LOCUS       NM_001142363            1445 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ALG3, alpha-1,3- mannosyltransferase (Alg3),
            transcript variant 1, mRNA.
ACCESSION   NM_001142363
VERSION     NM_001142363.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1445)
  AUTHORS   Korner,C., Knauer,R., Stephani,U., Marquardt,T., Lehle,L. and von
            Figura,K.
  TITLE     Carbohydrate deficient glycoprotein syndrome type IV: deficiency of
            dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase
  JOURNAL   EMBO J 18 (23), 6816-6822 (1999)
   PUBMED   10581255
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM075565.1, CO401508.1 and BC088475.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                FM075565.1         1-11
            12-644              CO401508.1         1-633
            645-1445            BC088475.1         528-1328
FEATURES             Location/Qualifiers
     source          1..1445
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q23"
     gene            1..1445
                     /gene="Alg3"
                     /note="ALG3, alpha-1,3- mannosyltransferase"
                     /db_xref="GeneID:287983"
                     /db_xref="RGD:1306004"
     exon            1..214
                     /gene="Alg3"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..1335
                     /gene="Alg3"
                     /EC_number="2.4.1.130"
                     /note="asparagine-linked glycosylation 3 homolog (yeast,
                     alpha-1,3-mannosyltransferase); asparagine-linked
                     glycosylation 3 homolog (S. cerevisiae,
                     alpha-1,3-mannosyltransferase);
                     alpha-1,3-mannosyltransferase ALG3;
                     dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl
                     mannosyltransferase; asparagine-linked glycosylation 3,
                     alpha-1,3- mannosyltransferase homolog"
                     /codon_start=1
                     /product="dol-P-Man:Man(5)GlcNAc(2)-PP-Dol
                     alpha-1,3-mannosyltransferase"
                     /protein_id="NP_001135835.1"
                     /db_xref="GeneID:287983"
                     /db_xref="RGD:1306004"
                     /translation="MAAGLRKRGLPGSVVQPAGIWKQWLQRAWQERYLLLREPRYTLM
                     VASCLCLAEVGITFWVIHRVAYTEIDWKAYMAQVEGFINGTYDYTQLQGDTGPLVYPA
                     GFLYIFTGLYYATDRGTDIPTAQNIFAVLYLVTLVLVFLIYHQTSKVPPFVFFFMCCA
                     SYRVHSIFVLRLFNDPVAMALLFLSVNLFLAQRWSWGCCCFSLAVSVKMNVLLFAPGL
                     LFLLLTQFGFRGALPKLALCAALQVVLGLPFLLENPVGYLSRSFDLGRQFLYQWTVNW
                     RLLPEAIFLHRAFHLALLAAHLSFLLLFALCRWHRTGESILSLLKDPSKRKVPPQPLT
                     PNQIVSVLFTSNFIGVCFSRSLHSQFYVWYFHTLPHLLWATPARWLTHLLRLLVLGLI
                     ELSWNTYPSTPFSSAALHLCHAVTLLQLWLSPQFFPRSVQPSRKTH"
     exon            215..314
                     /gene="Alg3"
                     /inference="alignment:Splign:2.1.0"
     exon            315..462
                     /gene="Alg3"
                     /inference="alignment:Splign:2.1.0"
     exon            463..623
                     /gene="Alg3"
                     /inference="alignment:Splign:2.1.0"
     exon            624..744
                     /gene="Alg3"
                     /inference="alignment:Splign:2.1.0"
     exon            745..950
                     /gene="Alg3"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1027
                     /gene="Alg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1172
                     /gene="Alg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1421
                     /gene="Alg3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagtggtgca ctgtcaagat ggctgctggg ctgcggaaac gcggcctgcc gggttctgtc
       61 gtccagccgg caggaatctg gaaacaatgg ctacagcggg cctggcaaga acgctatcta
      121 ctgctgcggg agcctcgcta caccttgatg gtggcctcct gcctctgcct agcagaggtg
      181 ggcatcacct tctgggtcat tcacagggtg gcatacacag agattgactg gaaggcctac
      241 atggcccagg tggagggttt catcaatggc acatatgact acacacagct gcagggtgac
      301 accggacctc ttgtctaccc agctggtttt ctgtacatct ttacggggct ttactatgct
      361 acggaccggg gcactgacat ccctacggcc cagaacatct ttgctgtact ctaccttgtc
      421 accttggtgc ttgttttctt gatataccac cagacctcca aggtgcctcc cttcgtcttt
      481 ttcttcatgt gctgtgcctc ttaccgtgtc cactccatct ttgtgctgcg gctcttcaac
      541 gacccggtag ctatggcatt gctcttcctc agcgtcaacc tcttcctggc gcagcgctgg
      601 agctggggct gctgctgttt cagcctggcc gtctcggtga agatgaacgt gctccttttc
      661 gccccaggat tgctattcct tcttcttact cagttcggct tccgtggcgc cctccccaag
      721 ctggccctct gcgctgctct tcaggtggtg ctgggattgc ccttcctgtt agagaacccc
      781 gttggctacc tgtcgcgctc ctttgacctt ggccgtcagt ttctttacca atggacagtg
      841 aattggcgtc tcctgcctga agccatcttc ctgcaccgtg ccttccatct ggccctgctg
      901 gctgcccatc ttagcttcct cttgctattt gccctctgta ggtggcacag aacaggggaa
      961 agtattctgt cgctgctgaa ggatccttcc aaaaggaaag ttccacccca acccctcaca
     1021 cctaatcaga ttgtctccgt cctcttcacc tccaacttca ttggcgtctg cttcagccgc
     1081 tccctccact cccagtttta tgtctggtac ttccacacgc tgccccacct cctgtgggcc
     1141 acgcccgcac gctggctcac acacctgctc aggttgctgg tgctgggact catcgagctc
     1201 tcctggaata catacccatc cacacccttc agctctgctg ccctacacct gtgccacgct
     1261 gtcaccctgc tgcagctctg gctgtcccct cagttctttc ctaggagcgt ccagccaagc
     1321 aggaaaaccc actgaaatcc accccttcct tctaggactt gctcagcacc gtgggtggaa
     1381 tggactctgc tcttagaata aaccttgcaa gtccagctgt gaaaaaaaaa aaaaaaaaaa
     1441 aaaaa
//
