LOCUS       XM_039104061            8796 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus alpha-kinase 1 (Alpk1), transcript
            variant X2, mRNA.
ACCESSION   XM_039104061
VERSION     XM_039104061.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051337.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039104061.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8796
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..8796
                     /gene="Alpk1"
                     /note="alpha-kinase 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 8 ESTs, 1 Protein, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 1 sample with support for all
                     annotated introns"
                     /db_xref="GeneID:310879"
                     /db_xref="RGD:1304613"
     CDS             652..4539
                     /gene="Alpk1"
                     /codon_start=1
                     /product="alpha-protein kinase 1 isoform X1"
                     /protein_id="XP_038959989.1"
                     /db_xref="GeneID:310879"
                     /db_xref="RGD:1304613"
                     /translation="MNNQDAVASILHECKQVLDRLLLETPDVSTEDKGEDQRCRASLS
                     GELRTLIQEAKEMKWPFVPEKWQYKQAMSPEDKTNLQDVIGAGLQQLLKINVATKMRP
                     TMTGEERAGTTSGKWPAPKTWVLGDYFNCLKQMDFKEKGQNMCWSAMSENIISKAALR
                     ASILVQDCAAAAAIVFLMDRFLYGLDVSGKLLQVAKGLHKLQPATPIAPQVVIRQARV
                     SVNSGKLLKAEYILSSLICNSGATGTWLYRNESDKVLVQSVCIQIRGQILQKLGMWYE
                     AAELIWASVIGYLSLPQPDKKGISTSLGILADIFVSMSKTDYEKFKKSPKVNLALLKE
                     FDHRLLSAAEACKLAAAFSAYTPLFVLTAVNIRGTCLLSYSCSADCPPGMKSAYLREA
                     KEAFEIGLLTKKDGELVSGKQELHSFIKAAFGLATVHCRLHGETDAVRAAKQQCSAAM
                     GKLYTFSTSLSSQDREVLSREIMSLISQVKGHLHVQSFPNADDRSYVPESFTCGLDRP
                     ILHGHVDFQQLLETYSQHHTSVCEVFESTCRNSRGHQRDAKAEVCITTLKTETSTIDT
                     VGVTLEKVCSQDSGSTAYSKMSEKDWEKLQRVRRRNWTHSEAFRVSLDQDTGTETELP
                     NHSNGRADVSSKPLRDSSSSSSWSRLSGLSSSASWEEVNGAVQDTERKESSQEEHLVD
                     TQCSTAVSEEPEGDRRICRETYLLFSKLHGVSLQTTEDHNAESSQSQLHTPALPLNST
                     TTCLASDAGLLEPPEGSNTTSLQSSPSCGSDAWSLASLGRFTAVTTYPSVQEEETSGI
                     IGDFPESKYDFKDWSGEKNEGKLTEICTGPELTFASSSVDPEGDTAESTDDGPSHSLV
                     VPGGLQGSHSMSTHRTSFSDWSVQNADSAKIGCSVKDEAVDPDASTVDEEGQMLDSTE
                     VYSIGQDGAHRPRALRSGQSDESPKSFVNGHGPSPIFDEDFSTTEEGEELGSMLKSSQ
                     NSSSCSPWWLKSPAFSRSSSEGESSWSLLNSSRSSFGSLTGQTSQEILEARTLQPDDL
                     EKLLAGVRHDWLLQRLENTGVLKSNQLQQAHSALLLKYSKKSELWTAQETVVYLGDYL
                     KVKKKGKQRNAFWVHYLHQEETLGRYVGKEYKERKGLRYHLTDVERQMTAQHYVTEFN
                     KRLYEQKIPTQIFYIPSTILLILEGRTIKGCISVEPYILGEFVKLSNNTKVVKTEYKA
                     TEYGLAYGHFSYEFSNHRHVVVDLQGWVTGNGKGLIYLTDPQIHSVDQRDVTTNFGKR
                     GIFYFFNNQHASCNEICHRLSLTRPSLEQTSKI"
ORIGIN      
        1 tgatgttatc aaaagacaag ctctccgtgt ctcctttcgg tgctctacct cggagttaga
       61 gcgcagtggg gaacgaggtg tcgcagaggc acgtgggtca acatgtttat ttgcactgga
      121 gaccaagctg gggttttcct ggtggacggt gccagacgaa gtaacacaac tcccagaata
      181 cctttcccgc agcagtccct aacggggcgt gtctcgtggt ggcgttacac aagctcgttc
      241 tgatgaagga agggcttttc ttttcagagt cccgtttcct ggaacagaag ctgttgagga
      301 gaaacgctgt gtttccggga ggttgcaccg gaattaagga tctcccagtc aggccgctgc
      361 tctctggtgt ctctctctcc cctgctctgg cataaaaaca tgcatacatt tgggtccgag
      421 aaaacctgac tcctttcctc aatcagtcac agcctctgat gtcccaggac agtgtcacta
      481 agcaatatgc ttctggggag accatgctcg tttgcttgta tggatagctt tgaagtatat
      541 ggtacctcag ccttcaaggg ccttctctat tgagaatcaa tgcctctcct aggtaattga
      601 tcaccataga cccggggaga ctcgattcat cctggacggt ggttaatcgt catgaataat
      661 caagacgctg tggcttccat actgcacgag tgcaagcaag tgctggaccg tctcttgttg
      721 gaaacgccag atgtgtctac agaggacaag ggtgaggacc agcggtgcag agcctcactc
      781 tccggcgagt taaggaccct gatccaggag gcgaaggaaa tgaagtggcc cttcgtgcct
      841 gaaaagtggc agtacaaaca agccatgagc ccagaggaca aaacaaacct gcaggacgtg
      901 attggcgccg ggctgcagca gttactgaaa ataaatgttg ccactaagat gagacccact
      961 atgactggtg aagaaagagc agggaccaca tctggaaagt ggcctgcccc taaaacatgg
     1021 gttttggggg actacttcaa ctgcctgaag caaatggact tcaaagagaa ggggcagaac
     1081 atgtgctgga gtgctatgtc agagaacatc atctctaagg cggccttgcg agcctccatc
     1141 cttgtccagg actgcgctgc cgccgccgct attgtcttct tgatggaccg gttcctgtac
     1201 ggactcgacg tctcgggaaa actcctgcag gtcgccaaag gcttgcacaa gctgcagccc
     1261 gcgacgccca tcgccccgca ggtggtcatc cgccaagccc gggtctctgt caactcaggg
     1321 aaactgttga aggcagagta catcctgagc agcctgatat gcaacagcgg tgcaactggt
     1381 acctggctct ataggaatga gagtgacaag gtcctggtac agtcggtgtg catacagatc
     1441 agagggcaaa ttctgcagaa gctaggcatg tggtatgaag cggcagagtt gatatgggcc
     1501 tccgtcatag gatatttgtc actccctcag ccagataaga agggcatttc cacgtcattg
     1561 ggcatactgg cggacatctt tgtgtctatg agcaaaactg attatgagaa gtttaagaag
     1621 agcccaaagg ttaacttggc cttgctcaag gagttcgacc atcgtttatt gtcagctgcg
     1681 gaagcctgca aactggcagc tgccttcagt gcctacacgc ccctgttcgt gctcacagct
     1741 gtgaacatcc gtggaacatg tctattgtca tacagttgtt ctgctgactg ccctccagga
     1801 atgaaaagtg cgtatctgcg tgaagccaaa gaagcctttg agattggcct cctcaccaag
     1861 aaagacggcg agctggttag tggaaagcag gagctacaca gcttcatcaa agctgccttt
     1921 ggcctcgcca cggtgcactg caggctccat ggggagacag atgcagtccg tgcagcaaag
     1981 cagcagtgca gcgcagctat gggcaagctc tacaccttca gcacttccct ctcgagccag
     2041 gacagagaag tcctgtctcg ggaaatcatg tccctcatca gccaggtgaa gggacatcta
     2101 cacgttcaaa gcttcccaaa tgcagatgat agatcttatg tcccagagag tttcacgtgt
     2161 ggtttagata ggcccatctt gcatgggcac gtggatttcc aacagcttct cgaaacctac
     2221 tcccagcacc atacttcagt gtgcgaggta tttgaaagca cgtgtaggaa cagcagaggc
     2281 caccagagag acgcaaaggc agaggtctgt atcaccactc tgaagacgga aacaagcact
     2341 atagatactg tgggggttac tctagagaaa gtgtgctccc aagacagcgg gagtacagct
     2401 tattccaaga tgtctgagaa agattgggag aagctccaaa gagtaaggag gagaaactgg
     2461 acccattccg aggcgtttcg agtctccctg gatcaagata cggggacgga gactgagcta
     2521 ccaaaccaca gcaatggcag ggcagatgtc tccagcaagc ctctgagaga cagctctagc
     2581 tcgagttctt ggagcagact gtcagggctc agctcttccg caagctggga ggaagtgaac
     2641 ggtgctgttc aggatacaga aaggaaagag tctagccaag aggaacatct tgtggacact
     2701 caatgctcca cagcagtgtc tgaggaaccc gagggggaca gacgtatatg tagagagacg
     2761 tatttgctgt tttccaagct ccacggtgtc tctcttcaga cgaccgaaga tcacaatgca
     2821 gagtcttcac aaagtcagtt acacacaccc gcccttcctc tcaactcgac gaccacttgt
     2881 ttggcctcag atgcagggct cttagaaccc cctgaaggat ccaacactac ttctcttcag
     2941 tccagtcctt catgtggttc tgatgcctgg tccttggcta gtttgggcag gttcacagct
     3001 gtgaccacat atccttcagt tcaggaagaa gaaacttctg gaataattgg tgatttccca
     3061 gaatccaagt atgacttcaa agactggagt ggagaaaaga atgagggaaa actcactgaa
     3121 atatgcacgg ggcctgaatt aacgtttgcc tcctcctcgg tagacccaga aggagacacg
     3181 gcagaaagca cagatgatgg cccatcacac tctctggtag tcccaggagg tttacaaggc
     3241 agccattcaa tgtctacgca tcggacttcc ttttcagatt ggtctgttca aaatgctgac
     3301 tcagcaaaga ttggctgctc cgtcaaagac gaagctgtgg accctgatgc ttctacggtg
     3361 gatgaggagg gccaaatgct tgacagcaca gaggtctact ccattggcca agatggcgct
     3421 cacagaccac gtgctttaag gtccggtcag agtgatgaga gtccaaagtc ctttgtaaat
     3481 ggccacggtc cctcccctat cttcgatgag gacttcagca ccacagagga aggagaggaa
     3541 cttgggagca tgctgaagag tagccagaac tccagctcat gctcgccgtg gtggctaaaa
     3601 tcacccgcct tttcccgcag ttcgtctgag ggggaaagct cctggtctct gctgaactct
     3661 agccgaagtt cctttggctc actgacagga cagaccagcc aagagatcct tgaggctcgc
     3721 accctgcagc ctgatgacct tgaaaagctt ctagcagggg tgaggcatga ttggctgctt
     3781 cagagactgg agaatacagg agttttgaag tccaatcaac tccaacaagc acacagtgcc
     3841 ctcctgctaa aatattccaa aaagtctgag ttgtggacgg cccaggaaac ggtggtatat
     3901 ctgggagact acctgaaagt gaagaagaag ggcaagcaga gaaatgcatt ctgggtccac
     3961 tatctccatc aagaggaaac cctggggaga tacgttggga aagaatataa agagcggaag
     4021 gggctccggt accacctcac agatgtggag cggcagatga cagcgcagca ctacgtgaca
     4081 gagtttaaca agagactcta cgagcaaaag atcccaacgc agatattcta catcccgtcc
     4141 acaatattgc tgattttgga aggcaggact ataaaggggt gcatcagtgt ggagccttac
     4201 atcctgggag aattcgtcaa gttatcaaat aacaccaaag tcgtcaagac cgagtacaaa
     4261 gctacagaat acggcttggc ctacggccat ttttcttacg agttttctaa ccacagacat
     4321 gttgtggttg atttacaagg ttgggtgact ggtaatggaa aaggcctcat ctatctcaca
     4381 gatcctcaga ttcactctgt agatcagaga gacgtcacta caaactttgg aaagcggggc
     4441 atattttact tctttaataa ccaacatgca agctgtaatg aaatatgcca tcgtctttct
     4501 ctgacgagac cttcactaga gcaaacaagt aagatatagg cagtgggttg ggagcctagc
     4561 atcaaatctg cctccttcca ggaatacaaa gcgaggcaag tgttgacgta ttgatcagtt
     4621 gggccaatgg atgattccag ctattgactt atgagaggaa tacacaagtg ttgatttcag
     4681 gcctacactt gcttgccagg acaagatcct gtagacctgt tccctctgac acaggggcat
     4741 gtctggaggc tgtcctaggc ctcacagttg tatatgatgt tcagggtcct gagttgcatg
     4801 aggacaacat ggaaaaggtc tccaaccaac ccacaatgga tgcaaacttg agctggaaac
     4861 aaactgctgt cattaagcca ttgtgatttc tgtttgtttt gttgttgctt tgtgggttgg
     4921 ttctggttgg gttgggtttt tggtctgttt ggagagtttt gttttttttt tttaatctgt
     4981 taaaactgat actgttgctg ctttcttatt aaccaaagag ttctttgtaa atttaaaaca
     5041 tccaggctcc tgaaaagatt tcaattgtcg tttccctttt aatatttgcc attttgtaaa
     5101 actgttgtcc atacagactg ttcttttgac tgagatgact tcttcacctt tatttcatgc
     5161 ttgtgtgtga taccagatat ttctgtgttc tgggtttctt tctggttctc ccatgttttc
     5221 ttctagtatt tctatctatg aaaggtgcga tggaagagtg gtcacatacc acagggtcac
     5281 cacagcctat tgctttcccc atacatcttc ttcacacaag attggtaatt ccttctgctg
     5341 aaagaattgt attaatgctc agtggtacca ccacatttaa ggtgtgtcgc ctcacctggg
     5401 ttaacacaat gtaggaattc cctcatatac aggcttggag ctttgtctcc tagatatttc
     5461 tatgtcttgt caaactgact atcaataccc accatcacgt actgtgctaa ggaagtccag
     5521 gataaggggt ggtcatcaag ggttgcaatg gagtttgtgt agaaggatgg acagagaatt
     5581 gtatatccta gaatgaagac gaagcagagg aagcaagagt gacagactgg agggatgtga
     5641 cagccaaaaa tgccgaggaa gggagagtga acaagtggaa aaaggaaaat ggacagccac
     5701 taagaaaaga gaagcattgg atgacatcac agggcaggga gggtgagaag gtcgcacacc
     5761 aaaactacaa cccttattgg aacagaaaaa cagctgccag cagaatgggc agggccccag
     5821 ggctggaagt gctcccaagg gctctgagta tatcactttc taggatcccg gggccccact
     5881 ccttcctcac tgggcctggg ccaggttatc ttcccttgca tgagaagact ttgcatcagc
     5941 tgcaacgcct tgggtcctga ggggtgtaca tgtggagagc agctctggga gcaccaagca
     6001 gcccctttca atttacaatt gaattcctct aagccctttc tcaagagcaa cctcccatcc
     6061 catccatttt attgctggat aatattccaa acttctaaaa tcaatgtctt cactaaaagt
     6121 gtgactataa ctccggcctg aaatagcatt ctgaggacat ttaggacctt tgaatacaga
     6181 ctgagcttta gatgaagtca ccaagtcatg aagtccaagc caaggagagc gaaacagtga
     6241 gggagggcac agagcatcat ctttcccttg catctgcgcg gagccggatg agggcacatg
     6301 ggttagatta taacactccg tgtacttcct cacagattcc taatttccat actttttcat
     6361 aaatgtgagg taattgaaag gagtgccaaa tcaaatgaag agcgaacaga gagagatgag
     6421 ggtgatcaag atttttggca aactaatcaa aaagaagtac aagaaagagt agccaacggc
     6481 gtaaaatcct acagaaaaaa aaatcaagaa aaaatacaat atgtacttac ttaatgaggg
     6541 agtggggaca gtacgaagtg attgtgacaa caagaaaggc cattaactga cagagaggtg
     6601 ttaaatatca tagaactgag gtcagtaatc ctgagtccat gcccatgagt caaacctact
     6661 gtgaaagtca ttggtcgtta gaacagtttt tttcaatgct attctctctg aagaggtgga
     6721 gaagaactgc tgacctgtga actcagattc accctcaaac cccccaaatc aggggaaagt
     6781 gtaggccaag gaaatctact taccctgcct gtgggatctg ggcctggtta aaagtgtact
     6841 tgacttagca aacctccata tgaacagctc cttctagaat aaaatgtgct actttctcct
     6901 ctggtttcca aatcccttgt ctgtaggcca gcagagccat cagatgatgg tggtacccag
     6961 aaatccctca atcagcatcc tggggactca ttctgggaag caggtggatc ctctgttcag
     7021 ggtgcatagc cagggaccat gctgatgtgg gccagtccta tcccaatcca ctgcagctcc
     7081 acttcctgtt cccctcttgc tgggaccagc atgggtgttt gttgtactca agctatgccc
     7141 ttctctgagt cactccatat tttgtaaaac catgattttt catttttcag gcttgctcag
     7201 atagattctg tcttagaaac aacctttggc tccaggtcaa ggtaggggga tgaccacgtc
     7261 cctgggcaga taagtaaaca ccatctgtct ggcaccaccc acacagcaca ggctaataaa
     7321 tggcattcct tggagtagac agggtgaatt tactgggatg aattgaggct gtacgggcac
     7381 acaggtgtaa ttaaaatcat accaggaaaa caaaatgttc taggcacttc tctgttgctg
     7441 tgttaaaaca ccacagccga ggcaacttag agaagtttat ttgggcttat ggttgtggaa
     7501 ggataagagt ctatgatggt ggaatatgtc aaaaagcagc caagcatgaa gcagacaact
     7561 gagaactcca actgggtagt ggtggtgcaa agctttgatc cctgaactca ggaggcagag
     7621 gccagtggat ctctgtgagt ttgaggcaag cctggtccac agagcaagtt tcatgatagt
     7681 ctatacaaag aatctcttgt ctcaaaacaa caagaaagga agaaggagag agagagaggt
     7741 agagagagag agagagaaga gagaagaaag agaaggaaag taactcacat tttgaacctc
     7801 aaaactgaat caaagaaaat atactagaaa tgacatgagg aatttaatct caataccaaa
     7861 cctccagcaa tatactccct ccaaaacgtt cgcatcacct gaccacctcc acctccaccg
     7921 ccaaacagca ccattaacta caccaagtgt tcaaataccc aaactatagg aatagtccca
     7981 tttcagccac cacatcatac tcagtgtccc cgtaggctcc tggtcatata atacaaaatg
     8041 catttcacca agcctcaaag gtcctcacag tctttcacag tgtctactgt ttcaaagtcc
     8101 aaagtcgctt ctaagactca ataaaaagct aattacatac ttctaataca tgatggcaca
     8161 gaatattcat taccttctcc aaagagagga attggggtag agtaaggaaa tacctagacc
     8221 aaaacaagac agaaaccagt aggggcaagc attggattct atagttccag atctcgtgtc
     8281 tgaacattca tttcacaggg cttagatgtc tcaacccctg cagctttgct gacttcatca
     8341 ctcatctctc tcttgggctg gttccacttc cagtaagctg ccctccttgt cagatacctc
     8401 acagctctgc catcgtcaac accttgtggt cctttagtag tttgaatgag gatcgtctac
     8461 catagtcttg agcagttgta cactgggtcc cctgttggtg gtactgtttg ggaaggatta
     8521 tgaggtgtgg ctttgttggg ggaaagtgtt gttggaagtg gacattgaga gtttttaaaa
     8581 tctcatgcca tttcaagttt tctgtctctg ctttcaactt tgtgtttgaa gatgtgagtt
     8641 cccaccttct gttccaggca tcgtacctgc tgtttgctac atgtcttcct gccatggcgg
     8701 aatcatccct ctggaactat aagcccaaat aaactgtctc ttctattaat agtgttggtc
     8761 ttgatgttta tcacaataat aaaaaagtaa ccaata
//
