LOCUS       NM_001135744            1292 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus aldo-keto reductase family 1, member C12-like 1
            (Akr1c12l1), mRNA.
ACCESSION   NM_001135744 XM_001068266 XM_574075
VERSION     NM_001135744.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1292)
  AUTHORS   Sanai,M., Endo,S., Matsunaga,T., Ishikura,S., Tajima,K.,
            El-Kabbani,O. and Hara,A.
  TITLE     Rat NAD+-dependent 3alpha-hydroxysteroid dehydrogenase (AKR1C17): a
            member of the aldo-keto reductase family highly expressed in kidney
            cytosol
  JOURNAL   Arch Biochem Biophys 464 (1), 122-129 (2007)
   PUBMED   17475203
  REMARK    GeneRIF: AKR1C17 is a member of the aldo-keto reductase family
            highly expressed in kidney cytosol.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC129122.1.
            
            On or before Oct 11, 2008 this sequence version replaced
            XM_001068266.1, XM_574075.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC129122.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1292
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.2"
     gene            1..1292
                     /gene="Akr1c12l1"
                     /gene_synonym="Akr1c17; RGD1559604"
                     /note="aldo-keto reductase family 1, member C12-like 1"
                     /db_xref="GeneID:498790"
                     /db_xref="RGD:1559604"
     exon            1..111
                     /gene="Akr1c12l1"
                     /gene_synonym="Akr1c17; RGD1559604"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..999
                     /gene="Akr1c12l1"
                     /gene_synonym="Akr1c17; RGD1559604"
                     /codon_start=1
                     /product="aldo-keto reductase family 1, member C12-like 1"
                     /protein_id="NP_001129216.1"
                     /db_xref="GeneID:498790"
                     /db_xref="RGD:1559604"
                     /translation="MSSKHHCVKLNDGHFIPALGFGTSIPNEVPKSKSLEAVHLAIDA
                     GYHHIDTASAYQIEEEIGQAIQSKIKAGVVKREDMFITTKLWCTCFRPELVKPALEKS
                     LKNLQLDYADLYIMHYPVPMKSGDKYLPVDDKGKWLLDTVDFCDTWEMLEKCKDAGLV
                     KSIGVSNFNHKQLERLLNKPGLKYKPVCNQVECHLYMNQSKLLDYCKSKDIVLVAYGA
                     LGTQRYKEWVDQNSPVLLDDPVLCDVAKKNKRSPALIALRYLVQREVVPLAQSFKENE
                     MRENLQVFEFQLSPEDMKTLDGLNKNFRYLSAEFLAGHPEYPFSEEY"
     exon            112..279
                     /gene="Akr1c12l1"
                     /gene_synonym="Akr1c17; RGD1559604"
                     /inference="alignment:Splign:2.1.0"
     exon            280..396
                     /gene="Akr1c12l1"
                     /gene_synonym="Akr1c17; RGD1559604"
                     /inference="alignment:Splign:2.1.0"
     exon            397..474
                     /gene="Akr1c12l1"
                     /gene_synonym="Akr1c17; RGD1559604"
                     /inference="alignment:Splign:2.1.0"
     exon            475..597
                     /gene="Akr1c12l1"
                     /gene_synonym="Akr1c17; RGD1559604"
                     /inference="alignment:Splign:2.1.0"
     exon            598..707
                     /gene="Akr1c12l1"
                     /gene_synonym="Akr1c17; RGD1559604"
                     /inference="alignment:Splign:2.1.0"
     exon            708..873
                     /gene="Akr1c12l1"
                     /gene_synonym="Akr1c17; RGD1559604"
                     /inference="alignment:Splign:2.1.0"
     exon            874..956
                     /gene="Akr1c12l1"
                     /gene_synonym="Akr1c17; RGD1559604"
                     /inference="alignment:Splign:2.1.0"
     exon            957..1215
                     /gene="Akr1c12l1"
                     /gene_synonym="Akr1c17; RGD1559604"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacgcttagg caggggaggg agagacaatg agttccaaac atcactgtgt caaactaaac
       61 gatggccact tcattcctgc cctgggcttt ggcaccagta tacccaacga ggttcccaag
      121 agtaagtcac tggaggctgt acacctggct atagatgctg ggtaccacca tattgatacg
      181 gcctctgcat accaaataga agaggagata ggacaggcca ttcaaagcaa gattaaagct
      241 ggggttgtaa agagagaaga tatgttcatc actacaaagc tttggtgtac ttgctttcga
      301 ccagagctgg tcaagcctgc tttggaaaaa tcactgaaaa atcttcaact ggattatgcc
      361 gatctttaca ttatgcatta cccagtgcca atgaagtcag gggataaata tcttccagta
      421 gatgacaaag gaaaatggct attggacact gtggatttct gtgacacatg ggagatgttg
      481 gagaagtgta aggatgcagg gttggtcaag tccattgggg tgtccaactt taaccacaag
      541 cagctggagc gactcctaaa caagccagga ctgaagtaca aacctgtctg caaccaggtt
      601 gaatgtcatc tttatatgaa ccagagtaag ctactggact actgcaagtc aaaagacatt
      661 gttctcgttg cttatggtgc tctgggaacc caacgatata aagaatgggt ggaccagaat
      721 tccccagttc tcttggatga tccagttctt tgtgatgtgg ctaaaaagaa caagcgaagc
      781 cctgccctga ttgcccttcg atacctggtt cagcgtgagg tggtgcccct tgcccagagt
      841 ttcaaagaga atgagatgag agagaatttg caggtttttg aatttcagtt gtctcctgag
      901 gacatgaaaa cactagatgg cctgaacaaa aattttcgat atctttcagc agagtttctt
      961 gctggccacc cagaatatcc attttcagaa gaatattaac atggggagct aattatgatt
     1021 tctgcctgac atccctgtat atggacagtg atgctgatga tgtagcctag atgctgctgg
     1081 atggacatat tgcttcagat caacctggac ggctcagcaa ctcacattca actgaagctc
     1141 cagctaatgg actcaaagaa aaggaaaata attttgatga tgccttgaaa tataaaattt
     1201 tctcttcaaa aattaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1261 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
