LOCUS       XM_039097413            7306 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus alpha-kinase 2 (Alpk2), mRNA.
ACCESSION   XM_039097413
VERSION     XM_039097413.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq; corrected model.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051353.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039097413.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            frameshifts          :: corrected 17 indels
            internal stop codons :: corrected 2 genomic stop codons
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-364               JACYVU010000301.1  21317199-21317562   c
            365-491             JACYVU010000301.1  21302977-21303103   c
            492-609             JACYVU010000301.1  21298876-21298993   c
            610-2305            JACYVU010000301.1  21274334-21276029   c
            2306-3013           JACYVU010000301.1  21232748-21233455   c
            3014-3166           JACYVU010000301.1  21232593-21232745   c
            3167-3472           JACYVU010000301.1  21232285-21232590   c
            3473-3473           "N"                1-1
            3474-3568           JACYVU010000301.1  21232190-21232284   c
            3569-3697           JACYVU010000301.1  21232060-21232188   c
            3698-4117           JACYVU010000301.1  21231639-21232058   c
            4118-4228           JACYVU010000301.1  21231527-21231637   c
            4229-4261           JACYVU010000301.1  21231493-21231525   c
            4262-4366           JACYVU010000301.1  21231387-21231491   c
            4367-4367           "N"                1-1
            4368-4498           JACYVU010000301.1  21231256-21231386   c
            4499-4762           JACYVU010000301.1  21230991-21231254   c
            4763-4764           "NN"               1-2
            4765-4987           JACYVU010000301.1  21230768-21230990   c
            4988-5086           JACYVU010000301.1  21230667-21230765   c
            5087-5209           JACYVU010000301.1  21230543-21230665   c
            5210-5299           JACYVU010000301.1  21230451-21230540   c
            5300-5300           "N"                1-1
            5301-5413           JACYVU010000301.1  21230338-21230450   c
            5414-5414           "N"                1-1
            5415-5503           JACYVU010000301.1  21230249-21230337   c
            5504-5505           "NN"               1-2
            5506-5606           JACYVU010000301.1  21230148-21230248   c
            5607-5754           JACYVU010000301.1  21224882-21225029   c
            5755-5882           JACYVU010000301.1  21218397-21218524   c
            5883-5918           JACYVU010000301.1  21218266-21218301   c
            5919-6193           JACYVU010000301.1  21214265-21214539   c
            6194-6282           JACYVU010000301.1  21212691-21212779   c
            6283-6500           JACYVU010000301.1  21207186-21207403   c
            6501-6549           JACYVU010000301.1  21202779-21202827   c
            6550-7306           JACYVU010000301.1  21187015-21187771   c
FEATURES             Location/Qualifiers
     source          1..7306
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..7306
                     /gene="Alpk2"
                     /note="alpha-kinase 2; The sequence of the model RefSeq
                     transcript was modified relative to its source genomic
                     sequence to represent the inferred CDS: inserted 8 bases
                     in 6 codons; deleted 15 bases in 11 codons; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 15 ESTs, 1 Protein, and 83% coverage of the annotated
                     genomic feature by RNAseq alignments, including 6 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:498875"
                     /db_xref="RGD:1564431"
     CDS             383..6763
                     /gene="Alpk2"
                     /note="The sequence of the model RefSeq protein was
                     modified relative to its source genomic sequence to
                     represent the inferred CDS: inserted 8 bases in 6 codons;
                     deleted 15 bases in 11 codons; substituted 2 bases at 2
                     genomic stop codons"
                     /codon_start=1
                     /transl_except=(pos:4814..4816,aa:OTHER)
                     /transl_except=(pos:5186..5188,aa:OTHER)
                     /product="LOW QUALITY PROTEIN: alpha-protein kinase 2"
                     /protein_id="XP_038953341.1"
                     /db_xref="GeneID:498875"
                     /db_xref="RGD:1564431"
                     /translation="MADPGCPQRHTLRFLSTLLSQKVPEKSDVVLRCMIAGQPKPEVT
                     WYKNGQAIDSGNTVSSYEFFENQYIHLLHLPGCAQSDAAVYQVSARSCVGMICCSASL
                     EVQCLQDPQVSPDPGGGGDVAGERETEIREEDSTRRTDEKWNPCKTEESMAAGAYMPT
                     HSSPDKFDPSCSPQMVVSHDSAVSDSENPQYVKEARQRTEPFNSDNMQASSFNSNIEK
                     QDVSQLRTAHATVSGLTGDGLGHEEPNESVTPSHQTPKAQKYISFSLPLPEATLYPYP
                     SDSNSINMQPGPQVPSEDSDSDYELCPEITLTYTEEFSDDDLEYLECSDVMTDYSNAV
                     WQRNLQGTDRVFLLESDDEEMEFNECGPGGCEHFFSEMGCGPQVSGGMWSMNVATGFC
                     SYRSQPQEVGDRSSGTSRHSPLPLHSEMTLTLGPHQDGIATMTEPGRAPLPTASEAVE
                     NDCSGIRGETRDKPEAGEEFSSDNLQTMDKAETEASAKPLSGGSDKSEAKQGLKSLAG
                     ERTEEKYPGSRKTALRPTRARWPGMKANVKKQLLKDGPPKGTLDPLPKEPTKQPLTRS
                     YGQEPAHTETGAPGWNSHFREVCIPLPAEQDSKTPRPPADPLSKEGDSSFEGGGALLS
                     TLSEASQIPDQTAGRLQETIGENSYLDQMPAFSVPAEEESTFTGVQTHFVSNLTEIDR
                     GNSSLAQYLGLESCPQSPQQESRQNREGDRPGALWAESAQELRPLEDNDEEVSQAPAS
                     VALPQGDGTHFRESEALSDAFSQPTAPSLPLENVDSGSRGREAACVMGCFEAGDQETC
                     YATMDLPVGAPVDKYLPEEICPMDLELTEGQREVCDLCSPDKILAVLQAQGSESPQAT
                     YKHSEDGKSAEGALFIVTVAWTTSPEAREDATGGTAADTGNSPSIFSSTLLYNVGGFG
                     EIQAPCSENYLLCKSNEGGYGSSNLSVPIAIDTLASYGSIRECSEEQSTEPAANVDCH
                     QVTRETEGILTDATEVHKNKCRTVSVPHINDFVVGADQVSCEAQDEENSPSLPDDPLS
                     XASQVKATRETLVPAPSDAGTHGHFLLPEGQGLYLRPLQIDTQPGYESQTVEGAHSGG
                     LEEDFQEKGNGTKQCIRPQSTSHQGSLSANDFQESLPSIPAMQQEVNVEPFEHSPADS
                     GEETECSSDQRTSVSVLAEKTMGEGSPLVSSVPALPDILLGEKDGIGLGSWSVGSKVK
                     IITLEAPVFEIWPPELVTHSGYKEAEVGLTAPGRSWALSDILRAGTRPEPGALGVTTW
                     VPSPKADAIMALGNNRDNLRDAAPDRQAYCNVRTSQCLGQPRLLESSVDPVEEKELNV
                     TDSPSETSXTGEVVEMAETTDEEQGGRQHKLPHPTVANQSVNFPRILESSVDPIDDRG
                     GKPEPSDSNIEASESTTGNMCQRVDIQTAHLRVPHPQDNGEIIPNENTTNQTHVDRER
                     ADAKASQHNAAKDAIWQGQCPGEEXQGIPSVCTVSPTQDGWXQKPREAGQRGKDETEV
                     TSPMSPLSNCPAGMTYTSVTAETSNSTGHIYGGSEPRTPSTVIPVKREKGTIENKCGK
                     HVPSSNDLMDTLCTSSPKGNVTRSPTSPRAEELKSEELQIAETKPLNSSXPPNNDLGF
                     ISGEHESEKDPESLLLKDLCQKGSTLESGXKSREEQQRPVVANISKAPGAQSAIAGSE
                     EGKKQEASGXGHLAAGIKKKILSRVAALRLRLEEKERVRXNSTLRKAPKFERSLSRTD
                     EKRDPRRAPCKAEGKAPVLLKKIQAEPAPEHSGNIMLTCQFSEIHEDSTVCWTKDSKS
                     IAQLKKSAGDSSSVSLAIAQAGQKDQGLYYCCVKNSYGKVTAEFNLTAEVLKQLSSHT
                     EYRGCEEIEFSQLIFKEDVFNDSYFGDHLRGQIFTEELHFGEGVHRKAFRSTVMQGLM
                     PVFQPGHACVLKVHNAVAHGTRNNDELVQRNYKLAAQECYVQNTARYYAKIYAAEAQP
                     LEGFGEVPEIIPIFLIRRPENNIPYATVEEELIGEFVKYSIRDGKEINFLRRDSEAGQ
                     KCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGYKGFKGNCSMTFIDQFRA
                     LHQCNKYCKMLGLKSLQNNSQKPKKILGKGRAPSNSSPVKAPESGTPTEKKT"
ORIGIN      
        1 ggcctctccg gcaggcagtg tcaacaagtg tcgctcctac tgcagaaaac ggccctcaag
       61 tttcatcaca gtgatgctaa aaaatattct ccagcttcag cagtgaccta gttcgttcaa
      121 gggcaggcaa aacatgctct tcttccagag cttgggcacg ggacctttcc ctcttaggaa
      181 gacatgagtt tttctgaaac agacccaact gtgctttgat ctgtttgtgg acaagacctt
      241 gaatttgagt ccctgtcagg ggacaaggac ataaggacat ccaatcaatg cttccataca
      301 gccgggggac cccaacaacg agccagccct ccaataacat ctctcggata aacagtattg
      361 aaaaatcacg tggcatgaga ggatggcaga tccaggctgc ccccagaggc acacactacg
      421 ttttttatca acgttacttt cccagaaggt tccggagaag tctgacgtcg tgcttcgatg
      481 catgatagcc ggtcagccca agccagaggt gacttggtat aagaatggtc aagccataga
      541 ttcgggaaac accgtttcca gttacgagtt ctttgagaac cagtatattc atttgctaca
      601 tctcccaggc tgtgcccaga gcgacgctgc ggtttatcag gtctcagcga gaagctgcgt
      661 ggggatgatc tgctgttcag cctccctgga ggtccagtgt ctgcaggacc cacaggtctc
      721 tcctgatcca ggaggtggcg gggacgtggc tggggagcgt gaaacagaga tacgtgaaga
      781 agacagcaca cgccgcacag acgagaagtg gaacccttgt aaaacagaag aaagtatggc
      841 cgcaggggct tacatgccaa ctcattcctc cccagacaaa ttcgacccct cgtgctcacc
      901 ccagatggtg gtcagtcatg actctgctgt ttccgattct gagaatcccc aatacgttaa
      961 agaggcaaga caaaggacag agcctttcaa ttcagataac atgcaagcaa gttcctttaa
     1021 ttcaaatatt gagaagcaag atgtatccca gctcaggacg gcccatgcca ctgtgtcagg
     1081 gttaactggt gatggcctag gacatgaaga acctaatgag agtgtcaccc ctagtcacca
     1141 aacccccaaa gcacagaaat atatcagctt cagtcttcca ctgcccgagg caaccctgta
     1201 tccttacccc agcgacagca actccatcaa catgcagccg ggaccccagg ttcccagcga
     1261 agactctgac agtgactacg aactttgccc agagataacc ctaacgtaca cggaagagtt
     1321 ttcggatgat gacctggagt atctggaatg ttccgatgtt atgacggatt actctaatgc
     1381 ggtttggcaa aggaacctgc aggggactga ccgagttttt ttattagaaa gcgatgacga
     1441 agagatggaa ttcaatgagt gtggtcccgg tgggtgtgag catttcttca gtgaaatggg
     1501 ttgtgggcct caggtgtcgg gtggcatgtg gtctatgaat gtcgccactg gcttctgtag
     1561 ctatcgctca caaccccagg aagtggggga caggagcagc ggaacctcca ggcatagccc
     1621 attacccctg cattcagaaa tgactcttac cctgggacct caccaggacg gaatagctac
     1681 gatgacagaa ccggggaggg ctccactccc cactgcttcc gaggctgttg aaaatgattg
     1741 ttcaggaatt cggggagaaa ccagagacaa gcctgaagca ggagaggaat tctccagtga
     1801 caatctacag accatggata aggcagagac agaggcatcg gcgaagccct tgtctggggg
     1861 ctcagataag tcagaggcga agcagggttt gaaaagcctg gctggggaac gcacggaaga
     1921 aaaataccca ggcagcagga agacagccct gagacccacc agggcgaggt ggcccggaat
     1981 gaaggcaaat gtcaagaagc agctgctgaa agacggtccc ccaaaaggca ctcttgatcc
     2041 ccttcccaag gaaccaacaa agcagccctt aaccaggagc tatggacaag aacctgcaca
     2101 cacagagacg ggagctcctg gctggaattc ccacttccga gaagtgtgta ttcctcttcc
     2161 tgcagagcaa gactccaaaa cccctcgacc accagcagac ccactttcaa aggaagggga
     2221 tagcagcttc gagggaggag gagcactgct tagtacgtta tctgaagcaa gccagattcc
     2281 agaccagacc gccggccgtc ttcaggaaac cattggggag aacagttatc tcgaccagat
     2341 gccggccttt tccgtgcccg ctgaggagga gtctacgttc accggggtcc aaacacattt
     2401 cgtctccaac ttgactgaga tcgacagggg aaactcatca ttggcccagt acctggggct
     2461 ggagagctgt ccccaaagcc cccagcagga aagcagacaa aacagagaag gtgacaggcc
     2521 tggcgctctc tgggcagaat cagcacaaga actgagaccc ctagaagaca atgatgaaga
     2581 agtgtcccag gctccagcct cagtggctct ccctcagggt gatggtaccc acttcaggga
     2641 gtcagaggct ctctctgatg ctttctccca gcctactgct ccctccctcc ccttggaaaa
     2701 tgtggacagt gggtcaaggg gcagagaagc tgcgtgtgtg atggggtgtt ttgaagctgg
     2761 tgatcaagaa acatgttatg ctaccatgga tctccctgtt ggagcaccag ttgataaata
     2821 tttgcctgaa gaaatttgcc ccatggactt ggagctgaca gaaggtcaaa gagaagtatg
     2881 tgatttatgt tctcctgaca agatattggc tgttctacaa gcacaaggtt ctgagtctcc
     2941 acaggccacg tacaagcaca gcgaggatgg gaagtcagcc gagggcgctc ttttcatagt
     3001 aaccgtagcc tggaccacat caccggaggc cagagaagat gctacgggag ggacagcagc
     3061 tgatacgggg aattctccct ccatcttctc ttctacacta ctctacaatg taggagggtt
     3121 tggggagata caggcccctt gttctgaaaa ttatctcctt tgtaaaagta acgaaggagg
     3181 ctatggaagc tccaatctca gcgttccgat tgccatagac acgcttgcca gctacggttc
     3241 catcagggag tgctcagaag agcagtcaac agaaccagct gctaatgttg actgtcatca
     3301 ggtgaccaga gagacagagg gcatactaac tgatgccacc gaagtccaca aaaacaaatg
     3361 ccgcaccgtt tctgttcccc acatcaacga ctttgttgtt ggtgctgacc aggtctcgtg
     3421 tgaggcacaa gatgaagaga attccccatc gctccccgat gacccgttaa gtnaagcttc
     3481 acaggtgaag gcaaccaggg agactcttgt cccagcgccc agtgatgcag gaactcatgg
     3541 ccacttctta ctgcccgagg gacagggttt gtacctcagg cctcttcaga ttgataccca
     3601 gcctgggtat gagagccaga ctgtggaggg agcccacagc ggaggccttg aagaggactt
     3661 ccaagaaaag ggaaatggga caaagcaatg catccggcca cagagcacat cccatcaggg
     3721 ttctctttct gcaaatgatt tccaagaaag tttgccctcc atacctgcca tgcaacagga
     3781 ggtcaacgtg gaacccttcg agcactcccc agcagattcc ggggaagaaa ctgagtgtag
     3841 ctcagaccag aggaccagtg tttctgtgtt ggctgagaag accatgggag aaggcagtcc
     3901 tttggtaagc agtgtcccag ctctccctga catcctcctt ggagagaaag atggcattgg
     3961 actaggaagt tggtctgtgg gcagcaaagt gaagatcata actctagaag ctcctgtttt
     4021 tgaaatctgg cccccagaac tagtgacgca ttctgggtac aaggaggcag aagttggtct
     4081 cacggcacct ggaaggagct gggctctgtc tgacatcctc agagcaggca ccaggcccga
     4141 gccaggagcc ttgggagtaa caacatgggt tcccagcccc aaagccgatg ccattatggc
     4201 ccttggaaat aacagggaca atctgcgaga tgcagcacca gacagacaag cgtactgcaa
     4261 cgtcaggact tcccagtgtc tgggccaacc ccgactcctg gagtcatctg ttgaccctgt
     4321 tgaggagaag gagttaaatg tcacggactc tccatcagag acttcangaa ctggagaggt
     4381 ggtggaaatg gctgagacaa cggatgagga acagggggga aggcagcaca agctgccgca
     4441 ccccaccgtt gctaaccagt ctgtgaactt ccctaggatc ctggaatcct ctgtggaccc
     4501 cattgatgac aggggtggga agccagagcc ctctgactcc aacatagaag caagtgaatc
     4561 caccactgga aacatgtgtc agagggtaga catccaaact gctcacctac gggtcccaca
     4621 tccccaggac aatggggaaa tcattccaaa cgaaaacaca accaaccaaa ctcatgtaga
     4681 cagagagcga gcagatgcca aagccagtca gcataatgca gcaaaagacg ctatttggca
     4741 aggccagtgc cccggtgaag agnnacaagg gattccaagt gtgtgcaccg tgagcccaac
     4801 acaagatggt tggtgacaga agcctagaga agctgggcaa aggggaaagg acgagactga
     4861 ggtcacttcc cccatgtctc ccctttctaa ctgtcctgca ggaatgacgt acacatctgt
     4921 cacggctgag accagtaact ccacaggcca catttatggc ggatctgagc ccagaacccc
     4981 atcaacggta attcctgtga agagggaaaa aggaaccatc gagaacaagt gtgggaaaca
     5041 tgtgccctct tcaaatgatc tcatggacac actctgcact tcatctccaa agggaaatgt
     5101 cacacgctcg ccaacgagcc ctcgcgcaga ggaactgaaa tcagaggagc ttcaaattgc
     5161 ggaaaccaaa cccctaaact catcttgacc cccgaacaat gaccttggct tcatttcagg
     5221 agaacatgag tcagagaaag accctgaaag cttgttactt aaggacctgt gtcaaaaggg
     5281 ctctaccctg gagagcggan aaaagtccag agaggaacag cagaggcctg tggtggccaa
     5341 catcagcaag gcacccgggg cccaatcagc aatagctggg tcagaggagg gcaaaaaaca
     5401 agaggcttca ggangtggac acttggctgc agggataaag aagaaaattc tatccagggt
     5461 ggcagccctg aggctgaggc tagaggaaaa ggaacgtgtg aganngaact ccactctgag
     5521 gaaggcacct aagtttgaac ggtccttgtc ccgcactgat gagaaaagag accccagaag
     5581 ggccccttgc aaagctgaag ggaaagctcc agtattgctg aagaagatcc aggctgagcc
     5641 ggctcccgag cactctggaa atataatgct gacctgtcag ttttcagaaa tccatgaaga
     5701 ctctaccgtt tgctggacaa aagattcgaa gtcgatagcc cagctcaaga aaagcgcagg
     5761 ggacagctcc agtgtttcct tggccatcgc ccaagctggt cagaaggacc agggcctcta
     5821 ttactgctgc gtcaagaaca gctacggaaa agtcactgct gagtttaacc tcacagccga
     5881 agttctcaaa cagctctcca gtcacacgga atacagagga tgtgaagaga ttgaattcag
     5941 ccagctcatc ttcaaagaag atgttttcaa tgacagctac ttcggggacc acctacgcgg
     6001 ccagatcttc acggaggagc ttcacttcgg cgaaggggtg caccgcaaag ctttccgcag
     6061 cacagtgatg cagggcctca tgcccgtctt ccagcccggc cacgcatgcg tactcaaggt
     6121 gcacaacgct gtcgcccatg ggaccagaaa caatgatgaa cttgtgcaga ggaactacaa
     6181 gctcgctgcc caggaatgct acgttcagaa tactgccaga tactatgcca agatctatgc
     6241 cgctgaagca cagcctctgg aaggcttcgg agaggtgccg gagatcattc ctattttcct
     6301 tatccgtcgg cccgagaaca acatccctta cgccacagtg gaagaggagc tgattggaga
     6361 attcgtgaaa tattccatcc gagacgggaa ggaaatcaac ttcctcagac gagattcgga
     6421 ggctggtcag aagtgttgca ccttccagca ctgggtatac cagaaaacaa gtggctgtct
     6481 cctggtcacg gacatgcagg gtgtgggaat gaagttaact gacgttggca tagcaacact
     6541 ggctaaaggg tacaaaggat ttaagggcaa ctgttccatg accttcattg atcagtttag
     6601 agcgctgcac cagtgtaaca agtactgtaa aatgctgggg ctgaaatccc ttcaaaacaa
     6661 cagccagaag cccaagaaaa tcctcgggaa aggcagagct ccttcaaact cctcgccagt
     6721 gaaggcgcct gagtccggga cgcccacaga aaagaaaacc tagcatccct catcccttgg
     6781 ccaccagtga ccaccagcca gcaacgcaca ggcttgcaag tggacattgg ccaacacgcg
     6841 gggtcgcgag cctgcagcct gcagagcctc actcctcttc cgctcactat cacttgctgt
     6901 ctgctgaaac gaggatggcg aggatggcgt gggtctttct gactagccct gtggggagtc
     6961 tcagcagttc cgttgatggt ctcaaagaca gcccactgtt tgtgtacaca actagcgagt
     7021 ctaccccacc ccctctcacc gtgtgtctat ttgtgtgttg cacgtggttt gttgacaaga
     7081 gttccacact gccttgcgac tggccaccgt caaaatcctt cccaccacga ctcctcacct
     7141 cgggaatgtc tggatgtttc tgcaattaca aatgtcaagt tgtcgtatca gtgtcaccta
     7201 tgctactgtt gctgaaggtg gctttccaga tgtgaggcca tttcccggca ctacccacac
     7261 agcctggcac ctgctctgtt tcattaaatt catatttaag caaaaa
//
