LOCUS       NM_012903               2017 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus acidic nuclear phosphoprotein 32 family member A
            (Anp32a), mRNA.
ACCESSION   NM_012903 XM_001075603
VERSION     NM_012903.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2017)
  AUTHORS   Sun,D., McGinn,M., Hankins,J.E., Mays,K.M., Rolfe,A. and
            Colello,R.J.
  TITLE     Aging- and injury-related differential apoptotic response in the
            dentate gyrus of the hippocampus in rats following brain trauma
  JOURNAL   Front Aging Neurosci 5, 95 (2013)
   PUBMED   24385964
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2017)
  AUTHORS   Natalizio,B.J. and Wente,S.R.
  TITLE     Postage for the messenger: designating routes for nuclear mRNA
            export
  JOURNAL   Trends Cell Biol 23 (8), 365-373 (2013)
   PUBMED   23583578
  REMARK    Review article
REFERENCE   3  (bases 1 to 2017)
  AUTHORS   Khan,M.Z., Vaidya,A. and Meucci,O.
  TITLE     CXCL12-mediated regulation of ANP32A/Lanp, a component of the
            inhibitor of histone acetyl transferase (INHAT) complex, in
            cortical neurons
  JOURNAL   J Neuroimmune Pharmacol 6 (1), 163-170 (2011)
   PUBMED   20617464
  REMARK    GeneRIF: these findings suggest that Lanp can interact with Rb in
            both young and mature neurons and is implicated in the regulation
            of neuronal survival by CXCL12/CXCR4
REFERENCE   4  (bases 1 to 2017)
  AUTHORS   Kular,R.K., Cvetanovic,M., Siferd,S., Kini,A.R. and Opal,P.
  TITLE     Neuronal differentiation is regulated by leucine-rich acidic
            nuclear protein (LANP), a member of the inhibitor of histone
            acetyltransferase complex
  JOURNAL   J Biol Chem 284 (12), 7783-7792 (2009)
   PUBMED   19136565
  REMARK    GeneRIF: LANP directly regulates expression of the neurofilament
            light chain, an important neuron-specific cytoskeletal gene, by
            binding to the promoter of this gene and modulating histone
            acetylation levels
REFERENCE   5  (bases 1 to 2017)
  AUTHORS   Cui,C.P., Wei,P., Liu,Y., Zhang,D.J., Wang,L.S. and Wu,C.T.
  TITLE     The protective role of Hepatopoietin Cn on liver injury induced by
            carbon tetrachloride in rats*
  JOURNAL   Hepatol Res 39 (2), 200-206 (2009)
   PUBMED   19054144
REFERENCE   6  (bases 1 to 2017)
  AUTHORS   Mutz,D., Weise,C., Mechai,N., Hofmann,W., Horstkorte,R., Bruning,G.
            and Danker,K.
  TITLE     Integrin alpha3beta1 interacts with I1PP2A/lanp and phosphatase PP1
  JOURNAL   J Neurosci Res 84 (8), 1759-1770 (2006)
   PUBMED   17016859
REFERENCE   7  (bases 1 to 2017)
  AUTHORS   Buttner,B., Kannicht,C., Reutter,W. and Horstkorte,R.
  TITLE     Novel cytosolic binding partners of the neural cell adhesion
            molecule: mapping the binding domains of PLC gamma, LANP, TOAD-64,
            syndapin, PP1, and PP2A
  JOURNAL   Biochemistry 44 (18), 6938-6947 (2005)
   PUBMED   15865439
  REMARK    GeneRIF: LANP interacts directly with the cytosolic domains of rat
            brain neural cell adhesion molecule (NCAM) 140 and 180 isoforms.
REFERENCE   8  (bases 1 to 2017)
  AUTHORS   Matilla,A. and Radrizzani,M.
  TITLE     The Anp32 family of proteins containing leucine-rich repeats
  JOURNAL   Cerebellum 4 (1), 7-18 (2005)
   PUBMED   15895553
  REMARK    Review article
REFERENCE   9  (bases 1 to 2017)
  AUTHORS   Matsuoka,K., Taoka,M., Satozawa,N., Nakayama,H., Ichimura,T.,
            Takahashi,N., Yamakuni,T., Song,S.Y. and Isobe,T.
  TITLE     A nuclear factor containing the leucine-rich repeats expressed in
            murine cerebellar neurons
  JOURNAL   Proc Natl Acad Sci U S A 91 (21), 9670-9674 (1994)
   PUBMED   7937870
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On May 10, 2023 this sequence version replaced NM_012903.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582424.988559.1,
                                           SRR26643299.35586.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-173               JAXUCZ010000008.1  71724578-71724750
            174-323             JAXUCZ010000008.1  71753482-71753631
            324-446             JAXUCZ010000008.1  71753789-71753911
            447-639             JAXUCZ010000008.1  71755782-71755974
            640-737             JAXUCZ010000008.1  71756954-71757051
            738-801             JAXUCZ010000008.1  71759457-71759520
            802-2017            JAXUCZ010000008.1  71759707-71760922
FEATURES             Location/Qualifiers
     source          1..2017
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..2017
                     /gene="Anp32a"
                     /gene_synonym="Anp32; LANP"
                     /note="acidic nuclear phosphoprotein 32 family member A"
                     /db_xref="GeneID:25379"
                     /db_xref="RGD:11508551"
     exon            1..173
                     /gene="Anp32a"
                     /gene_synonym="Anp32; LANP"
                     /inference="alignment:Splign:2.1.0"
     CDS             120..863
                     /gene="Anp32a"
                     /gene_synonym="Anp32; LANP"
                     /note="Acid nuclear phosphoprotein 32 (leucine rich);
                     leucine-rich acidic nuclear protein LANP; acidic
                     (leucine-rich) nuclear phosphoprotein 32 family, member A"
                     /codon_start=1
                     /product="acidic leucine-rich nuclear phosphoprotein 32
                     family member A"
                     /protein_id="NP_037035.2"
                     /db_xref="GeneID:25379"
                     /db_xref="RGD:11508551"
                     /translation="MEMDKRIYLELRNRTPSDVKELVLDNCRSIEGKIEGLTDEFEEL
                     EFLSTINVGLTSISNLPKLNKLKKLELSENRISGDLEVLAEKCPNLKHLNLSGNKIKD
                     LSTIEPLKKLENLKSLDLFNCEVTNLNAYRENVFKLLPQVMYLDGYDRDNKEAPDSDV
                     EGYVEDDDEEDEDEEEYDEYAQLVEDEEEEDEEEEGEEEDVSGEEEEDEEGYNDGEVD
                     DEEDEEDAAEEEGSQKRKREPDDEGEEDD"
     exon            174..323
                     /gene="Anp32a"
                     /gene_synonym="Anp32; LANP"
                     /inference="alignment:Splign:2.1.0"
     exon            324..446
                     /gene="Anp32a"
                     /gene_synonym="Anp32; LANP"
                     /inference="alignment:Splign:2.1.0"
     exon            447..639
                     /gene="Anp32a"
                     /gene_synonym="Anp32; LANP"
                     /inference="alignment:Splign:2.1.0"
     exon            640..737
                     /gene="Anp32a"
                     /gene_synonym="Anp32; LANP"
                     /inference="alignment:Splign:2.1.0"
     exon            738..801
                     /gene="Anp32a"
                     /gene_synonym="Anp32; LANP"
                     /inference="alignment:Splign:2.1.0"
     exon            802..2017
                     /gene="Anp32a"
                     /gene_synonym="Anp32; LANP"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagaaccgag cggagctggt tgagccttca aagtcctaaa acgcgcggcc gtgggttcgg
       61 ggtttattga ttgaattccg ctggcgcagg atcctctgca gaaagagaga gcgcgagaga
      121 tggagatgga caaacggatt tatttagagc tgcggaacag gacgccctct gatgtgaaag
      181 agctggtcct ggataactgt cggtcaattg aaggcaaaat cgaaggcctc acggatgagt
      241 ttgaagaact ggaattccta agtacaatca acgtaggcct cacctccatt tccaacttac
      301 caaagttaaa caaactcaag aagcttgaat taagcgaaaa cagaatctca ggggacctgg
      361 aagtattggc agagaaatgt ccgaacctta agcatctaaa tttaagtggc aacaaaataa
      421 aagatctcag cacaatagag ccgctgaaga agttagagaa tctcaagagc ctagacctgt
      481 ttaactgtga ggtgaccaac ctgaatgcct accgagaaaa cgtgttcaag ctcctgcccc
      541 aggtcatgta cctcgatggc tatgacagag acaacaagga ggcccctgac tctgatgttg
      601 agggctacgt ggaggatgac gacgaggaag atgaggatga ggaggagtat gatgaatacg
      661 cccagctagt ggaagatgaa gaggaagagg atgaggagga agaaggggag gaagaggacg
      721 tgagtggaga ggaagaggag gatgaagaag gttacaacga cggggaagtg gatgatgagg
      781 aagatgaaga agatgctgct gaagaagaag ggagtcagaa gcgaaaacga gagcccgatg
      841 acgagggcga agaggatgac taaggggaat taacctgttt ggggaaattc ctattgtgat
      901 ttgactgttt ttacccatat cccctccccc tcctattcct gccccccgaa acttattttt
      961 ttctgattgt agcgttgctg tgggaatgag aggggcaaag tgtactgggg attgccgggg
     1021 gtggggtggg ggtgggaggg gaggaataaa atactatttt tactgccaca ctttcttttc
     1081 ccccttcctt tttcctgtgt ctggttttgt ccccataact gcaatagctt agtgcacacc
     1141 aagcgtttgt tcttactctc cagagaggat ggcttggagg tctctaacct tttctggtat
     1201 gtcccacatc cccagagttg atcaggaggc cgtggctggc ctccaccagg tgactcacag
     1261 cccaagagcc gtcttcttca ctaactcctg ttctggttcg tgtggtcgct gccagaggca
     1321 cccagcaccc tggtttgtaa atagcaaccg aaaaggcgta ttttggcact ggtttgggga
     1381 cagtccccat ctctcacccc ctttccccct ccacagatgt cagtgcaaag agagctcttg
     1441 ttattctatg gctgtgatcc tgagagccaa aaagaaaaga aaagaaaaaa aaacagaaaa
     1501 caaaacaaca acaaaacgcg gcaggtttag gagacacgta aaatgggaaa gaagtgaacc
     1561 ttcgtgtttc agcttcttca gaaaagccaa cctgttctat cttgttctgt aaaatattag
     1621 agcaatttgt tttacagaaa tggcaggagg actcctcggg cgctccagct tagaaccttt
     1681 taacaaatct aagctctgga agcgccctgt gtgtcctctg ggttttggtt ctgtttgttt
     1741 tccttctcaa atacatagga gcacggaaaa ggaatgcaag ctcgtatttt cttacctggt
     1801 gggactctga agtggccgca gatttctcct agagagtgcg tgtgccttca gcgtccccct
     1861 tccagattgc tttagaagtg acgtgctgtt tcctaccctg tgtctcattt gtacagatca
     1921 gctgtaactc atttttctcc cgcccctgag aagagccaaa ctttgagttt tatgtctgtt
     1981 tgtcattgat aaatttcaat aaatcttttt tatacaa
//
