LOCUS       NM_001108104            2058 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus ALG12, alpha-1,6-mannosyltransferase (Alg12),
            mRNA.
ACCESSION   NM_001108104 XM_235555
VERSION     NM_001108104.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2058)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   2  (bases 1 to 2058)
  AUTHORS   Chantret I, Dupre T, Delenda C, Bucher S, Dancourt J, Barnier A,
            Charollais A, Heron D, Bader-Meunier B, Danos O, Seta N, Durand G,
            Oriol R, Codogno P and Moore SE.
  TITLE     Congenital disorders of glycosylation type Ig is defined by a
            deficiency in dolichyl-P-mannose:Man7GlcNAc2-PP-dolichyl
            mannosyltransferase
  JOURNAL   J Biol Chem 277 (28), 25815-25822 (2002)
   PUBMED   11983712
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM050024.1, BC161934.1 and BF409974.1.
            
            On Nov 29, 2008 this sequence version replaced NM_001108104.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161934.1, SRR8487226.233443.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 FM050024.1         1-2
            3-2034              BC161934.1         1-2032
            2035-2058           BF409974.1         1-24                c
FEATURES             Location/Qualifiers
     source          1..2058
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..2058
                     /gene="Alg12"
                     /note="ALG12, alpha-1,6-mannosyltransferase"
                     /db_xref="GeneID:315212"
                     /db_xref="RGD:1304826"
     exon            1..17
                     /gene="Alg12"
                     /inference="alignment:Splign:2.1.0"
     exon            18..205
                     /gene="Alg12"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..1507
                     /gene="Alg12"
                     /EC_number="2.4.1.260"
                     /note="alpha-1,6-mannosyltransferase ALG12;
                     asparagine-linked glycosylation 12 homolog (yeast,
                     alpha-1,6-mannosyltransferase);
                     dol-P-Man:Man(7)GlcNAc(2)-PP-Dol
                     alpha-1,6-mannosyltransferase; asparagine-linked
                     glycosylation 12, alpha-1,6-mannosyltransferase"
                     /codon_start=1
                     /product="dol-P-Man:Man(7)GlcNAc(2)-PP-Dol
                     alpha-1,6-mannosyltransferase precursor"
                     /protein_id="NP_001101574.2"
                     /db_xref="GeneID:315212"
                     /db_xref="RGD:1304826"
                     /translation="MAGKKSSGRQSLLPLGLLVTVAAIHLVACPYTKVEESFNLQATH
                     DLLYHQLDIDKYDHHEFPGVVPRTFLGPLLIAAFSSPVVYVLSLLEVSRFYSQLIVRG
                     VLGLGVIFGLWTLQKAVRQQFGATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLP
                     ALTAWLQHRWAVFVWLSAFVIIGFRAELAMLLGIMLLLTLYQRRMSVARLLQHAIPAG
                     ILCLGLTVAVDSYFWRYLVWPEGVVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCS
                     LLFIPLGAVDRRTFALALPSLGFVALYSLLPHKELRFIIYTFPVLNIMAARGCTYVLN
                     KKSWPYKVRALLVFGHVVVNVASTATSLYVSHFNYPGGVAMQRLHELVPPQTDVLVHI
                     DVAAAQTGVSRFLQVNDDWRYDKREDVQLGAAGMLDYTHIIMEAVPGHLALYRDTHRV
                     LARIEATTGVSLNLMKVPPFDVSLQTKLVLLERLLRPA"
     exon            206..338
                     /gene="Alg12"
                     /inference="alignment:Splign:2.1.0"
     exon            339..512
                     /gene="Alg12"
                     /inference="alignment:Splign:2.1.0"
     exon            513..707
                     /gene="Alg12"
                     /inference="alignment:Splign:2.1.0"
     exon            708..811
                     /gene="Alg12"
                     /inference="alignment:Splign:2.1.0"
     exon            812..1035
                     /gene="Alg12"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1199
                     /gene="Alg12"
                     /inference="alignment:Splign:2.1.0"
     exon            1200..1275
                     /gene="Alg12"
                     /inference="alignment:Splign:2.1.0"
     exon            1276..2040
                     /gene="Alg12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgcggatagc agaggaggtg catgaagttt aaagctcttc atggctggca agaaatcatc
       61 aggcaggcag tcactgctgc ctctggggct gttggtcact gtagctgcca tccaccttgt
      121 tgcctgtccg tacaccaagg tagaagagag cttcaacctg caggctacgc atgaccttct
      181 gtatcaccag ctggacatag acaagtatga ccaccatgag tttcctggag tcgttcccag
      241 gacattcctg gggccgctgt tgattgccgc gttctccagc cctgtggttt atgtgctttc
      301 actgttggaa gtctccagat tttattctca gctgatagtc agaggcgtcc ttggacttgg
      361 tgtgattttt ggactctgga cattacagaa ggcagtaaga cagcagttcg gggctacggt
      421 ggctgtcatg ttctgctgga tatcagccac acagtttcat ctcatgttct actgtacgag
      481 gacgcttccc aacgtgttgg ccctggctgt ggttttaccg gccctcacag cctggctgca
      541 gcacagatgg gccgtctttg tctggctctc cgcctttgtc atcattggct tcagggctga
      601 gctggctatg ctgctgggca tcatgctgct gctgaccttg taccaaagga ggatgtctgt
      661 ggccagattg ctccagcacg ccatcccagc agggattctt tgcctagggc tgacggttgc
      721 tgtggactcc tatttctggc gataccttgt gtggccagaa ggagtggtgc tttggtacaa
      781 cactgtcctg aacaaaagtt ccaactgggg tacctcccca ctcctgtggt atttctactc
      841 agccctgccc cgaggcctgg gctgcagcct tctcttcata cccctgggtg cagtggacag
      901 gagaaccttt gcgttggctc tgccaagcct tggattcgtg gctttatact cgctcctccc
      961 acacaaggaa ctgcggttca tcatctatac cttccctgta ctcaacatca tggctgccag
     1021 aggctgcacc tatgtcctga ataaaaagtc ttggccgtac aaggtgagag ctctgctggt
     1081 gtttggacat gtcgtggtaa atgtggcgtc tacagccaca tccctctatg tgtcccattt
     1141 caactaccct ggtggggttg cgatgcagcg gctacatgaa ctggtgccac ctcagacaga
     1201 tgtccttgta cacatcgatg tggctgctgc ccagacaggc gtgtcacggt ttctacaggt
     1261 caacgatgac tggaggtatg acaagaggga agatgtgcag ctgggagcag cgggcatgct
     1321 ggactacacc cacatcatca tggaggcagt gcctgggcac ctggccctct acagggacac
     1381 gcaccgagtc ctagcccgga ttgaggccac tacaggtgtg agcctgaatc taatgaaagt
     1441 gccgcccttt gatgtcagcc tgcagacaaa gctggtactt ctagagcggc tgcttaggcc
     1501 ggcctgagga caggagatct ggagcatcaa gtgtggtcac cacctaactc agtaaagaca
     1561 ggaaaacagc acaggccagg gacttccagt aacccccggc gttgccctgc agcaggctgg
     1621 gccaggccct acaacagcca cacctgagac acagggccga gaatgtggag ccaccaccaa
     1681 gtgtgataat ggcctgttca aacctgtctg ccatggttag gtgacccaca ggagtgttta
     1741 tattcattct gggagccatt cagaaccaag aggacaatga gtcaggctag aacgccctgc
     1801 caccctgctc tgcagtgacc ccactatatg tttcttgccc ctgaaccaca cttgttgccc
     1861 atggcctcag gagacgacga tgtaaaacca ggtctttaca gattagacac acacacacac
     1921 accaccaatc atggcagctg ttatagtccg aggcatgcta cctccatttc ggattagttc
     1981 tgaggacata acacgttttc ataaaagaac agaaataaaa attatgttat attatgtctt
     2041 aaaaaaaaaa aaaaaaaa
//
