LOCUS       XM_017594729            4382 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus anoctamin 4 (Ano4), transcript variant
            X7, mRNA.
ACCESSION   XM_017594729
VERSION     XM_017594729.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051342.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_017594729.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4382
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4382
                     /gene="Ano4"
                     /gene_synonym="Tmem16d"
                     /note="anoctamin 4; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 3 ESTs, 8 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 32 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:299714"
                     /db_xref="RGD:1310252"
     CDS             1620..4382
                     /gene="Ano4"
                     /gene_synonym="Tmem16d"
                     /codon_start=1
                     /product="anoctamin-4 isoform X6"
                     /protein_id="XP_017450218.1"
                     /db_xref="GeneID:299714"
                     /db_xref="RGD:1310252"
                     /translation="MEASSSGITNGKNKVFHAVAKDVNIFFDELEAVNSPCKDDDSLL
                     HPGNLTSTSEDTSRLEAGGEKVRERNKSNGLYFRDGKCRIDYILVYRKSNPQTEKREV
                     FERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRR
                     YKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKDT
                     FFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIKTH
                     GAVNHRHLLYECWASWSVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGL
                     FVFLYGVTTLDHCQVSKEVCQATDIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGAT
                     VFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPI
                     SGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIR
                     NNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQF
                     VNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQT
                     WNNFMELGYPLIQNWWTRRKVRQEHGTERKINFPQWEKDYNLQPMNAYGLFDEYLEMI
                     LQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILE
                     GIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRIS
                     DFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLAPYGYTLQFWHVLAARLAFIIVF
                     EHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKNGKA
                     HHNEWP"
ORIGIN      
        1 cggtagtcta tgtcagcctg cagtttgccc atggctggaa ggcatcacag aacgtccatg
       61 gaattttcaa cctctaagag aaaagagaac tataattaga aactcagcat cacataaaga
      121 caccaagggt cagtatcctc ttactcctga cgggagaaag gaattggttc ttctactaag
      181 aaagtaacct taaacattct tccaaagtta aaaaaaatct ggaagtctca ctatgacctc
      241 tcttagtgtt tagcctcaga aaccactttc tggtccaatt taatcatcac aggcaaacac
      301 ggtttaatat gaatgccacc gaatggtttt agaaaaagag aaatactaaa agtgtagaat
      361 tatttttcat taaccatgga ggcctgggtt cctttctgtt ggcgtaaact gtggtatgtc
      421 actttagtga ttatagatta ttaatctctg ttcaccaaga gtaagcatgt cctgtcttaa
      481 atcgtgggtg atttaagagt cgtcaaagag aaacacaaac cgtccttagg aactcacatt
      541 gaacaacatc tctataaaac accacccaga aactcaatga agaaagaggg agggtcaaat
      601 tcccgaagag acctttaact cttttctgtc taaatttctc ccatgatgtg aaaagcccta
      661 ttcctgacaa tctcaacctg cacttctgtc atagacaggc acaggtccac agtgccattt
      721 tcgaactggt ggtgaccttg tggagggtcc tgtcagagct gtctgatgtg agaggagtca
      781 ctagccacca ctcacattcc ctctggcttc ctgcagagag agggtggaaa actgccttgg
      841 gaacttgctg agtggcccat ggaactatgg ggctttggga attaacaaac agcaaacaaa
      901 tattaagaga ccgggagtaa gcaagctgcc aatcctgcca aacttctgtt gctggcaggg
      961 agctgtcctg cagctccctg gtccgcctgt catctgcact ctcttgtcac actgacaaca
     1021 gccccctggt taggctgatt ggttgctggc aataactgat atggaatact gatgtgctta
     1081 ccggcagttc cttccactcc aaagaggctc cttccctaac ccaaacctcg ctttccgaag
     1141 cctagcctgc tgcccccgcc ccccacccca tgccgcccct gcaccggcgg ggaggaccag
     1201 tcctaggagc gatgctctga gattgtggtg aaattggtcc ccggctggct gctttcactc
     1261 cggctcggct cccttgctct ccggggagag tcctgttcca gacttctcgg ggttttacag
     1321 cacagacaac tgcatgcggg ctggagggga ggctgaaagg acttgtgtgt ggagggcttg
     1381 ttgcctccca tcactttgcc aaggttcgct gtgaatttcc ttctaccaca gacaccggag
     1441 gaaggatctc ttcttctgtt gactctttct atttttatgg tttaagttta tctattcatg
     1501 gggctgaaaa gcgcttgcaa atccatcaac ggcgaagtgt ggcaagccgc ccagggtcac
     1561 gacgtcgcct gcctgtggtc aggcattcct cactcccacc aggcagacgg tcaataaaaa
     1621 tggaggccag ctcttctgga atcactaatg gaaaaaacaa agttttccat gcagtggcca
     1681 aggatgtcaa catttttttt gatgaactag aggctgtcaa cagcccgtgc aaagacgatg
     1741 attctctcct tcaccctgga aatctgacca gtacgtcgga ggacaccagc agactggaag
     1801 cagggggaga gaaagtgcga gaacgaaaca aatcaaatgg actttacttt agagacggaa
     1861 aatgtcgaat tgactacatc cttgtgtaca gaaaatccaa ccctcagact gaaaagagag
     1921 aagtgtttga aagaaatatt agagcagaag gattacagat ggagaaagag tcctctctaa
     1981 taaatagtga cattatcttt gtgaagttgc atgccccatg ggaagtcctt ggaagatatg
     2041 cagagcaaat gaatgtacgg atgcctttca ggagaaaaat ctattacctg ccccgccggt
     2101 acaagttcat gagcaggatc gataaacaaa taagcaggtt ccggagatgg ttacctaaga
     2161 agccaatgag gctggacaag gagacactgc cagacctgga agagaatgac tgctacactg
     2221 cccctttcag ccagcaaagg attcatcact tcatcataca caacaaagac actttcttca
     2281 acaacgccac cagaagcaga atcgtgcatc atattttaca aaggataaag tacgaggaag
     2341 gaaaaaacaa aatcggtctg aaccgcttgc ttaccaatgg ctcctatgaa gctgcttttc
     2401 ccctgcatga gggaagttat agaagtaaaa actccattaa aacccatgga gctgtaaacc
     2461 accggcatct actgtatgag tgctgggcct cctggagtgt gtggtacaag taccagcctt
     2521 tggatcttgt aaggcggtat tttggagaga agattggact gtattttgcc tggctgggat
     2581 ggtacacagg catgctcttc ccggcagcct tcattggctt gtttgtcttc ttgtatggag
     2641 tcaccactct ggatcactgc caagtcagta aagaagtctg ccaagcaaca gatatcatca
     2701 tgtgtcctgt gtgtgacaag tactgtccat tcatgaggct atcagacagc tgcgtctatg
     2761 ccaaggtgac ccaccttttt gacaacgggg ctactgtgtt ctttgctgtg ttcatggcag
     2821 tctgggccac tgttttcctg gagttctgga agagacgccg agcggtgatc gcttatgact
     2881 gggatctgat tgactgggaa gaagaggagg aagaaatacg gccccagttt gaagccaagt
     2941 attccaagaa agagcggatg aatcccattt cgggaaagcc agaaccttat caggcattta
     3001 ctgataaatg cagcagactt atcgtttctg catcgggaat attcttcatg atctgtgtgg
     3061 tgatcgcggc cgtgttcggg atcgtcattt accgggtggt gaccgtgagc actttcgccg
     3121 cctttaagtg ggcgttaatc aggaacaact ctcaggtcgc gaccacaggg actgcagtgt
     3181 gcatcaactt ctgtatcatt atgctgctga acgtgctcta tgaaaaagtc gcactccttc
     3241 tgacaaatct ggaacagcct cgcacagaat ccgagtggga gaacagcttt accttgaaaa
     3301 tgttcctttt tcagttcgtc aatctgaaca gctctacttt ttacatcgca ttcttccttg
     3361 gaagatttac aggacaccca ggtgcctact tgagattgat aaacaggtgg aggctagaag
     3421 agtgccaccc tagtggatgc cttattgatc tctgcatgca aatgggtatt ataatggtgc
     3481 taaagcagac ctggaataat ttcatggaac ttggctaccc gttaattcag aattggtgga
     3541 ctagaagaaa agtccgacaa gaacatggga ctgaaaggaa aataaatttc ccacagtggg
     3601 aaaaggacta caatcttcag ccgatgaatg cctatggact cttcgatgaa tacctggaaa
     3661 tgatccttca gttcggattc acaactatct ttgtggcagc ttttcctcta gcaccgcttc
     3721 tggccttact gaataacatc attgaaatcc gacttgatgc ttacaagttt gtgactcagt
     3781 ggagaaggcc tctggcttcg agggccaagg acataggaat ttggtatgga attctcgaag
     3841 gcatcgggat tctctctgtt attacgaacg cgtttgtcat agcaataaca tccgacttca
     3901 tccctcgctt agtatatgct tataaatatg gaccgtgtgc aggccaagga gaagctgggc
     3961 agaagtgcat ggttggctat gtaaatgcca gcttgtccgt gttccgaatt tctgactttg
     4021 aaaaccggtc tgagccagag tctgatggca gtgagttctc aggaactcct ctgaagtact
     4081 gcagatatcg ggactaccgg gacccgcctc attctttggc tccctatggc tacacactgc
     4141 agttctggca tgtcctcgca gctcggctgg ctttcatcat tgtgtttgag cacctcgtgt
     4201 tttgtataaa gcacctcatt tcctatctga taccagacct cccgaaagat ctaagggacc
     4261 ggatgaggag agagaagtac ttgatccagg agatgatgta tgaggctgaa ctggaacgcc
     4321 tccagaaaga acggaaggag aggaagaaga atggaaaagc acatcacaat gagtggccgt
     4381 ga
//
