LOCUS       NM_001007012            1831 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ALX homeobox 3 (Alx3), mRNA.
ACCESSION   NM_001007012 XM_345270
VERSION     NM_001007012.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1831)
  AUTHORS   Kuijper,S., Beverdam,A., Kroon,C., Brouwer,A., Candille,S.,
            Barsh,G. and Meijlink,F.
  TITLE     Genetics of shoulder girdle formation: roles of Tbx15 and
            aristaless-like genes
  JOURNAL   Development 132 (7), 1601-1610 (2005)
   PUBMED   15728667
REFERENCE   2  (bases 1 to 1831)
  AUTHORS   Perez-Villamil,B., Mirasierra,M. and Vallejo,M.
  TITLE     The homeoprotein Alx3 contains discrete functional domains and
            exhibits cell-specific and selective monomeric binding and
            transactivation
  JOURNAL   J Biol Chem 279 (36), 38062-38071 (2004)
   PUBMED   15226305
  REMARK    GeneRIF: Alx3 undergoes restrictive or permissive interactions with
            nuclear proteins that determine its binding to and transactivation
            from TAAT target sites selected in a cell-specific manner
REFERENCE   3  (bases 1 to 1831)
  AUTHORS   Beverdam,A., Brouwer,A., Reijnen,M., Korving,J. and Meijlink,F.
  TITLE     Severe nasal clefting and abnormal embryonic apoptosis in Alx3/Alx4
            double mutant mice
  JOURNAL   Development 128 (20), 3975-3986 (2001)
   PUBMED   11641221
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001007012.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY488087.1, SRR26643289.7408.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMN11044071
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-293               JAXUCZ010000002.1  197919381-197919673
            294-610             JAXUCZ010000002.1  197924706-197925022
            611-739             JAXUCZ010000002.1  197928305-197928433
            740-1831            JAXUCZ010000002.1  197928704-197929795
FEATURES             Location/Qualifiers
     source          1..1831
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1831
                     /gene="Alx3"
                     /note="ALX homeobox 3"
                     /db_xref="GeneID:365900"
                     /db_xref="RGD:1359270"
     exon            1..293
                     /gene="Alx3"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..1048
                     /gene="Alx3"
                     /note="aristaless 3; aristaless-like homeobox 3"
                     /codon_start=1
                     /product="homeobox protein aristaless-like 3"
                     /protein_id="NP_001007013.2"
                     /db_xref="GeneID:365900"
                     /db_xref="RGD:1359270"
                     /translation="MDPERCAPFAVGPAAGPYAAARDEAPGPQGTPDAAPHLRPAPPR
                     GPRLSRFPACGPLEPYLPEPAKPPAKYLQDLGPGPVLNGGHFYKGSSEAEEKASKAAS
                     FPQLPVDCRGGPRDGPSNVQGSPGPCLASLSVPLSPGLPDSMELAKSKSKKRRNRTTF
                     STFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQ
                     EGRNPFTTAYDISVLPRTDSHPQLQNSLWSSPGSGSPGGPCLMPPEGIPSPCMSPYSH
                     SHGNVAGFMGVPASPAAHPGIYSIHGFPPALGGHSFEPSPDGDYKSPSLVSLRMKPKE
                     PPSLLNWTT"
     exon            294..610
                     /gene="Alx3"
                     /inference="alignment:Splign:2.1.0"
     exon            611..739
                     /gene="Alx3"
                     /inference="alignment:Splign:2.1.0"
     exon            740..1831
                     /gene="Alx3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgagccgga gccggcatgg accccgagcg ctgcgcgccc ttcgcggtgg ggccggcagc
       61 gggtccttac gcggcagcaa gggacgaggc tccgggcccc caggggactc ccgatgctgc
      121 tcctcacctg cgccccgcgc caccccgcgg tccgcgcctg agccgcttcc cggcctgcgg
      181 gcccctggaa ccctacctcc cagagcccgc caagccgccc gctaagtacc tgcaggacct
      241 cgggcccggc ccggtgctca acggcggcca cttctacaag ggctcctcgg aagctgagga
      301 gaaggcctcc aaagctgcta gcttccccca gctgccagtg gattgccgag ggggtcctag
      361 agacggaccc tccaatgtgc aaggttcccc gggcccttgc ctggccagcc tgagtgtccc
      421 tctttccccg ggactccctg actccatgga gttggccaag agcaagagca agaagcgccg
      481 gaaccggaca accttcagca cattccagct ggaagaactg gagaaagtct ttcagaaaac
      541 ccactaccct gatgtgtacg ctcgggagca gctggcctta cgaacggacc tgactgaggc
      601 cagggtacag gtctggttcc agaaccgaag agccaagtgg cggaagcgtg agcgttatgg
      661 gaagatacag gaggggcgga acccctttac tactgcctat gacatctctg tgctgcccag
      721 aactgacagc catcctcagc tgcagaactc cctgtggtcc agtccaggat ctgggagccc
      781 aggagggccc tgtctcatgc ctccagaggg catcccctct ccatgtatgt ccccatactc
      841 ccactcccac ggaaatgtgg ctggcttcat gggagtacca gcctcccctg cagcccaccc
      901 tggcatctac tccatccatg gctttcctcc tgccctggga gggcacagct ttgagccttc
      961 tccagatggc gactacaagt ccccaagcct cgtctcactc aggatgaagc ccaaagagcc
     1021 ccccagcctg ctgaactgga ccacgtgatg ggttacatgg acacagactg agctgcccac
     1081 ttctcttcct gcgctggcct gctcctaatc catctctacc tggacaccaa acagcaaacc
     1141 cttttacctc ctaacctggg tggtttcaga agcttgggag agaagctggg accctcagcc
     1201 tcctgcaggg aacaggctac agggtcttat ctcttaaaat aggtagggct gcctatgaga
     1261 aagggacttc aaagcatgca ggactcttct ttaaaaaatg agtcccctca tttaaattgg
     1321 actggagaaa aggtgacaga tacccccgtt ttccaaagac tgtttctaag tccagggagt
     1381 ccaggaaaat gggtggagga tgtagagact gaacagggag gagctctctg tggttcttag
     1441 gtctggcctc acttttgcct tcttaccacc agagggcggt acgcccagat gctgggactg
     1501 acaggagccc cagaaggtga aggtcagttt aataataggt gggggtctcc tctgttccaa
     1561 acatctctca cctccaatct acagagatag tataaagtca ttttctccaa gcagggggaa
     1621 gaattccacc caacattaaa tatttgcttt catggaatca gggatatgtc atgacaacca
     1681 tattggacat caatcaaaat taaaaatctg tgattactct cacccagtct ctgagccctt
     1741 gagagccaga caccaatttt tgtaaagata ctttagcttt gttgtagtgt gctgctcagc
     1801 atggtaataa acacagtggt gtttttcact c
//
