LOCUS       NM_001009676            2420 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus ankyrin repeat and sterile alpha motif domain
            containing 3 (Anks3), transcript variant 1, mRNA.
ACCESSION   NM_001009676 XM_220159
VERSION     NM_001009676.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2420)
  AUTHORS   Nakajima,Y., Kiyonari,H., Mukumoto,Y. and Yokoyama,T.
  TITLE     The Inv compartment of renal cilia is an intraciliary
            signal-activating center to phosphorylate ANKS6
  JOURNAL   Kidney Int 93 (5), 1108-1117 (2018)
   PUBMED   29395339
REFERENCE   2  (bases 1 to 2420)
  AUTHORS   Delestre,L., Bakey,Z., Prado,C., Hoffmann,S., Bihoreau,M.T.,
            Lelongt,B. and Gauguier,D.
  TITLE     ANKS3 Co-Localises with ANKS6 in Mouse Renal Cilia and Is
            Associated with Vasopressin Signaling and Apoptosis In Vivo in Mice
  JOURNAL   PLoS One 10 (9), e0136781 (2015)
   PUBMED   26327442
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2420)
  AUTHORS   Ramachandran,H., Engel,C., Muller,B., Dengjel,J., Walz,G. and
            Yakulov,T.A.
  TITLE     Anks3 alters the sub-cellular localization of the Nek7 kinase
  JOURNAL   Biochem Biophys Res Commun 464 (3), 901-907 (2015)
   PUBMED   26188091
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 20, 2022 this sequence version replaced NM_001009676.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087062.1, SRR26360194.1716962.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                JAXUCZ010000010.1  11121561-11121627
            68-239              JAXUCZ010000010.1  11124696-11124867
            240-438             JAXUCZ010000010.1  11127081-11127279
            439-560             JAXUCZ010000010.1  11127467-11127588
            561-642             JAXUCZ010000010.1  11129340-11129421
            643-778             JAXUCZ010000010.1  11131294-11131429
            779-934             JAXUCZ010000010.1  11134370-11134525
            935-1072            JAXUCZ010000010.1  11135805-11135942
            1073-1182           JAXUCZ010000010.1  11136411-11136520
            1183-1350           JAXUCZ010000010.1  11136733-11136900
            1351-1475           JAXUCZ010000010.1  11137909-11138033
            1476-1617           JAXUCZ010000010.1  11140001-11140142
            1618-1790           JAXUCZ010000010.1  11140446-11140618
            1791-1876           JAXUCZ010000010.1  11140914-11140999
            1877-1960           JAXUCZ010000010.1  11141387-11141470
            1961-2044           JAXUCZ010000010.1  11141699-11141782
            2045-2420           JAXUCZ010000010.1  11141886-11142261
FEATURES             Location/Qualifiers
     source          1..2420
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..2420
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /note="ankyrin repeat and sterile alpha motif domain
                     containing 3"
                     /db_xref="GeneID:302937"
                     /db_xref="RGD:1305833"
     exon            1..67
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            68..239
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..2061
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ankyrin repeat and SAM domain-containing protein 3"
                     /codon_start=1
                     /product="ankyrin repeat and SAM domain-containing protein
                     3 isoform 1"
                     /protein_id="NP_001009676.1"
                     /db_xref="GeneID:302937"
                     /db_xref="RGD:1305833"
                     /translation="MSELSDEASEPELLNRSLSMWHGLGAQVSREELDVPLDLHTAAS
                     IGQYEVVKECVQRRELDLNKKNGGGWTPLMYASYIGHDTIVHLLLEAGVSVNVPTPEG
                     QTPLMLASSCGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQQMVKFLLESGAN
                     ANVREPVYGFTPLMEAAAAGHEIIVQYFLNHGVKVDTRDHSGATARMLAKQYGHMKIV
                     ALMETHSPVLPKSLYRSSENYEDLSSSDESWPVPQRQRPCRKKGLSIHEGPRALARIT
                     ATGLGGKTPDSYEQVPPRGYVTFTSSDENTMEGEGLCYRDVTSPINERDVESSSSSSR
                     EEPTFCASLGPVWRSSSSDGLARAQGLSSEASIESNEDSDHARKSSVRKQTRTYLKNK
                     SRHNNSDGHWPSSTGTARTPGSEPQAEKSPYSGPQDLATLLEQIGCLKYLQVFEEQDV
                     DLRIFLTLTESDLKEIGITLFGPKRKMTSAIARWHSSARPPSDALELAYADRLEAEMQ
                     ELAIQLHKCCEEAEALRGQVSQEQELRAVVESCLLEQDSARKDIHAQLQEAQTLAQDA
                     ALVLDQLRACQAELSARLKQHHSPSEATQNPPFLPADSKGWPIPLQALSLPELSGALE
                     DRVHEMGIMLRNAEPGETTDAEWEEMEGTIARRDDSDVG"
     exon            240..438
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            439..560
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            561..642
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            643..778
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            779..934
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            935..1072
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            1073..1182
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1350
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1475
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..1617
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            1618..1790
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            1791..1876
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1960
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            1961..2044
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
     exon            2045..2420
                     /gene="Anks3"
                     /gene_synonym="RGD1305833"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctgttggcc ggtgagggag cgtgcagctg ctgctggagg gtggcgcggg aacctgaggc
       61 cttgcagcca tgtctgagct cagcgatgaa gccagcgagc cggagcttct gaaccgcagc
      121 ttgtccatgt ggcatggact tggtgcacag gtcagcagag aggagctgga tgtccccttg
      181 gatcttcaca cagctgcctc cattggccag tatgaggtgg tgaaggagtg tgtgcagcgg
      241 agagagttag atttgaataa gaagaatggt ggtggctgga ctccgctgat gtatgcctcc
      301 tacattggac acgataccat tgttcacttg ctgctcgagg caggtgtgag tgtgaatgtg
      361 ccaaccccag aaggacagac tccactgatg ctggcctcca gctgtggtaa cgagagcatc
      421 gcctacttcc tgctccagca aggtgcagag cttgagatga aagacatcca gggctggact
      481 gcactctttc actgcaccag tgccggccac cagcagatgg tcaagtttct tctggagagt
      541 ggagccaatg ccaacgtgag ggaacctgta tatggattca ctcctttgat ggaagcagct
      601 gccgctggcc atgagataat tgtgcagtat tttctgaatc atggagtcaa agtggacaca
      661 agagaccaca gtggagccac agcccggatg ctagccaagc agtatggtca catgaagatt
      721 gtggctttga tggaaactca ctcacctgta ctgcccaaga gcctctaccg tagctcagaa
      781 aactatgaag acctgagctc ttcagatgag tcctggcctg ttcctcagcg ccagaggccc
      841 tgtcgaaaga agggcctgag tatccacgag gggcctcgcg ccctggccag gatcacagct
      901 actggactgg gaggcaagac tccggacagc tatgagcaag ttcctccacg gggctatgtg
      961 accttcacca gcagtgatga gaacaccatg gaaggcgagg gcctctgcta ccgagatgtc
     1021 acttccccca tcaatgaacg cgatgtggag agcagtagca gcagcagccg ggaggaaccc
     1081 actttctgtg ccagtcttgg gcctgtgtgg aggagcagca gcagtgatgg cctagcaaga
     1141 gcccagggtc tcagcagtga agcctccata gagagcaatg aggattctga tcacgcccgc
     1201 aaaagctcgg ttcgtaaaca aaccaggact tatttgaaga ataagagtcg tcacaacaac
     1261 agtgatggtc actggccttc tagcacaggg actgctcgca ctccagggtc tgaaccccaa
     1321 gctgagaagt ccccttactc aggaccccag gatcttgcca cactgttgga acagatcggc
     1381 tgtctaaagt acctgcaagt gtttgaggag caggatgtag acctgcgtat ctttctgacc
     1441 ctcactgaaa gcgacctgaa ggaaattggc atcacgttgt ttgggcccaa aaggaaaatg
     1501 acctctgcca ttgcccgatg gcacagtagt gcccgcccac ctagtgatgc cctagagctg
     1561 gcctatgctg accggctgga ggcggagatg caggagcttg ccatccagct gcacaaatgc
     1621 tgtgaggagg cagaggctct gcgtggccaa gtctcccagg agcaggaatt gcgggctgta
     1681 gtagagagct gcctcctgga gcaggatagt gcccgaaagg acatccatgc ccagctgcag
     1741 gaggcccaaa ccctggccca ggatgctgct cttgtcctag accagctgcg ggcctgtcaa
     1801 gctgagttgt cagctcgatt gaagcagcac cactccccca gcgaagctac ccaaaaccca
     1861 ccctttctcc cagcagattc caaaggctgg cctattcccc tgcaggcctt gagcctccct
     1921 gagttgtcag gagccctgga agaccgtgtc catgagatgg gcattatgct ccgtaacgca
     1981 gagcctggag aaactacaga tgctgaatgg gaagaaatgg agggaaccat agccaggagg
     2041 gacgattctg acgttgggtg acgaatccac cctgaagtta tgtgccacgc aagacagggc
     2101 agtgagcaga tggctgcggc agcccaggga atagaagacc agcccaggga gcagcttgtg
     2161 gacaggagga caggacttca gtcctcacta gggcagcttg ggccagccct gagacaggat
     2221 gaagggccta gcacccagat tctggtggag aggcccatgc tggtaggcag aggcagcttt
     2281 ggctcagacc aggcagggcc gtatggagag gctaagtcct gcacatgtag gggccacact
     2341 gaagtctgat tttacagtcg aagtctgggg tgcctagaaa atgtactctt tgaaaataaa
     2401 attagacgca agttggtggg
//
