LOCUS       NM_001008342            1375 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus aldo-keto reductase family 1, member E2 (Akr1e2),
            mRNA.
ACCESSION   NM_001008342 XM_225536
VERSION     NM_001008342.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1375)
  AUTHORS   Azuma,Y., Nishinaka,T., Ushijima,S., Soh,J., Katsuyama,M., Lu,H.P.,
            Kawata,M., Yabe-Nishimura,C. and Miki,T.
  TITLE     Characterization of htAKR, a novel gene product in the aldo-keto
            reductase family specifically expressed in human testis
  JOURNAL   Mol Hum Reprod 10 (7), 527-533 (2004)
   PUBMED   15118078
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086397.1.
            
            On Dec 16, 2004 this sequence version replaced XM_225536.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086397.1, FQ212583.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132308, SAMEA5756307
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1375
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.2"
     gene            1..1375
                     /gene="Akr1e2"
                     /gene_synonym="Akr1cl2; Akr1e1"
                     /note="aldo-keto reductase family 1, member E2"
                     /db_xref="GeneID:307091"
                     /db_xref="RGD:1309599"
     exon            1..106
                     /gene="Akr1e2"
                     /gene_synonym="Akr1cl2; Akr1e1"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..973
                     /gene="Akr1e2"
                     /gene_synonym="Akr1cl2; Akr1e1"
                     /EC_number="1.1.1.263"
                     /note="AF reductase; aldo-keto reductase family 1 member
                     C-like protein 2; aldo-keto reductase family 1, member E1;
                     aldo-keto reductase family 1, member C-like 2"
                     /codon_start=1
                     /product="1,5-anhydro-D-fructose reductase"
                     /protein_id="NP_001008343.1"
                     /db_xref="GeneID:307091"
                     /db_xref="RGD:1309599"
                     /translation="MHQIPTVGLGTWKASPGEVTDAVKVAINLGYRHFDCAYLYHNES
                     EVGMGIKEKIKEGVVKRDELFIVSKLWCTYHKQSLVKTACINTLEALNLDYLDLYLIH
                     WPMGFKPGDKDIPLDRSGKVIPSHTSFLDTWEAMEDLVIEGLVKNIGVSNFNHEQLDR
                     LLNKPGLRIKPITNQIECHPYLNQKSLIDFCHGRNVSVTAYRPLGGSRDGVHLMDDIV
                     IRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVNPSRIRENIQVFDFELTEKDMEELLS
                     LDKNLRLATFPSTENHKDYPFHIEY"
     exon            107..274
                     /gene="Akr1e2"
                     /gene_synonym="Akr1cl2; Akr1e1"
                     /inference="alignment:Splign:2.1.0"
     exon            275..391
                     /gene="Akr1e2"
                     /gene_synonym="Akr1cl2; Akr1e1"
                     /inference="alignment:Splign:2.1.0"
     exon            392..469
                     /gene="Akr1e2"
                     /gene_synonym="Akr1cl2; Akr1e1"
                     /inference="alignment:Splign:2.1.0"
     exon            470..592
                     /gene="Akr1e2"
                     /gene_synonym="Akr1cl2; Akr1e1"
                     /inference="alignment:Splign:2.1.0"
     exon            593..690
                     /gene="Akr1e2"
                     /gene_synonym="Akr1cl2; Akr1e1"
                     /inference="alignment:Splign:2.1.0"
     exon            691..763
                     /gene="Akr1e2"
                     /gene_synonym="Akr1cl2; Akr1e1"
                     /inference="alignment:Splign:2.1.0"
     exon            764..847
                     /gene="Akr1e2"
                     /gene_synonym="Akr1cl2; Akr1e1"
                     /inference="alignment:Splign:2.1.0"
     exon            848..930
                     /gene="Akr1e2"
                     /gene_synonym="Akr1cl2; Akr1e1"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1346
                     /gene="Akr1e2"
                     /gene_synonym="Akr1cl2; Akr1e1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcccggggc tgctcgccgt cacctccagt gcaggttggg ggctgatcct ctgagcgaag
       61 gggagccatg catcaaatcc ccacagtggg cctgggcacc tggaaggcct ctccaggaga
      121 agtgaccgat gcggttaagg tggctatcaa cctgggctac cggcacttcg actgtgctta
      181 cttataccac aatgagagtg aggttgggat gggaatcaag gagaaaatca aggagggtgt
      241 ggtgaagaga gacgagctgt tcatcgtcag taagctgtgg tgcacgtacc acaagcagtc
      301 tttggtgaaa acggcatgca tcaataccct ggaggcctta aacctggatt acctggacct
      361 ctacctcata cactggccca tgggcttcaa gcctggggac aaagatatcc ctttggatcg
      421 cagtggcaag gtcataccca gtcacaccag ctttctggac acttgggagg ccatggagga
      481 cctggtgatt gagggtctgg tgaagaacat tggggtgtcc aacttcaacc atgaacagct
      541 tgacagactt ttgaataagc ctggtttgag aatcaagcca ataactaacc agattgaatg
      601 ccacccatat cttaatcaaa agagcctaat tgatttttgc catggaagaa atgtgtctgt
      661 gaccgcttac cgtcccctcg gtggctcaag agatggggtt cacttgatgg atgatatcgt
      721 tattcggaag attgcaaaga agcatgggaa gtctcctgct cagattttga tccgatttca
      781 gatccaaagg aacttgatag tgattcccaa atctgtcaac ccaagtcgga ttagagagaa
      841 tattcaggta tttgattttg aattaactga aaaagatatg gaggaacttc tcagcctcga
      901 caagaacctc cgcttggcca ccttcccctc aactgaaaat cataaggact atcctttcca
      961 catagagtac taaagacagc ctcactctcc gtcatttctg cccagtggaa acagatctcc
     1021 agggtcagca gcactgatcc acctctgcag aggctgtgtg gtccctgcgt ggccacagca
     1081 acagacgcag ccacagccaa gaatgacaac agagtcggaa caaggaaaac tctgcctaga
     1141 acagaaccag ttcggagaaa aataaagatc tagggatgag aaagggaggt accacaaggc
     1201 gtgtggctgc ttccaagttg ttatggaaag ccaagcgcca agaataatgt aatttatgtc
     1261 agttagccct agtccttgtg gcttctattc taggaagcga gatgctgatt gctcatgaat
     1321 taaagttacc ttcacatttt aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//
