LOCUS       NM_001004266            1581 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Rattus norvegicus adenylate kinase 8 (Ak8), mRNA.
ACCESSION   NM_001004266 XM_231110
VERSION     NM_001004266.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1581)
  AUTHORS   Vadnais,M.L., Cao,W., Aghajanian,H.K., Haig-Ladewig,L., Lin,A.M.,
            Al-Alao,O. and Gerton,G.L.
  TITLE     Adenine nucleotide metabolism and a role for AMP in modulating
            flagellar waveforms in mouse sperm
  JOURNAL   Biol Reprod 90 (6), 128 (2014)
   PUBMED   24740601
REFERENCE   2  (bases 1 to 1581)
  AUTHORS   Amiri,M., Conserva,F., Panayiotou,C., Karlsson,A. and Solaroli,N.
  TITLE     The human adenylate kinase 9 is a nucleoside mono- and diphosphate
            kinase
  JOURNAL   Int J Biochem Cell Biol 45 (5), 925-931 (2013)
   PUBMED   23416111
REFERENCE   3  (bases 1 to 1581)
  AUTHORS   Vogel,P., Read,R.W., Hansen,G.M., Payne,B.J., Small,D., Sands,A.T.
            and Zambrowicz,B.P.
  TITLE     Congenital hydrocephalus in genetically engineered mice
  JOURNAL   Vet Pathol 49 (1), 166-181 (2012)
   PUBMED   21746835
REFERENCE   4  (bases 1 to 1581)
  AUTHORS   Panayiotou,C., Solaroli,N., Xu,Y., Johansson,M. and Karlsson,A.
  TITLE     The characterization of human adenylate kinases 7 and 8
            demonstrates differences in kinetic parameters and structural
            organization among the family of adenylate kinase isoenzymes
  JOURNAL   Biochem J 433 (3), 527-534 (2011)
   PUBMED   21080915
REFERENCE   5  (bases 1 to 1581)
  AUTHORS   Van Rompay,A.R., Johansson,M. and Karlsson,A.
  TITLE     Identification of a novel human adenylate kinase. cDNA cloning,
            expression analysis, chromosome localization and characterization
            of the recombinant protein
  JOURNAL   Eur J Biochem 261 (2), 509-517 (1999)
   PUBMED   10215863
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079446.1.
            
            On Sep 10, 2004 this sequence version replaced XM_231110.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079446.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1581
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..1581
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /note="adenylate kinase 8"
                     /db_xref="GeneID:311833"
                     /db_xref="RGD:1303144"
     exon            1..100
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..1456
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /EC_number="2.7.4.3"
                     /EC_number="2.7.4.6"
                     /note="putative adenylate kinase-like protein C9orf98
                     homolog; HypB, AroK, ADK and rho factor domain containing
                     protein RGD1303144; ATP-AMP transphosphorylase 8"
                     /codon_start=1
                     /product="adenylate kinase 8"
                     /protein_id="NP_001004266.1"
                     /db_xref="GeneID:311833"
                     /db_xref="RGD:1303144"
                     /translation="MDATSAPHRIPPEMPQYGEDYHIFEMMQSMLEQLLIHQPEDPIS
                     FMISHLRRNNDNVPRVVILGPPASGKTTIAMWLCKHLNSNLITKENLLEREFSLLSLE
                     AKKHYQVYKRVPNSTLVSLVQERLNEDDCLRRGWILDGIPERREQALMIQTLGLAPKH
                     VIVLSAPDSVLIERNVGKRIDPVTGEIYHTTFDWPPELEIQNRLIQPEGISEIDTAKK
                     LLEYHRHIIRILPSYPKILKTISSDQPCVDVFYQALTYVQSGHRCNAPFTPKVLLCGP
                     MGCGKKLQAALLSQKYGLVNISCGQLLKEAMAAESSLGDLIEPFFEKRMTVPDSIITR
                     VLTERLKQQDCIQKGWVLHGFPRDLDQARLLNSMGYSPNRVFFLNVPLDSILERLTLR
                     RTDPVTGERFHLMYKPPPTIEVQARLLQNPKDSEEYIKLQTDLFYRNSGDLEQYYDRA
                     IIVNGDQDPYTVFEYIESGIINPLPRKVT"
     exon            101..185
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
     exon            186..235
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
     exon            236..349
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
     exon            350..418
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
     exon            419..500
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
     exon            501..572
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
     exon            573..773
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
     exon            774..905
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
     exon            906..995
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
     exon            996..1137
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1218
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1551
                     /gene="Ak8"
                     /gene_synonym="AK 8; RGD1303144"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctcgttgtc cgaaacatgg atgctacctc ggccccgcac cgcatccccc cagaaatgcc
       61 tcagtacggg gaagactacc acatcttcga gatgatgcag agcatgctgg agcagctcct
      121 gattcaccag ccagaggacc ccatcagctt catgatcagt caccttcgca ggaacaacga
      181 taatgtgccg agagttgtga tattaggtcc gcctgcctca gggaaaacca ccatcgcgat
      241 gtggctctgc aaacatctga acagcaacct catcaccaag gagaacttat tagagagaga
      301 gttttccctc ctgtctctgg aagccaagaa acactaccag gtttacaaga gagtgcccaa
      361 ttcgactctt gtcagcctgg tccaggagcg tctgaatgag gatgactgcc tcagaagggg
      421 ctggatcctg gatggcatcc ccgagaggcg ggagcaggct ctgatgatcc agaccctggg
      481 actggcaccc aagcacgtca tcgtgcttag cgctccagac tccgtcctga tcgagagaaa
      541 tgtggggaaa cggattgatc ctgtcactgg agagatctat cacaccacct tcgactggcc
      601 ccctgagctt gaaatacaga acaggctgat acagccagaa ggcatctcgg agatagacac
      661 agcgaagaag ctgctggaat accacaggca catcatcagg attcttcctt cctaccctaa
      721 aatcctgaaa actatcagct cagaccagcc atgtgtggat gtcttctacc aggctctgac
      781 ctacgtccaa tctggccacc gatgtaatgc cccgttcacc cccaaggtgc tgctgtgtgg
      841 gccaatgggc tgtgggaaga aactgcaggc tgcccttctg tcccagaaat atggcctcgt
      901 gaacatcagc tgcgggcagc tgctgaagga agctatggca gccgaatcga gccttgggga
      961 cctcatagaa ccattctttg aaaagaggat gacagttcca gacagtatca tcaccagagt
     1021 tctgactgag cgtctgaagc aacaagattg catccagaaa gggtgggtgc tgcacggctt
     1081 cccaagagac ctggaccagg cccggctgct gaactctatg ggctacagtc ccaacagggt
     1141 gttcttcctg aatgtgccgt tggattccat cctggagcgg ctcacactga gaaggacaga
     1201 ccctgtcaca ggagaaaggt tccatctcat gtacaagccc cctcccacca tagaggtcca
     1261 ggctcgcctc ctgcagaacc ccaaggattc agaggagtac atcaagctcc aaacggactt
     1321 gttctatagg aactctgggg acctggagca gtactacgat cgggccatca ttgtcaacgg
     1381 tgaccaggac ccatacacag tttttgagta tatagagagt ggaatcatta atcctctgcc
     1441 caggaaagtt acctgatatg tggggagcca ggaacaagcc ccaaagacac tcaaatcccc
     1501 tgccctcaac cttcatcaga ccccacccag ccaataaaga tgctagtcac aaaaaaaaaa
     1561 aaaaaaaaaa aaaaaaaaaa a
//
