LOCUS       XM_006229266            8745 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus anoctamin 5 (Ano5), transcript variant
            X1, mRNA.
ACCESSION   XM_006229266
VERSION     XM_006229266.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006229266.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006229266.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8745
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..8745
                     /gene="Ano5"
                     /note="anoctamin 5; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 10 ESTs, 1 long SRA read,
                     2 Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 21 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:308637"
                     /db_xref="RGD:1564265"
     CDS             193..3945
                     /gene="Ano5"
                     /codon_start=1
                     /product="anoctamin-5 isoform X1"
                     /protein_id="XP_006229328.1"
                     /db_xref="GeneID:308637"
                     /db_xref="RGD:1564265"
                     /translation="MELGNQEGRKPGDSEESARAGVPRNADMVQEPEVPEDVAVGGAP
                     EEATRRVEGPGVSPNVHILSDPEGARRVFRYVDSGKISEEDQMENAEERRETVETILQ
                     VQESETGEESEVSEKISEEIPEGSSPARPKKRKYGQHSLEEQLGWQQDQRRDLGQPSQ
                     GEEQYLEPSVEGTEQGSHSKTMKPKSLTASLLKRRKSQGKYRLERKPSLLNRPESSAP
                     GTLSSAPGPSMAPRQSLTPLPSLALRSTLAHRADFALRSSQPPRVSLPFRASVVPPVP
                     LGLESHNSGTLRKESSGYILESDQKSRRQTIRFSLLPKSSRRLSQRSAGTCVSLISAY
                     NELAKLGDPDLLEMVEQEGLKVKEIDYALQRSESLGGKETSFLIPEDSQPLPEKRFNL
                     FLRRRLMFQRSEQSKDSVFFRDGIRQIDFVLSYVEDVKKDGELKAERRQTFEQNLRKT
                     GLELEIEDKMNSEDGKTYFVKIHAPWEVLVTYAEVLGIKMPIKLSDIPRPKYSPLSYM
                     LGPVKLPLGVKYPKPEYFTAQFSRHRQELFLIEDEATFFPSSTRNRIVYYILSRCPFG
                     EEEGKKKIGIERLLNTNTYLSAYPLHDGQYWRPSKTSRINERYVLCKNWARFSYFYKE
                     QPFDLIRNYYGEKIGIYFVFLGYYTEMLLFAALVGLACFIYGLLSMESNQTSIEICDP
                     NIGGQMIMCPLCDEVCDYWRLNTTCLHSKFSHLFDNESTVFFAIFMGIWVTLFLEFWK
                     QRQARLEYEWDLVDFEEEQQQLQLRPEFEAMCKHKKMNPVTQEMEPHMPLCHRIPWYF
                     VSGTTVTFGMALLLSSMVSIIVYRLSVFAIFASFMESEATLQSVKRFFTPQLATALSA
                     SCLNCLVILILNFFYEKISAWITKMEIPRTHQEYESSLTLKMFLFQFVNYYSSCFYVA
                     FFKGKFVGYPGRYTYMFNLWRSEECGPPGCLIELTTQLTIIMIGKQIFGNIHEACQPL
                     IFNWWRRRRTRTHSEKLYSRWEQDHDLQVYGHRGLFYEYLETVMQFGFVTLFVASFPL
                     APLFALMNNIMGIRVDAWKLTTQYRRPVAAKAHSIGVWQDILYGMAILSVATNAFIVS
                     FTSDIIPRLVYFYAYSKNSTEPLSGYINNSLSVFLIADFPNHTVPMEKKDFVTCRYRD
                     YRYPPDHKGKYGHNMQFWHVLAAKMTFIIVMEHIVFLFKFLLAWMIPDVPKDVAEKIK
                     REKLMTVKIIHDFELNKLKENLDVEYGNIMKNMSVNNKSLKAKTSV"
ORIGIN      
        1 gggaagaagg ttttgtccta gctggcttca ctttgagtgg agggccaggc aatccagggg
       61 aaccagactt actagtaggc tgaggctgcc taccagaggg gatgtgagga aaaaggttgg
      121 aaatggtgaa ctgtgggtac ctgccttgag tgggtagacc ggttgaaaca ggaagctcta
      181 agcctgttag gtatggagct ggggaatcaa gagggaagga agcctggaga ctccgaggaa
      241 tccgccaggg ctggggttcc taggaatgct gatatggtac aagaaccaga agttccagaa
      301 gatgtagctg tggggggagc ccctgaagag gccacaagga gggtggaggg gcctggagtc
      361 tccccgaatg tgcacatatt aagtgaccca gagggggcaa gaagagtctt caggtatgta
      421 gacagtggga aaatctctga ggaggaccaa atggaaaacg cggaggagag aagagaaaca
      481 gtggagacaa tactgcaagt ccaggagtcc gaaactgggg aggaatctga ggtgtctgaa
      541 aagatcagtg aggagatccc tgaggggagc tcaccagcaa ggccgaagaa gaggaagtat
      601 ggccagcaca gcctggagga gcaactgggc tggcagcaag atcagagaag ggatttaggc
      661 cagcctagcc agggtgagga gcagtactta gagcccagtg tggaggggac agagcagggc
      721 tctcactcaa agacaatgaa gcccaagagt ttaactgcca gtctgctgaa acgccgcaag
      781 agtcagggca agtaccgcct ggagaggaag cccagcttgc tgaaccgacc tgagtcttca
      841 gctccgggca ccttgtcctc ggctcctggc ccgtccatgg cgcctcgcca gtccctgaca
      901 cctctcccgt ccctggcact tcgctcgacc ctagctcacc gcgcggactt tgctttacgc
      961 tcctcccagc ctccccgggt gtcactaccg tttcgggcgt ctgtggtgcc tccggtgcct
     1021 ctgggtctgg agtcgcacaa ttcgggcacc ttgaggaagg agagctccgg ctacatactg
     1081 gagtcggatc agaaaagcag gcggcagacc atacgcttca gcctcctccc caagtcatct
     1141 cgccgcctgt cacagcggtc cgcaggcacc tgtgtctcgc tcatcagtgc ttacaacgag
     1201 ctggcaaagc tgggcgaccc cgacctgctg gagatggtgg agcaggaagg cttaaaagtt
     1261 aaagaaatag actatgctct ccaaaggagt gagagcctgg gcggcaaaga gaccagcttc
     1321 ctcatccctg aagactcaca gccactgccc gagaagcggt tcaatttgtt cctgaggagg
     1381 cgtctcatgt ttcagaggag cgaacaaagc aaagactcag tcttcttcag agatggaatc
     1441 cggcagattg acttcgtcct gtcctacgtg gaagatgtaa agaaagacgg agagctgaag
     1501 gcagaaagaa gacaaacgtt tgaacaaaat ctcagaaaaa caggtcttga gttggaaata
     1561 gaagacaaaa tgaattctga agatgggaaa acctattttg tgaagatcca cgctccgtgg
     1621 gaagtcctgg tcacttatgc tgaagtgctg ggaatcaaga tgcctattaa gttgagtgac
     1681 atcccacggc caaagtactc acccctgtct tacatgcttg gacctgtgaa gctcccattg
     1741 ggcgtgaagt accccaaacc tgagtatttc actgcccagt tcagcagaca tcgtcaggag
     1801 ctcttcctca tcgaagatga ggccactttc tttccatcct caacaaggaa cagaattgtt
     1861 tactatattc tgtcacgatg cccttttgga gaagaagagg gaaagaaaaa gattgggatt
     1921 gaaagactgc tgaacacgaa cacttattta tctgcctacc cgctccatga tggccagtat
     1981 tggaggccat caaaaacttc tcgaatcaat gaaaggtacg tcctttgcaa gaactgggct
     2041 cgattttcct acttttacaa ggagcaacct tttgatttga ttcggaatta ttatggagaa
     2101 aaaatcggta tctattttgt atttctcggg tattacacag aaatgctgtt gtttgcggct
     2161 ctggttggct tagcctgctt catctacggc ttgttatcaa tggaaagtaa ccaaactagc
     2221 attgaaatct gtgaccctaa cattggcggt cagatgatca tgtgcccact ctgtgatgaa
     2281 gtgtgtgact actggagact taacaccacg tgtttgcatt caaagttctc ccatctgttt
     2341 gataatgagt cgactgtgtt ctttgcgatc ttcatgggga tctgggtcac actgtttctg
     2401 gagttttgga aacagcgtca ggccaggctt gagtatgagt gggatctggt ggactttgaa
     2461 gaagaacagc agcaactcca gttgcggcct gaatttgaag ctatgtgtaa acacaagaag
     2521 atgaatcctg tgacacagga gatggagcca catatgcctc tgtgccatcg catcccctgg
     2581 tactttgtgt cagggaccac agtgaccttt gggatggccc tcctcctcag cagtatggtg
     2641 tccattatcg tgtaccgcct atcagtcttt gccatttttg ccagcttcat ggaaagtgaa
     2701 gccaccctgc agagcgtgaa gcgcttcttc accccgcagc tggccactgc tctctctgca
     2761 tcctgcctga actgccttgt catcttgata ctgaattttt tttatgagaa gatatctgcc
     2821 tggattacaa aaatggaaat acctcgaact caccaggagt atgagagcag cctcactctg
     2881 aagatgtttc tcttccagtt tgtgaactat tactcatctt gcttctatgt ggccttcttt
     2941 aaagggaaat tcgtgggata tcctggaagg tacacatata tgttcaacct atggagaagt
     3001 gaagagtgcg gtcctccagg ctgtctgata gagctgacca cccagctcac catcatcatg
     3061 attgggaaac agatttttgg aaacatccat gaagcctgtc aacccttgat ttttaattgg
     3121 tggagacgcc gaagaacccg gacccactct gagaaactgt acagtcgttg ggagcaagat
     3181 catgaccttc aggtttatgg acatcgtggg ctgttctatg agtacttgga aacagttatg
     3241 cagtttgggt ttgtcacgct gtttgtggcc tcttttcccc tggcacccct gtttgctctc
     3301 atgaacaaca tcatgggaat ccgagtggat gcctggaaac tgacaactca gtacaggaga
     3361 cctgtcgctg cgaaagctca ctccataggt gtctggcaag acattcttta cggaatggcc
     3421 atcctttctg ttgcaactaa tgccttcatt gtctcattca catctgacat catcccccgg
     3481 ttagtttact tctatgccta ctcaaagaat tccacagagc ccttgagtgg atacatcaat
     3541 aacagcctgt cagtgttcct gatagctgac tttcccaacc acacagtgcc catggagaaa
     3601 aaagacttcg tcacctgcag gtacagagat tataggtacc ctcctgatca caagggcaag
     3661 tatggccata acatgcaatt ctggcatgtc cttgccgcca agatgacctt catcatagta
     3721 atggaacaca ttgtgtttct gtttaaattt ttattggcct ggatgatacc agatgttcct
     3781 aaagacgtcg cggagaaaat caaacgagaa aagttaatga ctgtcaaaat aatccatgac
     3841 tttgagctca acaagttgaa agaaaacttg gacgttgaat atggtaacat catgaagaat
     3901 atgtcagtaa acaataaatc cctgaaggcc aaaacttcag tctaatccac acacaggtgg
     3961 agaagcttta tgcactttct ctgtccacgg ttgcctctgc tttttgggct ggatgctgga
     4021 agccatgtag ccatttgttt ttctttcctt cttttatttt taactcagtg tctttatgca
     4081 cttcaataga gactggcagt gtgctctcag aagagaatgt aggctggcac catccactgg
     4141 gtgattccag gaccctccgg ggtcctataa acagttatag gcggagcctg tggattcggc
     4201 atacgggaca tcatggattg ttgctaccta gatgaaacca tgacctgggg gaccaggtgc
     4261 tctgtcacta cccagggcaa ctgtacatct ctaccgtcaa ctcttgagtg tttcctgtct
     4321 cccaccagac aagaaaagga ttgtttcaaa gagaaaacta agcaaagaga tccaccaagt
     4381 cacaaaacat ctgctgttgt aaaatgcaca aatgaaagcg aaaatcagaa gtcttgggaa
     4441 atctcaccta ctaacaaaca ctgggtaaaa atgataggag cagtgtgcac ttaatgatgt
     4501 caggtgaaag gtagcttcaa tcagaatccc agatagcctt tcctaaaagt tgaattcctt
     4561 tccctatgag actaaatgaa tttttataaa agagagtcaa aaggctctta aaggtagtgt
     4621 ttccattctg ttgactgctt tcaacatcat ggtggctgca ggtctcgtaa gtgcaggtat
     4681 tgtgtgaagt cagcgtgtct tcttaagcgt taaagaattc aagacaacac atagagatta
     4741 actcatttga ttataaagtg gaacttttta aatttctctg aaatgctgat ttttgcatca
     4801 tgaagccttt ttgagctcta tccatttgta gaagttgggc acagtttaca aaatgtgact
     4861 ctttttgctc taaacaaact ctaaaccttg taagtttaca gtcttttcgt gggctacaca
     4921 gcccttcaac atctagtgcc ttctttctat gcccttgaca tatgaacaat tgtctaaatg
     4981 actgttgatt tgacatgata caacatttca gatgtcaact tgtcttctct tagagaaact
     5041 gtcagtgttg tgagcacaga gtttatcacc aaaacataat caacaacatg agaaggtgat
     5101 aggtaggaaa aagtctattt gttaaatgat cccttccaca cttttggcta tgtggatata
     5161 cctcgattct tgtcattggt tcagttaata cggtaccaca catgtgtctg catataactt
     5221 actactggac tgggagacat agtccagcta cagtatagtc gaatcttcag atttaaatta
     5281 gaattcagct atagaggagt attttttaaa atcacataca tacaaaaaat ttgatcacaa
     5341 gattttttaa aagtagtgtt tgcttaccaa taacacgatt tcacagcata gctgatatca
     5401 cagtattaac tactgataga cattaagtat ctaaaactag ggattatgga tattataaaa
     5461 atgataaaag agttagcaca tcacattatt gacaatgttg atttgtcaca tactaggtag
     5521 atttggaaac atgtttgggt cacttgaaat tatttcataa ttgagagata attttgttct
     5581 gtggagatgg tcaacataag acaaccagtc atcttgagga tgattctatc cacaggtgag
     5641 gttcttgtag cctatcaaat cacactgtca ccactgtgct tgtcacacac acagtgtaca
     5701 ttgccttctt catggtgcta tttttttaaa ggaagattgt aggtcttctt ttgttttatt
     5761 tttgtggctt gaaaatatta tgaagctaga ctgggagata aggccaaaga tgacttgcaa
     5821 agctgcccca cacactgcag gttcaaaatc tgcaatgcaa gcactgaata tccagagtaa
     5881 tggtagaaac gaacaaagct ggactttatc ctacagcaaa cacatccgaa gctttatctg
     5941 catcttcact ttcaagtgca ttgtcagata catcacattg gccttgtgat ttcccactga
     6001 gcactttcct ttgctttcat gactctgaga aactagagtc cctttctgga aagtctgtta
     6061 gccaaaatca ggtgtagttt gttccagcag aattgcttcg cttccaccgc cacattggtt
     6121 gatgtagcaa tgttaagcta gctgcgacag acacctgatg tatgctgggc caggatgtgt
     6181 taatacctca atcaaacagt taggcttcaa tgctaaagcc ccaaaccgca caactcattt
     6241 caaagtcgtc atcatcttca ttgattcttt tacacaaaac ccaaaatcct tcacgccact
     6301 tactttaggc atcaaaagaa ggggggctgt cattaaatga aatggtctga atttggcagt
     6361 gtttctggac tcctggattc cacacccttc ccgccctttc atcgtcaaga ggaaagacag
     6421 atctgtttcc tctgaatatc atgtgggatt ctttgggata cagctgtggg taagaataga
     6481 caaatctctc ctcactgcta tgccagttag taagggtgaa ataatatctg gagaaattcc
     6541 aggttgacaa ttagtgtgtg tcaaaagaaa gcctttactt gcagattgtg tttgtagagt
     6601 cattgactct gcgctccagc aataatggca ctggccattc aaaaagataa ctcattactt
     6661 cggacaaacc tctcatagtt attatgtaat tgaatgatgc catgaaggga ggcattggat
     6721 tgccagactt tggactctgc cacaaggaat caatagaact atcgtgttac tattcttgca
     6781 atttgaatgt acttttctgt atagtaatta aagtatgtca gttatttcag cactttgtaa
     6841 atgttaatga caacgtttaa aacataaggt atagtgtggt ctaaaccgtg cgagatacaa
     6901 gtgcccattc ctctaaatat gtcattggat gcaggctgca gctctcctga tatgagatgc
     6961 tgtgtcctga ggttaactct gggtttacaa gcttgctctt tcctcccgcc cttttcccct
     7021 ccattccacc ccattcttgc ttccatcctt tttctttgcc tccctccctc cctctctttc
     7081 tctttccttc cttccctttt ccttcctgta tttccttctg ttctctccta aaaggaggac
     7141 gtgggtattc agaaaaagtg gtctttagtt atagacttca aaagccaaat gactcagtga
     7201 gtaaagtagc aaataatttc aaatatgttg acacaaatat ccttttcatt tctctccatt
     7261 tcattattta ataacttccc tatactacag ctttttcctt ctccccgtct atttatcctt
     7321 ccaaactttg agggctttgt tttttaaacc attttagttc atttagtgct gtctgtatca
     7381 gcttgagttt agagctaatt tcttaaatga agaacttttg agaaggtttt tcatgagata
     7441 tgttgttttt cagacacttc tgagcacagc cagacacagg gttagctcag aatgtcactg
     7501 tatcaccctg aaagggcaga gtcaattagg agtagcttaa tgggtctaga gaaattgctg
     7561 taagcacttt gacagagact gccaaacagg cagcctggcc taccttgagt tgcacaaagt
     7621 cacttaggat cagggcagcc aagcctccac agctgctcta gtcctgtccc tcctatcaca
     7681 tccagagact ctcagttgga tagatttata cctctagttc ccacttatta aagatattat
     7741 attcactaca ttcaaccaat atacttttaa ggccagaatg ctcagaagtc aaatgattgc
     7801 accacatcct cagtacatta taggttgatc ataggatcat acaggatgta aatgatgaag
     7861 caaaattcta aatattatgg ggaaggcatt tcctttgaaa ttacagtctg ggataaaatg
     7921 tgccatcagg catgggcgtg aaacagcgga gctcctgaat agtgagtggc cttgtgtctt
     7981 ctattgctta tgtcaatctg caaccaagtt ccactgatgg gagtgcaggg ctcagcagga
     8041 ggggacatag gggagaaaag agagcaaaca aactcggtgg attgtatgtt cgtcatatca
     8101 tgctgatctt caagaatagt cacaaaaaga aaccttagct gctttgctgc catctgccat
     8161 tttggcaagt aagatctggt tacatttttc atctttgtga caaaataccc aaccaatgca
     8221 tattacggaa ggtgggattt atttgggctc actgcctgag gatttggctt atcatcatgg
     8281 ggaaaacatg gcaacagagc atgaggacag ctggtttcat tgcatctgta atcaggaggc
     8341 atgaatactg gtttattcag ttgggaaatc cagccaatat gatgatgcca cacatatcca
     8401 aggaaggtac cttcccgccc agctaaacgt acctggaaac acccagacgt gtgtttctag
     8461 tagcgattct aagaccagtc gaattgacag gattaaccat ctcagacctt ataggaaaag
     8521 atttcttgaa caaacaggca caggccacag ctatccctaa gcttaggaag gttataaacc
     8581 acacaaaaag catgttcaac aaactagatg tagtttactt ccataaagtg ctcccagtaa
     8641 ttgaaaaaca acaacctctt ctaactcaca ttctgaacaa cttaaatgtc tgatcgtgta
     8701 caatctcaaa accaaacaca accaataaac ttcaaagaac taaaa
//
