LOCUS       NM_001108055            2913 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus adenylate kinase 7 (Ak7), mRNA.
ACCESSION   NM_001108055 XM_001069409 XM_234507
VERSION     NM_001108055.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2913)
  AUTHORS   Amiri,M., Conserva,F., Panayiotou,C., Karlsson,A. and Solaroli,N.
  TITLE     The human adenylate kinase 9 is a nucleoside mono- and diphosphate
            kinase
  JOURNAL   Int J Biochem Cell Biol 45 (5), 925-931 (2013)
   PUBMED   23416111
REFERENCE   2  (bases 1 to 2913)
  AUTHORS   Vogel,P., Read,R.W., Hansen,G.M., Payne,B.J., Small,D., Sands,A.T.
            and Zambrowicz,B.P.
  TITLE     Congenital hydrocephalus in genetically engineered mice
  JOURNAL   Vet Pathol 49 (1), 166-181 (2012)
   PUBMED   21746835
REFERENCE   3  (bases 1 to 2913)
  AUTHORS   Panayiotou,C., Solaroli,N., Xu,Y., Johansson,M. and Karlsson,A.
  TITLE     The characterization of human adenylate kinases 7 and 8
            demonstrates differences in kinetic parameters and structural
            organization among the family of adenylate kinase isoenzymes
  JOURNAL   Biochem J 433 (3), 527-534 (2011)
   PUBMED   21080915
REFERENCE   4  (bases 1 to 2913)
  AUTHORS   Fernandez-Gonzalez,A., Kourembanas,S., Wyatt,T.A. and
            Mitsialis,S.A.
  TITLE     Mutation of murine adenylate kinase 7 underlies a primary ciliary
            dyskinesia phenotype
  JOURNAL   Am J Respir Cell Mol Biol 40 (3), 305-313 (2009)
   PUBMED   18776131
REFERENCE   5  (bases 1 to 2913)
  AUTHORS   Van Rompay,A.R., Johansson,M. and Karlsson,A.
  TITLE     Identification of a novel human adenylate kinase. cDNA cloning,
            expression analysis, chromosome localization and characterization
            of the recombinant protein
  JOURNAL   Eur J Biochem 261 (2), 509-517 (1999)
   PUBMED   10215863
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Oct 12, 2012 this sequence version replaced NM_001108055.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.933691.1,
                                           SRR26643293.37139.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-227               JAXUCZ010000006.1  130376604-130376830
            228-425             JAXUCZ010000006.1  130379657-130379854
            426-534             JAXUCZ010000006.1  130383753-130383861
            535-629             JAXUCZ010000006.1  130388715-130388809
            630-740             JAXUCZ010000006.1  130399087-130399197
            741-821             JAXUCZ010000006.1  130405766-130405846
            822-910             JAXUCZ010000006.1  130407314-130407402
            911-1001            JAXUCZ010000006.1  130409238-130409328
            1002-1079           JAXUCZ010000006.1  130411277-130411354
            1080-1229           JAXUCZ010000006.1  130412408-130412557
            1230-1358           JAXUCZ010000006.1  130414955-130415083
            1359-1485           JAXUCZ010000006.1  130415776-130415902
            1486-1614           JAXUCZ010000006.1  130423871-130423999
            1615-1683           JAXUCZ010000006.1  130426613-130426681
            1684-1881           JAXUCZ010000006.1  130429057-130429254
            1882-2102           JAXUCZ010000006.1  130432635-130432855
            2103-2261           JAXUCZ010000006.1  130443105-130443263
            2262-2913           JAXUCZ010000006.1  130444015-130444666
FEATURES             Location/Qualifiers
     source          1..2913
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..2913
                     /gene="Ak7"
                     /note="adenylate kinase 7"
                     /db_xref="GeneID:314416"
                     /db_xref="RGD:1309600"
     exon            1..227
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     CDS             126..2300
                     /gene="Ak7"
                     /EC_number="2.7.4.3"
                     /note="putative adenylate kinase 7"
                     /codon_start=1
                     /product="adenylate kinase 7"
                     /protein_id="NP_001101525.2"
                     /db_xref="GeneID:314416"
                     /db_xref="RGD:1309600"
                     /translation="MAEEEVPATTEKVLKIQRVFINHLDTYSSGNIGKFLANCVAGAS
                     LEEIGEEEEEEDETKSAGAATEATTTKVKEGTFQIVGTLAKLESTRPDFAVETYSHGT
                     SREDLLARLLECDVVVYNITENAQQVQEALWAVSALSEEISHFEKRKMFILLSTVMTW
                     ARSKPLDPDDSEVPFTEEDYRRRKHHPNFQDHINAEKLVLKFGKNAKKFVTYVVASGL
                     QYGVEGGILHAFFKMAWLGEIPALPVFGDGSNCIPAIHVLDLAGVIQNVIDHVPKLHY
                     LVAVDESVHTLEDLVKCISKNTGPGKIQKVPKENAFLTKDLTQEHLDQLLVNLRMEAL
                     FVKENFNIRWAAQTGFVENIGSILKEYKQSRGLLPIKICILGPPAVGKSSISGELVKY
                     YKLHHIKIKDVISEAIAKLEAIVAPKESTEEEEGEEEEEEENVEDAQELLDGIKESME
                     QNAGRLEDQYVIRFVKEKLKSMPCKNQGYVLDGFPKTYDQAKDLFNQEDEEEEEEVRG
                     KMFPYDKLITPEFVCNLDASDEFLKERVMNLPESVVAGTHYSQDRFLRALSNYRDINT
                     DDETVFNYFDEIEIHPIHIDVGKLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEVEK
                     KAAEERLAKEAAQTAEREHKEALEMAEKIARWEEWSKRLEEVKREERELLEAQSIPLR
                     NYLMTYVMPTLMQGLNECCKVRPEDPVDFLAEYLFKNNPEMQ"
     exon            228..425
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            426..534
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            535..629
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            630..740
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            741..821
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            822..910
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1001
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1079
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1229
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1358
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1485
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            1486..1614
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1683
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            1684..1881
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            1882..2102
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            2103..2261
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
     exon            2262..2913
                     /gene="Ak7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acgccccacc cagagcctga gccacagccc agggagcctg accttttcag ccttccaaag
       61 cccagcctct cctacttagc aaccgacagg actctttcac cttagcaact actacagctt
      121 ccaccatggc tgaagaggaa gttcctgcga cgaccgaaaa agttctgaaa atacagaggg
      181 tgttcataaa ccatctggac acctatagca gcggaaacat aggaaagttc ctagctaact
      241 gtgtcgccgg ggcttcactg gaagagattg gagaagagga agaggaagag gatgagacca
      301 agtcagcggg agctgctaca gaagctacca ccacaaaagt gaaggaaggc accttccaga
      361 ttgtgggcac cttagccaag ctggagagca ccaggccgga cttcgctgtg gaaacctact
      421 cccatggcac ctcccgggag gacctgctcg cgcgtctctt ggagtgtgac gttgtcgtct
      481 ataacatcac ggagaatgca cagcaagtgc aggaagcctt gtgggcagtc tccgcactga
      541 gtgaagaaat cagccatttt gaaaagcgaa agatgttcat tttgttgtcg acagtgatga
      601 catgggcgag atccaaaccc ctggaccctg atgatagcga ggttcccttc accgaagagg
      661 attatcggcg aaggaaacat caccccaact tccaggacca catcaacgcc gaaaaactag
      721 tcctcaagtt tggaaagaat gccaaaaagt ttgtaactta tgtagtcgcc tcaggacttc
      781 agtatggagt ggaaggaggc atcttacacg cattttttaa gatggcctgg ctcggagaga
      841 ttcctgcatt accggtgttt ggagacggga gcaattgcat tccagccatt cacgttcttg
      901 acctagcagg agtgatccag aacgtcatag accacgtgcc taagcttcac tacctggtgg
      961 ctgtggacga gtctgtccac accctggaag acctggtcaa gtgcatcagc aaaaataccg
     1021 gccctggaaa aatccagaaa gtacccaaag aaaatgcttt cctgacaaag gacttaacgc
     1081 aagagcatct ggaccaattg ctggtcaacc tgaggatgga agccctcttt gtgaaggaga
     1141 actttaacat ccgctgggcc gcccagacgg gattcgtgga gaacatcggc agcatcctca
     1201 aagagtacaa gcagagccga ggactgttgc caatcaagat ctgcattctt ggtcctcctg
     1261 ctgtgggaaa atccagcatc tctggagagc tggtcaagta ctacaaactg caccacatca
     1321 agataaagga tgtgatttcc gaagccatag ccaaactgga ggcgattgtc gcacccaagg
     1381 agtcaacgga agaagaggaa ggtgaagaag aggaggagga agagaacgtg gaggacgccc
     1441 aggaactcct tgatggcatc aaggaaagca tggagcagaa cgcaggtcgg ctagaagacc
     1501 aatatgtaat tcgatttgtg aaagaaaagc tcaaatctat gccttgtaag aaccaaggtt
     1561 acgttttgga tggcttccca aagacctatg atcaagcgaa agacctgttc aaccaggaag
     1621 atgaagagga agaagaggaa gtcagaggca aaatgtttcc ctatgataaa ctaattacac
     1681 ctgaatttgt gtgcaacctg gacgcctctg atgagtttct gaaggagcgc gtgatgaacc
     1741 tcccagagag tgtcgtggcg ggaactcact acagccagga ccgattcctc cgggctctga
     1801 gcaactaccg ggacatcaac acagatgacg agacggtctt caactacttt gatgaaattg
     1861 aaattcaccc catacatatt gacgtaggaa aacttgaaga tgcccagaac aggcttgcta
     1921 tcaaacagct catcaaagag attggggagc ctcggaatta tggcttaaca gatgaagaaa
     1981 aggcagaggt ggagaagaaa gctgcagagg aacgcctggc caaggaggct gctcagacgg
     2041 cagaacgtga gcacaaggag gccctggaga tggcggagaa gatagcccgc tgggaggagt
     2101 ggagtaaacg gctggaggaa gtgaagcgag aagagaggga gctgctggag gcgcagtcca
     2161 tccccctgag aaactacctg atgacctacg tgatgcctac cctcatgcag gggctcaatg
     2221 agtgctgcaa ggtgagaccc gaagaccccg tggattttct ggccgagtat ctcttcaaga
     2281 acaatcccga aatgcagtaa agactcatca gtgtgggagc ttcagaggga gagctcaagt
     2341 taaacttgta atttgaaaaa ctgcttttaa aaatgccttc ctaggggttt tttgggggga
     2401 gttgggtggg gggagtagtg agggggaatc ctagtgaagt ggaatcatta gaaaaccaca
     2461 ttgcaacgaa taactactat cccattgaaa cgatatttga aaagtaaaca gataaggcac
     2521 acctgcatag cttagggacc agtaatatta ctcttatgtc agtcacaact ctgcacacta
     2581 acacgtttgt aggaacttaa gttataacac agagttatat gctccaacag tgtccgaaat
     2641 gaaagaaatt agaaccactc atgcttgttg aaacccacga catcagctgt gatcggctcc
     2701 tgcaaggttg ctcttgagga tagggccagt attctagcca ctaagggaac tgaagagctt
     2761 gtgatgggaa acatgtgggt cgaggtaaat cctgctaccc ccaccccacc cctatcacta
     2821 caaagtgctg aatatgcacc actaattaat ttctcagtac agtcatgagt tgtgattttc
     2881 ctccattaaa aataaaagtc tggtaaaaat ctc
//
