LOCUS       XM_008771432            6218 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus aminopeptidase O (Aopep), transcript
            variant X7, mRNA.
ACCESSION   XM_008771432
VERSION     XM_008771432.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051352.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008771432.4.
            
            On Jan 21, 2021 this sequence version replaced XM_008771432.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6218
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6218
                     /gene="Aopep"
                     /gene_synonym="Apo; Npepo; RGD1309592"
                     /note="aminopeptidase O; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 5
                     mRNAs, 44 ESTs, 5 long SRA reads, 9 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 49 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:290963"
                     /db_xref="RGD:1309592"
     CDS             267..2735
                     /gene="Aopep"
                     /gene_synonym="Apo; Npepo; RGD1309592"
                     /codon_start=1
                     /product="aminopeptidase O isoform X2"
                     /protein_id="XP_008769654.1"
                     /db_xref="GeneID:290963"
                     /db_xref="RGD:1309592"
                     /translation="MDINLDPSRDDLPLMANTSHLLVKHYVLDLDVDFGSRVLEGNIV
                     LFFGDGNRCKKQSSSSQETFQMESEEAYILRTAEPCHVPKMDSNTFSPKMGHREFAVF
                     GKSDQDAFDNDGNHDNKEHDSESSSSKYCCDTGNHGREDFLLVLDCCDLSVLKVEEVD
                     VAAVPDLEKFTKAPNLTAAPEKRRCEIVRDLVALPADAWREQLDCYTRCSQAPGCGEL
                     LFDSDKWSLQIRKKGVPTAADFPHAIRIWYKTKPEGQSVTWTSDQDGRPCVYTMGSPI
                     NNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGEKSAKPTPLREGYMSWHYYVTMPM
                     PASTFTIAVGCWTEMKPKTSPLDDLTEHTLPLRPSDADFRYGNTCSHMEYPCRFQSAS
                     AATQNIIPYRVFAPVCLEGACREALLWLIPSCLSAAHSVLGTHPFSRLDILIVPTNFP
                     SLGMASPHIIFLSQSTLTGTSHLCGTRLCHEIAHAWFGLAIGARDWTEEWLSEGFATH
                     LEDIFWAEAQQLPPHEALEQQELRACLRWHRLQDELQNSPEGMQVLRPNKEKTGHVSA
                     SGASVVKNGLNPEKGFMQVHYLKGYFLLRFLARTLGEETYFPFLRKFVHLFHGQLILS
                     QDFLQMLLESIPENKRFGLSVENIVGDWLECPGIPKALQEERKAKDCSPSRLVRQVGS
                     EVAKWIRVNRRPGKRQRRKREAAFEKLSPDQIVLLLEWLLEQKTLSPQTLHRLQQTYH
                     LQEQDAEVRHRWCELVIKHKYTKAYDQVKRFLQEDQAMGIYLYGELMVSEDARLQQLA
                     HRCFELVKGHMDKASAQVVTEMLF"
ORIGIN      
        1 cctggtagcc cgtggtaacc cggagtctgc ggaagtgtag ctgcagcacg gtggccgaca
       61 ggtaacccgc agctcggctg tcaaccagcc actccgggtt atggggatcg gcgacctctg
      121 atgagggaat tggaagttgt ggaaagacaa cctatgccag tgggtgcttc ttatttggta
      181 agccagccat ttgtgattct gagctgctag aggagataag aagcctcagc tgcgattcag
      241 caaagctacc aactgcaaac tacaccatgg acataaacct ggacccttct cgggatgatc
      301 tgcctctcat ggccaacacc agccacctgc ttgtgaagca ctacgtactg gatttggatg
      361 tggactttgg aagtcgagtc cttgagggca acatagtgct tttctttgga gatggaaaca
      421 gatgtaaaaa acaatcgagt tcctcccagg aaaccttcca gatggagtca gaggaagcct
      481 acatacttag gacagctgaa ccctgccatg ttccaaagat ggattcaaat actttctcac
      541 ctaagatggg acatagagaa tttgcagtct ttggtaaaag tgatcaagat gcctttgata
      601 atgatggtaa ccatgacaac aaggaacatg attctgagag ctctagctca aagtactgct
      661 gtgacacagg gaatcatggg agagaggatt tcttgctagt gttggactgc tgtgatttgt
      721 ctgtgctaaa ggtagaggag gtggatgtag ctgctgtgcc agatcttgag aaatttacaa
      781 aagctccaaa cctcacagct gctcctgaga agcgcaggtg tgagattgtc cgtgaccttg
      841 tggctctgcc tgcagatgct tggagggagc agttagactg ctacactcgc tgcagccagg
      901 ctcctggctg tggggagctc ttgtttgact ctgacaagtg gagcttacag atcaggaaga
      961 agggggttcc gacagctgct gactttcctc atgccatcag gatatggtat aaaactaaac
     1021 ctgaggggca gtcagtgact tggacctcag accaggatgg caggccatgt gtttatacta
     1081 tgggatcccc catcaacaac agggcccttt ttccatgcca ggaaccaccg gttgccatgt
     1141 caacatggca ggctacagtt cgagcagctg catcttttgt tgttttaatg agtggggaaa
     1201 agtctgccaa gcccacacca cttcgagaag gatacatgag ctggcattac tatgtgacca
     1261 tgccaatgcc tgcctctacc ttcacaattg cagtgggatg ctggacagaa atgaagccca
     1321 agacatcccc attagatgat ctgactgagc acaccctccc cctccgacca tcagacgctg
     1381 acttcaggta tggtaacacc tgcagtcata tggaataccc ctgccggttc cagagtgcgt
     1441 ctgctgccac ccagaacatc attccttatc gagtgtttgc cccagtgtgc cttgagggtg
     1501 cctgccgaga ggccctgctg tggctgatcc cctcttgcct ctcagctgca cactctgtcc
     1561 tgggaacaca ccctttctcc aggctggaca tacttattgt ccccaccaac ttcccaagtc
     1621 tgggaatggc cagcccacac atcatcttcc tctctcagag caccttgaca ggcacaagcc
     1681 atctctgcgg gacccgtctt tgccatgaaa ttgctcatgc ctggtttggc ctagccatag
     1741 gggcccgaga ctggacagag gagtggctca gcgaaggatt tgccactcac ttggaagata
     1801 tattttgggc tgaagcacag cagctgcccc cacatgaggc cctggagcag caagagctga
     1861 gggcttgcct gcgctggcac cgcctgcagg atgagcttca gaactcccca gagggaatgc
     1921 aggtgttaag acccaacaaa gagaagactg gtcacgtgag tgcttcaggt gcctctgttg
     1981 tcaagaatgg actcaaccca gagaagggct tcatgcaggt tcattactta aagggctact
     2041 tccttcttcg attcctagcc agaacacttg gagaggaaac ttattttcca tttttaagaa
     2101 aatttgtgca cctgtttcat gggcagttga ttctttccca ggattttctt caaatgctgt
     2161 tggagagcat tccagaaaac aaaaggttcg gcctgtctgt tgagaacatc gtcggtgatt
     2221 ggcttgagtg tcccggaata cccaaggcac tgcaggagga gcgcaaggcc aaggactgct
     2281 cgccgagtag gctggtacgg caagtgggct ccgaggtggc caaatggatt cgagtgaacc
     2341 gaagacccgg aaaacgccaa cgaaggaaac gtgaagccgc ctttgaaaag ctttctccag
     2401 accagatcgt gttgcttttg gagtggctct tagagcagaa gaccctgagc ccccagacat
     2461 tgcatcgtct ccagcagacg taccatctcc aggagcagga tgcagaggtt cgccatcgat
     2521 ggtgtgaact ggttattaag cacaagtaca caaaggcata tgatcaggtc aagaggttcc
     2581 tacaggagga tcaggccatg ggcatatacc tctacgggga gctgatggtg agtgaggatg
     2641 ccaggctgca gcagcttgcc caccggtgct ttgagctggt aaagggacac atggacaaag
     2701 catccgccca ggtggtgacc gaaatgctgt tctaaagagg taattttctt tctttctcct
     2761 cctaaccctc catgttgatt tgaaagccac agatgagcca aggccgccac agcaccagag
     2821 ggctgccaag cggtcttggg gagcaagcag ggtgggtccc caagaacagg aaggctcagg
     2881 atctctggag ccacctcgtc ttctggatat actggtgtaa aacaggttcc tactaaagga
     2941 ggaacagccc cctggtacct tggattctgc acagatccac aggcttctca gggtcaaggt
     3001 cagcacagtg gtccgcagcc tcgctgctcc aagcttcggc ctgcaggcgt ttctcctaga
     3061 ggctgtgtaa acctgagact ccttggcctc ttgtctcccc gacctgtaaa gtaggcagca
     3121 gcgtgttctt acacatcccc cttgctcagt gaccggtgag gtagacagca ggtcttcttt
     3181 gcctgtccac ccaggtgaca ctggcatcct aagggcaagt ctgtttccat ctggtgctgg
     3241 aacagggttt accctggctc ccagagtcct tgcctgtgct gttaccttcc ccctctagcc
     3301 aacttgttga ccagtagtgt agttgagcca caaagcatgg agttctggga cacaagtgtg
     3361 ggttagtgtg tttctttcac agtcatgtca tctctgcatc ttctttctca gttattgtca
     3421 tggtggtaca tatgatgttt acttttcgta tattttttaa attttacatc aatcactgtg
     3481 ttactgttgt tctctgtgag tactattatg aatgtttaga attgtgttgc taatcttaac
     3541 tcttggtcag gcattaaatt tacattttca catttcactt ttacaaaacc cactcctgtg
     3601 tactatgttt attttgttta tgtgaaagaa ctaatcttat gaaggggaag catgtttact
     3661 gaaatatgat ggtgttcttg cggaaatgct ggggaccgcc atagttgagc agaggagagt
     3721 gtggggtgga gtaagcctgc acaccacgac ctaggacggt ggcctgtgca agcaggcagg
     3781 ttcggctggg ctcctctcca ctgcctgctg caggcatttc tctaggaact tgtaagctca
     3841 gggattgttg gtgtggtgtg taaggtcaca ataaagccac tattctgtct tccggtcctt
     3901 tggccttcac tttggagagc cagagtcaga tagtggtacg agcgactctt ctaagggtat
     3961 ttttggcccc tgtgcaagca aatcctcaac ttccaagctc ccctgagaac tctatgctgt
     4021 accccagctc atccaaccaa atgcttggtc acagcagctc cagaaactct ctgcacacca
     4081 tgcctactga gaagagtttc ctatccaagg ggcccataga catctcaggc cattaaaaat
     4141 ctgcagtttg agaacagggt gtgtccccag ggttaaaggt cacatactca gagcgaggat
     4201 tggtcatgta gctgataagt gtgtcctttg tctcctggtt ccctatgctc ctctatacag
     4261 tgcagctagc atgctggatg acagcaggct acatacactg ctagcgtggt gggctcagag
     4321 gcggtgtgga ggacactcag cgcatgtgga tgggagtggt tgggcatggc gctgccctca
     4381 cctgctctgg ctgcttgggt tcctggcatg ctgatttgtg acttgagatt aaaatcacat
     4441 tgccagggat taccacgcaa ccatgacctt ggctgctcct gcagaaccgt ggctactttc
     4501 tctctgcagt ttggagaaca gaggcacctt gtggctcttt gggaaaaaaa aaaaaaaaaa
     4561 aagaagccac cagccttcga agatgctcac cagcccttta attatggccg gcgatgacct
     4621 ctctaacaag gtgcagagct tagctgattg gtgaacagtg attggtttcc gctttgttca
     4681 cagtggctaa gttctgcacc tgaagagaag gtgagatggg gacagttaac ttgcagctgc
     4741 caggcagagg ccactgcctg gtggtcactc cagaggagga gagaccagcc tgcctcaagg
     4801 ctgtgttgtc aagagtgcaa gcagcgtgct gaccaccctt aaatgtgcct acagaaaata
     4861 cagatctact gctaattagt ccactgtaat atcaagtgta ttggagtcac agaaaactaa
     4921 aaccagatgc atcacaaaag ctgagcggag tctcagctga tgccacacgt gagggtgggg
     4981 ttgggggtgg ttcttttgtc cctgctgggc gtggtgaact ctttcttgta tttgcagtcc
     5041 aggtctccat gtcttcacag tcgctggcag gatgatgccc agggcacgcc aggaggcact
     5101 gcccagctgt gattggaccc gccctccggt gcctactgag ctgatatcag ttctcatttc
     5161 acacactggc tcagttcagc aggaacagga gtcgagccct tgagcaaaaa gcctacccat
     5221 ctgtaagtgc ctgaggcagg cctcccacgg acaagaagat gaagggcctt gagtgtctgg
     5281 taccagaccc aacagcagtg gtatccctct gtatgtgctc ttgaggtggg gatttataga
     5341 gtgcagatca aactttggaa agattgcatt ccctagaagt aaggcagagc agaagccgag
     5401 cgtttgccat gtgtttgaga cagagcacac cctgttgtct gctgccttga gcagtgtgaa
     5461 tgctgtctta agggctttct gtagagccgc cttccattga atctctctgg gcttcacagc
     5521 cctgcatggc ctatgctgtg actgtgcacc ccaggtcgag gattgtgagg cgtggcttca
     5581 gtcttgtccc tgtcctccct gaaagttccc tctcaagtgg aggtcagagg ctaggagaac
     5641 tcctgtcaga atgactgtgg tgactgggta ataaatttta ttgctgtttc cttcacagga
     5701 cagatcacag tgagattctc tttcatacac cttctcctag ccctggtggg gccaggactg
     5761 cattgaccct ggacatcaaa gggaagatta tgtggctgct aaggccatca gcccacagca
     5821 gcggttggtc cagcttgggc ttctggctcc cagagcccgg gctcccgtgg catatataaa
     5881 aggcggagcc tcataaactg ttgcacctgg cagctgcctt tgtccccagt cctagagacc
     5941 gagtctacac actggaattg agctgtgact tgaaggcagt ccttcaaaag aatgaaggat
     6001 accctcccct aggcagatgg agaaccgact gcctgcttcc tgtgattgca agcactagct
     6061 gccatgctct gggactgcag aatcacatga cacctcctgt ggctggcccc caaggactct
     6121 gcagagaccc tttgatgtgt tcagtcaata gagcattcct gtttttgaaa atgcagggaa
     6181 gcctaagatg tcttaataaa gtaccggatt tgctggtg
//
