LOCUS       NM_001105920            1803 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus alkB homolog 4, lysine demethylase (Alkbh4),
            mRNA.
ACCESSION   NM_001105920 XM_001077092 XM_222071
VERSION     NM_001105920.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1803)
  AUTHORS   Kweon SM, Chen Y, Moon E, Kvederaviciute K, Klimasauskas S and
            Feldman DE.
  TITLE     An Adversarial DNA N6-Methyladenine-Sensor Network Preserves
            Polycomb Silencing
  JOURNAL   Mol Cell 74 (6), 1138-1147 (2019)
   PUBMED   30982744
REFERENCE   2  (bases 1 to 1803)
  AUTHORS   Li MM, Nilsen A, Shi Y, Fusser M, Ding YH, Fu Y, Liu B, Niu Y, Wu
            YS, Huang CM, Olofsson M, Jin KX, Lv Y, Xu XZ, He C, Dong MQ,
            Rendtlew Danielsen JM, Klungland A and Yang YG.
  TITLE     ALKBH4-dependent demethylation of actin regulates actomyosin
            dynamics
  JOURNAL   Nat Commun 4, 1832 (2013)
   PUBMED   23673617
REFERENCE   3  (bases 1 to 1803)
  AUTHORS   Bjornstad LG, Zoppellaro G, Tomter AB, Falnes PO and Andersson KK.
  TITLE     Spectroscopic and magnetic studies of wild-type and mutant forms of
            the Fe(II)- and 2-oxoglutarate-dependent decarboxylase ALKBH4
  JOURNAL   Biochem J 434 (3), 391-398 (2011)
   PUBMED   21166655
REFERENCE   4  (bases 1 to 1803)
  AUTHORS   Lee DH, Jin SG, Cai S, Chen Y, Pfeifer GP and O'Connor TR.
  TITLE     Repair of methylation damage in DNA and RNA by mammalian AlkB
            homologues
  JOURNAL   J Biol Chem 280 (47), 39448-39459 (2005)
   PUBMED   16174769
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473973.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_222071.3, XM_001077092.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166568.1, EV771101.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1803
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q12"
     gene            1..1803
                     /gene="Alkbh4"
                     /gene_synonym="RGD1308608"
                     /note="alkB homolog 4, lysine demethylase"
                     /db_xref="GeneID:288587"
                     /db_xref="RGD:1308608"
     exon            1..142
                     /gene="Alkbh4"
                     /gene_synonym="RGD1308608"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..928
                     /gene="Alkbh4"
                     /gene_synonym="RGD1308608"
                     /EC_number="1.14.11.51"
                     /note="alkylated DNA repair protein alkB homolog 4; alkB,
                     alkylation repair homolog 4; alkB homolog 4, lysine
                     demthylase"
                     /codon_start=1
                     /product="alpha-ketoglutarate-dependent dioxygenase alkB
                     homolog 4"
                     /protein_id="NP_001099390.1"
                     /db_xref="GeneID:288587"
                     /db_xref="RGD:1308608"
                     /translation="MAAVAAEVSHLQECGCKGIRTCLICERRLQRDPPWQISLQKKCC
                     FLYCPDTGWAMGAEGSDFEGWAFPFPGVTLTQDFVTPEEEAEMVRLMDCDPWKPSQSG
                     RRKQDYGPKVNFRKQKLKMAGFQGLPGFSQKVVQRMGLYPGLEDFQPVEQCNLDYSPE
                     RGSAIDPHLDDSWLWGERLVSLNLLSATVVSMSREAPGSLLLCPVPSVGPDAFEGNSV
                     APSRSVPCQEVEVAISVPRRSLLVLTGAARHQWTHAIHRRHIKARRVCATFRELASEF
                     LPGGKQQELGQELLRTALSFQGRPV"
     exon            143..340
                     /gene="Alkbh4"
                     /gene_synonym="RGD1308608"
                     /inference="alignment:Splign:2.1.0"
     exon            341..1803
                     /gene="Alkbh4"
                     /gene_synonym="RGD1308608"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccctagctgc tccgagggtg caatggcggc tgtagcggct gaagtttctc atttgcagga
       61 gtgcggctgt aaaggtatcc ggacctgtct catctgcgag agacgactcc agagggaccc
      121 gccctggcag atctcccttc agaaaaaatg ctgtttcctc tactgcccgg acacaggctg
      181 ggccatgggg gccgagggct ctgactttga gggttgggcg ttccccttcc cgggagtgac
      241 actcacacag gactttgtga ccccggagga agaagccgag atggtgcgtc tcatggactg
      301 cgacccttgg aagccttcgc agtccgggag gaggaagcag gactatggcc ccaaagtcaa
      361 ttttcggaag cagaagctga agatggcggg cttccagggt ctccctggct ttagccagaa
      421 ggtagtccag agaatgggcc tttacccggg gctggaggac ttccagcctg tggaacagtg
      481 taacctggac tacagccctg agcggggctc tgccatcgac ccccacctgg atgactcctg
      541 gctgtggggc gagcgcctgg tgagcctcaa cctcctgtcg gccacagtgg tgtctatgtc
      601 ccgagaggcc cccggcagcc tgctgctctg cccagtcccc tctgttggac cggatgcttt
      661 tgagggcaac agcgtggccc ctagcaggtc cgtcccctgc caagaggtgg aggtggccat
      721 ctcagtaccc cgccgctccc tgctggtgct tacaggggcc gcccggcacc agtggacaca
      781 cgccatccac cgcagacaca tcaaggcccg ccgtgtgtgc gccaccttca gggagctggc
      841 cagtgagttc ctgcctggag ggaagcagca agaactgggc caagaactgc tgcggactgc
      901 actgtccttc caagggagac ccgtgtgaat gccttccatg acacaagagc tgtcgctggc
      961 tgacagcttg gctccagcgt gaccgaccac tggaggggca aacactgagg tctccccaca
     1021 actcagtaaa ctcacggggt tttgagacaa gtgctcatag agcccaggct agctccaatt
     1081 ctgtagctga ggatgacctt gacttttcta cctctacttc caaaagctct ggaattacag
     1141 acgtacactg ccaggcctgg ctttattttt gttttgtttt gtttctcttt ctgagacagg
     1201 gtctctggcc tggacaggtc tcaaactctg tattcagcca aggatgactt tgaactccca
     1261 atcctcctgc ctctacctct tgaatgctgg gattgccagc acaccgtcat attcagcatt
     1321 ttcggtgctg ggatggcagc gcgtgtcctg cctactgagc tgtacccctc ctgttggggt
     1381 tttttgagta aaggtgtcag gcggactaga ctggcctggt actcattgtg tagcctggct
     1441 ttgaaccccc tgatcctcct gcctcagcct cccaattgct gagatggccg tgcactggtt
     1501 aggttttagt aggagtcatc tgacccctga cgttgcgaca gtcacacacc ctgcctggaa
     1561 ctggtctgct gggcgtggac tgtggcctct ccaggtgacg cagtatgtca cagtatggag
     1621 ggattcagtc ttttatctgg gacgagcacg atggctcagt ggctaaaggc gcttgccacc
     1681 aagcctaatg acctgagctc agtctctgga atccacatga tgaaaggtgt gtcccctgat
     1741 ctcccatgta tgttaccact ctgataaaat ccataatgaa cggaaaactc tggtctcctg
     1801 tga
//
