagc
     2281 tactgttgta attttcttgg ctttttgttc ataaagaatt ttctgaagga atggtaacct
     2341 ttcaaggatt gtgaataaac atttttacaa ttaa
//
