LOCUS       XM_008771429            6369 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus aminopeptidase O (Aopep), transcript
            variant X1, mRNA.
ACCESSION   XM_008771429
VERSION     XM_008771429.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051352.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008771429.4.
            
            On Jan 21, 2021 this sequence version replaced XM_008771429.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6369
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6369
                     /gene="Aopep"
                     /gene_synonym="Apo; Npepo; RGD1309592"
                     /note="aminopeptidase O; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 5
                     mRNAs, 44 ESTs, 5 long SRA reads, 9 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 7 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:290963"
                     /db_xref="RGD:1309592"
     CDS             226..2886
                     /gene="Aopep"
                     /gene_synonym="Apo; Npepo; RGD1309592"
                     /codon_start=1
                     /product="aminopeptidase O isoform X1"
                     /protein_id="XP_008769651.1"
                     /db_xref="GeneID:290963"
                     /db_xref="RGD:1309592"
                     /translation="MYGSGLKLTQSLLPLVQGIGSCGKTTYASGCFLFGKPAICDSEL
                     LEEIRSLSCDSAKLPTANYTMDINLDPSRDDLPLMANTSHLLVKHYVLDLDVDFGSRV
                     LEGNIVLFFGDGNRCKKQSSSSQETFQMESEEAYILRTAEPCHVPKMDSNTFSPKMGH
                     REFAVFGKSDQDAFDNDGNHDNKEHDSESSSSKYCCDTGNHGREDFLLVLDCCDLSVL
                     KVEEVDVAAVPDLEKFTKAPNLTAAPEKRRCEIVRDLVALPADAWREQLDCYTRCSQA
                     PGCGELLFDSDKWSLQIRKKGVPTAADFPHAIRIWYKTKPEGQSVTWTSDQDGRPCVY
                     TMGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGEKSAKPTPLREGYMSWHY
                     YVTMPMPASTFTIAVGCWTEMKPKTSPLDDLTEHTLPLRPSDADFRYGNTCSHMEYPC
                     RFQSASAATQNIIPYRVFAPVCLEGACREALLWLIPSCLSAAHSVLGTHPFSRLDILI
                     VPTNFPSLGMASPHIIFLSQSTLTGTSHLCGTRLCHEIAHAWFGLAIGARDWTEEWLS
                     EGFATHLEDIFWAEAQQLPPHEALEQQELRACLRWHRLQDELQNSPEGMQVLRPNKEK
                     TGHVSASGASVVKNGLNPEKGFMQVHYLKGYFLLRFLARTLGEETYFPFLRKFVHLFH
                     GQLILSQDFLQMLLESIPENKRFGLSVENIVGDWLECPGIPKALQEERKAKDCSPSRL
                     VRQVGSEVAKWIRVNRRPGKRQRRKREAAFEKLSPDQIVLLLEWLLEQKTLSPQTLHR
                     LQQTYHLQEQDAEVRHRWCELVIKHKYTKAYDQVKRFLQEDQAMGIYLYGELMVSEDA
                     RLQQLAHRCFELVKGHMDKASAQVVTEMLF"
ORIGIN      
        1 cgtggtaacc cggagtctgc ggaagtgtag ctgcagcacg gtggccgaca ggtaacccgc
       61 agctcggctg tcaaccagcc actccgggtt atggggatcg gcgacctctg atgaggtgag
      121 cagggagcag aggaagtacc gagtggatgt attctgttga catggacaca gacatgacaa
      181 ggaccttcag aactatgaga actgacaaaa cctttcaccg tatatatgta tgggtcaggg
      241 ttaaagttga cacagagcct tcttcctctg gtacaaggaa ttggaagttg tggaaagaca
      301 acctatgcca gtgggtgctt cttatttggt aagccagcca tttgtgattc tgagctgcta
      361 gaggagataa gaagcctcag ctgcgattca gcaaagctac caactgcaaa ctacaccatg
      421 gacataaacc tggacccttc tcgggatgat ctgcctctca tggccaacac cagccacctg
      481 cttgtgaagc actacgtact ggatttggat gtggactttg gaagtcgagt ccttgagggc
      541 aacatagtgc ttttctttgg agatggaaac agatgtaaaa aacaatcgag ttcctcccag
      601 gaaaccttcc agatggagtc agaggaagcc tacatactta ggacagctga accctgccat
      661 gttccaaaga tggattcaaa tactttctca cctaagatgg gacatagaga atttgcagtc
      721 tttggtaaaa gtgatcaaga tgcctttgat aatgatggta accatgacaa caaggaacat
      781 gattctgaga gctctagctc aaagtactgc tgtgacacag ggaatcatgg gagagaggat
      841 ttcttgctag tgttggactg ctgtgatttg tctgtgctaa aggtagagga ggtggatgta
      901 gctgctgtgc cagatcttga gaaatttaca aaagctccaa acctcacagc tgctcctgag
      961 aagcgcaggt gtgagattgt ccgtgacctt gtggctctgc ctgcagatgc ttggagggag
     1021 cagttagact gctacactcg ctgcagccag gctcctggct gtggggagct cttgtttgac
     1081 tctgacaagt ggagcttaca gatcaggaag aagggggttc cgacagctgc tgactttcct
     1141 catgccatca ggatatggta taaaactaaa cctgaggggc agtcagtgac ttggacctca
     1201 gaccaggatg gcaggccatg tgtttatact atgggatccc ccatcaacaa cagggccctt
     1261 tttccatgcc aggaaccacc ggttgccatg tcaacatggc aggctacagt tcgagcagct
     1321 gcatcttttg ttgttttaat gagtggggaa aagtctgcca agcccacacc acttcgagaa
     1381 ggatacatga gctggcatta ctatgtgacc atgccaatgc ctgcctctac cttcacaatt
     1441 gcagtgggat gctggacaga aatgaagccc aagacatccc cattagatga tctgactgag
     1501 cacaccctcc ccctccgacc atcagacgct gacttcaggt atggtaacac ctgcagtcat
     1561 atggaatacc cctgccggtt ccagagtgcg tctgctgcca cccagaacat cattccttat
     1621 cgagtgtttg ccccagtgtg ccttgagggt gcctgccgag aggccctgct gtggctgatc
     1681 ccctcttgcc tctcagctgc acactctgtc ctgggaacac accctttctc caggctggac
     1741 atacttattg tccccaccaa cttcccaagt ctgggaatgg ccagcccaca catcatcttc
     1801 ctctctcaga gcaccttgac aggcacaagc catctctgcg ggacccgtct ttgccatgaa
     1861 attgctcatg cctggtttgg cctagccata ggggcccgag actggacaga ggagtggctc
     1921 agcgaaggat ttgccactca cttggaagat atattttggg ctgaagcaca gcagctgccc
     1981 ccacatgagg ccctggagca gcaagagctg agggcttgcc tgcgctggca ccgcctgcag
     2041 gatgagcttc agaactcccc agagggaatg caggtgttaa gacccaacaa agagaagact
     2101 ggtcacgtga gtgcttcagg tgcctctgtt gtcaagaatg gactcaaccc agagaagggc
     2161 ttcatgcagg ttcattactt aaagggctac ttccttcttc gattcctagc cagaacactt
     2221 ggagaggaaa cttattttcc atttttaaga aaatttgtgc acctgtttca tgggcagttg
     2281 attctttccc aggattttct tcaaatgctg ttggagagca ttccagaaaa caaaaggttc
     2341 ggcctgtctg ttgagaacat cgtcggtgat tggcttgagt gtcccggaat acccaaggca
     2401 ctgcaggagg agcgcaaggc caaggactgc tcgccgagta ggctggtacg gcaagtgggc
     2461 tccgaggtgg ccaaatggat tcgagtgaac cgaagacccg gaaaacgcca acgaaggaaa
     2521 cgtgaagccg cctttgaaaa gctttctcca gaccagatcg tgttgctttt ggagtggctc
     2581 ttagagcaga agaccctgag cccccagaca ttgcatcgtc tccagcagac gtaccatctc
     2641 caggagcagg atgcagaggt tcgccatcga tggtgtgaac tggttattaa gcacaagtac
     2701 acaaaggcat atgatcaggt caagaggttc ctacaggagg atcaggccat gggcatatac
     2761 ctctacgggg agctgatggt gagtgaggat gccaggctgc agcagcttgc ccaccggtgc
     2821 tttgagctgg taaagggaca catggacaaa gcatccgccc aggtggtgac cgaaatgctg
     2881 ttctaaagag gtaattttct ttctttctcc tcctaaccct ccatgttgat ttgaaagcca
     2941 cagatgagcc aaggccgcca cagcaccaga gggctgccaa gcggtcttgg ggagcaagca
     3001 gggtgggtcc ccaagaacag gaaggctcag gatctctgga gccacctcgt cttctggata
     3061 tactggtgta aaacaggttc ctactaaagg aggaacagcc ccctggtacc ttggattctg
     3121 cacagatcca caggcttctc agggtcaagg tcagcacagt ggtccgcagc ctcgctgctc
     3181 caagcttcgg cctgcaggcg tttctcctag aggctgtgta aacctgagac tccttggcct
     3241 cttgtctccc cgacctgtaa agtaggcagc agcgtgttct tacacatccc ccttgctcag
     3301 tgaccggtga ggtagacagc aggtcttctt tgcctgtcca cccaggtgac actggcatcc
     3361 taagggcaag tctgtttcca tctggtgctg gaacagggtt taccctggct cccagagtcc
     3421 ttgcctgtgc tgttaccttc cccctctagc caacttgttg accagtagtg tagttgagcc
     3481 acaaagcatg gagttctggg acacaagtgt gggttagtgt gtttctttca cagtcatgtc
     3541 atctctgcat cttctttctc agttattgtc atggtggtac atatgatgtt tacttttcgt
     3601 atatttttta aattttacat caatcactgt gttactgttg ttctctgtga gtactattat
     3661 gaatgtttag aattgtgttg ctaatcttaa ctcttggtca ggcattaaat ttacattttc
     3721 acatttcact tttacaaaac ccactcctgt gtactatgtt tattttgttt atgtgaaaga
     3781 actaatctta tgaaggggaa gcatgtttac tgaaatatga tggtgttctt gcggaaatgc
     3841 tggggaccgc catagttgag cagaggagag tgtggggtgg agtaagcctg cacaccacga
     3901 cctaggacgg tggcctgtgc aagcaggcag gttcggctgg gctcctctcc actgcctgct
     3961 gcaggcattt ctctaggaac ttgtaagctc agggattgtt ggtgtggtgt gtaaggtcac
     4021 aataaagcca ctattctgtc ttccggtcct ttggccttca ctttggagag ccagagtcag
     4081 atagtggtac gagcgactct tctaagggta tttttggccc ctgtgcaagc aaatcctcaa
     4141 cttccaagct cccctgagaa ctctatgctg taccccagct catccaacca aatgcttggt
     4201 cacagcagct ccagaaactc tctgcacacc atgcctactg agaagagttt cctatccaag
     4261 gggcccatag acatctcagg ccattaaaaa tctgcagttt gagaacaggg tgtgtcccca
     4321 gggttaaagg tcacatactc agagcgagga ttggtcatgt agctgataag tgtgtccttt
     4381 gtctcctggt tccctatgct cctctataca gtgcagctag catgctggat gacagcaggc
     4441 tacatacact gctagcgtgg tgggctcaga ggcggtgtgg aggacactca gcgcatgtgg
     4501 atgggagtgg ttgggcatgg cgctgccctc acctgctctg gctgcttggg ttcctggcat
     4561 gctgatttgt gacttgagat taaaatcaca ttgccaggga ttaccacgca accatgacct
     4621 tggctgctcc tgcagaaccg tggctacttt ctctctgcag tttggagaac agaggcacct
     4681 tgtggctctt tgggaaaaaa aaaaaaaaaa aaagaagcca ccagccttcg aagatgctca
     4741 ccagcccttt aattatggcc ggcgatgacc tctctaacaa ggtgcagagc ttagctgatt
     4801 ggtgaacagt gattggtttc cgctttgttc acagtggcta agttctgcac ctgaagagaa
     4861 ggtgagatgg ggacagttaa cttgcagctg ccaggcagag gccactgcct ggtggtcact
     4921 ccagaggagg agagaccagc ctgcctcaag gctgtgttgt caagagtgca agcagcgtgc
     4981 tgaccaccct taaatgtgcc tacagaaaat acagatctac tgctaattag tccactgtaa
     5041 tatcaagtgt attggagtca cagaaaacta aaaccagatg catcacaaaa gctgagcgga
     5101 gtctcagctg atgccacacg tgagggtggg gttgggggtg gttcttttgt ccctgctggg
     5161 cgtggtgaac tctttcttgt atttgcagtc caggtctcca tgtcttcaca gtcgctggca
     5221 ggatgatgcc cagggcacgc caggaggcac tgcccagctg tgattggacc cgccctccgg
     5281 tgcctactga gctgatatca gttctcattt cacacactgg ctcagttcag caggaacagg
     5341 agtcgagccc ttgagcaaaa agcctaccca tctgtaagtg cctgaggcag gcctcccacg
     5401 gacaagaaga tgaagggcct tgagtgtctg gtaccagacc caacagcagt ggtatccctc
     5461 tgtatgtgct cttgaggtgg ggatttatag agtgcagatc aaactttgga aagattgcat
     5521 tccctagaag taaggcagag cagaagccga gcgtttgcca tgtgtttgag acagagcaca
     5581 ccctgttgtc tgctgccttg agcagtgtga atgctgtctt aagggctttc tgtagagccg
     5641 ccttccattg aatctctctg ggcttcacag ccctgcatgg cctatgctgt gactgtgcac
     5701 cccaggtcga ggattgtgag gcgtggcttc agtcttgtcc ctgtcctccc tgaaagttcc
     5761 ctctcaagtg gaggtcagag gctaggagaa ctcctgtcag aatgactgtg gtgactgggt
     5821 aataaatttt attgctgttt ccttcacagg acagatcaca gtgagattct ctttcataca
     5881 ccttctccta gccctggtgg ggccaggact gcattgaccc tggacatcaa agggaagatt
     5941 atgtggctgc taaggccatc agcccacagc agcggttggt ccagcttggg cttctggctc
     6001 ccagagcccg ggctcccgtg gcatatataa aaggcggagc ctcataaact gttgcacctg
     6061 gcagctgcct ttgtccccag tcctagagac cgagtctaca cactggaatt gagctgtgac
     6121 ttgaaggcag tccttcaaaa gaatgaagga taccctcccc taggcagatg gagaaccgac
     6181 tgcctgcttc ctgtgattgc aagcactagc tgccatgctc tgggactgca gaatcacatg
     6241 acacctcctg tggctggccc ccaaggactc tgcagagacc ctttgatgtg ttcagtcaat
     6301 agagcattcc tgtttttgaa aatgcaggga agcctaagat gtcttaataa agtaccggat
     6361 ttgctggtg
//
