LOCUS       NM_001044249            3384 bp    mRNA    linear   ROD 05-DEC-2024
DEFINITION  Rattus norvegicus ANTXR cell adhesion molecule 1 (Antxr1), mRNA.
ACCESSION   NM_001044249 XM_001074844 XM_342718
VERSION     NM_001044249.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3384)
  AUTHORS   Cheng,B., Liu,Y., Zhao,Y., Li,Q., Liu,Y., Wang,J., Chen,Y. and
            Zhang,M.
  TITLE     The role of anthrax toxin protein receptor 1 as a new mechanosensor
            molecule and its mechanotransduction in BMSCs under hydrostatic
            pressure
  JOURNAL   Sci Rep 9 (1), 12642 (2019)
   PUBMED   31477767
  REMARK    GeneRIF: The role of anthrax toxin protein receptor 1 as a new
            mechanosensor molecule and its mechanotransduction in BMSCs under
            hydrostatic pressure.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3384)
  AUTHORS   Besschetnova,T.Y., Ichimura,T., Katebi,N., St Croix,B.,
            Bonventre,J.V. and Olsen,B.R.
  TITLE     Regulatory mechanisms of anthrax toxin receptor 1-dependent
            vascular and connective tissue homeostasis
  JOURNAL   Matrix Biol 42, 56-73 (2015)
   PUBMED   25572963
REFERENCE   3  (bases 1 to 3384)
  AUTHORS   Stranecky,V., Hoischen,A., Hartmannova,H., Zaki,M.S., Chaudhary,A.,
            Zudaire,E., Noskova,L., Baresova,V., Pristoupilova,A., Hodanova,K.,
            Sovova,J., Hulkova,H., Piherova,L., Hehir-Kwa,J.Y., de Silva,D.,
            Senanayake,M.P., Farrag,S., Zeman,J., Martasek,P., Baxova,A.,
            Afifi,H.H., St Croix,B., Brunner,H.G., Temtamy,S. and Kmoch,S.
  TITLE     Mutations in ANTXR1 cause GAPO syndrome
  JOURNAL   Am J Hum Genet 92 (5), 792-799 (2013)
   PUBMED   23602711
REFERENCE   4  (bases 1 to 3384)
  AUTHORS   Opoku-Darko,M., Yuen,C., Gratton,K., Sampson,E. and Bathe,O.F.
  TITLE     Tumor endothelial marker 8 overexpression in breast cancer cells
            enhances tumor growth and metastasis
  JOURNAL   Cancer Invest 29 (10), 676-682 (2011)
   PUBMED   22085271
REFERENCE   5  (bases 1 to 3384)
  AUTHORS   Gutwein,L.G., Al-Quran,S.Z., Fernando,S., Fletcher,B.S.,
            Copeland,E.M. and Grobmyer,S.R.
  TITLE     Tumor endothelial marker 8 expression in triple-negative breast
            cancer
  JOURNAL   Anticancer Res 31 (10), 3417-3422 (2011)
   PUBMED   21965755
REFERENCE   6  (bases 1 to 3384)
  AUTHORS   Teckchandani,A., Toida,N., Goodchild,J., Henderson,C., Watts,J.,
            Wollscheid,B. and Cooper,J.A.
  TITLE     Quantitative proteomics identifies a Dab2/integrin module
            regulating cell migration
  JOURNAL   J Cell Biol 186 (1), 99-111 (2009)
   PUBMED   19581412
REFERENCE   7  (bases 1 to 3384)
  AUTHORS   Fernando,S. and Fletcher,B.S.
  TITLE     Targeting tumor endothelial marker 8 in the tumor vasculature of
            colorectal carcinomas in mice
  JOURNAL   Cancer Res 69 (12), 5126-5132 (2009)
   PUBMED   19528090
REFERENCE   8  (bases 1 to 3384)
  AUTHORS   Ruan,Z., Yang,Z., Wang,Y., Wang,H., Chen,Y., Shang,X., Yang,C.,
            Guo,S., Han,J., Liang,H. and Wu,Y.
  TITLE     DNA vaccine against tumor endothelial marker 8 inhibits tumor
            angiogenesis and growth
  JOURNAL   J Immunother 32 (5), 486-491 (2009)
   PUBMED   19609240
REFERENCE   9  (bases 1 to 3384)
  AUTHORS   Davies,G., Rmali,K.A., Watkins,G., Mansel,R.E., Mason,M.D. and
            Jiang,W.G.
  TITLE     Elevated levels of tumour endothelial marker-8 in human breast
            cancer and its clinical significance
  JOURNAL   Int J Oncol 29 (5), 1311-1317 (2006)
   PUBMED   17016666
REFERENCE   10 (bases 1 to 3384)
  AUTHORS   Werner,E., Kowalczyk,A.P. and Faundez,V.
  TITLE     Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell
            spreading by coupling extracellular ligands to the actin
            cytoskeleton
  JOURNAL   J Biol Chem 281 (32), 23227-23236 (2006)
   PUBMED   16762926
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC131853.1.
            
            On Feb 11, 2007 this sequence version replaced NM_001044249.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC131853.1, DQ789143.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5756307,
                                           SAMEA5760383 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3384
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..3384
                     /gene="Antxr1"
                     /note="ANTXR cell adhesion molecule 1"
                     /db_xref="GeneID:362393"
                     /db_xref="RGD:1307144"
     exon            1..539
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     CDS             352..2082
                     /gene="Antxr1"
                     /note="tumor endothelial marker 8; anthrax toxin receptor
                     1"
                     /codon_start=1
                     /product="anthrax toxin receptor 1 precursor"
                     /protein_id="NP_001037714.1"
                     /db_xref="GeneID:362393"
                     /db_xref="RGD:1307144"
                     /translation="MSHGRQRGQRSSCSMDRAGRLGTGLRGLCVAALVLVCAGQGGRR
                     EDGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHRFISPQLRMSFIVFSTRGT
                     TLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENSQGYRTASVIIAL
                     TDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQ
                     ALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINDS
                     VTLNEKPFAVEDTYLLCPAPILKEVGMKAALQVSMNDGLSFISSSVIITTTHCSDGSI
                     LAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPVEESEEEDDDGLPKKKWPTVDA
                     SYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMR
                     RPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVKNSQPAKYP
                     LNNSYHSSSPPPAPIYTPPPPAPHCPPPAPSAPTPPIPSPPSTLPPPPQAPPPNRAPP
                     PSRPPPRPSV"
     exon            540..611
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            612..683
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            684..765
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            766..799
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            800..879
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            880..948
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1029
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1090
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1189
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1259
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1260..1338
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1339..1434
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1476
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..1572
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1740
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1741..1821
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1822..3327
                     /gene="Antxr1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaagaaaga aaggagggga agaaggggag ggagcaaaga caccgcactg ccccaaccaa
       61 gaacaatttg aaaacccacc ccatcatact taaaaatcta ggacaaagag ccgtcgggac
      121 ggaactgctt cgactgcaaa gcttcgagcg cagcttggga gccgcctggt ggcccgagcc
      181 cgagagctcc acagagcaga gcgccctggg gtccctgaaa ctcgaaaccc gggcgctgaa
      241 ccggcggaaa ctaaagcgaa atccttgaac ttctctggac aattgcttcc gggcgtttgc
      301 agagagccga gggacctgac gggagcccag gccgcgtatg gcgcgcccct gatgtcccac
      361 ggacgccagc gaggccagcg ctccagctgc agcatggacc gcgcggggcg cctgggcacg
      421 ggcctgcggg gactctgcgt ggctgcgctc gtgctcgtgt gcgccggaca agggggccgc
      481 cgagaggacg ggggaccagc ttgctacggg ggattcgacc tctacttcat cctagacaag
      541 tcaggaagcg tgctgcacca ctggaatgag atctactact ttgtggagca gctggctcat
      601 agattcatca gcccacagct aaggatgtcc ttcattgtct tttctactcg agggacaact
      661 ttaatgaaac taactgagga cagggaacag atccggcaag gcctcgagga gctccagaag
      721 gttctgccag gaggagacac ttacatgcat gaaggattcg agagggccag tgagcagatt
      781 tactacgaga acagtcaagg atacaggaca gcaagtgtca tcattgctct gacggatggg
      841 gagctgcacg aggacctctt cttctattcg gagagggagg ctaacagatc ccgagacctt
      901 ggcgcgatcg tctactgcgt tggcgtgaag gatttcaatg aaactcagtt ggctcggatt
      961 gcagacagta aggaccacgt ctttcctgtg aatgacggct tccaggctct ccagggcatc
     1021 atccactcga ttttaaagaa atcctgcatt gaaattctag cagctgaacc ttccaccatc
     1081 tgcgcagggg agtcctttca agtggttgtg agaggaaatg gctttcgaca cgcccgcaat
     1141 gtggacaggg tcctctgcag cttcaaaatc aacgattcgg ttacactcaa tgagaagccc
     1201 tttgctgtag aagatactta cttgctgtgc ccagcaccaa tcttaaaaga agttggcatg
     1261 aaggctgcac tgcaggtcag catgaatgac ggcctgtcct tcatctccag ctccgtcatc
     1321 atcaccacca cacactgttc agacggctcc atcctggcga ttgctctgct gatcctcttc
     1381 ctgctgctgg ccctggcgct gctctggtgg ttctggcccc tctgctgcac agtgatcatt
     1441 aaggaggtcc ctccaccccc ggttgaggag agtgaggaag aagacgatga tggtttgcca
     1501 aagaagaaat ggcccacggt agacgcctct tactacggtg gacgaggtgt tggaggcatt
     1561 aaaagaatgg aggttcgctg gggagaaaag ggctccacag aagaaggggc gaagctagaa
     1621 aaggcaaaga acgcaagagt caagatgcct gagcaggagt atgagttccc ggaacctcgg
     1681 aacctcaaca acaacatgcg ccggccttcg tccccccgga agtggtactc ccccatcaag
     1741 ggaaaactcg atgccttgtg ggttctgctg agaaaagggt atgatcgagt gtctgtgatg
     1801 aggccacagc cgggagacac ggggcgctgt atcaacttca ccagagtgaa gaacagtcaa
     1861 ccagccaagt atcccctcaa caactcgtac cactccagct ccccgcctcc cgctcccatc
     1921 tacacacccc caccccctgc tccccactgc cctcccccag cccccagtgc ccccactcct
     1981 cccatccctt ccccaccctc cactctaccc cctcctcctc aggctccacc ccctaacagg
     2041 gcaccacccc cctcccgacc tcctccaaga ccttctgtct agaacccaaa gtccaagctc
     2101 tgggctccct gagcaactcc agcaggaggc tcctctgctg acagaaagat ctgcccagcc
     2161 tacgtggtaa gcggcgcctg atgtttgcgc aatttaaaag caagtcgtga tgggcagaac
     2221 aaaatgggaa ttttttaact gcctgaagac agacaatgag acaatgacag tcccattata
     2281 gcctgtgacc cctcacctct agaggaaggt tccagagatg gccacattgc cacgatgctc
     2341 tcagccagat tatgtcccat ggagacgagg aagaaagtga tttctgagaa tggaatgcag
     2401 cattggataa gaaacatcct ggctgagact gagtgccatc tcactgactt gactcttgac
     2461 ccttggactg ggaaccaggc tgtccttacc cctgggtacc atcaccagca actctgaaaa
     2521 cgtgtggtgt ccctagtgtg catcaaatag atatccagct gggatctgca ggttgccctt
     2581 tgtaagaaca tatactctct tctctttccc agacttcctg gcttcccagt gaggaggggc
     2641 agggaaaggc gttgccgtgc ttagaagtta gagaaaatca gtgcttagca ctgataggaa
     2701 attgttgatg ggagcttcca gctcttacat ctataaatgg ccgacttcag ccagtcacag
     2761 ttccaaaacc aacaaacctt gtcattgtta aaggcaaact gctaaggagt cacattgaca
     2821 ccaaggttgg ctgtggcata tatcagagct gaccatacag aaccttcccc atgagatctc
     2881 aaggccctcc atcttcagca cgccagctaa gagacagtag gcctgacttg gtaaggaaac
     2941 catgcccagt tgattttact ctgaaacggg ccattgtatg tatggtatat ctctccttgg
     3001 cttttcgacc tgctcacaaa cagcaccagt tatgaaacaa ggagaaatac atcccttgta
     3061 taacagaaaa gctctgcctg aatcaccacc ccactcctcc acatttttcc gaagctactt
     3121 gatcagtgag ctctttaact ttatgttaac cctggatgga cactgtcacc caaccatgaa
     3181 aacaaaggtc attgtcaaag acagtgtaca gcccatccaa aatgatgctt ccttcctcag
     3241 ttttccacag gccccagaat tcctgtctca ggctctctaa actctttcgc agaacaaaag
     3301 atataataaa gtgagcagaa gtttttaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     3361 aaaaaaaaaa aaaaaaaaaa aaaa
//
