LOCUS       NM_001014219            2776 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ankyrin repeat and zinc finger peptidyl tRNA
            hydrolase 1 (Ankzf1), mRNA.
ACCESSION   NM_001014219 XM_343595
VERSION     NM_001014219.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2776)
  AUTHORS   van Haaften-Visser,D.Y., Harakalova,M., Mocholi,E., van
            Montfrans,J.M., Elkadri,A., Rieter,E., Fiedler,K., van
            Hasselt,P.M., Triffaux,E.M.M., van Haelst,M.M., Nijman,I.J.,
            Kloosterman,W.P., Nieuwenhuis,E.E.S., Muise,A.M., Cuppen,E.,
            Houwen,R.H.J. and Coffer,P.J.
  TITLE     Ankyrin repeat and zinc-finger domain-containing 1 mutations are
            associated with infantile-onset inflammatory bowel disease
  JOURNAL   J Biol Chem 292 (19), 7904-7920 (2017)
   PUBMED   28302725
REFERENCE   2  (bases 1 to 2776)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Mar 3, 2021 this sequence version replaced NM_001014219.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081973.1, SRR26360190.1633140.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-529               JAXUCZ010000009.1  84136862-84137390
            530-636             JAXUCZ010000009.1  84138946-84139052
            637-739             JAXUCZ010000009.1  84139269-84139371
            740-933             JAXUCZ010000009.1  84139494-84139687
            934-1046            JAXUCZ010000009.1  84140038-84140150
            1047-1194           JAXUCZ010000009.1  84140239-84140386
            1195-1423           JAXUCZ010000009.1  84140585-84140813
            1424-1579           JAXUCZ010000009.1  84140956-84141111
            1580-2060           JAXUCZ010000009.1  84142106-84142586
            2061-2172           JAXUCZ010000009.1  84142719-84142830
            2173-2340           JAXUCZ010000009.1  84142930-84143097
            2341-2426           JAXUCZ010000009.1  84143229-84143314
            2427-2776           JAXUCZ010000009.1  84143481-84143830
FEATURES             Location/Qualifiers
     source          1..2776
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q33"
     gene            1..2776
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /note="ankyrin repeat and zinc finger peptidyl tRNA
                     hydrolase 1"
                     /db_xref="GeneID:363255"
                     /db_xref="RGD:1359242"
     exon            1..529
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
     CDS             304..2550
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /note="ankyrin repeat and zinc finger domain-containing
                     protein 1; ankyrin repeat containing protein RGD1359242;
                     ankyrin repeat and zinc finger domain containing 1"
                     /codon_start=1
                     /product="tRNA endonuclease ANKZF1"
                     /protein_id="NP_001014241.2"
                     /db_xref="GeneID:363255"
                     /db_xref="RGD:1359242"
                     /translation="MTRPAADAVVESRSGELFLPSVSSSAMLPAPRAAPVPASVSLLT
                     LNGEAPLVRGLSLVSQAPGEALAWAPRTSCPGENTSSGRKVSPCSLDISDKLFCSACD
                     QVFQNHQEQREHYKLDWHRFNLKQRLKNKPLLSASDFERQSSRGDLSSISGSEDSDSA
                     SEEDLLTLDEERAESEKPNRPPGFYPHRVLFRNAQGQFLYAYRCVLGPHQIPPEKAEL
                     LLQNLQNGGPRHYVVLMAAAGHFAGAIFQGREVVAHKTFHRYTVRAKRGTAQGLQDAQ
                     GRASRSAGANLRRYNEAMLYKDVRDLLAGPTWSKALGEAETILLHAPRSGRSLFFGGQ
                     GAPLQRSDFRLWDIPLTTRRPTFGELQRVLHKLTTLQVYDEDPREMVRFHSPETHCKP
                     VREERKRDTEKEKTKVPSDANKALGQDEEPLKQGSESQEEDGSEVELELVELTLGTLD
                     LREFEVLPKRRKKRKKKERSQKQQCGAHGPLLQQPQDEPFSQPTQVVATPLDTLVDEA
                     KAPGQPELWDMLLAACRAGEVEVLKLQLATGPVDPGVMSLLSAPLGSGGFTLLHAAAA
                     AGRGLVVRLLLEAGADPTVHDSRARPPYTVAADRSTRNEFRRFMEKNLDAYDYSKARV
                     PGPLTQEMEARQATRKKEQKAARRQREQQQRKQREQEEQEQEERRRFAALSDREKRAL
                     AAERRLAAQLGAPSPPVPDSAVVNAGRCWSCGVSLQGLIPFHYLDFSFCSTRCLRDHR
                     SQAGRPSS"
     exon            530..636
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
     exon            637..739
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
     exon            740..933
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1046
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1194
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
     exon            1195..1423
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1579
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
     exon            1580..2060
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
     exon            2061..2172
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
     exon            2173..2340
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
     exon            2341..2426
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
     exon            2427..2776
                     /gene="Ankzf1"
                     /gene_synonym="RGD1359242"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggctacggg cgcggcagtg tgtccccttc gcctctccgt agctaccgga ttgttgtgtg
       61 ttgcagaaat ccagttttcg aacggtggac ttgcgtgtgg ctctgctctt gggacattag
      121 cgggtcgagt ggcgaagttc ggtgtccgtg ctagtagatc ggttgggtag cctctgactg
      181 gtagactcct ggacccgatt tgggtctcgg tgctttccat ttcactcctg aagatcctca
      241 cgtatttccc gcagaactga gttgtggtag cgggtgaagg ccgaggggcc tttctgtgtg
      301 gggatgacca ggccggctgc cgacgcagta gtagaatctc gctctggaga gctgtttctg
      361 ccctccgttt cttcttcagc catgttgcca gctccacgtg cagccccagt ccctgcctcg
      421 gtttccctgt tgaccctcaa cggggaagct ccacttgttc ggggcctgag cctggtgagc
      481 caagctcccg gggaggctct ggcctgggcg ccgcgtactt cctgtccagg agagaacaca
      541 agctcaggga gaaaagtatc tccatgttct ctggatattt cagataaatt attttgttca
      601 gcctgtgacc aggtcttcca gaaccaccag gaacagagag aacattataa acttgattgg
      661 catcgcttta acctaaaaca acgtctcaag aataagcctc tcctatctgc ttcagacttt
      721 gaaaggcaaa gctccagagg agatctttcc agcatctcag gatcagaaga ctcagactca
      781 gccagtgaag aggacttgct gacactggat gaggagaggg ctgaatctga aaaacccaac
      841 cgaccccctg gattctaccc acatcgggtc cttttcagaa acgcccaggg ccagtttctt
      901 tatgcctatc gttgtgtcct aggccctcac cagattcctc cagaaaaggc agaattgctg
      961 ctacaaaacc tgcaaaatgg aggtcccaga cactacgtgg tgctcatggc tgcagctggg
     1021 cattttgctg gtgccatttt ccaaggaaga gaagtggtgg cacacaaaac ctttcaccgt
     1081 tacactgtgc gggccaagcg gggcacagcc cagggccttc aggatgccca gggtagggca
     1141 tcccgctctg ctggagccaa cttgaggcgt tacaatgaag ccatgctcta caaggatgtt
     1201 cgtgacctgc tggcagggcc aacctggtcc aaagcactag gagaggcaga aacaatactg
     1261 ctgcatgccc cacgctctgg ccggtccttg ttctttggag gccaaggggc acccctacaa
     1321 aggagtgatt tccgactttg ggatatccct ctcaccaccc gcagacccac ttttggagag
     1381 cttcagcgtg tactccataa gctgaccacc ttgcaggtgt atgatgaaga ccctcgagaa
     1441 atggtcagat ttcactctcc tgagacacac tgcaaaccag tgagagaaga gaggaaaagg
     1501 gatactgaga aagaaaaaac aaaggtccct agtgatgcaa ataaggcact tgggcaggat
     1561 gaagaaccac tcaaacaagg ttccgagtct caggaagaag atggctccga agtagagttg
     1621 gagctagtag agctgacact ggggaccctg gatcttcgtg aatttgaagt attgcccaag
     1681 cggaggaaga agaggaaaaa gaaggagaga agtcaaaagc agcaatgtgg ggcacatggg
     1741 ccccttcttc agcaacctca agatgagcca ttctcacagc caacccaagt ggttgcaacc
     1801 ccattggaca ctttggtcga tgaggccaaa gcccctggtc aaccagagct ctgggatatg
     1861 cttctagctg cttgtcgtgc tggggaagtt gaggtgctaa agctgcagct agccactggg
     1921 cctgtagacc ctggagttat gtccctactc agtgcccctt tgggctctgg tggctttact
     1981 ctcctgcatg cagcagccgc agctggaaga ggcttagtag ttcgtttgct gttggaggca
     2041 ggtgctgacc ccactgtgca tgactctagg gctcggccac cttatactgt agcagctgac
     2101 agatcaacgc gtaatgaatt ccggaggttc atggagaaga atcttgatgc ttatgattac
     2161 agcaaggctc gggtgccagg gccattgact caagaaatgg aggcccggca ggctacaagg
     2221 aaaaaggagc agaaggcagc tcgacggcag cgggagcaac agcagcggaa gcagagggaa
     2281 caggaagaac aggagcaaga ggagcgaagg cggtttgctg ccctcagtga ccgagagaag
     2341 agagctctgg ctgcagagcg ccgacttgct gcccagttgg gagcccctag ccctccagtt
     2401 cctgactctg cagttgtcaa tgctgggcgc tgctggagtt gtggtgtgtc cctccaaggc
     2461 ctcattccct ttcactacct cgatttctct ttctgctcca cacgttgcct tcgagaccat
     2521 cgcagtcagg cagggaggcc gtcatcatga tttcttatag ccacctgggg ccaactctgg
     2581 gtcccaagag gacacatcca gacctagagc tctcttcctc cttgtgaagc ttgacattat
     2641 ttggaagatg ggcagtgaag gacactcagg aactggggca aagacagggc cccaaaggtg
     2701 tgtggggcca gtactgtctt tggaatttta atcacaataa agtttggcaa gaaaactgtg
     2761 tatgtactta cactca
//
