LOCUS       NM_001126273            1235 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus alkB homolog 2, alpha-ketoglutarate-dependent
            dioxygenase (Alkbh2), mRNA.
ACCESSION   NM_001126273 XM_001080423 XM_222273
VERSION     NM_001126273.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1235)
  AUTHORS   Yang,C.G., Yi,C., Duguid,E.M., Sullivan,C.T., Jian,X., Rice,P.A.
            and He,C.
  TITLE     Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to
            dsDNA
  JOURNAL   Nature 452 (7190), 961-965 (2008)
   PUBMED   18432238
REFERENCE   2  (bases 1 to 1235)
  AUTHORS   Lee,D.H., Jin,S.G., Cai,S., Chen,Y., Pfeifer,G.P. and O'Connor,T.R.
  TITLE     Repair of methylation damage in DNA and RNA by mammalian AlkB
            homologues
  JOURNAL   J Biol Chem 280 (47), 39448-39459 (2005)
   PUBMED   16174769
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166547.1.
            
            On or before May 7, 2008 this sequence version replaced
            XM_222273.4, XM_001080423.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166547.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1235
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..1235
                     /gene="Alkbh2"
                     /gene_synonym="RGD1306377"
                     /note="alkB homolog 2, alpha-ketoglutarate-dependent
                     dioxygenase"
                     /db_xref="GeneID:304578"
                     /db_xref="RGD:1306377"
     exon            1..684
                     /gene="Alkbh2"
                     /gene_synonym="RGD1306377"
                     /inference="alignment:Splign:2.1.0"
     CDS             471..1190
                     /gene="Alkbh2"
                     /gene_synonym="RGD1306377"
                     /EC_number="1.14.11.33"
                     /note="alpha-ketoglutarate-dependent dioxygenase alkB
                     homolog 2; alkB, alkylation repair homolog 2"
                     /codon_start=1
                     /product="DNA oxidative demethylase ALKBH2"
                     /protein_id="NP_001119745.1"
                     /db_xref="GeneID:304578"
                     /db_xref="RGD:1306377"
                     /translation="MDRFLVRPDRGDIQGAAEEPAPTGEASGDMQSPGWQHFRAEGLN
                     CDYTVLFRKAEADQIFRELEQEVEYFTGALAKVQVFGKWHSVPRKQATYGDAGLTYTF
                     SGLTLTPKPWIPVLERVRDQVCRVTGQTFNFVLVNRYKDGCDHIGEHRDDERELAPGS
                     PIASVSFGACRDILFRHKDSRGKRPRRAVEVVRLQLAHGSLLMMNHPTNTHWYHSLPI
                     RKRVLAPRINLTFRKILPTKK"
     exon            685..883
                     /gene="Alkbh2"
                     /gene_synonym="RGD1306377"
                     /inference="alignment:Splign:2.1.0"
     exon            884..1211
                     /gene="Alkbh2"
                     /gene_synonym="RGD1306377"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagggcgcct ggggctgcag tgctgccgag attcgtgcgt atgtgcagag ccctggcgcg
       61 ggtcgccgct ccggaccctc ccgtggagca cggctgcgtc cccgtgctag cctaccccgc
      121 ggggcgcaga acagaggcac cctgtttttc cgggtaactg ggcgagcccc gctcctctgc
      181 gcctgcgtcg tcccatgtgt agcctgaagg tttgggcagc cgtttgtagc ctgtgctccc
      241 attccggagc gatcctgggg atgcgcgctc tggatccctg cagttaggct cctggagcct
      301 gaggacgcgt ggttcgggtc cgcttgtgct aggacgactt gagctaaaga gcaggcctgt
      361 ggggtttgca agctccccgc ctggctgctg cccgccaggc acctcctagg agttttaatg
      421 cgctcgtttt ccttggtagg acgcgtctgt ggcttgcggg aggcggcggc atggacagat
      481 tccttgtgag accggaccga ggcgacatcc aaggggccgc ggaggagccc gcccctacgg
      541 gagaagcctc aggcgacatg cagagccccg gctggcaaca ctttcgcgcg gaaggtctga
      601 actgcgatta caccgtcctg ttccgcaagg ccgaggcaga ccagattttc cgagagttgg
      661 agcaagaagt ggagtatttt accggtgcac tggccaaggt gcaggtgttc ggaaagtggc
      721 acagtgttcc caggaagcag gcaacctatg gggacgctgg cctcacatat acgttttctg
      781 gtcttaccct gacaccaaag ccgtggattc cggttctaga gcgcgttcga gaccaagtct
      841 gcagggtgac aggacagacc ttcaactttg tgctcgtgaa caggtacaaa gacggctgtg
      901 accacattgg ggagcacaga gacgatgaac gagaactggc cccggggagc cccatcgcgt
      961 ccgtctcctt cggtgcctgc agagacatcc tcttccggca caaagactct cgggggaaga
     1021 ggccccggag ggcagtggag gtggtcaggc tgcagctggc ccatggaagc ctgctgatga
     1081 tgaaccaccc caccaacacc cactggtacc acagtctccc catccgcaag agggtcctgg
     1141 ctcctcggat caacttgact tttaggaaaa ttttacctac taagaaataa aacatgtctt
     1201 tattattttt aaaaaaaaaa aaaaaaaaaa aaaaa
//
