LOCUS       NP_001094484             411 aa            linear   ROD 27-MAR-2024
DEFINITION  adherens junction-associated protein 1 precursor [Rattus
            norvegicus].
ACCESSION   NP_001094484 XP_001076803
VERSION     NP_001094484.1
DBSOURCE    REFSEQ: accession NM_001101014.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 411)
  AUTHORS   Jakob,V., Schreiner,A., Tikkanen,R. and Starzinski-Powitz,A.
  TITLE     Targeting of transmembrane protein shrew-1 to adherens junctions is
            controlled by cytoplasmic sorting motifs
  JOURNAL   Mol Biol Cell 17 (8), 3397-3408 (2006)
   PUBMED   16707570
REFERENCE   2  (residues 1 to 411)
  AUTHORS   McDonald,J.M., Dunlap,S., Cogdell,D., Dunmire,V., Wei,Q.,
            Starzinski-Powitz,A., Sawaya,R., Bruner,J., Fuller,G.N., Aldape,K.
            and Zhang,W.
  TITLE     The SHREW1 gene, frequently deleted in oligodendrogliomas,
            functions to inhibit cell adhesion and migration
  JOURNAL   Cancer Biol Ther 5 (3), 300-304 (2006)
   PUBMED   16410724
REFERENCE   3  (residues 1 to 411)
  AUTHORS   Bharti,S., Handrow-Metzmacher,H., Zickenheiner,S., Zeitvogel,A.,
            Baumann,R. and Starzinski-Powitz,A.
  TITLE     Novel membrane protein shrew-1 targets to cadherin-mediated
            junctions in polarized epithelial cells
  JOURNAL   Mol Biol Cell 15 (1), 397-406 (2004)
   PUBMED   14595118
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Aug 13, 2007 this sequence version replaced XP_001076803.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB179740.1, SRR26643298.30541.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            NMD candidate          :: translation inferred from conservation
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     Protein         1..411
                     /product="adherens junction-associated protein 1
                     precursor"
                     /note="adherens junction-associated protein 1"
                     /calculated_mol_wt=39904
     sig_peptide     1..43
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=4869
     mat_peptide     44..411
                     /product="Adherens junction-associated protein 1.
                     /evidence=ECO:0000255. /id=PRO_0000284803"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4W8E7.1)"
                     /calculated_mol_wt=39904
     Region          62..156
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4W8E7.1)"
     Region          180..388
                     /region_name="AJAP1_PANP_C"
                     /note="AJAP1/PANP C-terminus; pfam15298"
                     /db_xref="CDD:464624"
     Region          242..270
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4W8E7.1)"
     Site            284..304
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4W8E7.1)"
     Region          304..411
                     /region_name="Targeting signals. /evidence=ECO:0000250"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4W8E7.1)"
     CDS             1..411
                     /gene="Ajap1"
                     /gene_synonym="neumo48"
                     /coded_by="NM_001101014.2:160..1395"
                     /db_xref="GeneID:687031"
                     /db_xref="RGD:1590138"
ORIGIN      
        1 mwiqqllgls smpirwpgrs lgshlwilia mlqlavdfps cdslgpgpef rllsrpqrpq
       61 rlwslrtgpp trlptpawsp raaraerahg piqmqtprar rahrprdqva tlgpkggltk
      121 ppaatrssps ltsasasssm tagaaehqsl lkrgrrhthd aefndfdfhg grpttetefi
      181 awgptgdeea lesntfpggf gpttvsilqt rkttmaattt ttaastatam tlqtkgvtes
      241 ldpwkrtpvg vsttepstsp snngkdiqpp rilgetsgla vhqiititvs limviaalit
      301 tlvlknccap sghtrrnshq rkmnqqeesc qnltdftpar vpssvdifta ynetlqcshe
      361 cvrasvpvya detlhstgey kstfngnrss sadrhlipva fvsekwfeis c
//
