LOCUS       NM_012718                824 bp    mRNA    linear   ROD 03-DEC-2024
DEFINITION  Rattus norvegicus androgen regulated protein (Andpro), mRNA.
ACCESSION   NM_012718
VERSION     NM_012718.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 824)
  AUTHORS   Pieragostino,D., Agnifili,L., Fasanella,V., D'Aguanno,S.,
            Mastropasqua,R., Di Ilio,C., Sacchetta,P., Urbani,A. and Del
            Boccio,P.
  TITLE     Shotgun proteomics reveals specific modulated protein patterns in
            tears of patients with primary open angle glaucoma naive to therapy
  JOURNAL   Mol Biosyst 9 (6), 1108-1116 (2013)
   PUBMED   23580065
REFERENCE   2  (bases 1 to 824)
  AUTHORS   Ma,L., Greenwood,J.A. and Schachner,M.
  TITLE     CRP1, a protein localized in filopodia of growth cones, is involved
            in dendritic growth
  JOURNAL   J Neurosci 31 (46), 16781-16791 (2011)
   PUBMED   22090504
  REMARK    GeneRIF: This study demonistrated that CRP1 is required for the
            dendritic growth induced by Ca(2) influx or CaMKIV. Together, these
            data are the first to demonstrate a role for CRP1 in dendritic
            growth.
REFERENCE   3  (bases 1 to 824)
  AUTHORS   Yohannes,E., Chang,J., Tar,M.T., Davies,K.P. and Chance,M.R.
  TITLE     Molecular targets for diabetes mellitus-associated erectile
            dysfunction
  JOURNAL   Mol Cell Proteomics 9 (3), 565-578 (2010)
   PUBMED   20007950
REFERENCE   4  (bases 1 to 824)
  AUTHORS   Fujimoto,N., Suzuki,T., Ohta,S. and Kitamura,S.
  TITLE     Identification of rat prostatic secreted proteins using mass
            spectrometric analysis and androgen-dependent mRNA expression
  JOURNAL   J Androl 30 (6), 669-678 (2009)
   PUBMED   19578134
REFERENCE   5  (bases 1 to 824)
  AUTHORS   Vanaken,H., Claessens,F., Vercaeren,I., Heyns,W., Peeters,B. and
            Rombauts,W.
  TITLE     Androgenic induction of cystatin-related protein and the C3
            component of prostatic binding protein in primary cultures from the
            rat lacrimal gland
  JOURNAL   Mol Cell Endocrinol 121 (2), 197-205 (1996)
   PUBMED   8892321
REFERENCE   6  (bases 1 to 824)
  AUTHORS   Ho,K.C., Marschke,K.B., Tan,J., Power,S.G., Wilson,E.M. and
            French,F.S.
  TITLE     A complex response element in intron 1 of the androgen-regulated
            20-kDa protein gene displays cell type-dependent androgen receptor
            specificity
  JOURNAL   J Biol Chem 268 (36), 27226-27235 (1993)
   PUBMED   8262963
REFERENCE   7  (bases 1 to 824)
  AUTHORS   Devos,A., De Clercq,N., Vercaeren,I., Heyns,W., Rombauts,W. and
            Peeters,B.
  TITLE     Structure of rat genes encoding androgen-regulated cystatin-related
            proteins (CRPs): a new member of the cystatin superfamily
  JOURNAL   Gene 125 (2), 159-167 (1993)
   PUBMED   8462870
REFERENCE   8  (bases 1 to 824)
  AUTHORS   Vercaeren,I., Winderickx,J., Devos,A., Peeters,B. and Heyns,W.
  TITLE     An effect of androgens on the length of the poly(A)-tail and
            alternative splicing cause size heterogeneity of the messenger
            ribonucleic acids encoding cystatin-related protein
  JOURNAL   Endocrinology 132 (3), 2496-2502 (1993)
   PUBMED   7679983
REFERENCE   9  (bases 1 to 824)
  AUTHORS   Winderickx,J., Hemschoote,K., De Clercq,N., Van Dijck,P.,
            Peeters,B., Rombauts,W., Verhoeven,G. and Heyns,W.
  TITLE     Tissue-specific expression and androgen regulation of different
            genes encoding rat prostatic 22-kilodalton glycoproteins homologous
            to human and rat cystatin
  JOURNAL   Mol Endocrinol 4 (4), 657-667 (1990)
   PUBMED   2280780
REFERENCE   10 (bases 1 to 824)
  AUTHORS   Ho,K.C., Snoek,R., Quarmby,V., Viskochil,D.H., Rennie,P.S.,
            Wilson,E.M., French,F.S. and Bruchovsky,N.
  TITLE     Primary structure and androgen regulation of a 20-kilodalton
            protein specific to rat ventral prostate
  JOURNAL   Biochemistry 28 (15), 6367-6373 (1989)
   PUBMED   2477055
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from M58167.1.
            
            On Aug 31, 2012 this sequence version replaced NM_012718.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M58167.1, M27901.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-824               M58167.1           2-825
FEATURES             Location/Qualifiers
     source          1..824
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..824
                     /gene="Andpro"
                     /gene_synonym="Crp1; RATANDPRO"
                     /note="androgen regulated protein"
                     /db_xref="GeneID:25030"
                     /db_xref="RGD:2115"
     exon            1..289
                     /gene="Andpro"
                     /gene_synonym="Crp1; RATANDPRO"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..583
                     /gene="Andpro"
                     /gene_synonym="Crp1; RATANDPRO"
                     /note="androgen regulated 20 kDa protein; cystatin-related
                     protein 1; CRP-1; prostatic 22 kDa glycoprotein
                     P22K16/P22K20"
                     /codon_start=1
                     /product="cystatin-related protein 1 precursor"
                     /protein_id="NP_036850.1"
                     /db_xref="GeneID:25030"
                     /db_xref="RGD:2115"
                     /translation="MCKTLHGTLLLLAIFVLFLNFSHATAKRTRRGMEIFEKNFIDKN
                     KLKDVYDVFKYLYNTHSADTYLSNIKNESFTMNIWGFGEIEMVKTKCRKIDSDFYKCS
                     FQREFYNLKRTPGETMYYISLPGSVRCRKLLSKLDNCPFEEQTEQLKREICYFVVYPD
                     YIEQNIHAVRFDCYTK"
     exon            290..385
                     /gene="Andpro"
                     /gene_synonym="Crp1; RATANDPRO"
                     /inference="alignment:Splign:2.1.0"
     exon            386..499
                     /gene="Andpro"
                     /gene_synonym="Crp1; RATANDPRO"
                     /inference="alignment:Splign:2.1.0"
     exon            500..824
                     /gene="Andpro"
                     /gene_synonym="Crp1; RATANDPRO"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      824
                     /gene="Andpro"
                     /gene_synonym="Crp1; RATANDPRO"
ORIGIN      
        1 atcttgaaac ctcttctcct ctgaagctcc cctttcatat ctgagaagaa aaatgtgcaa
       61 aaccctacat ggcacactgc tcctactggc catctttgtc ctgtttctga atttcagcca
      121 tgcaactgca aaacgtacca ggagaggtat ggaaattttt gagaaaaact tcatagacaa
      181 aaacaaactg aaggatgtat atgatgtctt caaatatctt tacaacacgc acagtgctga
      241 cacatatctc agcaacataa aaaatgagtc attcaccatg aacatatggg gatttggtga
      301 aattgaaatg gttaaaacca aatgtagaaa gattgattct gacttctaca aatgttcttt
      361 ccagagggaa ttctataacc taaagcggac tcctggcgaa acaatgtact atatatcatt
      421 gcctggaagc gtcagatgca ggaagctcct atctaaactg gacaactgtc ccttcgaaga
      481 acaaacagaa cagctgaaga gagaaatatg ttactttgta gtgtatcctg actatattga
      541 gcaaaatata catgctgtaa gattcgattg ttataccaaa tgagactctg agactgactg
      601 gcctgttacc caacacttgc agacattgat tctacttctg gaactctaat atggaatcac
      661 ccttcagtat ggatgccagg agtcacagag acatgcagtc cagttatgta cacctgaaca
      721 attgtcttcc ttttacattt cacatacttc ttttaaatga accattgtaa gcctgccata
      781 actaacctat gctttgctca ataaaagtac tgccattcat cttg
//
