LOCUS       NM_001106702            1570 bp    mRNA    linear   ROD 06-JUN-2023
DEFINITION  Rattus norvegicus angiopoietin-like 6 (Angptl6), mRNA.
ACCESSION   NM_001106702 XM_001077150 XM_216613
VERSION     NM_001106702.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1570)
  AUTHORS   Valencia-Martinez A, Schaefer-Graf U, Amusquivar E, Herrera E and
            Ortega-Senovilla H.
  TITLE     Relationship of ANGPTL6 With Neonatal Glucose Homeostasis and Fat
            Mass Is Disrupted in Gestational Diabetic Pregnancies
  JOURNAL   J Clin Endocrinol Metab 107 (10), e4078-e4085 (2022)
   PUBMED   35876300
REFERENCE   2  (bases 1 to 1570)
  AUTHORS   Oike Y, Ito Y, Maekawa H, Morisada T, Kubota Y, Akao M, Urano T,
            Yasunaga K and Suda T.
  TITLE     Angiopoietin-related growth factor (AGF) promotes angiogenesis
  JOURNAL   Blood 103 (10), 3760-3765 (2004)
   PUBMED   14764539
REFERENCE   3  (bases 1 to 1570)
  AUTHORS   Oike Y, Yasunaga K, Ito Y, Matsumoto S, Maekawa H, Morisada T, Arai
            F, Nakagata N, Takeya M, Masuho Y and Suda T.
  TITLE     Angiopoietin-related growth factor (AGF) promotes epidermal
            proliferation, remodeling, and regeneration
  JOURNAL   Proc Natl Acad Sci U S A 100 (16), 9494-9499 (2003)
   PUBMED   12871997
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473993.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001077150.1, XM_216613.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166828.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1570
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..1570
                     /gene="Angptl6"
                     /note="angiopoietin-like 6"
                     /db_xref="GeneID:298698"
                     /db_xref="RGD:1311141"
     exon            1..110
                     /gene="Angptl6"
                     /inference="alignment:Splign:2.1.0"
     exon            111..665
                     /gene="Angptl6"
                     /inference="alignment:Splign:2.1.0"
     CDS             120..1493
                     /gene="Angptl6"
                     /note="angiopoietin-related protein 6"
                     /codon_start=1
                     /product="angiopoietin-related protein 6 precursor"
                     /protein_id="NP_001100172.1"
                     /db_xref="GeneID:298698"
                     /db_xref="RGD:1311141"
                     /translation="MGTAVLRKLQLVLLLGAWKALGDAARCRVTLVLSPQMATSAVCR
                     SSEASQDSELATLRMRLGRHEELLRALQRRAAEGGALAGEVRALREHSLTLNTRLGQL
                     RAQLQQEAGAEPDLGAEPAAALGLLAERALGAEAEARRTTARLQQLEEQLREHAQLMS
                     QHSSLLGRLQRACASPERGQQQVLPLPLVPLVPLSLVGSASNTSRRLDQIPEHQREQS
                     LRQQGPPSSPLPTGHVAVPTRPVGPWRDCAEAQGAGHWQSGVYELRLGRRVVPVWCEQ
                     QQEGGGWTVIQRRQDGSVNFFTNWQHYKVGFGRPDGEYWLGLEPVHQVTSRGDHELLI
                     LLKDWGGRGARAHYDSFSLEPESDHYRLRLGQYHGDAGDSLSWHSDKPFNTVDRDRDS
                     YSGNCALYHRGGWWYHACAHSNLNGVWYHGGHYRSRYQDGVYWAEFRGGAYSLKKAAM
                     LTRLVRL"
     exon            666..843
                     /gene="Angptl6"
                     /inference="alignment:Splign:2.1.0"
     exon            844..1031
                     /gene="Angptl6"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1302
                     /gene="Angptl6"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1570
                     /gene="Angptl6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcccagtcc tccatcctgg tcctctatcc cggtccttca ggctttactc cgattttgtg
       61 ggcttgcggc aaacctcact ggcgccagca cccgcgccgg gccgttggag gtggcggcca
      121 tggggactgc tgtgctgcgc aagctgcagc tggtgctcct gctgggcgct tggaaggcgc
      181 ttggagatgc cgcgcggtgc cgcgtcaccc ttgttctgtc cccgcagatg gcgactagcg
      241 cggtctgcag gagctcagaa gcttcccaag acagcgaact ggccacgctg cgcatgcgcc
      301 tgggccgtca cgaggagctg ctgcgcgcgc tgcaaaggcg tgcggccgag ggtggtgcgc
      361 tcgcgggcga ggtgcgcgcg ctgcgcgagc acagtctcac cctaaacaca cgtctgggcc
      421 agctgcgcgc gcaactgcag caggaggcgg gggcggagcc tgatctgggg gcggagcctg
      481 ctgccgcgct tggtttgcta gcagagcgcg cgctgggtgc ggaggccgaa gcgcgccgga
      541 cgaccgcgcg cctgcagcag ctggaggagc agctccgtga gcatgcgcag ctcatgagcc
      601 agcatagcag cctcctcggc cgcctgcaac gcgcgtgcgc gagcccggaa cggggccagc
      661 agcaggtcct gccactgccc ctggtgcctt tggttcctct gagtctagtg ggaagtgcca
      721 gcaacaccag ccggaggctg gaccaaattc cagagcacca gagagagcag agcttgagac
      781 agcaggggcc tccatcttct ccgctgccca cagggcacgt tgctgtcccc accaggccag
      841 tgggcccatg gagggattgt gcggaggccc agggggcagg tcactggcag agtggagtgt
      901 atgaactgcg gttgggccgt cgtgtggtac ccgtgtggtg tgaacagcag caggagggtg
      961 gaggctggac cgtcatccag aggcggcaag atggctctgt caacttcttc accaactggc
     1021 aacattacaa ggtgggcttt ggacgaccgg atggagaata ctggctgggc ttggaacccg
     1081 tgcatcaggt gactagccgc ggggaccacg agctgctgat actcttaaag gactgggggg
     1141 gccgtggggc acgcgcccac tatgacagct tctccttgga acccgagagt gaccactacc
     1201 ggctgcggct tggccagtac catggtgatg ctggagattc cctctcctgg cacagtgaca
     1261 aacctttcaa cactgtggat agggacagag actcatattc tggcaactgt gccctctacc
     1321 atcgtggggg ctggtggtac catgcctgcg cccactccaa cctcaatggt gtatggtatc
     1381 acggaggtca ttaccggagc cgataccagg acggggtcta ctgggccgag ttccgtggtg
     1441 gggcgtactc tctgaagaag gctgctatgc tgacccggct tgttcggttg tgactgtccc
     1501 atgagtaccc ccccaagggt gctcctatct ccttgagctg gtatcttata gcaacaggag
     1561 gtgtccattc
//
