LOCUS       NM_001420997            2287 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus angiopoietin like 7 (Angptl7), mRNA.
ACCESSION   NM_001420997 XM_006239424
VERSION     NM_001420997.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2287)
  AUTHORS   Yamamoto,A., Huang,Y., Krajina,B.A., McBirney,M., Doak,A.E., Qu,S.,
            Wang,C.L., Haffner,M.C. and Cheung,K.J.
  TITLE     Metastasis from the tumor interior and necrotic core formation are
            regulated by breast cancer-derived angiopoietin-like 7
  JOURNAL   Proc Natl Acad Sci U S A 120 (10), e2214888120 (2023)
   PUBMED   36853945
  REMARK    GeneRIF: Metastasis from the tumor interior and necrotic core
            formation are regulated by breast cancer-derived angiopoietin-like
            7.
REFERENCE   2  (bases 1 to 2287)
  AUTHORS   Toyono,T., Usui,T., Yokoo,S., Taketani,Y., Nakagawa,S., Kuroda,M.,
            Yamagami,S. and Amano,S.
  TITLE     Angiopoietin-like 7 is an anti-angiogenic protein required to
            prevent vascularization of the cornea
  JOURNAL   PLoS One 10 (1), e0116838 (2015)
   PUBMED   25622036
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2287)
  AUTHORS   Comes,N., Buie,L.K. and Borras,T.
  TITLE     Evidence for a role of angiopoietin-like 7 (ANGPTL7) in
            extracellular matrix formation of the human trabecular meshwork:
            implications for glaucoma
  JOURNAL   Genes Cells 16 (2), 243-259 (2011)
   PUBMED   21199193
REFERENCE   4  (bases 1 to 2287)
  AUTHORS   Peek,R., Kammerer,R.A., Frank,S., Otte-Holler,I. and Westphal,J.R.
  TITLE     The angiopoietin-like factor cornea-derived transcript 6 is a
            putative morphogen for human cornea
  JOURNAL   J Biol Chem 277 (1), 686-693 (2002)
   PUBMED   11682471
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On May 10, 2023 this sequence version replaced XM_006239424.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.1832426.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676807 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-540               JAXUCZ010000005.1  164219869-164220408 c
            541-641             JAXUCZ010000005.1  164218126-164218226 c
            642-836             JAXUCZ010000005.1  164217420-164217614 c
            837-1035            JAXUCZ010000005.1  164216638-164216836 c
            1036-2287           JAXUCZ010000005.1  164215223-164216474 c
FEATURES             Location/Qualifiers
     source          1..2287
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2287
                     /gene="Angptl7"
                     /note="angiopoietin like 7"
                     /db_xref="GeneID:102552055"
                     /db_xref="RGD:7553363"
     exon            1..540
                     /gene="Angptl7"
                     /inference="alignment:Splign:2.1.0"
     CDS             192..1205
                     /gene="Angptl7"
                     /note="angiopoietin-related protein 7;
                     angiopoietin-related protein 7-like"
                     /codon_start=1
                     /product="angiopoietin-related protein 7 precursor"
                     /protein_id="NP_001407926.1"
                     /db_xref="GeneID:102552055"
                     /db_xref="RGD:7553363"
                     /translation="MLRTTWLCILLVASVSRPVWLQKPHKRKTQLKAAGCCEEMRELK
                     AQVANLSSLLGELSRKQESDWVSVVMQVMELESSSKRMESRLTTAESKYSEMNNQIDI
                     MQLQAAQTVTQTSADAIYDCSSLYQKNYRISGVYKLPPDEFLGSPELEVFCDMETSGG
                     GWTIIQRRKSGLVSFYQDWKQYKQGFGSIRGDFWLGNEHIHRLTRQPTRLRVELEDWE
                     GNARYAEYSYFALGNELNSYRLFLGNYSGNVGKDALLYHNNTVFSTKDKDNDNCLDKC
                     AQLRKGGYWYNCCTDSNLNGVYYRLGEHRKHMDGISWYGWHGANYSLKRVEMKIRPEA
                     FTP"
     exon            541..641
                     /gene="Angptl7"
                     /inference="alignment:Splign:2.1.0"
     exon            642..836
                     /gene="Angptl7"
                     /inference="alignment:Splign:2.1.0"
     exon            837..1035
                     /gene="Angptl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..2287
                     /gene="Angptl7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agacttggga aggaaaagtg tttaaatacc caccaagctc cgtttcagaa actccagctt
       61 taagaaaggc acacagagga aggagaccac gaggaaggaa gaaaactgcc cttgtgagtc
      121 aaacactaag cttcctagtt ctgctgaata cagactctag gaggaagacc tgccccagag
      181 gcctgcacac aatgctgagg accacctggc tatgcattct cctggtagcc tctgtcagtc
      241 gccccgtgtg gctgcagaag cctcataaac gcaagacaca gctcaaagca gccggctgct
      301 gtgaggagat gagggagctc aaggcccagg tcgccaacct cagcagtctg ctgggtgagc
      361 tgagcaggaa gcaggagagc gactgggtca gtgtggtcat gcaggtgatg gagctggaga
      421 gcagcagcaa gcgcatggag tctcggctca ccactgccga gagcaagtac tctgagatga
      481 acaaccagat cgacatcatg cagttacagg ctgcacagac cgtcacacag acctcggcag
      541 atgccatcta cgactgttcc tccctgtacc agaagaacta ccgaatctct ggagtgtaca
      601 agcttcctcc agatgagttc ctgggcagcc ctgagttaga ggtgttctgt gacatggaaa
      661 cttcaggagg aggctggacc atcatccaga ggcgcaagag tggcctagtc tccttctacc
      721 aagactggaa acagtataag caagggtttg gcagcattcg aggcgacttc tggctaggga
      781 atgaacatat tcaccggctt accaggcagc caacaaggct tcgtgtggag ctggaggact
      841 gggagggcaa cgcacgctac gcagagtaca gctactttgc gttgggcaat gaactgaaca
      901 gctaccgcct cttcctgggg aactacagtg gcaacgtggg gaaggacgct ctcctctatc
      961 ataacaacac cgtcttcagc accaaggaca aggacaatga caactgcttg gacaagtgtg
     1021 cacagctccg aaaaggtggc tactggtaca actgctgcac agactccaac ctcaatgggg
     1081 tgtactaccg cctgggggag caccggaagc acatggatgg catcagctgg tatggctggc
     1141 atggagccaa ctattccctc aaacgggtgg agatgaagat ccgtccagaa gccttcacgc
     1201 cctaggagaa ggttgctgca gagctatgtg aggcggaggc tgaggaggga gagcaggatg
     1261 ggaagagggt ggacaaaagg taggaagggg acagtttatc atccaggagc gtgacacaac
     1321 ttcacctgtg cacacaagag cacatgcaca cacaacagaa ccacacagac caaacagtgc
     1381 acattagcag atggcaccag gccagtaggt gccatggtgc ctcaggggag gactgagtgg
     1441 gcccacagag cagaagctca tcctccacac ccttagctgt gctcaacagt gaccctgagg
     1501 tcacgaaacc tgtttcccct acctgaggct cagatgacat gagggaaaag aaaaataaaa
     1561 ggaactgttg tgaccctccg tggagaggcc atgaaaaatg aaagcagatg gtggagaagg
     1621 ggcttcccct tcttaggtcc catgacactt ccttgtgtct ataggatttg ttttgttttc
     1681 ctttgtgaca cagggtctct ctacacagct cttgctgtcc tggaacttac tatgtagacc
     1741 aggctggcct tgaacttaaa gagatctgct tctgcttcca aagtgcaggg attaaaaggc
     1801 ctgcaccacc ataaccagca tataggaatt ttaagacaca aaaaatgtgg agctgaagac
     1861 cagctgtcca gattggactt gcttcaaggc atctccaggg tcttagttag gccttgcagg
     1921 cagaatcctg ggggagagaa cagtactata aagcacactg tgggcctaac gtgggagaga
     1981 gagaggacca gcggggaggc gagcacagtc tctgggtgat cacaacactg ccttcactct
     2041 ccatcaaaaa acattctttt tttttttttt tttttttttt tttttttttt ttttacttat
     2101 tctgtaagaa acagactcaa acagatcccc tttaacaaaa atgcctggaa aataagggta
     2161 catggcgctg tggtttaaaa cttgtgctat atagagaagc atcttccttg taaaaataaa
     2221 atattgtagt tttcattttg aatattcaaa atatcttttt cttttacaat aaatactatc
     2281 aaaattt
//
