LOCUS       NM_001398916            3935 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus ANTXR cell adhesion molecule 2 (Antxr2), mRNA.
ACCESSION   NM_001398916 XM_039092656
VERSION     NM_001398916.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3935)
  AUTHORS   Liu,Y., Xie,C., Li,T., Lu,C., Fan,L., Zhang,Z., Peng,S., Lv,N. and
            Lu,D.
  TITLE     PCGEM1 promotes cell proliferation and migration in endometriosis
            by targeting miR-124-3p-mediated ANTXR2 expression
  JOURNAL   BMC Womens Health 23 (1), 104 (2023)
   PUBMED   36915057
  REMARK    GeneRIF: PCGEM1 promotes cell proliferation and migration in
            endometriosis by targeting miR-124-3p-mediated ANTXR2 expression.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3935)
  AUTHORS   Liu,X., Yuan,W., Li,J., Yang,L. and Cai,J.
  TITLE     ANTXR2 Knock-Out Does Not Result in the Development of Hypertension
            in Rats
  JOURNAL   Am J Hypertens 30 (2), 182-187 (2017)
   PUBMED   28077422
  REMARK    GeneRIF: ANTXR2 might not be associated with hypertension and thus
            further functional analysis is warranted to identify the causal
            gene at this locus.
REFERENCE   3  (bases 1 to 3935)
  AUTHORS   Slater,L.H., Hett,E.C., Clatworthy,A.E., Mark,K.G. and Hung,D.T.
  TITLE     CCT chaperonin complex is required for efficient delivery of
            anthrax toxin into the cytosol of host cells
  JOURNAL   Proc Natl Acad Sci U S A 110 (24), 9932-9937 (2013)
   PUBMED   23716698
REFERENCE   4  (bases 1 to 3935)
  AUTHORS   Liu,S., Crown,D., Miller-Randolph,S., Moayeri,M., Wang,H., Hu,H.,
            Morley,T. and Leppla,S.H.
  TITLE     Capillary morphogenesis protein-2 is the major receptor mediating
            lethality of anthrax toxin in vivo
  JOURNAL   Proc Natl Acad Sci U S A 106 (30), 12424-12429 (2009)
   PUBMED   19617532
REFERENCE   5  (bases 1 to 3935)
  AUTHORS   Scobie,H.M., Wigelsworth,D.J., Marlett,J.M., Thomas,D.,
            Rainey,G.J., Lacy,D.B., Manchester,M., Collier,R.J. and Young,J.A.
  TITLE     Anthrax toxin receptor 2-dependent lethal toxin killing in vivo
  JOURNAL   PLoS Pathog 2 (10), e111 (2006)
   PUBMED   17054395
  REMARK    Erratum:[PLoS Pathog. 2008
            Oct;4(10).doi:10.1371/annotation/08c1bcf0-da65-4abd-97c7-
            5df86b1120b5]
REFERENCE   6  (bases 1 to 3935)
  AUTHORS   Hanks,S., Adams,S., Douglas,J., Arbour,L., Atherton,D.J., Balci,S.,
            Bode,H., Campbell,M.E., Feingold,M., Keser,G., Kleijer,W.,
            Mancini,G., McGrath,J.A., Muntoni,F., Nanda,A., Teare,M.D.,
            Warman,M., Pope,F.M., Superti-Furga,A., Futreal,P.A. and Rahman,N.
  TITLE     Mutations in the gene encoding capillary morphogenesis protein 2
            cause juvenile hyaline fibromatosis and infantile systemic
            hyalinosis
  JOURNAL   Am J Hum Genet 73 (4), 791-800 (2003)
   PUBMED   14508707
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On Dec 28, 2021 this sequence version replaced XM_039092656.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.53973.1,
                                           SRR26643297.42855.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-745               JAXUCZ010000014.1  11845774-11846518
            746-817             JAXUCZ010000014.1  11847221-11847292
            818-889             JAXUCZ010000014.1  11849599-11849670
            890-971             JAXUCZ010000014.1  11866329-11866410
            972-1079            JAXUCZ010000014.1  11866898-11867005
            1080-1148           JAXUCZ010000014.1  11867163-11867231
            1149-1229           JAXUCZ010000014.1  11868017-11868097
            1230-1290           JAXUCZ010000014.1  11885897-11885957
            1291-1389           JAXUCZ010000014.1  11888512-11888610
            1390-1459           JAXUCZ010000014.1  11891547-11891616
            1460-1538           JAXUCZ010000014.1  11901917-11901995
            1539-1634           JAXUCZ010000014.1  11906751-11906846
            1635-1676           JAXUCZ010000014.1  11918002-11918043
            1677-1772           JAXUCZ010000014.1  11918857-11918952
            1773-1937           JAXUCZ010000014.1  11929039-11929203
            1938-2018           JAXUCZ010000014.1  11929439-11929519
            2019-3935           JAXUCZ010000014.1  11984250-11986166
FEATURES             Location/Qualifiers
     source          1..3935
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..3935
                     /gene="Antxr2"
                     /note="ANTXR cell adhesion molecule 2"
                     /db_xref="GeneID:305633"
                     /db_xref="RGD:1561294"
     exon            1..745
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     CDS             594..2057
                     /gene="Antxr2"
                     /note="anthrax toxin receptor 2"
                     /codon_start=1
                     /product="anthrax toxin receptor 2 precursor"
                     /protein_id="NP_001385845.1"
                     /db_xref="GeneID:305633"
                     /db_xref="RGD:1561294"
                     /translation="MVAGRSRARSPGSWLFPGLWLLTVGGPGSLLQAQEQPSCKKAFD
                     LYFVLDKSGSVANNWIEIYNFVHQLTERFVSPEMRLSFIVFSSQATIILPLTGDRYKI
                     SKGLEDLKAVQPVGETYIHEGLKLANEQIQNAGGLKTSSIIIALTDGKLDGLVPSYAE
                     KEAKKSRSLGASVYCVGVLDFEQAQLERIADSKDQVFPVKGGFQALKGIINSILAQSC
                     TEILELSPSSVCVGETFQVVLSGRAVMSIRDDGSVLCTFTANSTYTKNEKPVSVQPGS
                     ILCPAPVLNKAGETLEVSIAFNDGKSAVSRSLTITATECSNGIAAIIAILVLLLLLGA
                     ALMWWFWPLCCKVVIKDPPPPPSPPKEEEEEEPLPNKKWPTVDASYYGGRGVGGIKRM
                     EVRWGDKGSTEEGARLEKAKNAVVMIPEEEIPVPSRPPRPKPTHQAPQTKWYTPIKGR
                     LDALWALILKQYDRVSLMRPQEGDEGRCINFSRVPHQ"
     exon            746..817
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            818..889
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            890..971
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1079
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1148
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1149..1229
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1290
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..1389
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1459
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1460..1538
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1634
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1676
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1677..1772
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1773..1937
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1938..2018
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
     exon            2019..3935
                     /gene="Antxr2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atccccagct gtagaagctc gccctgcggc acggcgccag gttccgggca gagaagaaag
       61 ttgtaaagtg ctgcgaggag ttgggcggtc tgaggaagag aggcggaaaa ggaggactcg
      121 gctgagtttc cctggcgatc gtggggtccg cgggcatctg tcccactgct catcacgcca
      181 gctagacgcc agcctctcta ctcccgggtg ggcgctggag actcggcggg aggctgcgag
      241 gaacttgtcc tgagagctgt cgccgcgggc ctcattgtct gcagcaactc tccggaaccc
      301 ggagtgggag gactggactc cgtccactgg gatttgccca gagttccggc ggcagctgtg
      361 gcggccgcgg agactctctt tgtcctccca ggacttcgct ctctctcctc ggtggcagct
      421 gttgggtggc tctgagcttg gagcgggcat cccagccccg ctcagcctct gaccctgggg
      481 tgagtcccca gtgactccgc ctctttctcg tcttagctct gagaagccca gtagcagacc
      541 ccggagcccg aggggttgtg agacgaaggg agcctctggt cccgggtcac aggatggtgg
      601 caggtcggtc ccgggcgcgg agccctggga gctggctgtt ccctggcctg tggctgttga
      661 ctgtgggcgg tccggggtcg ttgctgcaag cccaggaaca gccctcttgc aaaaaagcct
      721 tcgatttgta cttcgtcctg gacaagtctg ggagtgtagc aaataactgg attgaaattt
      781 acaattttgt ccaccaactg acagagagat ttgtgagtcc tgaaatgaga ttgtccttca
      841 ttgtgttttc ttcccaagca accatcattt tgccattaac tggagacaga tacaagatca
      901 gcaaaggact ggaggattta aaagctgttc agcccgtggg agagacatac atccatgagg
      961 ggctaaagct tgcgaacgaa caaattcaaa atgcaggagg cttgaaaacc tccagtatca
     1021 taatcgctct gactgacggg aaactggatg gcctggtacc atcatatgca gagaaagagg
     1081 caaagaagtc caggtcactt ggcgctagtg tttactgtgt tggggtcctt gattttgagc
     1141 aagctcagct ggaaagaatt gctgactcca aggaccaagt tttccccgtc aaaggcggtt
     1201 ttcaagctct taaagggatc atcaactcta tactagctca atcatgtacc gaaatcctgg
     1261 aattgagtcc ttcaagtgtc tgtgtagggg agacatttca agttgttctg agtggaagag
     1321 cagtcatgtc gatcagggat gacggcagtg tcctctgtac attcactgcg aacagcacat
     1381 acacaaagaa tgaaaaacca gtgagtgttc agcccggttc catcctctgt cctgcccctg
     1441 tcctgaacaa agctggagaa actcttgaag tttcaatcgc ctttaatgac gggaagtctg
     1501 ctgtctcaag atccttaaca atcacagcca cagaatgttc caacgggatt gcagccatca
     1561 tagctatttt ggtgttgttg ctgctcctgg gcgctgcctt gatgtggtgg ttttggcccc
     1621 tttgctgcaa agtggttatt aaggatcctc ccccaccacc ttctccacca aaggaggagg
     1681 aggaggaaga gcctttgccc aacaagaaat ggccaactgt ggatgcttcc tactatggcg
     1741 gtcgaggggt cggaggaatt aaaaggatgg aggtccgctg gggagataag ggttctacgg
     1801 aggaaggcgc aaggctagag aaagcaaaaa atgcggtggt gatgatccct gaagaagaga
     1861 tacctgtccc atcgagacca cctcgaccca aacccacaca ccaggcacct cagacaaagt
     1921 ggtacacgcc aattaagggt cgtctggatg cactctgggc attgatcttg aagcagtacg
     1981 accgggtgtc cttgatgaga ccccaggaag gcgatgaggg acggtgcata aacttctccc
     2041 gagttccaca tcaataagac gggaagcaag aagaatgaga agaatgagaa gaagacagcg
     2101 tttcttcatg atgctgattt ccaacagaat ggacagtcta gtgcatctcg gaagctcttg
     2161 ggacaacagc ccattttctc tctgtcagga aatgtttcct ctgccttctg ctttctgtac
     2221 accaaacatt ttcaaacact tgttctgcca tcgacaagag agttgatgaa ggtcgtcggg
     2281 gatagcccat gactcacgac actgaaaatc ccaaggaatg ttaatttgca tgctacagtt
     2341 tatgcaaagc tcctttgact gtgtaggagg acaaagcaga cactttgacg atgtgaagat
     2401 accaaagcca gaactacaca tctaccagcc acgaaggttt gcaatggaga acggtacttt
     2461 ggacatggac gtgtggcgca tgcgcttttg tttggcccga tctttagcta caagcaaaac
     2521 atgaaatttc ccaccaggct aaacagataa tggagcccac tgccttgtag ctatgtcagc
     2581 gagcaaagcc cttccaagtt gtcctccatt actttgtgcc ttacaggaaa tttctgacta
     2641 gaagatcttg tcaccgttac actgaaagtg ctcacgcatg acaaaatgta ggcgagacgc
     2701 cccaaggtac tggatgcaag caggactttg ccctttagtt tcccaagaca cctttctttc
     2761 attatgcact tgagacaaga gaattaatag agcgttaatt ccacaggaag accgcctcta
     2821 accatagacc tggagcacac agcataagga cttgtgattc aagaccttgt ccccagcctg
     2881 tgtagatccc ccttctcagc gtttgggtgt ttagccgtgc gtaaagcatt agtatctgta
     2941 aacacaacac ctaggtgttt gtttggcttt taatttaagg aagctgtatc cacaaagctt
     3001 ccgctcaggg ttttctcctt ccttccagtc tccgagggct cttcagcgtc acaagccagc
     3061 aactctcttt gcatgaaaat ttcaaagttt aattaatata attaaaggca acagcaagca
     3121 ccagcctgtg aagattttgc tcatcttttt tatgcctttt gacattgaat gacctatcac
     3181 tgtgtgcatg ttacttagcg atcaaggagc cgcgcacctc cgttgtgatt cagcctggga
     3241 aagagacctc ctcccttcag tttataaatt aaaagcagga ggggcgccat cagaaagcgt
     3301 cgacaatata catactataa attttttaga aatatcaaca tcgtgtcaca tcaacgatgc
     3361 caaattatgt tagcgtgagc agaaacacgg tgggggagga agcggtagca gctgaaggaa
     3421 atagctcaga taatccagtc actttcgata ctgtacttca gatgcgaaat ggatattcga
     3481 ctggaaacct gacaaagcgc gcctgctttg atgtgaactg gtatagacaa tgaccagcgg
     3541 ccgggtcagt gggatgtctc tctgtgagca cgaaggctta gcaaatgaca ctaaaaataa
     3601 gttcagccac cgtcacttgg gaagggagaa ggcgaacatt tcatgtttgg cgggcatgtg
     3661 tgtgcacaag atggaaagag cgctttagag catcctcatc taattaccca cgttgtgctc
     3721 tccatggtaa tttccaagga ccgcagtgat cctcttcact ggcgtccggg tctgtggcac
     3781 tgctccaaga agccttacgc gcacacacaa ataaacaaat gcacacacac acacactcta
     3841 gcttcgatct ttttgcgcta ccttatttat gtcaccgact ggctggatcc agaagtcaca
     3901 cctctccata ttagtgaata aaaattttac ccgtg
//
