LOCUS       XM_006229407            3734 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus alanyl aminopeptidase, membrane
            (Anpep), transcript variant X3, mRNA.
ACCESSION   XM_006229407
VERSION     XM_006229407.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006229407.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006229407.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3734
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3734
                     /gene="Anpep"
                     /gene_synonym="AP-M; AP-N; Apm; Apn; KZP; Lap1; rAPN"
                     /note="alanyl aminopeptidase, membrane; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 4 mRNAs, 124 ESTs, 8 Proteins, and 99% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     79 samples with support for all annotated introns"
                     /db_xref="GeneID:81641"
                     /db_xref="RGD:2991"
     CDS             435..3332
                     /gene="Anpep"
                     /gene_synonym="AP-M; AP-N; Apm; Apn; KZP; Lap1; rAPN"
                     /codon_start=1
                     /product="aminopeptidase N isoform X1"
                     /protein_id="XP_006229469.1"
                     /db_xref="GeneID:81641"
                     /db_xref="RGD:2991"
                     /translation="MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENS
                     AIAPTLPGSTSATTSTTNPAIDESKPWNQYRLPKTLIPDSYQVTLRPYLTPNEQGLYI
                     FKGSSTVRFTCNETTNVIIIHSKKLNYTNKGNHRVALRALGDTPAPNIDTTELVERTE
                     YLVVHLQGSLVKGHQYEMDSEFQGELADDLAGFYRSEYMEGGNKKVVATTQMQAADAR
                     KSFPCFDEPAMKASFNITLIHPNNLTALSNMLPKDSRTLQEDPSWNVTEFHPTPKMST
                     YLLAYIVSEFKYVEAVSPNRVQIRIWARPSAIDEGHGDYALQVTGPILNFFAQHYNTA
                     YPLEKSDQIALPDFNAGAMENWGLVTYRESALVFDPQSSSISNKERVVTVIAHELAHQ
                     WFGNLVTVDWWNDLWLNEGFASYVEFLGADYAEPTWNLKDLIVLNDVYRVMAVDALAS
                     SHPLSSPANEVNTPAQISELFDSITYSKGASVLRMLSSFLTEDLFKKGLSSYLHTFQY
                     SNTIYLDLWEHLQQAVDSQTAIKLPASVSTIMDRWILQMGFPVITVNTSTGEIYQEHF
                     LLDPTSKPTRPSDFNYLWIVPIPYLKNGKEDHYWLETEKNQSAEFQTSSNEWLLLNIN
                     VTGYYQVNYDENNWRKIQNQLQTDLSVIPVINRAQIIHDSFNLASAGKLSITLPLSNT
                     LFLASETEYMPWEAALSSLNYFKLMFDRSEVYGPMKRYLKKQVTPLFAYFKIKTNNWL
                     DRPPTLMEQYNEINAISTACSSGLEECRDLVVGLYSQWMNNSDNNPIHPNLRSTVYCN
                     AIAFGGEEEWNFAWEQFRKATVVNEADKLRSALACSNEVWILNRYLSYTLNPDYIRKQ
                     DATSTIVSIANNVVGQTLVWDFVRSNWKKLFEDYGGGSFSFANLIQGVTRRFSSEFEL
                     QQLEQFKEDNSATGFGSGTRALEQALEKTKANIKWVKENKDVVLKWFTENS"
ORIGIN      
        1 taacccgcgg ggccgggcgg gcgggcggcg gcaaggcagg agcagctcgg agcagcgcgc
       61 tgtcctagga agattagtgt caccgccttt ccccctgcct ctgggtgcca agcctgcagc
      121 ctgcccgtca gccccagctc cagctgatcc cccaccatcc aggtcgcctg cagcctgtaa
      181 ctacccactg tgttggttac agcagtcatc tatcccgtgc gccctgaagc cagctctgta
      241 cagtttcgtt tctgatctct ccagagccca agcagagtag acccctgtcc agcctagtga
      301 ccttcgcctg agcgctggtt aatatttgac caaaggcggt ggggctcctc cccctgggaa
      361 gatataagct ggtctggggc tactctgctt tcttcttggc ctgagctgtt ccgagctccc
      421 tgcccaccag catcatggcc aagggtttct acatttccaa gaccctgggc atcttgggca
      481 tcctgttagg tgtggcagcc gtatgcacca tcatagctct gtcggtggtc tacgctcagg
      541 agaagaacag gaatgcggag aactctgcca tagcccccac gctcccaggc agcacctcag
      601 ccaccacctc aactaccaac cctgctatag atgaaagcaa accttggaac cagtatcgct
      661 tgcctaagac tcttataccc gactcctacc aggtgacctt gaggccttac ctcaccccca
      721 acgagcaggg cctgtacatc ttcaaaggtt ccagtactgt ccgctttacc tgcaacgaga
      781 ccacaaatgt catcatcatc cacagcaaga agctcaacta caccaacaaa gggaaccaca
      841 gggtggcgtt gcgagccctg ggtgacactc cggcacctaa catcgacaca acggaactgg
      901 tagagcgcac ggagtacctg gtggtgcacc tgcagggctc cctggtaaag ggccatcagt
      961 acgagatgga cagtgagttc cagggggagc tggctgatga tctggctggc ttctaccgca
     1021 gcgagtacat ggaaggtggc aacaagaaag tggtggccac cacacagatg caggctgccg
     1081 atgctcgaaa atcctttcct tgcttcgatg agccagccat gaaggcctca ttcaacatca
     1141 cgctcatcca ccccaacaac ctcaccgctc tgtctaacat gcttcccaaa gattccagga
     1201 cccttcagga agatccttcc tggaacgtca ctgagttcca ccctaccccg aagatgtcca
     1261 catacctgct ggcctatatc gtgagcgagt tcaaatatgt agaagccgtc tcacccaata
     1321 gagtccagat tcgaatctgg gctcggccca gtgccattga tgagggccat ggtgattacg
     1381 ctctgcaagt cacaggccct atcctaaact tctttgccca acattataat acagcctacc
     1441 ctctagaaaa atctgaccag attgccctgc ctgacttcaa cgctggagcc atggagaact
     1501 gggggctcgt gacctaccga gagagtgccc tggtctttga ccctcagtcc tcctccatta
     1561 gcaacaagga gcgggtggtc actgtgattg cccatgagct ggcccatcag tggtttggca
     1621 acctggtgac cgtggattgg tggaatgacc tgtggctgaa cgagggcttt gcctcctatg
     1681 tggaatttct gggtgctgac tatgcagagc ccacctggaa tctgaaagac ctcatagtac
     1741 tgaatgatgt gtaccgtgtg atggccgtgg acgcgctcgc ttcctcccac ccgttgtcca
     1801 gccctgccaa cgaggtcaac acgccagccc agatcagtga gctgtttgac agcatcacct
     1861 acagcaaggg agcctcagtc cttaggatgt tgtccagctt cctgacagag gacctgttca
     1921 agaagggcct ttcgtcttac ctccacacct tccaatactc gaacaccatt tatctggacc
     1981 tgtgggaaca ccttcagcag gcagtggaca gtcagacagc tatcaaactc ccagcctcag
     2041 tgagcaccat catggaccga tggattctac agatgggttt tcctgttatc actgtgaaca
     2101 ccagtacggg agaaatctac caggaacact tcctcctgga ccccacttcc aaacctaccc
     2161 gcccctcaga ttttaattac ctctggattg tgcccattcc gtatctcaaa aatggaaagg
     2221 aggatcacta ctggctggag accgagaaaa accagagtgc agaattccaa acatcctcca
     2281 atgaatggct cttactgaac attaatgtaa ccggctacta ccaggttaac tatgatgaaa
     2341 acaactggag gaagattcag aatcagctgc aaacagacct ttctgttatc cctgtcatca
     2401 accgtgcgca gattatccac gactccttca acctagccag tgctggaaag ctatccatca
     2461 ctctgccgct gagcaacacc ctcttcctgg ccagtgaaac agaatacatg ccctgggagg
     2521 ctgccctgag cagcctgaac tacttcaagc tcatgtttga ccgctcggag gtctacggcc
     2581 ccatgaagcg ctatctgaag aagcaagtca cacccctctt cgcctacttc aaaatcaaaa
     2641 ccaacaactg gctcgaccgt cctccaacac tgatggagca gtacaacgaa attaatgcca
     2701 tcagcaccgc ctgttctagt ggtctcgaag agtgtaggga tctcgttgtt gggctttata
     2761 gtcagtggat gaacaactct gataataacc cgatccaccc caaccttcgg tctactgtct
     2821 actgcaatgc cattgctttc ggtggtgagg aagagtggaa ctttgcttgg gaacagttcc
     2881 ggaaagcaac tgtggtgaac gaggcagata aactccgctc agccttggcc tgtagcaacg
     2941 aggtgtggat tttgaacagg tacctgagtt acactctgaa ccccgactac atccggaagc
     3001 aggatgctac ctccaccatc gtcagcatcg ccaacaacgt ggttggacaa actctagttt
     3061 gggactttgt ccgaagcaac tggaagaaac tgtttgaaga ttacggcgga ggatctttct
     3121 cctttgccaa tctcatccag ggagtgaccc ggcgcttctc ctctgagttc gagctgcagc
     3181 agctggagca gtttaaagag gacaactcgg ccacaggctt tggctccggc actcgggctc
     3241 tggagcaagc cctggagaag actaaagcca acatcaagtg ggtgaaggag aacaaagacg
     3301 tggtactcaa gtggttcaca gaaaacagct agttagtccc gggccgagaa ccatctgtcc
     3361 cggcgtgacg cctatgacta tctcagcagc ctgtgcaggg tctctgtctt cagagcgcca
     3421 gacaccggca tctgaccctc aaggtcaaag tctccagcct atggagctag cctagctcct
     3481 aattgtcaga ctgccagaca cctcccggtc cttgcccctc gtgccaactc tgccccaggc
     3541 ccaggcctct ggggctgatc tcagggaagc ccagctctga gtctagattt actggacaaa
     3601 gggtagccta gaaagagtct ccctgaatgc cttactactt tccccccaca agacccagaa
     3661 ccaaagaatc aacagggcac aaagatctat atatattttt aagagaaaat gtaaataaag
     3721 aatttctaaa atga
//
