LOCUS       NM_001013946            2194 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus A-kinase anchoring protein 8 like (Akap8l), mRNA.
ACCESSION   NM_001013946 XM_216820
VERSION     NM_001013946.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2194)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 2194)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 2194)
  AUTHORS   Kvissel AK, Orstavik S, Eikvar S, Brede G, Jahnsen T, Collas P,
            Akusjarvi G and Skalhegg BS.
  TITLE     Involvement of the catalytic subunit of protein kinase A and of
            HA95 in pre-mRNA splicing
  JOURNAL   Exp Cell Res 313 (13), 2795-2809 (2007)
   PUBMED   17594903
REFERENCE   4  (bases 1 to 2194)
  AUTHORS   Li Y, Kao GD, Garcia BA, Shabanowitz J, Hunt DF, Qin J, Phelan C
            and Lazar MA.
  TITLE     A novel histone deacetylase pathway regulates mitosis by modulating
            Aurora B kinase activity
  JOURNAL   Genes Dev 20 (18), 2566-2579 (2006)
   PUBMED   16980585
REFERENCE   5  (bases 1 to 2194)
  AUTHORS   Sayer JA, Manczak M, Akileswaran L, Reddy PH and Coghlan VM.
  TITLE     Interaction of the nuclear matrix protein NAKAP with HypA and
            huntingtin: implications for nuclear toxicity in Huntington's
            disease pathogenesis
  JOURNAL   Neuromolecular Med 7 (4), 297-310 (2005)
   PUBMED   16391387
REFERENCE   6  (bases 1 to 2194)
  AUTHORS   Han I, Xue Y, Harada S, Orstavik S, Skalhegg B and Kieff E.
  TITLE     Protein kinase A associates with HA95 and affects transcriptional
            coactivation by Epstein-Barr virus nuclear proteins
  JOURNAL   Mol Cell Biol 22 (7), 2136-2146 (2002)
   PUBMED   11884601
REFERENCE   7  (bases 1 to 2194)
  AUTHORS   Yang JP, Tang H, Reddy TR and Wong-Staal F.
  TITLE     Mapping the functional domains of HAP95, a protein that binds RNA
            helicase A and activates the constitutive transport element of type
            D retroviruses
  JOURNAL   J Biol Chem 276 (33), 30694-30700 (2001)
   PUBMED   11402034
REFERENCE   8  (bases 1 to 2194)
  AUTHORS   Martins SB, Eide T, Steen RL, Jahnsen T, Skalhegg B S and Collas P.
  TITLE     HA95 is a protein of the chromatin and nuclear matrix regulating
            nuclear envelope dynamics
  JOURNAL   J Cell Sci 113 Pt 21, 3703-3713 (2000)
   PUBMED   11034899
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085785.1.
            
            On Apr 20, 2005 this sequence version replaced XM_216820.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085785.1, SRR8487226.218535.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2194
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..2194
                     /gene="Akap8l"
                     /note="A-kinase anchoring protein 8 like"
                     /db_xref="GeneID:299569"
                     /db_xref="RGD:1359200"
     exon            1..97
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..2010
                     /gene="Akap8l"
                     /note="A kinase (PRKA) anchor protein 8-like"
                     /codon_start=1
                     /product="A-kinase anchor protein 8-like"
                     /protein_id="NP_001013968.1"
                     /db_xref="GeneID:299569"
                     /db_xref="RGD:1359200"
                     /translation="MSYTGFVQGSETTLQSTYCDTSAQPTCDYGYGTWNSGTNRGYEN
                     YGYGYGYGQDNTTNYGYGMATSHSWEMANSDTNANPSASGSASADSVLSRINQRLDMM
                     PHLETDMIQGGVYGSGGGERYDSYEACDSRAILSERDLYRSSYDYGELDPEMEMAYEG
                     QYDAYRDQFRMRGGDTFGPRAQGWARDARSGRPMASGYGRMWEDPMGARGQCMPGASR
                     LPSLFSQNIIPEYGMFQGMRGGGAFSGGSRFGFGFGNGMKQMRRTWKTWTTADFRTKK
                     KKRKQGGSPDEPDCKATRTDCSDNSDSDNDEGTEGEAAEGAESAEALEKGSRAEGEDE
                     EGKEDGREEGKEDLEKGALTAQDESSQAKRKLQASKKSQDKQKKRQRDRMVERIQFVC
                     SLCKYRTFYEDEMGSHLDSKFHKEHFKYVGTKLPKQTADFLQDYVTNKTKKTEELRKT
                     VEDLDGLIQQIYRDQDLTQEIAMEHFVKKVEAAHCAACDLFIPMQFGIIQKHLKTMDH
                     NRNRRLMMEQSKKSSLMVARSILNNKLISKKLERYLKGENPFTDNPEEEKEQDEVEAG
                     ALEEGAPSEATGLTEGVSVQPPVPLEPTPGTATPPPPPPPEEENPVPLLGGALQCQIR
                     GIPGLDVEDDEEGGGGP"
     exon            98..172
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     exon            173..205
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     exon            206..449
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     exon            450..903
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1000
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1071
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1135
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1244
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1386
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     exon            1387..1492
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     exon            1493..1623
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     exon            1624..1719
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
     exon            1720..2077
                     /gene="Akap8l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgtggaagg accccaggga ttgttgtggc gtcagacgcg cagagtagcg gtctgtgtcc
       61 aaggctcggg tgttctctgc ggccatgagc tacacaggct ttgtccaagg atccgaaacc
      121 actttgcagt ctacctactg tgacaccagt gcccagccca cctgtgatta tggatatgga
      181 acttggaact ctgggacaaa tagaggctac gagaactatg gttatggcta tggctatggc
      241 caggataaca ccaccaacta tgggtatggt atggccactt cacactcttg ggaaatggct
      301 aactctgaca caaatgcaaa ccctagtgcc tcgggtagcg ccagtgccga ttccgtttta
      361 tccagaatta accagcgctt agatatgatg ccacacttgg agacagacat gatacaagga
      421 ggtgtgtacg gctcaggtgg tggagaaaga tatgattcct atgaggcctg tgactcaagg
      481 gccatcctga gtgaacgaga cctctaccgg tcgagctatg actatggcga gcttgaccct
      541 gagatggaaa tggcctatga gggtcaatat gatgcctacc gtgaccagtt tcgaatgcgt
      601 ggaggagata catttggtcc aagggctcag ggctgggccc gggatgcccg gagtggacgg
      661 ccaatggcct cgggctatgg gcgcatgtgg gaagacccca tgggggcccg gggccagtgc
      721 atgcctggtg cctcccggct gccctccctc ttctcccaga acatcatacc cgagtatggc
      781 atgttccagg gcatgcgtgg tgggggtgcc ttctctggtg gctcccgatt tggcttcgga
      841 tttggcaatg gcatgaagca gatgaggcgg acctggaaga cctggaccac agcggacttc
      901 cggaccaaaa agaagaagag aaagcagggt ggcagtcctg atgagccaga ctgcaaggct
      961 accagaacag actgctcaga caacagtgac tcagacaacg atgaaggtac tgagggggaa
     1021 gctgcagagg gtgctgaaag tgctgaggct ctggagaaag gctcccgagc agaaggagag
     1081 gacgaggagg gaaaagaaga tgggagagaa gaaggcaaag aagatttgga gaaaggggcc
     1141 ctgaccgccc aggatgagag cagccaggcc aagcgcaagt tgcaggcaag caagaagagc
     1201 caagacaaac agaaaaagcg gcagcgggac cgtatggtgg aaaggatcca gtttgtctgt
     1261 tctctctgca aataccggac cttctatgaa gacgagatgg gtagccacct tgatagcaag
     1321 ttccacaagg aacacttcaa atatgtaggc accaagcttc ccaagcagac agctgacttt
     1381 ctgcaggact atgtcaccaa caagaccaag aagacagagg agctccgaaa aactgtagag
     1441 gaccttgatg gtctgatcca acaaatctac agagaccaag atctgaccca agaaattgct
     1501 atggagcatt ttgtgaagaa ggtggaggcg gcccattgtg cagcctgtga ccttttcatc
     1561 cccatgcagt ttggaatcat ccaaaagcat ctcaagacta tggatcacaa ccgaaaccgc
     1621 aggctcatga tggagcagtc caagaagtcc tcgcttatgg tggcacgcag tattctgaac
     1681 aacaagctca ttagcaagaa gctggagcga tatcttaagg gcgagaatcc ttttactgac
     1741 aacccggagg aggagaagga acaagacgag gtggaggctg gcgctctgga agaaggggca
     1801 ccaagcgaag cgacagggct cacagaaggc gtgtcggtcc agcccccggt gcccctggag
     1861 cccaccccgg ggactgcaac accgccacct ccgccaccac cagaggagga gaacccagta
     1921 cccttgctgg gcggggcgct acagtgccag atccgcggga tcccggggct cgacgtagaa
     1981 gacgacgagg agggcggtgg gggtccttaa cccttaccgg gcacggctcg cgtagccgag
     2041 gctggaaatc cagcctaata aagtgctttc ccaccgaaaa aaaaaaaaaa aaaaaaaaaa
     2101 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2161 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
