LOCUS       NM_001127450             972 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus alkB homolog 6 (Alkbh6), mRNA.
ACCESSION   NM_001127450 XM_001079013 XM_214896
VERSION     NM_001127450.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 972)
  AUTHORS   Lee DH, Jin SG, Cai S, Chen Y, Pfeifer GP and O'Connor TR.
  TITLE     Repair of methylation damage in DNA and RNA by mammalian AlkB
            homologues
  JOURNAL   J Biol Chem 280 (47), 39448-39459 (2005)
   PUBMED   16174769
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC082048.1 and CB581428.1.
            
            On or before May 21, 2008 this sequence version replaced
            XM_001079013.1, XM_214896.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB581428.1, SRR8487227.1712.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-422               BC082048.1         1-422
            423-581             CB581428.1         429-587
            582-972             BC082048.1         548-938
FEATURES             Location/Qualifiers
     source          1..972
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..972
                     /gene="Alkbh6"
                     /note="alkB homolog 6"
                     /db_xref="GeneID:292780"
                     /db_xref="RGD:1566318"
     exon            1..61
                     /gene="Alkbh6"
                     /inference="alignment:Splign:2.1.0"
     exon            62..140
                     /gene="Alkbh6"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..803
                     /gene="Alkbh6"
                     /EC_number="3.4.22.17"
                     /note="alkylated DNA repair protein alkB homolog 6;
                     probable alpha-ketoglutarate-dependent dioxygenase ABH6;
                     alkB, alkylation repair homolog 6"
                     /codon_start=1
                     /product="alpha-ketoglutarate-dependent dioxygenase alkB
                     homolog 6"
                     /protein_id="NP_001120922.1"
                     /db_xref="GeneID:292780"
                     /db_xref="RGD:1566318"
                     /translation="MEEQDARIPALEPFRVEQAPPLIYYVPDFISKEEEEYLLRQVFN
                     APKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLSLFGGLPANHVLV
                     NQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPRQPDDDVPPEQPRPPQQPIT
                     SLLVEPRSLLVLRGTAYTRLLHGITATRVDELDSTSLPPNAAACQSALPGARLVRGTR
                     VSLTIRRVPRVLRASLLLSK"
     exon            141..209
                     /gene="Alkbh6"
                     /inference="alignment:Splign:2.1.0"
     exon            210..270
                     /gene="Alkbh6"
                     /inference="alignment:Splign:2.1.0"
     exon            271..422
                     /gene="Alkbh6"
                     /inference="alignment:Splign:2.1.0"
     exon            423..539
                     /gene="Alkbh6"
                     /inference="alignment:Splign:2.1.0"
     exon            540..932
                     /gene="Alkbh6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgggggggc gtgcgaccat gagcatgttg agtctggaaa ttggagaaga cgttgtggac
       61 ggacggcaca caaggagttg atatccatgg aggagcagga cgccaggatc ccagcactgg
      121 aaccattcag ggtggaacag gcgccacctc taatctacta tgtccctgac ttcatctcca
      181 aggaagagga ggagtatttg cttcgacagg ttttcaatgc cccaaagcca aagtggaccc
      241 agctgtccgg gaggaagctt cagaactggg gtgggctccc ccacccccgg gggatggtcc
      301 ctgagcgact ccctccatgg cttcaacgct acgtggacaa agtgtctgac ctcagccttt
      361 ttgggggtct cccagctaac catgtccttg tgaaccagta cctgcctggg gagggcatca
      421 tgcctcatga agatggacca ttgtactacc caacagtcag caccattagc ctgggctccc
      481 atactgtcct tgacttctat gaacctcggc agccagacga tgacgtccct ccagaacagc
      541 ccaggcctcc tcagcagccc atcacctcgc tgctggtgga accacggagc ctgctggtgc
      601 tccggggcac ggcttacaca cgtctgctcc acggcatcac agccacccgc gtagatgagc
      661 tggactccac ctcgctgccg cccaatgccg ctgcctgcca gtcggcgttg cccggagccc
      721 gcctggtgcg tggcacccgt gtctcgctga ccattcgacg tgtaccccgc gtgctgcgcg
      781 ccagcctcct gctgagcaag tgaccaccag gctccaaaac tcctgacctt ggaaccttag
      841 ggcagaggta gctgcccagg gttatttatt ttcccagtaa ctgtggaaac cacggagaag
      901 tcaccattcc aaataaacag aaaatacctt taaaaaaaaa aaaaaaaaaa aaaaaaaaaa
      961 aaaaaaaaaa aa
//
